[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cervical-radiculopathy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cervical-radiculopathy":26},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,27,0,25,[9,52,83,110,143,168,188,215,239,267,303,324,344,368,386,405,425,451,489,514,537,556,582,600,620],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":32,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100617479","assessment-of-upper-extremity-proprioception-in-patients-with-cervical-radiculopathy-100617479",false,"NCT07319156","Assessment of Upper Extremity Proprioception in Patients With Cervical Radiculopathy","Inclusion Criteria:\n\n* Being between 18 and 65 years of age\n* Presence of radicular pain diagnosed through clinical examination and cervical -MRI imaging Patients with cervical MRI findings demonstrating cervical disc herniation at least at one level consistent with their symptoms\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* History of cervical physical therapy within the past year\n* Symptoms or diagnosis of upper-extremity entrapment neuropathy\n* Patients with documented vitamin B12 or vitamin D deficiency within the last 2 years in available medical records\n* History of cervical surgery or cervical trauma\n* History of upper-extremity surgery or trauma\n* Individuals with intellectual disability\n* Presence of major psychiatric comorbidity\n* Diagnosis of polyneuropathy\n* Diagnosis of Diabetes Mellitus\n* Diagnosis of fibromyalgia\n* Use of medications that may impair proprioception\n* Pregnancy\n* Refusal to provide informed consent",true,"ALL","18 Years","65 Years",{"count":21,"type":22},58,"ESTIMATED","OBSERVATIONAL","There is no study in the current literature that systematically investigates the extent of upper-extremity proprioceptive impairment in patients with radicular neuropathic symptoms secondary to cervical disc herniation, nor its association with clinical findings. Although existing reviews emphasize proprioceptive deficits in populations with neck pain or cervical spondylosis, no studies specifically address the subgroup of cervical disc-related radiculopathy. This gap in knowledge hinders the integration of proprioceptive assessments with upper-extremity functional outcome measures in diagnostic and rehabilitative processes, suggesting a need for more specific data to guide sensory-motor training approaches. The primary aim of the present study is to assess upper-extremity proprioception in patients with cervical radiculopathy by comparing them with a healthy control group. The secondary aim is to examine the relationship between upper-extremity proprioception and clinical outcomes, including parameters such as pain and functional status.",[26,27,28,29,30,31],"Cervical Radiculopathy","Proprioception","Cervical Disc Herniation","Proprioception Reaching Test","Pro-reach","Upper Extremity",[33,34,35,36,37,38],"cervical radiculopathy","proprioception","cervical disc herniation","proprioception reaching test","pro-reach","upper extremity","RECRUITING","2026-06-02",{"date":42,"type":43},"2026-06-04","ACTUAL",{"date":45,"type":43},"2025-12-20",{"date":47,"type":22},"2026-12-20",{"name":49,"class":50},"Marmara University","OTHER",1,{"id":53,"slug":54,"hasResults":12,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":12,"sex":17,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":68,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":51},"100639009","effects-of-drt-on-neck-pain-rom-and-chest-expansion-in-patients-with-cr-100639009","NCT07628348","Effects of DRT on Neck Pain, ROM, and Chest Expansion in Patients With CR","Effects of Diaphragmatic Release Technique on Neck Pain, Range of Motion, and Chest Expansion in Patients With Cervical Radiculopathy","Inclusion Criteria:\n\n* Presence of unilateral neck pain and paresthesia symptoms for about 2 months\n* Presence of posterolateral disc herniation at the C4-C7 level.\n* A positive spurling test\n* Positive upper limb neural tension tests for the median and ulnar nerve\n* Cervical rotation towards the painful side of less than 60 degrees\n* Chest Expansion of less than 4 cm\n\nExclusion Criteria:\n\n* Any tumor\n* Fracture\n* Osteoporosis\n* Scoliosis\n* Cervical and shoulder instability\n* Diabetic neuropathy\n* History or presence of a respiratory disease","35 Years","55 Years",{"count":62,"type":22},40,"INTERVENTIONAL",[65],"NA","This randomized controlled trial aims to determine the effects of the diaphragmatic release technique on neck pain, cervical range of motion, and chest expansion in patients with cervical radiculopathy. Participants will be randomized to either the baseline treatment or the experimental group for five weeks.",[26],[69,70,71,72,73],"Neck Pain","Radiculopathy","Range of Motion","Diaphragm","Musculoskeletal Manipulation","2026-06-01",{"date":76,"type":43},"2026-06-05",{"date":78,"type":43},"2026-01-01",{"date":80,"type":22},"2026-08-01",{"name":82,"class":50},"Riphah International University",{"id":84,"slug":85,"hasResults":12,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":12,"sex":17,"minAge":90,"maxAge":91,"enrollmentInfo":92,"targetDuration":4,"studyType":63,"phases":94,"briefSummary":95,"conditions":96,"keywords":97,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":51},"100608884","ultrasound-guided-transcutaneous-pulsed-radiofrequency-for-cervical-radiculopathy-100608884","NCT07207356","Ultrasound Guided Transcutaneous Pulsed Radiofrequency for Cervical Radiculopathy","The Efficacy of Ultrasound Guided Transcutaneous Pulsed Radiofrequency for Cervical Radiculopathy: a Randomized, Sham-controlled, Double-blind Pilot Study","Inclusion Criteria:\n\n* Age between 20 and 75 years old.\n* Clinical diagnosis of cervical radiculopathy, defined by:\n\n  1. Presence of neck pain or paresthesia radiating to the unilateral upper extremity with radicular and dermatomal pattern;\n  2. Positive Spurling's test;\n  3. Positive cervical distraction test\n* Symptoms lasting for over 6 weeks\n* Numeric Rating Scale (NRS) for arm pain ≥ 4 out of 10\n* MRI or CT-confirmed nerve root compression, corresponding to clinical symptoms.\n* Able to provide written informed consent and comply with study procedures\n\nExclusion Criteria:\n\n* History of cervical spine surgery.\n* Motor deficit on involving limb\n* Presence of axial neck pain without radicular symptoms\n* Symptoms from shoulder, elbow, or wrist joint or other musculoskeletal co-morbidity such as rheumatologic disease or carpal tunnel syndrome\n* Evidence of serious underlying pathology (e.g., tumor, infection, fracture, or myelopathy)\n* Prior exposure to epidural steroid injection or pulsed radiofrequency therapy within the past 6 months\n* Presence of pregnancy or breastfeeding.\n* History of epilepsy or electronic devices implanted in the body\n* Active infection or skin disease at the stimulator contact site\n* Allergy to electrode patch\n* Unable to understand the study protocol or provide written","20 Years","75 Years",{"count":93,"type":22},32,[65],"Cervical radiculopathy (CR) is a painful condition caused by irritation of the cervical nerve roots, often leading to neck, shoulder, and arm pain, sometimes with numbness or weakness. These symptoms can reduce quality of life and place a burden on healthcare systems. Current treatments, such as physical therapy, cervical traction, and medication, are often not fully effective. Pulsed radiofrequency (PRF) has shown benefits for nerve-related pain, but because it requires an invasive procedure, its use is limited.