[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"central-sleep-apnea\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:central-sleep-apnea":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,68],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100637904","natural-history-of-central-and-mixed-sleep-apneas-followed-by-maxillomandibular-advancement-for-obstructive-sleep-apnea-100637904",false,"NCT07596719","Natural History of Central and Mixed Sleep Apneas Followed by Maxillomandibular Advancement for Obstructive Sleep Apnea","CMAI","Inclusion Criteria:\n\n* Adults aged 18 years or older;\n* Mild to severe OSA as determined by a polysomnography (PSG) preoperatively;\n* Completion of MMA for OSA treatment;\n* Subjects with preoperative and postoperative PSG;\n* Patients who are present with MMA treatment-related central apneas postoperatively\n\nExclusion Criteria:\n\n* Patients who underwent other adjunctive procedures at the time of MMA (e.g., multi-piece Le Fort osteotomy, TMJ reconstruction);\n* Previous history of orthognathic surgery;\n* Cleft palate and syndromic patients.","ALL","18 Years",{"count":19,"type":20},60,"ESTIMATED","OBSERVATIONAL","The goal of this observational prospective cohort study is to learn about the natural course of central and mixed sleep apneas that develop after maxillomandibular advancement (MMA) surgery for obstructive sleep apnea (OSA) in adult patients.\n\nThe main question it aims to answer is:\n\nDo central and mixed apneas resolve, partially resolve, or persist in the long term after MMA?\n\nParticipants will:\n\nUndergo a first postoperative polysomnography (PSG) at 3-6 months after MMA (part of standard care).\n\nBe invited into the study if central\u002Fmixed apneas are detected (CMAI% \\>25%). Undergo a second PSG at least 12 months after MMA (extra study procedure)",[24,25,26,27],"Sleep Apnea Syndrome (OSAS)","Central Sleep Apnea","Maxillomandibular Advancement Surgery","Orthognathic Surgical Procedures",[29,30,25],"OSA","MMA","NOT_YET_RECRUITING","2026-05-13",{"date":34,"type":35},"2026-05-19","ACTUAL",{"date":37,"type":20},"2026-12-01",{"date":39,"type":20},"2027-12-31",{"name":41,"class":42},"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":52,"targetDuration":54,"studyType":21,"phases":4,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":67},"100333456","belgian-central-sleep-apnea-registry-100333456","NCT03621566","Belgian Central Sleep Apnea REgistry","Belgian Central Sleep Apnea REgistry (B-CARE)","B-CARE","Inclusion Criteria:\n\n* Age ≥ 18 years old\n* An apnea\u002Fhypopnea index ≥ 15\u002Fh of sleep and proportion of non-obstructive events \\> 50%, derived from polysomnography (diagnostic or during (PAP) treatment)\n* Written informed consent provided\n\nExclusion Criteria:\n\n\\- Patients with mental disability making it impossible to understand the study protocol",{"count":53,"type":20},1500,"5 Years","This study evaluates different factors that determine the treatment choice and treatment compliance in patients with central sleep apnea. All patients will receive routine care (registry).",[25],"RECRUITING","2024-07-02",{"date":60,"type":35},"2024-07-03",{"date":62,"type":35},"2018-06-25",{"date":64,"type":20},"2028-06-25",{"name":66,"class":42},"Universitaire Ziekenhuizen KU Leuven",14,{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":75,"targetDuration":4,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":4,"overallStatus":57,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":83,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":43},"100279634","interface-selection-for-adaptive-servo-ventilation-100279634","NCT02919930","Interface Selection for Adaptive Servo Ventilation","Interface Selection for Adaptive Servo Ventilation: A Randomized Controlled Study","Inclusion Criteria:\n\n* Patients with central sleep apnea, not responding to treatment with CPAP\n* Indication for treatment with ASV\n\nExclusion Criteria:\n\n* Patients \\\u003C 18 years old",{"count":76,"type":20},15,"INTERVENTIONAL",[79],"NA","The purpose of this study is to compare the effects of nasal and oronasal interfaces during ASV treatment on sleep efficiency and sleep architecture. Therefore, patients starting treatment with ASV, will be randomized between two groups. In the first group, patients will use a nasal interface during the first night and an oronasal interface during the second night. In the second group, patients will use an oronasal mask first and a nasal mask during the second night. The results of this trial will have major impact on future clinical practice as it would deliver prediction rules to choose the correct interface immediately.",[25,82],"ASV",{"date":60,"type":35},{"date":85,"type":35},"2015-02",{"date":87,"type":20},"2025-01",{"name":66,"class":42}]