[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"caudal-block\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:caudal-block":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,43,76,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100644888","effect-of-caudal-block-on-urethrocutaneous-fistula-after-distal-hypospadias-repair-100644888",false,"NCT07675798","Effect of Caudal Block on Urethrocutaneous Fistula After Distal Hypospadias Repair","The Effect of Caudal Block on the İncidence of Urethrocutaneous Fistula After Distal Hypospadias Repair: A Multicentre, Randomized Controlled Trial","Inclusion Criteria:\n\n* Male patients aged 6-60 months\n* Diagnosed with distal hypospadias\n* Scheduled for elective hypospadias repair\n* Written informed consent obtained from parent or legal guardian\n\nExclusion Criteria:\n\n* Age \\\u003C 6 months or \\> 60 months\n* Proximal or non-distal hypospadias\n* Previous hypospadias repair\n* Skin lesions at the epidural\u002Fcaudal injection site\n* Coagulopathy\n* Known allergy to anesthetic agents, particularly bupivacaine hydrochloride\n* Spinal anomalies\n* Chronic granulomatous disease\n* Diabetes mellitus\n* Patients receiving corticosteroid therapy\n* Refusal of informed consent by parent or guardian","MALE","6 Months","60 Months",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","Hypospadias is one of the most common congenital urogenital anomalies in males, occurring in approximately 1 in every 200-300 male births. It is characterized by abnormal positioning of the urethral meatus on the ventral surface of the penis. Surgical repair is the standard treatment; however, urethrocutaneous fistula formation remains one of the most frequent and clinically significant postoperative complications, potentially requiring reoperation and causing considerable distress to both the patient and the family.\n\nCaudal nerve block is a widely used regional anesthesia technique in pediatric lower abdominal and genitourinary surgery, valued for its high analgesic efficacy, relative ease of application, and low complication profile. However, emerging evidence suggests that caudal block may be associated with an increased incidence of postoperative complications following hypospadias repair, including fistula formation and wound edema. Notably, Kundra et al. (2012) reported a fistula rate of 19.2% in patients who received caudal block, compared to 0% in those who received penile block, raising important questions about the routine use of caudal block in hypospadias surgery.\n\nThis prospective, multicenter, randomized controlled trial aims to evaluate the effect of caudal block on the incidence of urethrocutaneous fistula following distal hypospadias repair. A total of 80 male patients aged 6-60 months will be randomized 1:1 to either receive general anesthesia with caudal block or general anesthesia alone. The primary outcome is the incidence of urethrocutaneous fistula. Secondary outcomes include perioperative opioid consumption, postoperative pain scores, analgesic duration, and other surgical complications such as wound dehiscence and urethral stricture. Patients will be followed up for 3-6 months postoperatively. The study will be conducted across four centers in Turkey. Results are expected to provide evidence-based guidance on the role of caudal block in pediatric hypospadias repair.",[27,28,29],"Hypospadias","Caudal Block","Pediatric Anesthesia","RECRUITING","2026-06-23",{"date":33,"type":34},"2026-06-30","ACTUAL",{"date":36,"type":34},"2025-12-01",{"date":38,"type":21},"2026-08-15",{"name":40,"class":41},"Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital","OTHER",2,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100600597","ultrasound-guided-sacral-erector-spinae-plane-block-versus-ultrasound-guided-caudal-block-in-pediatric-undergoing-hypospadias-surgery-100600597","NCT07099560","Ultrasound Guided Sacral Erector Spinae Plane Block Versus Ultrasound Guided Caudal Block in Pediatric Undergoing Hypospadias Surgery","Comparison of Preemptive Analgesic Effect of Ultrasound Guided Sacral Erector Spinae Plane Block Versus Ultrasound Guided Caudal Block in Pediatric Undergoing Hypospadias Surgery","Inclusion Criteria\n\n* Male children aged 1-5 years\n* ASA physical status I-II\n* Scheduled for elective hypospadias repair under general anesthesia\n* Parent or legal guardian provides written informed consent\n* Able to complete postoperative assessments through 24 hours after surgery Exclusion Criteria\n* Parent\u002Fguardian refusal of participation\n* Coagulopathy or current anticoagulant therapy\n* Infection at the intended injection site (sacral\u002Fcaudal region) or systemic infection\n* Allergy\u002Fhypersensitivity to amide local anesthetics (e.g., bupivacaine) or study medications\n* Neurologic or spinal disorders or congenital sacral anomalies affecting block safety\n* Significant hepatic, renal, or cardiac disease\n* Any other condition that, in the investigator's judgment, contraindicates caudal block or sacral ESPB or could interfere with safe participation","1 Year","5 Years",{"count":53,"type":21},70,[24],"Randomized, parallel-group, assessor-blinded clinical trial at Tanta University Hospitals