[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cerebral-palsy-children\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cerebral-palsy-children":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,44,86,113,147,175],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100638064","rehabilitation-assessment-of-motor-function-in-cerebral-palsy-using-explainable-ai-100638064",false,"NCT07629024","Rehabilitation Assessment of Motor Function In Cerebral Palsy Using Explainable AI","Rehabilitation Assessment of Motor Function in Ambulatory Children With Cerebral Palsy Using Explainable Machine Learning","Inclusion Criteria:\n\n* Age 4 to18 years\n* Diagnosed any motor type of cerebral palsy (spastic, dyskinetic, ataxic, mixed),)\n* GMFCS levels I -III (able to walk with or without an assistive device).\n* All participants must be able to ambulate at least 10 meters with or without an assistive device.\n* Capable of following simple verbal instructions.\n* Parental informed consent and child assent\n\nExclusion Criteria:\n\n* Recent orthopedic or neurosurgical interventions (\\\u003C6 months).\n* Uncontrolled seizures affecting gait.\n* Non-ambulatory (GMFCS IV-V) or cognitive impairments preventing cooperation.","ALL","4 Years","18 Years",{"count":20,"type":21},200,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to develop and validate an AI-based prediction model for functional mobility and gait outcomes in children with cerebral palsy using low-cost clinical and gait data collected in rehabilitation settings in Pakistan. The study aims to determine whether machine learning models can accurately predict mobility status, gait symmetry, and functional independence in ambulatory and non-ambulatory children with cerebral palsy.\n\nThe main questions it aims to answer are:\n\n* Can clinical and gait-related variables accurately predict functional mobility and gait outcomes in children with spastic cerebral palsy?\n* Can video-based assessment tools provide clinically useful data for AI-based rehabilitation assessment in low-resource settings?\n\nResearchers will analyze clinical, functional, and gait data to identify patterns associated with mobility limitations and rehabilitation outcomes.\n\nParticipants will:\n\n* Undergo clinical and functional assessments, including measures of balance, mobility, posture, and functional independence.\n* Perform gait and movement tasks while data are collected using AI-based video analysis tools.\n* Participate in routine rehabilitation sessions while their movement and functional performance are recorded for analysis.\n* Provide demographic and clinical information relevant to cerebral palsy severity and functional status.",[25],"Cerebral Palsy Children",[27,28,29,30],"CP Assesment","Explainable machine learning","Gait symmetry","Functional independence","NOT_YET_RECRUITING","2026-06-23",{"date":34,"type":35},"2026-06-26","ACTUAL",{"date":37,"type":21},"2026-06-10",{"date":39,"type":21},"2027-12-30",{"name":41,"class":42},"Riphah International University","OTHER",4,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":16,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":57,"studyType":22,"phases":4,"briefSummary":58,"conditions":59,"keywords":69,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":43},"100581994","assessing-intellectual-and-motor-outcomes-in-high-risk-infants-100581994","NCT06857539","Assessing Intellectual and Motor Outcomes in High-risk Infants","The ELEVATE Program for Prediction, Early Detection & Intervention in Cerebral Palsy","AIM-High","Inclusion Criteria (High Risk Group) :\n\n* Legal guardians must be able and willing to give written informed consent and to comply with the requirements of this study protocol.\n* All infants considered high risk for a diagnosis of cerebral palsy and neuro-developmental impairment will be eligible, specifically including:\n\n  * All preterm infants born ≤32 weeks Post Menstrual Age or ≤1500 gm birth weight\n  * All encephalopathic infants\n  * Neurological risk factors (e.g., cerebral birth defect, injury\u002Fmalformation on neuroimaging, persistently abnormal neurological exam)\n\n(Control Group)\n\n-A control arm will also be recruited.