\n\nTranscutaneous pulsed radiofrequency (TCPRF) is a non-invasive version of PRF. It has shown promising results in animal studies and in clinical research for knee and shoulder conditions, but has not been tested for CR. Recent improvements in ultrasound allow more precise targeting of cervical nerve roots, making ultrasound-guided TCPRF a potentially safe and accessible treatment option.\n\nThis pilot study will evaluate the efficacy and safety of ultrasound-guided TCPRF in patients with CR compared to a sham treatment. A total of 32 participants with CR lasting more than six weeks will be randomly assigned to either TCPRF or sham treatment. Both groups will receive 12 treatment sessions over four weeks, combined with a standard rehabilitation program.\n\nThe main outcome is pain intensity measured by the Numeric Rating Scale (NRS). Secondary outcomes include neck-related disability, medication use, and any side effects.",[26],[33,98,99,100],"pulsed radiofrequency","transcutaneous pulsed radiofrequency","ultrasound guided","2026-05-08",{"date":103,"type":43},"2026-05-13",{"date":105,"type":43},"2025-11-01",{"date":107,"type":22},"2027-04-30",{"name":109,"class":50},"Shin Kong Wu Ho-Su Memorial Hospital",{"id":111,"slug":112,"hasResults":12,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":117,"enrollmentInfo":118,"targetDuration":4,"studyType":63,"phases":120,"briefSummary":121,"conditions":122,"keywords":125,"overallStatus":133,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":51},"100635833","transcutaneous-auricular-vagus-nerve-stimulation-combined-with-cervical-epidural-injection-for-cervical-radiculopathy-100635833","NCT07557823","Transcutaneous Auricular Vagus Nerve Stimulation Combined With Cervical Epidural Injection for Cervical Radiculopathy","Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Combined With Cervical Epidural Injection in the Treatment of Cervical Radiculopathy: A Randomized, Double-Blind, Sham-Controlled Trial.","Inclusion Criteria:\n\n1. Age between 18 and 85 years old.\n2. Body Mass Index (BMI) between 18 and 35 kg\u002Fm².\n3. American Society of Anesthesiologists (ASA) physical status I to III.\n4. Diagnosed with cervical radiculopathy, scheduled for selective cervical epidural injection.\n5. Estimated procedure duration ≤ 1 hour.\n6. Able to understand and provide written informed consent.\n\nExclusion Criteria:\n\n1. Arrhythmia requiring treatment, severe bradycardia, or postural orthostatic tachycardia syndrome.\n2. Neuromuscular disorders or auricular dermatitis.\n3. Cervical fracture, tumor, tuberculosis, or active infection confirmed by imaging.\n4. Contraindications to vagus nerve stimulation: carotid sinus hypersensitivity, bilateral carotid artery stenosis.\n5. Severe psychiatric disorder or history of substance abuse.","85 Years",{"count":119,"type":22},80,[65],"This is a prospective, randomized, double-blinded, sham-controlled trial conducted to investigate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) combined with cervical epidural injection in the treatment of cervical radiculopathy. A total of 80 subjects will be enrolled and randomly assigned (1:1) to either the experimental group or the control group. The primary outcome measure is the proportion of subjects with a ≥50% reduction in the Numerical Rating Scale (NRS) pain score at discharge. Secondary outcomes include pain intensity, pain interference, psychological status, sleep quality, physical disability, and autonomic function measurements. Adverse events will be monitored throughout the study.",[26,123,124],"Cervical Spondylosis","Radicular Pain",[126,127,128,129,130,131,132],"taVNS","transcutaneous auricular vagus nerve stimulation","cervical epidural injection; cervical radiculopathy","pain","arm pain","pain management","neuromodulation","NOT_YET_RECRUITING","2026-04-26",{"date":136,"type":43},"2026-04-29",{"date":138,"type":22},"2026-04-10",{"date":140,"type":22},"2027-03-31",{"name":142,"class":50},"Second Affiliated Hospital, School of Medicine, Zhejiang University",{"id":144,"slug":145,"hasResults":12,"nctId":146,"briefTitle":147,"officialTitle":147,"acronym":148,"eligibilityCriteria":149,"healthyVolunteers":12,"sex":17,"minAge":150,"maxAge":151,"enrollmentInfo":152,"targetDuration":4,"studyType":63,"phases":154,"briefSummary":155,"conditions":156,"keywords":157,"overallStatus":133,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":166,"locationsCount":4},"100635809","transcutaneous-electrical-nerve-stimulation-versus-repetitive-transcranial-magnetic-stimulation-on-pain-and-functional-outcome-in-cervical-radiculopathy-100635809","NCT07557511","Transcutaneous Electrical Nerve Stimulation Versus Repetitive Transcranial Magnetic Stimulation on Pain and Functional Outcome in Cervical Radiculopathy","CR","Inclusion Criteria:\n\n* patients will be from both sexes, aged between (30 to 45) years\n* patients will be diagnosed as cervical radiculopathy unilateral upper limb pain radiating in C5,6 and C6,7 in the lateral aspect of the arm, forearm and hand for at least 3 months sensory in nature. (Sharma et al., 2025).\n* The Neck Disability Index (NDI) NDI more than 20%.\n* body mass index (BMI) was (18.5 to 29.9) Kg\u002Fm2.\n* Numeric Pain Rating Scale (NPRS) score \\> 6 y\n\nExclusion Criteria:\n\n* Patients with a history of injury to the cervical spine.\n* Patients who underwent cervicothoracic spine surgery, motor manifestations , spinal canal stenosis, bilateral symptoms, upper motor neuron impairments.\n* Use of steroids and pharmacological therapy.\n* Any congenital anomaly like cervical rib.\n* Pregnancy, oncological episodes.\n* The presence of a pacemaker, cochlear implant.\n* Epilepsy, psychotropic drug intake before admission, neurological disorders (such as stroke and plexopathies),","30 Years","45 Years",{"count":153,"type":22},50,[65],"this study will be conducted to compare between transcutaneous electrical nerve stimulation versus repetitive transcranial magnetic stimulation on pain and functional outcome in cervical radiculopathy",[26],[158,159,129,160,33],"Transcutaneous Electrical Nerve Stimulation","Repetitive Transcranial Magnetic Stimulation","functional outcome","2026-04-23",{"date":136,"type":43},{"date":164,"type":22},"2026-04-30",{"date":80,"type":22},{"name":167,"class":50},"Cairo University",{"id":169,"slug":170,"hasResults":12,"nctId":171,"briefTitle":172,"officialTitle":173,"acronym":4,"eligibilityCriteria":174,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":175,"enrollmentInfo":176,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":178,"conditions":179,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":186,"locationsCount":51},"100590757","cervical-radiculopathy-imaging-using-mrn-with-electrodiagnostic-correlation-100590757","NCT06971575","Cervical Radiculopathy Imaging Using MRN With Electrodiagnostic Correlation","Cervical Radiculopathy Imaging Using MR Neurography With Electrodiagnostic Correlation","Inclusion Criteria:\n\n* Patients presenting with symptoms compatible with acute or subacute unilateral (one-sided) cervical radiculopathy and signs of clinical weakness\n* 18-60 years old at the time of evaluation\n* Symptom onset of 2 to 12 weeks leading up to baseline visit\n* Diagnosis of unilateral cervical radiculopathy, with or without spinal cord compression, based on signs and symptoms, physical exam and supported by MRI findings of radiculopathy (as evidenced by foraminal stenosis\u002Fnarrowing) based on standard-of-care cervical spine MRI\n* Patients who have undergone or have planned electrodiagnostic testing at HSS prior to surgery\n\nExclusion Criteria:\n\n* Prior cervical surgery or instrumentation\n* Those who have had a prior episode of cervical radiculopathy\n* History