comparing ultrasound-guided sacral erector spinae plane block (sESPB) versus ultrasound-guided caudal epidural block for postoperative analgesia in male children (1-5 years) undergoing hypospadias repair. Seventy participants will be randomized 1:1 to receive sESPB or caudal block with 0.25% bupivacaine (0.5-1 mL\u002Fkg; maximum 20 mL) after induction of general anesthesia. The primary outcome is pain over the first 24 hours, assessed using the FLACC scale at prespecified time points. Secondary outcomes include total opioid consumption, time to first rescue analgesia, postoperative nausea and vomiting, parent\u002Fguardian satisfaction, hemodynamic trends, and predefined adverse effects (e.g., motor weakness, urinary retention, respiratory depression, hematoma, infection at injection site). Perioperative care is standardized; rescue pethidine is administered when FLACC ≥4. The trial evaluates whether sESPB provides superior or comparable analgesia with fewer adverse effects than caudal block.",[27,28,57,58],"Erector Spinae Plane Block","Pain, Postoperative",[60,61,62,63,64,65],"hypospadias","nerve block","erector spinae plane block","caudal block","pain","ultra-sound","2025-09-06",{"date":68,"type":34},"2025-09-09",{"date":70,"type":34},"2025-04-01",{"date":72,"type":21},"2026-04",{"name":74,"class":41},"Tanta University",1,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":82,"minAge":50,"maxAge":51,"enrollmentInfo":83,"targetDuration":4,"studyType":85,"phases":4,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":75},"100581182","peripheral-perfusion-index-as-an-early-predictor-of-successful-caudal-block-in-pediatric-patients-undergoing-lower-abdominopelvic-surgeries-under-general-anesthesia-100581182","NCT06846983","Peripheral Perfusion Index as an Early Predictor of Successful Caudal Block in Pediatric Patients Undergoing Lower Abdominopelvic Surgeries Under General Anesthesia","Inclusion Criteria:\n\n* Pediatric patients aging between 1-5 years of both sexes.\n* Pediatric patients posted for elective lower abdominopelvic surgeries under general anesthesia (duration of surgery under 120 minutes).\n* ASA physical status classes I - II.\n\nExclusion Criteria:\n\n* Guardian's refusal of procedure or participation in the study.\n* ASA classes III or above.\n* Infection at site of injection.\n* Neurological diseases and disorders such as (neuromuscular disease, cerebral palsy, spinal dysraphism …etc.)\n* Coagulopathy and bleeding disorders.\n* Hypersensitivity to the study medications.\n* Patients receiving vasoactive drugs or beta blockers.\n* Patients undergoing emergency surgery.\n* Patients in active clinical sepsis.","ALL",{"count":84,"type":21},60,"OBSERVATIONAL","The aim of this study is to assess early predictability of peripheral perfusion index to success of caudal block in pediatric patients undergoing lower abdominopelvic surgeries",[88,28],"Peripheral Perfusion Index",[90,63,91],"Peripheral perfusion index","predictor","2025-02-21",{"date":94,"type":34},"2025-02-26",{"date":96,"type":34},"2025-01-02",{"date":98,"type":21},"2025-12",{"name":100,"class":41},"Ain Shams University",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":82,"minAge":108,"maxAge":109,"enrollmentInfo":110,"targetDuration":4,"studyType":22,"phases":112,"briefSummary":113,"conditions":114,"keywords":116,"overallStatus":120,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":75},"100566284","efficacy-of-interventional-methods-used-in-the-treatment-of-coccydynia-100566284","NCT06653179","Efficacy of Interventional Methods Used in the Treatment of Coccydynia","Comparison of the Efficacy of Sacral Erector Spinae Plane Block and Caudal Epidural Injection on Chronic Coccydynia: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Chronic coccydynia unresponsive to conservative treatment\n* Male and female population aged 18-70\n* No previous interventional procedure performed during the treatment process\n\nExclusion Criteria:\n\n* Coagulation disorders\n* Infections in the areas to be treated\n* Allergy to local anesthesia\n* Socio-cultural inadequacy\n* Mental retardation\n* Pregnancy\n* Previous interventional procedure performed\n* Patient refusal of the interventional procedure\n* Presence of malignancy in the coccygeal region\n* Previous surgery in the coccygeal region","18 Years","70 Years",{"count":111,"type":21},94,[24],"This study aims to evaluate the effectiveness of sacral erector spinae plane block and caudal epidural injection in patients with coccydynia resistant to conservative treatments. Ultrasound guidance will be used for sacral erector spinae plane block, while fluoroscopic guidance will be applied for caudal epidural injection. The effectiveness of these treatments will be assessed through face-to-face questionnaires, the Numerical Rating Scale and the Paris Functional Coccydynia Scale at first, fourth and twelfth-week follow-ups.",[115,57,28],"Coccydynia",[117,118,119],"Sacral Erector Spinae Plane Block","Caudal. Epidural Injection","Chronic Coccydynia","NOT_YET_RECRUITING","2024-10-22",{"date":123,"type":34},"2024-10-23",{"date":125,"type":21},"2024-11-15",{"date":127,"type":21},"2025-11-15",{"name":129,"class":130},"Ankara Etlik City Hospital","OTHER_GOV"]