\n\nExclusion Criteria:\n\n* Death prior to discharge from the neonatal unit (High-Risk Infants only)\n* No parental consent (High-Risk and Control Infants)",true,"0 Days","4 Months",{"count":56,"type":21},600,"30 Months","Cerebral palsy (CP) is a condition when a baby has a brain injury that affects their movement and muscle tone. Some people with CP can have other developmental issues, like learning impairments, but many do not and have isolated issues with their motor skills. Some newborns are at higher risk of developing CP, including babies born prematurely, those who have an injury to their brain, and those who have an abnormal neurological examination. However, most babies with a higher risk of CP do not develop CP. The problem is that doctors can't tell early on who will and who will not develop CP, they can only say who has a risk of it. Therefore, these babies are followed up in out-patient clinics to see how they are progressing, usually by a neonatologist (baby doctor), often a physiotherapist, and some may also be referred to services in the community like the Early Intervention Team. If there is a significant concern, doctors will often perform a scan of the baby's brain to provide more information. Even with all this follow-up, it still usually takes at least 12 months, and can be up to 2 years, to diagnose a child as having CP.\n\nIn this study the aim is to try and reduce the age of diagnosis of CP by assessing children in high-risk out-patient clinics using novel and specific examinations. We would also like to improve our ability to predict who will need help with learning, language or other non-motor outcomes. This study is being conducted at several hospitals in Ireland, including Cork University Maternity Hospital (CUMH), The Rotunda Hospital and the Coombe Women and Infants Hospital. It is being coordinated by the In4kids network and will be conducted in the INFANT Centre\u002F University College Cork (UCC). The study has been funded by Research Ireland and the Cerebral Palsy Foundation, USA.",[60,61,25,62,63,64,65,66,67,68],"Cerebral Palsy","Cerebral Palsy (CP)","High-risk Infants","Intellectual and Developmental Disabilities","Motor Impairment","Cognitive Development","HIE - Hypoxic - Ischemic Encephalopathy","Preterm","Prematurity; Extreme",[60,70,71,72,73,74,75],"High-Risk Infant Follow-up","Motor Difficulty","Intellectual Delay","Cognitive Impairment","Hypoxic--Ischaemic Encephalopathy","Prematurity","RECRUITING","2026-05-08",{"date":79,"type":35},"2026-05-13",{"date":81,"type":35},"2025-03-21",{"date":83,"type":21},"2030-07-31",{"name":85,"class":42},"University College Cork",{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":92,"eligibilityCriteria":93,"healthyVolunteers":52,"sex":16,"minAge":94,"maxAge":95,"enrollmentInfo":96,"targetDuration":4,"studyType":98,"phases":99,"briefSummary":101,"conditions":102,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":112},"100578457","evaluating-the-effects-of-an-electrical-stimulator-on-improving-the-walking-ability-of-children-with-cerebral-palsy-100578457","NCT06811545","Evaluating the Effects of an Electrical Stimulator on Improving the Walking Ability of Children With Cerebral Palsy","Exploring the Effects of Multi-Joint Neuromuscular Electrical Stimulation on Training Gait of Children With Cerebral Palsy","CP","\\*Inclusion Criteria\\*\n\nCP Group:\n\n* Age 7-18\n* Diagnosis of spastic diplegic cerebral palsy (CP)\n* GMFCS level I-III (be able to walk with or without assistive devices)\n* MIGR \\\u003C 40% femoral head covering in acetabulum\n* Crouch, equinus, or jump gait\n* At least 0° passive dorsiflexion range of motion (ROM)\n* Sufficient visuoperceptual, cognitive, and communication skills\n* Seizure-free or well-controlled seizures\n* No other neurological or musculoskeletal disorders (e.g. dystonia, severe scoliosis, hip instability\n* Ability to travel to the University of Nebraska at Omaha two times\n* Ability to communicate pain or discomfort\n* Ability to obtain child assent and obtain parent\u002Fguardian consent\n\nHealthy adults (control) group:\n\n* Adults aged 20 to 40\n* Adults with good physical health\n* Adults with the ability to follow verbal instructions\n* Adults with the ability to walk on a treadmill for 15 minutes\n* No orthopedic surgery on the lower limb within the past 3 months\n\n\\*Exclusion Criteria\\*\n\nCP Group:\n\n* Diagnosis of athetoid or ataxic cerebral palsy (CP)\n* Scoliosis with primary curve \\> 49%\n* Spinal fusions extending into the pelvis\n* Lower Extremity (LE) joint instability or dislocation\n* Severe tactile hypersensitivity\n* LE botulinum injections in the past 6 mo\n* Implanted medical device contraindicative of functional electrical stimulation (FES)\n* Pregnancy\n* Severe LE spasticity (Modified Ashworth Scale score of 4 or greater)\n* History of pulmonary disease limiting exercise tolerance (Asthma Control Test screen)\n* History of cardiac disease (American Heart Association, AH,) screen)\n* Excessive LE joint pain during walking\n* Severely limited range of joint motion\u002F irreversible muscle contractures, i.e.