of peripheral neuropathy or another acute or chronic neurodegenerative condition\n* History of stroke, cerebellar disease, or central nervous system disease\n* Contraindications to undergoing a standard MRI examination (e.g., pregnancy)\n* Patients presenting with bilateral cervical radiculopathy","60 Years",{"count":177,"type":22},20,"This project will study patients with cervical radiculopathy. We will evaluate the combined diagnostic and prognostic value of magnetic resonance neurography (MRN), electrodiagnostic (EDX) studies, and historical and physical clinical elements. Specifically, this project will explore whether these data individually or in combination correlate with response to procedural and non-procedural treatment.",[26],{"date":181,"type":43},"2026-04-27",{"date":183,"type":43},"2023-10-24",{"date":185,"type":22},"2026-10",{"name":187,"class":50},"Hospital for Special Surgery, New York",{"id":189,"slug":190,"hasResults":12,"nctId":191,"briefTitle":192,"officialTitle":193,"acronym":194,"eligibilityCriteria":195,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":196,"enrollmentInfo":197,"targetDuration":4,"studyType":63,"phases":199,"briefSummary":200,"conditions":201,"keywords":203,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":206,"lastUpdatePostDateStruct":207,"startDateStruct":209,"completionDateStruct":211,"leadSponsor":213,"locationsCount":51},"100631907","home-based-exercise-after-cervical-epidural-steroid-injection-for-cervical-radiculopathy-100631907","NCT07506785","Home-Based Exercise After Cervical Epidural Steroid Injection for Cervical Radiculopathy","Effect of a Home-Based Exercise Program After Cervical Interlaminar Epidural Steroid Injection on Clinical Outcomes in Patients With Chronic Cervical Radiculopathy: A Randomized Controlled Trial","CESI-HEP","Inclusion Criteria:\n\n* Age between 18 and 70 years.\n* Chronic cervical radicular pain lasting ≥3 months, characterized by neck pain with accompanying arm pain consistent with a cervical nerve root distribution.\n* Average pain intensity ≥4\u002F10 on the Numeric Rating Scale (NRS) over the preceding 7 days at baseline.\n* Diagnosis of chronic cervical radiculopathy due to cervical disc herniation, confirmed by clinical examination and cervical MRI findings at the corresponding level.\n* Insufficient response to conservative treatment, including physical therapy, medication, and\u002For exercise therapy.\n* Ability to provide written informed consent and comply with study procedures.\n\nExclusion Criteria:\n\n* Patients were excluded if any of the following were present:\n* Clinical signs of cervical myelopathy or progressive neurological deficit.\n* Suspicion of serious spinal pathology (e.g., infection, malignancy).\n* Contraindications to epidural steroid injection, including uncontrolled coagulopathy, anticoagulant therapy not appropriately managed, or local\u002Fsystemic infection.\n* Pregnancy.\n* Prior cervical spine surgery or cervical epidural steroid injection within the prespecified washout period.\n* Severe musculoskeletal or neurological comorbidities that could interfere with safe participation in the exercise program.\n* Discordance between clinical symptoms and imaging findings.","70 Years",{"count":198,"type":22},60,[65],"Cervical radiculopathy is a common cause of neck and arm pain resulting from compression or inflammation of a cervical nerve root. Cervical epidural steroid injection is frequently used to reduce pain and improve function in patients who do not respond to conservative treatment. However, long-term functional recovery may require additional rehabilitation strategies. This randomized controlled trial aims to investigate whether adding a standardized home-based exercise program after cervical interlaminar epidural steroid injection improves pain, disability, sleep quality, and quality of life in patients with chronic cervical radiculopathy. Participants will be randomly assigned to receive either injection alone or injection followed by an eight-week home-based exercise program.",[26,202],"Home Based Rehabilitation",[204,69,33,205],"Cervical Epidural Steroid Injection","Home based exercise","2026-03-28",{"date":208,"type":43},"2026-04-02",{"date":210,"type":43},"2026-02-01",{"date":212,"type":22},"2026-06",{"name":214,"class":50},"Necmettin Erbakan University",{"id":216,"slug":217,"hasResults":12,"nctId":218,"briefTitle":219,"officialTitle":220,"acronym":4,"eligibilityCriteria":221,"healthyVolunteers":12,"sex":17,"minAge":90,"maxAge":222,"enrollmentInfo":223,"targetDuration":4,"studyType":63,"phases":225,"briefSummary":226,"conditions":227,"keywords":228,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":231,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":238,"locationsCount":51},"100596477","mulligan-mobilization--stretching-effects-of-cervical-100596477","NCT07045974","Mulligan Mobilization & Stretching Effects of Cervical","Effects of Mulligan Mobilization and Stretching on Cervical Radiculopathy","Inclusion Criteria:\n\n* Participants falling in this category would be recruited into the study.\n\n  * Both genders\n  * Age between 20-50 years\n  * Subjects with neck pain radiating down to the arm\n  * Patients with positive findings for spurling test, Upper Limb Tension Test (ULTT), cervical distraction test and cervical rotation test towards the symptomatic side\n  * Subjects who were willing to participate in the study and willing to take treatment for cervical radiculopathy.\n\nExclusion Criteria:\n\n* Participant failing to fall in this category would be excluded of the study.\n\n  * Systemic disease potentially affecting the musculoskeletal system Patients experiencing primary shoulder or upper extremity problem of local origin\n  * Patients with any cardiovascular disorders and respiratory disorders\n  * Patients with any other pathological conditions involving cervical spine like vertebro basilar insufficiency and canal stenosis\n  * Patients having osteophytes in cervical vertebrae\n  * Patients who were undergoing treatment for neck pain with other means of physiotherapy at the time of the study\n  * Hypermobile joints of cervical vertebrae, Cervical fractures, spinal surgery or other spinal pathologies (i.e. ankylosing spondylitis, spondylolysthesis)\n  * Peripheral nerve lesions like neurotemesis and axonotemesis","50 Years",{"count":224,"type":22},30,[65],"1. To evaluate the effectiveness of mulligan mobilization and stretching exercises in reducing pain in individuals with cervical radiculopathy.\n2. To evaluate the effectiveness of mulligan mobilization and stretching exercises in reducing disability in individuals with cervical radiculopathy.\n3. To evaluate the effectiveness of mulligan mobilization and stretching exercises at improving ranges in individuals with cervical radiculopathy.",[26],[229,230,71],"Pain","Disability Level","2026-02-23",{"date":233,"type":43},"2026-02-25",{"date":235,"type":43},"2025-07-15",{"date":237,"type":22},"2026-12-30",{"name":82,"class":50},{"id":240,"slug":241,"hasResults":12,"nctId":242,"briefTitle":243,"officialTitle":244,"acronym":4,"eligibilityCriteria":245,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":60,"enrollmentInfo":246,"targetDuration":4,"studyType":63,"phases":248,"briefSummary":249,"conditions":250,"keywords":254,"overallStatus":133,"whyStopped":4,"lastUpdateSubmitDate":258,"lastUpdatePostDateStruct":259,"startDateStruct":261,"completionDateStruct":263,"leadSponsor":265,"locationsCount":51},"100626003","nerve-gliding-exercises-in-cervical-radiculopathy-100626003","NCT07429981","Nerve Gliding Exercises in Cervical Radiculopathy","Investigation of the Effectiveness of Nerve Gliding Exercises in Individuals With Cervical Radiculopathy","Inclusion Criteria:\n\n* Have been diagnosed with cervical radiculopathy by a specialist physician\n* Have disc herniation at the C5-C6, C6-C7 or C7-T1 level according to imaging (magnetic resonance imaging, MRI) findings (in the bulging or protrusion stage)\n* Have unilateral nerve root involvement\n\nExclusion Criteria:\n\n* Predominance of primary peripheral entrapment neuropathy (carpal\u002Fcubital\u002Fradial tunnel, etc.)