[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"catheter-blockage\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:catheter-blockage":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100578732","a-novel-ureteric-stent-in-kidney-stone-patients-and-oncology-patients-compared-to-a-conventional-jj-stent-100578732",false,"NCT06815120","A Novel Ureteric Stent in Kidney Stone Patients and Oncology Patients Compared to a Conventional JJ Stent","Two Single Arm, Multicentre Unblinded First-in-human Trials Investigating a Novel Ureteric Stent to Determine the Reduction of Encrustation, Biofilm Deposition and Complications Compared to a Conventional JJ Stent","CASSETTE","Inclusion Criteria:\n\n1. Aged 18 years or over\n2. Ureteric stents clinically indicated either due to kidney stones or abdominal\u002Fpelvic cancers compressing ureters\n3. Previous experience with ureteric stents\n4. Awaiting insersion\u002Freplacement of stents\n5. Ability to give consent\n6. Ability to interact with study documentation\n7. Sufficient English to complete study documentations and questionnaires\n\nExclusion Criteria:\n\n1. Expected survival \\\u003C4months\n2. Unfit for stent insertion\n3. Unable to comply with study processes Pregnancy","ALL","18 Years","99 Years",{"count":21,"type":22},50,"ESTIMATED","INTERVENTIONAL",[25],"NA","Urological stents and catheters often lead to inflammation, causing pain and infection in the urinary tract. Moreover, 80% of stents are associated with pain, negatively impacting on QoL and mental health. Offering novel designs with significantly lower E\\&B leads to a reduction in UTIs and improves QoL. Reducing hospital admissions (from 3 to 1 per patient, annually) would free \\>100,000 bed-nights, allowing the elderly to regain independence. Our proposed research could have a significant impact towards fulfilling the 'healthy-ageing' Grand Challenge. Additionally, the novel stent reduces prevalence of infections and therefore, of antibiotic prescriptions contributing to the Global AMR challenge.",[28,29,30],"Catheter Blockage","Oncology","Kidney Stone","RECRUITING","2026-05-06",{"date":34,"type":35},"2026-05-11","ACTUAL",{"date":37,"type":35},"2025-08-06",{"date":39,"type":22},"2026-12-31",{"name":41,"class":42},"University of Southampton","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":23,"phases":53,"briefSummary":54,"conditions":55,"keywords":60,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":74},"100452241","nylon-versus-polyurethane-epidural-catheters-in-patients-undergoing-major-orthopedic-surgery-100452241","NCT05168943","Nylon Versus Polyurethane Epidural Catheters In Patients Undergoing Major Orthopedic Surgery","Inclusion Criteria:\n\n* American Society of Anesthesiologists (ASA) physical status ≤ II\n* Age from 21 to 60 years\n* Body Mass Index (BMI) \\\u003C 35\n\nExclusion Criteria:\n\n* American Society of Anesthesiologists (ASA) physical status \\> II\n* Age \\\u003C 21 years or \\> 60 years\n* Body Mass Index (BMI) ≥ 35\n* Contraindications to regional anesthesia (including coagulopathy and infection at the injection site)\n* Uncooperative patients\n* Patients with known allergy to local anesthetics or opioids","21 Years","60 Years",{"count":52,"type":22},60,[25],"Objectives: To compare the safety and efficacy of nylon (polyamide) epidural catheter versus polyurethane epidural catheter in patients undergoing major orthopedic surgery under continuous epidural anesthesia.\n\nBackground: Continuous epidural anesthesia is the most common anesthetic technique used in orthopedic surgery. However, the use of epidural catheters is associated with complications. The insertion of the catheter may be associated with intravascular or intrathecal placement, nerve root irritation, paresthesia, kinking, hematoma, or breakage during catheter removal.\n\nPatients and Methods: This was a prospective, randomized, double-blind clinical trial; carried out on 60 patients undergoing major orthopedic surgery under continuous epidural anesthesia. Patients were randomly allocated into two equal groups; group N, using Nylon catheter, and group P, using Polyurethane catheter.",[56,57,28,58,59],"Epidural; Anesthesia","Catheter Complications","Catheter Dysfunction","Catheter Breakage",[61,62,63],"Epidural Anesthesia","Nylon (Polyamide) Epidural Catheter","Polyurethane Epidural Catheter","2026-01-09",{"date":66,"type":35},"2026-01-12",{"date":68,"type":35},"2025-07-01",{"date":70,"type":22},"2026-12-30",{"name":72,"class":73},"Damanhour Teaching Hospital","OTHER_GOV",1]