\\> 10° knee flexion, \\>15° hip flexion contractures, or \\>5° plantarflexion contractures\n* LE surgery or significant injury within 1 yr.\n\nHealthy adults (control) group:\n\n* Adults with any chronic illnesses or medical conditions that could impact their health.\n* Adults with significant behavioral or emotional issues that could indicate developmental disorders or psychological conditions.\n* Adults with diagnosed developmental disorders (e.g., autism, ADHD, learning disabilities)\n* Adults with surgery on their lower limb within the past 3 months.","7 Years","40 Years",{"count":97,"type":21},65,"INTERVENTIONAL",[100],"NA","The goal of this study is to see if gentle electrical stimulation can help children with cerebral palsy (CP) walk more easily. This stimulation, called neuromuscular electrical stimulation (NMES), sends small pulses to muscles to help them activate. Researchers will test different ways of using NMES to find out which method works best.\n\nParticipants will walk on a treadmill at a comfortable speed while NMES is applied to leg muscles. The study will compare different stimulation settings to see which one helps the most.",[25,103],"Healthy Adults","2026-05-06",{"date":77,"type":35},{"date":107,"type":21},"2026-05",{"date":109,"type":21},"2029-07",{"name":111,"class":42},"University of Nebraska",1,{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":4,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":16,"minAge":120,"maxAge":4,"enrollmentInfo":121,"targetDuration":4,"studyType":98,"phases":123,"briefSummary":124,"conditions":125,"keywords":131,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":137,"lastUpdatePostDateStruct":138,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":146},"100609900","implementing-powered-mobility-in-early-childhood-settings-for-children-with-cerebral-palsy-100609900","NCT07220590","Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy","Bridging the Gap: Implementing A Powered Mobility Intervention Into Early Childhood Settings for Young Children With Cerebral Palsy (GMFCS IV-V)","Inclusion Criteria:\n\nChildren:\n\n1. Diagnosis of cerebral palsy or similar motor impairment\n2. Gross Motor Function Classification System (GMFCS) Levels IV-V\n3. Age 12 to 32 months at enrollment\n4. Enrolled in early intervention services\n\nCaregivers:\n\n1. Parent or legal guardian of an enrolled child participant\n2. Age 18 years or older\n3. English- or Spanish-speaking\n4. Able and willing to participate in home-based data collection, including caregiver coaching sessions, completion of surveys, and video-recorded sessions\n5. Able to provide informed consent\n\nTherapists:\n\n1. Licensed physical therapist or occupational therapist\n2. Employed at participating early intervention or early childhood special education settings\n3. Provide services to children with cerebral palsy or motor delays\n4. No prior powered mobility intervention training required\n5. Willing to complete powered mobility implementation training and participate in study assessments\n\nExclusion Criteria:\n\n1. Inability or unwillingness to provide informed consent\n2. Inability to complete required study procedures","1 Year",{"count":122,"type":21},24,[100],"The goal of this clinical trial is to learn if a therapist training program can help providers in Part C Early Childhood Settings use powered mobility (PM) with young children who have cerebral palsy (Gross Motor Function Classification System Levels IV-V). The study will also look at whether this training is practical and useful for therapists, families, and children.\n\nThe main questions it aims to answer are:\n\n1. Can therapists successfully use the training to provide powered mobility interventions in home and early childhood settings?\n2. Do families and children find the intervention acceptable and helpful?\n3. What benefits do children show in mobility, participation, and engagement after using powered mobility?\n\nIn this study, therapists and families will:\n\n1. Take part in a training program about how to use powered mobility with young children\n2. Use powered mobility devices (Permobil Explorer Mini) with children during everyday routines\n3. Complete surveys, interviews, and observations about their experiences",[25,126,127,128,129,130],"Motor Disabilities","Developmental Disability","Rehabilitation","Early Intervention","Assistive Technology",[132,133,134,135,136],"Power Mobility","Implementation Science","Community-engaged research","Caregiver coaching","Pediatric Rehabilitation","2025-12-30",{"date":139,"type":35},"2026-01-02",{"date":141,"type":21},"2026-01-01",{"date":143,"type":21},"2028-09-30",{"name":145,"class":42},"Oregon Health and Science