\n* Multiple nerve root involvement\n* Progressive neurological deficit\n* History of trauma or surgery to the cervical and upper extremity region\n* Systemic disease contraindicating exercise\n* Pregnancy\n* Manual therapy, injection, or regular physiotherapy applied to the cervical region within the last 3 months\n* Cognitive\u002Fpsychiatric condition preventing compliance with the assessment protocol",{"count":247,"type":22},28,[65],"The aim of this study is to investigate the effect of nerve gliding exercises on pain, cervical range of motion, joint position sense, grip strength, functional status and quality of life in individuals with cervical radiculopathy.",[251,252,253,26],"Cervical Radiculopathy at C5 Nerve Root","Cervical Radiculopathy at C6 Nerve Root","Cervical Radiculopathy at C7 Nerve Root",[255,256,257],"Cervical radiculopathy","Neural glide","Neuromobilization","2026-02-18",{"date":260,"type":43},"2026-02-24",{"date":262,"type":22},"2026-04",{"date":264,"type":22},"2026-08",{"name":266,"class":50},"Zonguldak Bulent Ecevit University",{"id":268,"slug":269,"hasResults":12,"nctId":270,"briefTitle":271,"officialTitle":272,"acronym":4,"eligibilityCriteria":273,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":175,"enrollmentInfo":274,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":275,"conditions":276,"keywords":279,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":294,"lastUpdatePostDateStruct":295,"startDateStruct":297,"completionDateStruct":299,"leadSponsor":301,"locationsCount":51},"100493123","comparison-of-artificial-disc-implants-in-cervical-disc-arthroplasty-100493123","NCT05701059","Comparison of Artificial Disc Implants in Cervical Disc Arthroplasty","Comparison of Unconstrained and Semi-constrained Artificial Disc Implants Used in Cervical Disc Arthroplasty","Inclusion Criteria:\n\n* Patient is skeletally mature and between 18 to 60 years of age\n* Experiences cervical spondylotic myelopathy and\u002For radiculopathy typically caused by disc herniation or degenerative disc disease at a single level between C3 to C7\n* Is unresponsive to at least six weeks of non-surgical conservative care\n* Has the intention of undergoing cervical arthroplasty for their chief complaint\n* Signed informed consent form\n\nExclusion Criteria:\n\n* Patient has had prior cervical spine surgery\n* Has more than two diseased levels requiring surgery\n* Has a known allergy to a metal alloy or polyethylene\n* Is morbidly obese\n* Has active local or system infection\n* Has any circumstances or conditions such that their ability to provide informed consent comply with follow-up requirements, or provide self-assessments is compromised (eg: psychiatric disorders, chronic alcohol or substance abuse, etc.)",{"count":177,"type":22},"This study will comprehensively evaluate the outcomes and endpoints of these two different FDA-approved artificial disc implants used to treat cervical spondylotic myelopathy and\u002For radiculopathy today: Biomet Zimmer Mobi-C and Nuvasive Simplify. Both implants are structurally different with the Nuvasive Simplify implementing a three-piece design with two endplates and a semi-constrained mobile core while the Biomet Zimmer Mobi-C implements an unconstrained three piece design. Subjects will be age-matched and randomly assigned to either implant with informed consent. All subjects will undergo a variety of assessments that evaluate neck disability, quality of life, pain, physiological outcome (radiographic assessments), and neck range-of motion before and after their procedure. One baseline testing will be conducted along with three post-operation visits (three months, six months, and one year) in accordance to standard follow-up procedure. Thus, the duration of participation in the study will be approximately one and a half years.",[277,26,28,278],"Cervical Spondylosis With Myelopathy","Degenerative Disc Disease",[280,281,282,283,284,285,286,287,288,289,290,291,292,293],"cervical","spondylosis","myelopathy","radiculopathy","disc","cervical disc","artificial disc","artificial disc implantation","cervical arthroplasty","disc herniation","degenerative disc disease","ACDF","Biomet Zimmer Mobi-C","Nuvasive Simplify","2026-02-10",{"date":296,"type":43},"2026-02-13",{"date":298,"type":43},"2023-05-01",{"date":300,"type":22},"2026-12-01",{"name":302,"class":50},"University of California, Los Angeles",{"id":304,"slug":305,"hasResults":12,"nctId":306,"briefTitle":307,"officialTitle":308,"acronym":4,"eligibilityCriteria":309,"healthyVolunteers":12,"sex":17,"minAge":150,"maxAge":151,"enrollmentInfo":310,"targetDuration":4,"studyType":63,"phases":312,"briefSummary":313,"conditions":314,"keywords":4,"overallStatus":133,"whyStopped":4,"lastUpdateSubmitDate":318,"lastUpdatePostDateStruct":319,"startDateStruct":321,"completionDateStruct":322,"leadSponsor":323,"locationsCount":51},"100621158","effect-of-cervical-traction-with-neural-mobilization-on-nerve-root-functions-in-cervical-radiculopathy-patients-100621158","NCT07366983","Effect of Cervical Traction With Neural Mobilization on Nerve Root Functions in Cervical Radiculopathy Patients","Effect of Cervical Traction From Different Angles With Neural Mobilization on Nerve Root Functions in Cervical Radiculopathy Patients","Inclusion Criteria:\n\n1. The patient's age will be ranged from 30 to 45 years old for both genders.\n2. The patient's with unilateral C5-6 and C6-7 (posterior lateral disc protrusion) confirmed by T 2, axial view of magnetic resonance imaging\n3. The patient's symptoms more than 3 months and positive provocative test for cervical radiculopathy (Spurling's test, shoulder abduction test, neck distraction test, and upper limb tension test 1 (Median nerve).\n4. Sensory, reflex, and\u002F or motor changes in the upper limb\n\nExclusion Criteria:\n\n1. History of surgical procedures for pathologies giving rise to neck pain or carpal tunnel syndrome\n2. Clinical signs or symptoms of medical \"red flags\" (infection, cancer, and cardiac involvement).\n3. Patients with neck pain for signs and symptoms of serious pathology, including suspected arterial insufficiency, upper cervical ligamentous insufficiency, unexplained cranial nerve dysfunction, and fracture.\n4. Systemic diseases such as autoimmune and metabolic diseases.\n5. History of steroid injection.\n6. Complete loss of sensation along the involved nerve root.\n7. bilateral radiating upper extremity\n8. Diabetic polyneuropathy.",{"count":311,"type":22},45,[65],"This study will be conducted to examine\n\n1. The efficacy of mechanical traction from decompression angles combined with neural mobilization on the H reflex of flexor carpi radialis.\n2. The efficacy of mechanical traction from decompression angles combined with neural mobilization on ultrasonography changes.\n3. The efficacy of mechanical traction from decompression angles with neural mobilization has a Numeric Pain Rating Scale.