[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cellulitis-of-leg\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cellulitis-of-leg":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100484128","phase-3-cellulitis-optimal-antibiotic-treatment-100484128",false,"NCT05584007","Cellulitis Optimal Antibiotic Treatment","A Blinded, Non-inferiority Phase III Trial of 5 Versus 7 Days of Oral Flucloxacillin in Primary Care Patients With Lower Limb Cellulitis","COAT","Inclusion Criteria:\n\n* Must be aged 18 years or older\n* Currently showing symptoms of cellulitis (such as pain, tenderness, redness, other change in skin color, warmth to touch) in one leg for 10 days or less\n* Pain rated as 3\u002F10 or higher on a numerical rating scale (0-10) at baseline assessment\n* Be willing to be randomized to either trial arm (5-day or 7-day treatment)\n* Able to complete trial procedures in the English language.\n\nExclusion Criteria:\n\n* Have penicillin allergy\n* Have bilateral cellulitis\n* Have had antibiotics for cellulitis within the past month\n* Have post-operative cellulitis (within 30 days of operative procedures on the same leg)\n* Have cellulitis resulting from human\u002Fanimal bite injury\n* Have Cellulitis associated with chronic (\\>6 weeks) leg ulceration\n* Require immediate hospital admission or out-patient intravenous antibiotic therapy","ALL","18 Years",{"count":20,"type":21},334,"ESTIMATED","INTERVENTIONAL",[24],"PHASE3","To determine whether a short course of oral flucloxacillin (5 days) is non-inferior to a standard course (7 days) in terms of pain over days 6-14 (indicative of persistence or recurrence associated with the symptoms of most importance to patients) in adults with cellulitis of the leg presenting in primary care.",[27],"Cellulitis of Leg",[29,30,31,32,33],"Primary care","Antibiotic treatment","Antibiotic resistance","Pain","Cost consequences","RECRUITING","2026-05-14",{"date":37,"type":38},"2026-05-15","ACTUAL",{"date":40,"type":38},"2023-08-29",{"date":42,"type":21},"2027-07",{"name":44,"class":45},"University of Southampton","OTHER"]