[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cerebral-microvascular-dysfunction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cerebral-microvascular-dysfunction":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100560632","prospective-observation-on-cerebral-microvascular-structure-and-function-100560632",false,"NCT06579677","PRospective Observation on CErebral microvaScular Structure and Function","PRospective Observation on CErebral microvaScular Structure and Function (PROCESS): a Population-based Prospective Cohort Study","PROCESS","Inclusion Criteria:\n\n1. Community-dwelling adults aged 50-75 years;\n2. Registered Beijing household residents or residents who can be followed up stably in their own communities for a long period;\n3. Subjects with written informed consents.\n\nExclusion Criteria:\n\n1. Residents with moderate to severe disabilities (MRS ≥3), mental illness, stroke, dementia, and other serious neurological disorders (e.g., encephalitis, Parkinson's disease, epilepsy, brain tumors, and rare genetic diseases of the nervous system);\n2. Life expectancy of ≤4 years due to serious diseases such as end-stage cancer;\n3. Contraindications to magnetic resonance imaging such as implanted devices (e.g., pacemakers, defibrillators, and others);\n4. Residents who are participating in other studies.",true,"ALL","50 Years","75 Years",{"count":22,"type":23},3500,"ESTIMATED","OBSERVATIONAL","This is a population-based prospective cohort study, aiming to assess the prevalence, distributional characteristics, and dynamic change of cerebral small vessel dysfunction in a Chinese community population using advanced vascular imaging techniques; meanwhile to investigate the effect of vascular risk factors on cerebral small vessel dysfunction, cardiovascular and cerebrovascular diseases, cognitive dysfunction, and mortality.",[27,28,29,30,31,32],"Cerebral Microvascular Dysfunction","Cerebral Small Vessel Diseases","Cognitive Dysfunction","Cerebrovascular Disorders","Cardiovascular Diseases","Population","RECRUITING","2025-01-02",{"date":36,"type":37},"2025-01-06","ACTUAL",{"date":39,"type":37},"2024-10-18",{"date":41,"type":23},"2032-10",{"name":43,"class":44},"Beijing Tiantan Hospital","OTHER",2]