\n4. The efficacy of mechanical traction from decompression angles combined with neural mobilization on Neck Disability Index.",[26,315,316,317],"Traction","Neural Mobilization","Nerve Root Disorder","2026-01-17",{"date":320,"type":43},"2026-01-26",{"date":210,"type":22},{"date":74,"type":22},{"name":167,"class":50},{"id":325,"slug":326,"hasResults":12,"nctId":327,"briefTitle":328,"officialTitle":329,"acronym":4,"eligibilityCriteria":330,"healthyVolunteers":12,"sex":17,"minAge":59,"maxAge":222,"enrollmentInfo":331,"targetDuration":4,"studyType":63,"phases":332,"briefSummary":333,"conditions":334,"keywords":4,"overallStatus":133,"whyStopped":4,"lastUpdateSubmitDate":335,"lastUpdatePostDateStruct":336,"startDateStruct":338,"completionDateStruct":340,"leadSponsor":342,"locationsCount":4},"100618322","combination-of-kinesio-tape-and-proprioceptive-neck-exercises-on-proprioception-in-patients-with-cervical-radiculopathy-100618322","NCT07330115","Combination of Kinesio Tape and Proprioceptive Neck Exercises on Proprioception in Patients With Cervical Radiculopathy","Combination of Kinesio Tape and Poprioceptive Neck Exercises on Proprioception in Patients With Cervical Radiculopathy","Inclusion Criteria:\n\n* Age from 35-50years (Rafiq et al. 2022).\n* BMI from 18 to 29.9 kg \u002Fm2 (Morsi et al., 2022.\n* Current continuous or intermittent pain that has persisted for more than 3 months (Persson et al., 1997, Purves et al., 1998).\n* Paresthesia or numbness along the course of the nerve (Young et al., 2009).\n* Positive response for the 4 Wainner RS et al., test's item cluster:\n\n  1. Ipsilateral cervical Spurling.\n  2. Upper Limb Tension Tests (ULTTs).\n  3. Neck Distraction.\n  4. Spurling tests range (ROM) less than 60° (Wainner et al., 2003).\n* Unilateral affection in the upper limb.\n\nExclusion Criteria:\n\n* History of surgical procedures for pathologies giving rise to neck pain or CTS (Wainner et al., 2003).\n* Clinical signs or symptoms of medical \"red flags\" or serious pathology (infection, cancer, and cardiac involvement) (George et al., 2015).\n* Any systematic disease such as rheumatism and tuberculosis, cervical myelopathy, or multiple sclerosis (Joghataei et al., 2004).\n* Systemic disease is known to cause generalized peripheral neuropathy as diabetes millitus (Wainner et al., 2003).\n* Upper Motor neuron disease such as stroke and amyotrophic lateral sclerosis (ALS) (Joghataei et al., 2004).\n* Complete loss of sensation along the involved nerve root (Moustafa \\& Diab, 2014).\n* Primary report of bilateral radiating arm pain (Wainner et al., 2003)\n* Pregnant woman (Moustafa \\& Diab, 2014).",{"count":198,"type":22},[65],"This study is conducted to investigate:\n\n1. The efficiency of combination of KT and proprioceptive exercises on neck proprioception in patients with CR.\n2. The efficiency of combination of KT and proprioceptive exercises on neck pain, neck function and neuropathic pain in patients with CR.",[26,27],"2026-01-09",{"date":337,"type":43},"2026-01-12",{"date":339,"type":22},"2026-01-20",{"date":341,"type":22},"2026-04-01",{"name":343,"class":50},"Fadia Ahmed Fawzy",{"id":345,"slug":346,"hasResults":12,"nctId":347,"briefTitle":348,"officialTitle":348,"acronym":4,"eligibilityCriteria":349,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":350,"targetDuration":4,"studyType":63,"phases":352,"briefSummary":353,"conditions":354,"keywords":356,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":360,"lastUpdatePostDateStruct":361,"startDateStruct":363,"completionDateStruct":365,"leadSponsor":367,"locationsCount":51},"100616610","investigation-of-the-effects-of-interlaminar-epidural-steroid-injection-on-upper-extremity-proprioception-in-patients-with-chronic-cervical-radiculopathy-100616610","NCT07307846","Investigation of the Effects of Interlaminar Epidural Steroid Injection on Upper Extremity Proprioception in Patients With Chronic Cervical Radiculopathy","Inclusion Criteria:\n\nParticipants must meet all of the following:\n\n* Female or male, 18-65 years of age\n* Presence of unilateral cervical radicular pain lasting at least 3 months\n* MRI of the cervical spine within the last 12 months demonstrating at least one cervical disc herniation consistent with the patient's symptoms\n* Diagnosed with chronic cervical radiculopathy based on history, physical examination, and clinical evaluation\n* Ability to read and write (literacy)\n* Willingness to participate and ability to provide written informed consent\n\nExclusion Criteria:\n\nParticipants will be excluded for any of the following:\n\n* Cervical physical therapy or cervical spinal injection performed within the past 6 months\n* Symptoms or diagnosis of upper extremity entrapment neuropathy\n* Documented vitamin B12 deficiency or vitamin D deficiency on laboratory results within the past year\n* History of cervical spine surgery or significant cervical trauma\n* Bilateral cervical radicular pain\n* Cervical spinal stenosis\n* History of upper extremity surgery or significant upper extremity trauma\n* Cognitive impairment, major psychiatric disorder, intellectual disability, or history of significant neurological disease\n* Diagnosis of polyneuropathy\n* Diagnosis of Diabetes Mellitus\n* Diagnosis of fibromyalgia\n* Current use of medications that may impair proprioception or have sedative effects (e.g., gabapentinoids, antidepressants, muscle relaxants)\n* Active local or systemic infection\n* Coagulopathy or bleeding diathesis\n* Known allergy to any components of the planned injection (triamcinolone, lidocaine, saline, contrast medium)\n* Pregnancy\n* Inability or unwillingness to provide informed consent\n* Illiteracy (unable to read or write)\n\nWithdrawal Criteria\n\n* Voluntary withdrawal of consent at any time\n* Inability or unwillingness to continue study participation for any reason\n* New medical condition or event after enrollment that renders continuation unsafe according to the investigator's judgment",{"count":351,"type":22},46,[65],"Cervical radiculopathy is a common condition caused by irritation or compression of cervical nerve roots, often leading to unilateral neuropathic pain and functional impairment. Proprioceptive deficits in the upper extremity have been demonstrated in various cervical spine disorders; however, the effect of interlaminar epidural steroid injection (ILESI) on upper extremity proprioception in patients with chronic cervical radiculopathy has not been previously examined.\n\nThis prospective interventional study aims to evaluate changes in upper extremity proprioception following unilateral ILESI in patients with cervical disc herniation-related chronic radiculopathy. A secondary aim is to investigate the relationship between proprioceptive changes and clinical outcomes such as pain, neuropathic pain, disability, grip strength, and quality of life.",[26,355,27],"Cervical Radicular Pain",[33,357,358,34,359],"cervical radicular pain","interlaminar epidural steroid injection","proprioceptive impairment","2025-12-31",{"date":362,"type":43},"2026-01-02",{"date":364,"type":22},"2026-01-05",{"date":366,"type":22},"2026-05-01",{"name":49,"class":50},{"id":369,"slug":370,"hasResults":12,"nctId":371,"briefTitle":372,"officialTitle":373,"acronym":4,"eligibilityCriteria":374,"healthyVolunteers":12,"sex":17,"minAge":150,"maxAge":151,"enrollmentInfo":375,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":376,"conditions":377,"keywords":4,"overallStatus":133,"whyStopped":4,"lastUpdateSubmitDate":378,"lastUpdatePostDateStruct":379,"startDateStruct":381,"completionDateStruct":382,"leadSponsor":384,"locationsCount":4},"100617630","correlation-between-cervical-deep-flexors-endurance-and-proprioception-function-in-cervical-radiculopathy-100617630","NCT07321119","Correlation Between Cervical Deep Flexors Endurance and Proprioception Function in Cervical Radiculopathy","Correlation Between Endurance and Proprioception Function in Cervical Radiculopathy","Inclusion Criteria:\n\n* Adults diagnosed with cervical radiculopathy based on clinical examination (± imaging confirmation).