[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"casting\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:casting":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100596183","no-reduction-compared-to-closed-reduction-for-distal-radius-fractures-in-patients-over-65-or-older-100596183",false,"NCT07042139","No Reduction Compared to Closed Reduction for Distal Radius Fractures in Patients Over 65 or Older","A Randomized Controlled Trial Comparing No Reduction to Closed Reduction for Distal Radius Fractures in Patients 65 Years and Older (DISCLOSE Trial): A Study Protocol","DISCLOSE","Inclusion Criteria:\n\n* Age 65 years or older\n* Independent living patients\n* Displaced distal radius fracture (AO\u002FOTA 23A\u002F23C) with 15-40 degree dorsal angulation, and\u002For of shortening of the radius for more than 2 mm.\n* Associated ulnar styloid fracture is permitted\n* Low energy injury, (fall from \\\u003C1 m)\n\nExclusion Criteria:\n\n* Patient unable to provide consent\n* Patients who are actively working in a paid position\n* Volar angulation, partial articular fractures (AO\u002FOTA 23B)\n* Concomitant fracture of the ulna proximal to the base of the styloid process\n* Associated fracture or dislocation in any other body part that would affect the use of the injured distal radius\n* Distal radius fractures in both arms\n* Open injury, Gustilo 2 or higher\n* No bony contact between the main fragments\n* High energy injuries","ALL","65 Years",{"count":20,"type":21},532,"ESTIMATED","INTERVENTIONAL",[24],"NA","DISCLOSE trial is a randomized controlled trial including 532 participants with low-energy distal radius fractures. The primary objective is to evaluate whether casting without prior closed reduction is equivalent to casting following closed reduction with respect to wrist-related pain and disability, as measured by the Patient-Rated Wrist Evaluation (PRWE) score at 12 months, in patients aged 65 years or older with a displaced distal radius fracture.\n\n* Primary endpoint will be PRWE at 12 months\n* Follow-up visits are scheduled at 3 and 12 months. 5-year follow-up will be considered as an exploratory endpoint",[27,28,29],"Distal Radius Fracture","Casting","Closed Reduction",[31,32,33,34,35],"distal radius fracture","casting","closed reduction","nonoperative treatment","DISCLOSE trial","RECRUITING","2026-01-19",{"date":39,"type":40},"2026-01-21","ACTUAL",{"date":42,"type":40},"2025-08-01",{"date":44,"type":21},"2033-07-01",{"name":46,"class":47},"Tampere University Hospital","OTHER",10]