University",3,{"id":148,"slug":149,"hasResults":11,"nctId":150,"briefTitle":151,"officialTitle":152,"acronym":4,"eligibilityCriteria":153,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":154,"targetDuration":4,"studyType":98,"phases":156,"briefSummary":157,"conditions":158,"keywords":159,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":165,"lastUpdatePostDateStruct":166,"startDateStruct":168,"completionDateStruct":170,"leadSponsor":172,"locationsCount":112},"100585182","effects-of-hydrotherapy-in-children-with-cerebral-palsy-100585182","NCT06899035","Effects of Hydrotherapy in Children With Cerebral Palsy","Evaluation of the Effects of Hydrotherapy on Balance and Selective Motor Control in Children With Cerebral Palsy","Inclusion Criteria:\n\n* Diagnosed with Cerebral Palsy by a specialist physician\n* Aged between 4-18 years\n* Cooperative with physiotherapy applications\n* Gross Motor Function Classification System (GMFCS) levels 1-4\n* Willing to participate in the study and undergo assessments\n\nExclusion Criteria:\n\n* Mental retardation or insufficient cognitive function to comply with study assessments\n* GMFCS level 5\n* Presence of an intrathecal baclofen pump for spasticity treatment or history of soft tissue and\u002For bone surgery\n* Active infection or localized skin infection at the injection site\n* History of active seizures\n* Presence of contractures\n* Serious systemic disease that may prevent exercise participation\n* Injury and\u002For surgery within the last 6 months\n* Botulinum toxin injection within the last 6 months\n* Contraindications to hydrotherapy, including severe fear of water, behavioral problems, shortness of breath at rest, infection, incontinence, known chlorine allergy, open wounds, acute systemic illness, epilepsy, tracheostomy, permanent drains, immunodeficiency.",{"count":155,"type":21},36,[100],"The goal of this observational study is to learn the effects of hydrotherapy in children with cerebral palsy. It aims to answer if hydrotherapy is affective on balance and selective motor control of the children with cerebral palsy.",[25],[160,161,162,163,164],"hydrotherapy","rehabilitation","balance","selective motor control","cerebral palsy","2025-03-26",{"date":167,"type":35},"2025-03-27",{"date":169,"type":35},"2025-01-22",{"date":171,"type":21},"2025-12-15",{"name":173,"class":174},"Gaziosmanpasa Research and Education Hospital","OTHER_GOV",{"id":176,"slug":177,"hasResults":11,"nctId":178,"briefTitle":179,"officialTitle":180,"acronym":4,"eligibilityCriteria":181,"healthyVolunteers":11,"sex":16,"minAge":182,"maxAge":183,"enrollmentInfo":184,"targetDuration":4,"studyType":98,"phases":186,"briefSummary":187,"conditions":188,"keywords":4,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":189,"lastUpdatePostDateStruct":190,"startDateStruct":192,"completionDateStruct":194,"leadSponsor":196,"locationsCount":112},"100565084","effects-of-universal-exercise-unit-therapy-with-task-oriented-training-in-cp-children-100565084","NCT06637579","Effects of Universal Exercise Unit Therapy With Task-oriented Training in CP Children","Effects of Universal Exercise Unit Therapy With Task-oriented Training on Lower Extremity Gross Motor Function and Balance in Cerebral Palsy Children","Inclusion Criteria:\n\n* Children who were spastic and able to understand and follow commands. Children aged 5-15 years old. Gross Motor Function Classification System (GMFCS) level I-III. Youngsters are capable of walking and standing on their own.\n\nExclusion Criteria:\n\n* Children with severe physical limitations and disabilities. Children with planned surgeries in the next 6 months. Any musculoskeletal or orthopedic conditions limiting participation in exercise programs.\n\nKids with planned surgical or medical surgeries during the study period. Children with impaired cognition. Children with hearing impairment and visual impairment.","5 Years","15 Years",{"count":185,"type":21},80,[100],"Cerebral palsy is a problem that affects the development and motor skills caused by early non-progressive central nervous system damage. Muscle rigidity, spasticity, fragility, uncontrolled movement, or a combination of these abnormalities characterized it. Therapeutic usage of the universal exercise unit is common. Also called a spider cage or monkey cage. This device helps people with motor problems, especially cerebral palsy. This metal 3-dimensional contraption uses wires, rubber bands, pulleys, weights, and belts. The goal is to engage the vestibular and proprioceptive systems, which are necessary for balance, coordination, and awareness.",[25],"2024-10-10",{"date":191,"type":35},"2024-10-15",{"date":193,"type":35},"2024-01-01",{"date":195,"type":21},"2024-11",{"name":41,"class":42}]