\n\nPresence of neck pain with radiating symptoms to the upper limb for at least 4 weeks.\n\nAge range 20-60 years.\n\nAbility to understand instructions and participate in cervical endurance and proprioception assessments.\n\nExclusion Criteria:\n\n* History of cervical spine surgery or acute cervical trauma.\n\nPresence of neurological disorders other than cervical radiculopathy (e.g., stroke, multiple sclerosis).\n\nVestibular disorders or conditions affecting balance and head position sense.\n\nInflammatory, rheumatologic, or severe musculoskeletal conditions involving the cervical spine.",{"count":119,"type":22},"In cervical radiculopathy, reduced endurance of the deep cervical flexor muscles is associated with impaired cervical proprioception. This relationship reflects altered sensorimotor control due to muscle dysfunction and neural compromise, emphasizing the need for deep flexor endurance training in rehabilitation.",[26],"2025-12-26",{"date":380,"type":43},"2026-01-06",{"date":78,"type":22},{"date":383,"type":22},"2026-03-01",{"name":385,"class":50},"Delta University for Science and Technology",{"id":387,"slug":388,"hasResults":12,"nctId":389,"briefTitle":390,"officialTitle":390,"acronym":4,"eligibilityCriteria":391,"healthyVolunteers":12,"sex":17,"minAge":392,"maxAge":222,"enrollmentInfo":393,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":395,"conditions":396,"keywords":4,"overallStatus":133,"whyStopped":4,"lastUpdateSubmitDate":397,"lastUpdatePostDateStruct":398,"startDateStruct":400,"completionDateStruct":402,"leadSponsor":404,"locationsCount":51},"100618021","gait-asymmetry-and-its-relationship-with-neck-pain-and-muscles-strength-in-patients-with-cervical-radiculopathy-100618021","NCT07326202","Gait Asymmetry And Its Relationship With Neck Pain And Muscles Strength In Patients With Cervical Radiculopathy","Inclusion Criteria:\n\n* Patients with unilateral cervical radiculopathy at level of C5-C6 and C6-C7 confirmed by MRI.\n* Patient's age will be ranged from 40 to 50 years.\n* Patients with chronic symptoms \\> 3 months.\n* Patients with decreased strength in cervical or upper limb muscles.\n* Ability to walk independently without assistive devices.\n* Patients with normal body mass index (BMI) (\\\u003C 30kg\u002Fm²) .\n\nExclusion Criteria:\n\n* Bilateral cervical radiculopathy.\n* History of cervical spine surgery or instability.\n* Diagnosed with myelopathy, canal stenosis, or severe disc protrusion.\n* History of vestibular dysfunction, stroke, or severe cognitive impairment.\n* Any Lower limb dysfunction affecting walking.\n* Peripheral neuropathy or uncontrolled diabetes.\n* Psychiatric diseases\n* Pregnancy.","40 Years",{"count":394,"type":22},61,"This study will be conducted to:\n\n* Investigate the relationship between neck pain severity and bilateral gait symmetry in patients with cervical radiculopathy.\n* Investigate the relationship between deep neck flexors strength and gait symmetry in patients with cervical radiculopathy.\n* Investigate the relationship between upper limb muscles strength and bilateral gait symmetry in patients with cervical radiculopathy.\n* Determine factors predicting bilateral gait asymmetry in patients with cervical radiculopathy.",[26],"2025-12-24",{"date":399,"type":43},"2026-01-08",{"date":401,"type":22},"2025-12-30",{"date":403,"type":22},"2026-03-30",{"name":167,"class":50},{"id":406,"slug":407,"hasResults":12,"nctId":408,"briefTitle":409,"officialTitle":410,"acronym":4,"eligibilityCriteria":411,"healthyVolunteers":12,"sex":17,"minAge":150,"maxAge":151,"enrollmentInfo":412,"targetDuration":4,"studyType":63,"phases":413,"briefSummary":414,"conditions":415,"keywords":416,"overallStatus":133,"whyStopped":4,"lastUpdateSubmitDate":418,"lastUpdatePostDateStruct":419,"startDateStruct":421,"completionDateStruct":422,"leadSponsor":424,"locationsCount":51},"100615207","effect-of-tecar-on-cervical-radiculopathy-100615207","NCT07289607","Effect of TECAR on Cervical Radiculopathy","Effect of TECAR Therapy on Proprioception Function in Patients With Cervical Radiculopathy","Inclusion Criteria:\n\n* • Diagnosed cervical radiculopathy confirmed by clinical and radiological findings\n\n  * Age 30-40 years\n  * Pain duration \\> 4 weeks\n\nExclusion Criteria:\n\n* • Cervical fracture or surgery\n\n  * Vestibular disorders\n  * Rheumatologic or neurological diseases\n  * Cognitive impairment or pregnancy",{"count":119,"type":22},[65],"Cervical radiculopathy is characterized by pain, sensory disturbances, and impaired neuromuscular control due to nerve root compression. Proprioception dysfunction is often an overlooked component of this condition and can affect balance, posture, and motor control.\n\nTECAR (Transfer of Energy Capacitive and Resistive) therapy is a form of deep heat electrotherapy known to improve tissue perfusion and neuromuscular function. Although TECAR is widely used for pain relief and mobility, its role in improving proprioception remains under-investigated, especially in cervical conditions. This study aims to bridge this gap by assessing proprioceptive outcomes in patients with cervical radiculopathy receiving TECAR therapy.",[26],[417],"TECAR , radiculopathy , Proprioception","2025-12-17",{"date":420,"type":43},"2025-12-18",{"date":78,"type":22},{"date":423,"type":22},"2026-04-05",{"name":385,"class":50},{"id":426,"slug":427,"hasResults":12,"nctId":428,"briefTitle":429,"officialTitle":430,"acronym":4,"eligibilityCriteria":431,"healthyVolunteers":12,"sex":17,"minAge":150,"maxAge":60,"enrollmentInfo":432,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":434,"conditions":435,"keywords":436,"overallStatus":133,"whyStopped":4,"lastUpdateSubmitDate":442,"lastUpdatePostDateStruct":443,"startDateStruct":445,"completionDateStruct":447,"leadSponsor":449,"locationsCount":51},"100611400","relationship-between-craniovertebral-angle-lumbar-proprioception-and-trunk-muscle-strength-in-cervical-radiculopathy-100611400","NCT07240090","Relationship Between Craniovertebral Angle, Lumbar Proprioception, and Trunk Muscle Strength in Cervical Radiculopathy","Relation of Craniovertebral Angle With Lumbar Proprioception and Trunk Muscles Strength in Patients With Cervical Radiculopathy","Inclusion Criteria:\n\n* Patients with cervical radiculopathy with ≥3 months history of neck pain radiating to only one upper extremity (unilateral)\n* Patients with forward head posture and craniovertebral angle \\\u003C50°\n* Age between 30 and 55 years\n* Body mass index (BMI) between 18 and 29.9 kg\u002Fm²\n\nExclusion Criteria:\n\n* Cervical myelopathy\n* Acute cervical radiculopathy\n* Neck pain without radiculopathy\n* Diabetic neuropathy\n* Previous cervical surgery\n* Cervical trauma\n* Entrapment neuropathies in the upper limbs\n* Rheumatoid arthritis\n* Tumors or infections involving the cervical or lumbar spine\n* Acute or chronic lumbar radiculopathy\n* Vertebral fractures\n* Lumbar spinal stenosis\n* Cauda equina syndrome\n* Previous lumbar surgery\n* Lumbar spondylolisthesis",{"count":433,"type":22},64,"The study aimed to\n\n* Investigate the relation of cranio-vertebral angle with lumbar proprioception in patients with cervical radiculopathy.