[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"central-obesity\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:central-obesity":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,97],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100572125","effect-of-ultrasound-cavitation-on-insulin-resistance-in-patients-with-central-obesity-in-female-100572125",false,"NCT06729203","Effect of Ultrasound Cavitation on Insulin Resistance in Patients with Central Obesity in Female","Inclusion Criteria:\n\n* Female subjects with central obesity.\n* Female participants aged between 25 to 40 years.\n* Body Mass Index (BMI) ranged from 30 to 35 kg\u002Fm2 as high BMI indicates more obesity and central obesity.\n* Waist circumference greater than 88 cm, indicative of abdominal obesity.\n* Diagnosed with insulin resistance (HOMA-IR \\> 2.9).\n* Sedentary lifestyle, defined as engaging in less than 150 minutes of moderate-intensity physical activity per week.\n* Willingness to provide informed consent and comply with study procedures.\n\nExclusion Criteria:\n\n* • Subjects diagnosed with DM (HbA1c more than 6.5%).\n\n  * History of metabolic disorders such as type 1 diabetes or thyroid disorders.\n  * Subjects with BMI less than 30 kg\u002Fm2.\n  * Subjects diagnosed with heart disease, liver as well as kidney diseases.\n  * Subjects who take oral contraceptives.\n  * Subjects with gestational Diabetes.\n  * Pregnant or breastfeeding women were excluded from the study.\n  * Use of weight-loss medications or supplements within the past six months.\n  * Previous surgical procedures for weight loss or body contouring.\n  * Contraindications to ultrasound therapy (e.g., metal implants in the abdomen, active skin infections).\n  * Participation in another clinical trial within the last three months.","FEMALE","25 Years","40 Years",{"count":19,"type":20},52,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study was to investigate the effect of ultrasound cavitation on insulin resistance, HbA1c and skin fold in patients with abdominal central obesity.",[26],"Central Obesity",[28,29,30,31],"central obesity","ultrasound cavitation","insulin resistance","HOMA ir","RECRUITING","2024-12-08",{"date":35,"type":36},"2024-12-11","ACTUAL",{"date":38,"type":20},"2024-12-01",{"date":40,"type":20},"2025-12-01",{"name":42,"class":43},"Cairo University","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":52,"minAge":53,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":77,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":44},"100569420","osaka-cardiometabolic-epidemiological-study-ohtori-study-part-2-100569420","NCT06694012","Osaka Cardiometabolic Epidemiological Study: Ohtori Study Part 2","OCES-2","Inclusion Criteria:\n\n\\-\n\nExclusion Criteria:\n\n* Women who may be pregnant","ALL","20 Years",{"count":55,"type":20},2000,"OBSERVATIONAL","The aim of this study is to investigate the relationship between body fat distribution measured by CT scan and related risk factors with the risk of incident metabolic and cardiovascular disease in a prospective cohort study of Japanese men and women. The investigators will also investigate novel risk factors for metabolic and cardiovascular disease using molecular weight-based metallomics analysis.",[59,60,61,62,63,64,65,66,67,68,69,70,26,71,72,73,74,75,76],"Type 2 Diabetes Mellitus (T2DM)","Type 2 Diabetes","Diabetes Mellitus","Hypertension","Hyperglycemia","Hyperlipidemia","Dyslipidemia","Hyperuricemia or Gout","Hyperuricemia, Gout","Obesity","Obesity\u002FEpidemiology","Obesity, Abdominal","Visceral Fat","Chronic Kidney Disease(CKD)","Atherosclerosis","Metabolic Syndrome","Hepatic Steatosis","Insulin Sensitivity\u002FResistance",[78,62,64,65,79,80,81,82,83,84,85,74,86,87],"Type 2 Diabetes Mellitus","Hyperuricemia","obesity","Abdominal obesity","Visceral fat","Visceral adiposity","Chronic Kidney Disease","Japanese","Insulin Sensitivity","Insulin Resistance","2024-11-29",{"date":90,"type":36},"2024-12-04",{"date":92,"type":36},"2024-11-01",{"date":94,"type":20},"2050-03-31",{"name":96,"class":43},"Osaka Metropolitan University",{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":103,"minAge":17,"maxAge":104,"enrollmentInfo":105,"targetDuration":4,"studyType":21,"phases":107,"briefSummary":108,"conditions":109,"keywords":4,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":44},"100566704","ultrasound-lipolysis-versus-cryolipolysis-on-lipid-profile-levels-in-centrally-obese-middle-aged-men-100566704","NCT06658639","Ultrasound Lipolysis Versus Cryolipolysis On Lipid Profile Levels In Centrally Obese Middle Aged Men","Inclusion Criteria:\n\n1. Obese men with middle age range will be 40-60 years.\n2. Obese men with central obesity.\n3. Body mass index (BMI) greater than 30 Kg \\\\m2.\n4. Waist circumference will be \\>94 cm.\n5. Waist to hip ratio more than 0.9\n\nExclusion Criteria:\n\n1. Chronic respiratory disorders and cardiovascular problems.\n2. Diabetic patients.\n3. Presence of skin diseases in abdominal regions that prevent the use of ultra sound or cryolipolysis therapy.\n4. Men with kidney or liver diseases.\n5. Tumor diseases\n6. Lesions of higher center leading to obesity.\n7. History of active or chronic infectious, autoimmune disease.\n8. History of abdominal surgeries.","MALE","60 Years",{"count":106,"type":20},66,[23],"The study compares the effects of ultrasound lipolysis and cryo lipolysis on cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, body mass index, skin thickness, waist circumference, and waist hip ratio in centrally obese middle aged men. It also investigates the impact of ultrasound lipolysis on skin thickness, waist circumference, and waist hip ratio.",[110,111,112,26],"Ultrasound Lipolysis","Cryolipolysis","Lipid Profile","NOT_YET_RECRUITING","2024-10-24",{"date":116,"type":36},"2024-10-26",{"date":118,"type":20},"2024-11-05",{"date":120,"type":20},"2025-04-05",{"name":42,"class":43}]