\n* Investigate the relation of cranio-vertebral angle with trunk muscles strength in patients with cervical radiculopathy. Cervical radiculopathy is a condition that causes neck pain radiating to the arm due to nerve root compression. The study seeks to explore whether posture and trunk control are affected in these patients. Participants will be assessed for craniovertebral angle, lumbar proprioception, and trunk muscle strength using standardized physical therapy evaluation methods. The findings may help in understanding postural and neuromuscular changes associated with cervical radiculopathy and improve rehabilitation programs",[26],[437,438,439,26,440,441],"Craniovertebral Angle","Lumbar Proprioception","Trunk Muscle Strength","Forward Head Posture","Low Back Pain","2025-11-19",{"date":444,"type":43},"2025-11-20",{"date":446,"type":22},"2025-11-18",{"date":448,"type":22},"2026-01-15",{"name":450,"class":50},"Basma Ashraf Ali Mohamed",{"id":452,"slug":453,"hasResults":12,"nctId":454,"briefTitle":455,"officialTitle":456,"acronym":457,"eligibilityCriteria":458,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":459,"targetDuration":4,"studyType":63,"phases":460,"briefSummary":461,"conditions":462,"keywords":464,"overallStatus":133,"whyStopped":4,"lastUpdateSubmitDate":446,"lastUpdatePostDateStruct":481,"startDateStruct":483,"completionDateStruct":485,"leadSponsor":487,"locationsCount":4},"100612081","contralateral-neural-tissue-mobilization-for-cervical-radiculopathy-100612081","NCT07248943","Contralateral Neural Tissue Mobilization for Cervical Radiculopathy","Contralateral Neural Tissue Mobilization for Cervical Radiculopathy: An Exploratory Study","NTM","Inclusion Criteria:\n\n* Age 18 years or older Presence of unilateral upper-extremity pain in a dermatomal distribution consistent with cervical radiculopathy (with or without neck pain)\n* Able to read and understand English\n* Willing and able to provide written informed consent\n* New patient to the clinic or established patient who meets inclusion criteria and has not previously received neural tissue mobilization as part of treatment\n\nExclusion Criteria:\n\n* Bilateral upper-extremity pain\n* Upper-extremity pain that is non-dermatomal in distribution\n* Presence of contraindications or precautions preventing use of the contralateral limb for neural tissue mobilization (e.g., injury, allodynia, recent surgery, postsurgical complications)\n* Not willing to participate in the study",{"count":62,"type":22},[65],"Cervical radiculopathy (CR) is a common form of peripheral neuropathic pain characterized by neck and upper extremity symptoms in a dermatomal distribution. Neural tissue mobilization (NTM) is an intervention shown to provide benefit for neuropathic pain presentations; however, some patients are unable to tolerate direct treatment of the symptomatic limb due to allodynia, hyperalgesia, or fear of movement. Early evidence from lower-extremity research suggests that contralateral NTM may produce therapeutic effects similar to ipsilateral treatment, but this approach has not been investigated in individuals with upper-extremity symptoms.\n\nThis exploratory case series aims to examine the immediate effects of contralateral NTM in adults presenting to outpatient physical therapy with CR. Participants will undergo pre- and post-treatment assessments of pain intensity, disability, fear-avoidance beliefs, pain distribution, and neurodynamic mechanosensitivity. Findings will provide preliminary evidence regarding whether contralateral NTM may serve as a viable treatment option when direct symptomatic limb treatment is not tolerated.",[26,229,463,124],"Neuropathic Pain",[26,463,465,466,124,467,468,469,470,471,472,473,474,475,476,477,478,479,480],"Peripheral Neuropathic Pain","Upper Extremity Pain","Cervical Spine Disorders","Nerve Root Compression","Neural Tissue Mobilization","Neurodynamic Mobilization","Neurodynamics","Contralateral Treatment","Median Nerve Mobilization","Upper Limb Neurodynamic Test (ULNT1a)","Physical Therapy","Musculoskeletal Pain","Pain Phenotyping","Manual Therapy","Rehabilitation","Mechanosensitivity",{"date":482,"type":43},"2025-11-25",{"date":484,"type":22},"2025-12",{"date":486,"type":22},"2026-09",{"name":488,"class":50},"Evidence In Motion",{"id":490,"slug":491,"hasResults":12,"nctId":492,"briefTitle":493,"officialTitle":494,"acronym":4,"eligibilityCriteria":495,"healthyVolunteers":12,"sex":17,"minAge":496,"maxAge":497,"enrollmentInfo":498,"targetDuration":4,"studyType":63,"phases":499,"briefSummary":500,"conditions":501,"keywords":502,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":506,"lastUpdatePostDateStruct":507,"startDateStruct":509,"completionDateStruct":511,"leadSponsor":513,"locationsCount":51},"100523945","myo-electrical-and-nerve-root-function-response-to-focused-extracorpeal-shock-wave-in-cervical-radiculopathy-100523945","NCT06102304","Myo-Electrical and Nerve Root Function Response to Focused Extracorpeal Shock Wave in Cervical Radiculopathy","Effect of Focused Focused Extracorpeal Shock Wave on the Myo-Electrical and Nerve Root Function in Patients With Cervical Radiculopathy","Inclusion Criteria:\n\n1. All patients suffer from unilateral discogenic cervical radiculopathy of lower cervical spine(C5-C6 and\u002F or C6-C7) as confirmed with MRI.\n2. All patients suffer from pain and tenderness on active trigger points of the upper trapezius .\n3. Age ranging from 36 to 46 years old.\n4. Duration of symptoms more than 3 months to avoid acute stage of inflammation.\n5. Side to side amplitude differences of 50% or more in DSSEPs measurement (Naguszewski et al.,2001)\n\nExclusion Criteria:\n\n1. Posterior osteophytes\n2. Spinal canal stenosis\n3. Rheumatoid arthritis\n4. Vestibular insufficiency\n5. Osteoporosis\n6. Any signs or symptoms of myelopathy\n7. Any abnormalities of deep sensation\n8. Associated pathologies of upper cervical region or the upper limb that may cause overlapping with clinical findings as referred pain from costotransverse joint, rotator cuff tendonitis, cervical rib syndrome and entrapment neuropathy.","36 Years","46 Years",{"count":119,"type":22},[65],"BACKGROUND: Upper limb nerve root dysfunction with increased active myofascial trigger point in upper trapezius is common problem in patients with cervical radiculopathy.\n\nThe purpose of this study was to evaluate the effect of Extracorpeal shock wave on the myo-electric and nerve function responses in patients with cervical radiculopathy.",[26],[26,503,504,505],"Nerve root Dysfunction","Trigger points","Focused Extracorpeal Shock Wave","2025-10-02",{"date":508,"type":43},"2025-10-03",{"date":510,"type":43},"2025-04-06",{"date":512,"type":22},"2026-01-18",{"name":167,"class":50},{"id":515,"slug":516,"hasResults":12,"nctId":517,"briefTitle":518,"officialTitle":519,"acronym":4,"eligibilityCriteria":520,"healthyVolunteers":12,"sex":17,"minAge":150,"maxAge":222,"enrollmentInfo":521,"targetDuration":4,"studyType":63,"phases":523,"briefSummary":524,"conditions":525,"keywords":526,"overallStatus":133,"whyStopped":4,"lastUpdateSubmitDate":529,"lastUpdatePostDateStruct":530,"startDateStruct":532,"completionDateStruct":534,"leadSponsor":536,"locationsCount":51},"100597763","median-nerve-flossing-technique-in-patients-with-cervical-radiculopathy-100597763","NCT07062718","Median Nerve Flossing Technique in Patients With Cervical Radiculopathy","Effects of Median Nerve Flossing Technique on Pain,Range of Motion and Disability in Patients With Cervical Radiculopathy","Inclusion Criteria:• Both male and female gender were included\n\n* Participants with 30 to 50 years of age group were taken in this study (Gore et al., 2020)\n* Patients with positive Spurling test ,cervical distraction ,cervical rotation test were included\n* Participants with positive Upper limb neural tension test for median nerve were taken into consideration\n* Patients who are having radicular symptoms and pain for more than 3 months were included\n\nExclusion Criteria:\n\n* Systematic disorders affecting musculoskeletal disorders e.g. Ankylosing spondylitis,rheumatic arthritis etc.\n* Patient with primary shoulder or upper limb pain origin\n* Patients with severe malignancy,COPD ,isch",{"count":522,"type":22},38,[65],"Cervical radiculopathy is a condition of cervical spinal nerve roots which occurs as a result of compression and inflammatory pathology from a space occupying lesion. Nerve flossing technique is a quick mobilization of the strained nerves which will reduce pain .This study aim to determine the effects of nerve flossing technique on pain, range of motion and disability in patients with cervical radiculopathy.",[26],[129,527,528],"range of motion","disability","2025-07-03",{"date":531,"type":43},"2025-07-14",{"date":533,"type":22},"2025-07-25",{"date":535,"type":22},"2025-10-20",{"name":82,"class":50},{"id":538,"slug":539,"hasResults":12,"nctId":540,"briefTitle":541,"officialTitle":541,"acronym":4,"eligibilityCriteria":542,"healthyVolunteers":12,"sex":17,"minAge":392,"maxAge":60,"enrollmentInfo":543,"targetDuration":4,"studyType":63,"phases":545,"briefSummary":546,"conditions":547,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":548,"lastUpdatePostDateStruct":549,"startDateStruct":551,"completionDateStruct":553,"leadSponsor":555,"locationsCount":51},"100577810","effect-of-kinetic-control-retraining-on-neck-proprioception-and-functional-outcome-in-patients-with-cervical-radiculopathy-100577810","NCT06803134","Effect of Kinetic Control Retraining on Neck Proprioception and Functional Outcome in Patients With Cervical Radiculopathy","Inclusion Criteria:\n\n* Forty Four patients suffering from chronic cervical unilateral radiculopathy (symptomatic duration) (3 months to 1year).\n* Their age ranges 40-55 years, from both sexes.\n* Body mass index (BMI) of less than 30 Kg\u002Fm2\n* Cervical spondylosis (at the levels of C5-C6\u002FC6-C7 confirmed by cervical MRI)..\n\nExclusion Criteria:\n\n* Cervical myelopathy with evidence of pyramidal, posterior column, and or spinothalamic tract lesions.\n* Patients with decreased range of motion of cervical spine secondary to congenital anomalies, musculature contracture, or bony block.\n* Previous cervical or shoulder surgery or trauma.\n* Cervical instability caused by structural problem (e.g. ligament tear or spondylolithesis.\n* Psychological problems interfering with the patient understanding of the orders, or patients who did not have direction preference.\n* Vertebro-basilar artery insufficiency, diabetic neuropathy.\n* Comorbidities that impact physical activity (e.g., cerebrovascular accidents, severe heart disease). - Double crush syndrome and thoracic outlet syndrome.",{"count":544,"type":22},44,[65],"The aim of this study is to investigate the effect of kinetic control retraining on neck proprioception and functional outcome in patients with cervical radiculopathy.",[26],"2025-04-26",{"date":550,"type":43},"2025-04-30",{"date":552,"type":43},"2025-02-01",{"date":554,"type":22},"2025-06-15",{"name":167,"class":50},{"id":557,"slug":558,"hasResults":12,"nctId":559,"briefTitle":560,"officialTitle":561,"acronym":4,"eligibilityCriteria":562,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":563,"enrollmentInfo":564,"targetDuration":4,"studyType":63,"phases":566,"briefSummary":567,"conditions":568,"keywords":570,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":573,"lastUpdatePostDateStruct":574,"startDateStruct":576,"completionDateStruct":578,"leadSponsor":580,"locationsCount":51},"100521420","predictors-of-response-to-manual-physiotherapy-using-somatosensory-profiles-in-patients-with-cervicobrachial-pain-100521420","NCT06069362","Predictors of Response to Manual Physiotherapy Using Somatosensory Profiles in Patients With Cervicobrachial Pain","Prediction of Response to Manual Physiotherapy Using Somatosensory Profiles in Patients With Cervicobrachial Pain","Inclusion Criteria:\n\n* Subjects with unilateral cervicobrachial pain\n\nExclusion Criteria:\n\n* Signs of severe disease, cervical myelopathy, tumour, rheumatic diseases or a neurological pathology of central origin.\n* Cervicobrachial pain of traumatic origin or as a result of whiplash.\n* Previous surgical intervention of the cervical spine.","80 Years",{"count":565,"type":22},91,[65],"The goal of this clinical trial is to investigate about the characteristics that predict response to physiotherapy treatment in patients with nerve related neck arm pain. The main question to answer is whether there is a subgroup that responds better to physiotherapy treatment.\n\nParticipants will be assessed for clinical and neurophysiological characteristics prior to treatment. Afterwards they will receive 6 sessions of manual physiotherapy treatment along with home nerve gliding exercises once a week. Baseline measurements will be taken again after treatment to know if there have been any changes.",[355,26,569],"Cervical Pain",[571,572],"Cervicobrachial pain","Nerve related neck arm pain","2025-03-25",{"date":575,"type":43},"2025-03-26",{"date":577,"type":43},"2023-04-20",{"date":579,"type":22},"2025-07-20",{"name":581,"class":50},"University of Deusto",{"id":583,"slug":584,"hasResults":12,"nctId":585,"briefTitle":586,"officialTitle":586,"acronym":4,"eligibilityCriteria":587,"healthyVolunteers":12,"sex":17,"minAge":392,"maxAge":60,"enrollmentInfo":588,"targetDuration":4,"studyType":63,"phases":589,"briefSummary":590,"conditions":591,"keywords":4,"overallStatus":133,"whyStopped":4,"lastUpdateSubmitDate":592,"lastUpdatePostDateStruct":593,"startDateStruct":595,"completionDateStruct":597,"leadSponsor":599,"locationsCount":51},"100572343","effect-of-kinetic-control-training-on-flexion-relaxation-phenomenon-and-craniovertebral-angle-in-cervical-radiculopathy-patients-100572343","NCT06732037","Effect of Kinetic Control Training on Flexion Relaxation Phenomenon and Craniovertebral Angle in Cervical Radiculopathy Patients","Inclusion Criteria:\n\n1. Patients will be referred from neurologist with the diagnosis cervical spondylosis.\n2. Patients will be included if they have unilateral radiculopathy due to spondylotic changes of the lower cervical spine (C5-C6 and C6-C7).\n3. Duration of symptoms is more than three months to avoid acute stage of inflammation.\n4. Patient's age ranged from 40 to 55 years.\n5. Patients from both sexes.\n6. Body mass index of all patients is ranged from 25-30 kg\u002Fm2.\n7. Patients will be screened prior to inclusion by measuring the craniovertebral angle, if the angle was less than 50, then a participant will be referred to the study\n\nExclusion Criteria:\n\n1. Spinal canal stenosis.\n2. Rheumatoid arthritis.\n3. Vertebrobasilar insufficiency.\n4. Spinal instability due to structural cause e.g., spondylolisthesis.\n5. Systemic disease (cardiovascular, infectious and\u002For metabolic disease that could interrupt exercises).\n6. Spinal tumors.",{"count":198,"type":22},[65],"The purpose of the study is to determine the effect of kinetic control training on flexion relaxation phenomenon and craniovertebral angle in patients with cervical radiculopathy.",[26],"2024-12-19",{"date":594,"type":43},"2024-12-24",{"date":596,"type":22},"2024-12-15",{"date":598,"type":22},"2025-02-22",{"name":167,"class":50},{"id":601,"slug":602,"hasResults":12,"nctId":603,"briefTitle":604,"officialTitle":605,"acronym":4,"eligibilityCriteria":606,"healthyVolunteers":12,"sex":17,"minAge":59,"maxAge":222,"enrollmentInfo":607,"targetDuration":4,"studyType":63,"phases":609,"briefSummary":610,"conditions":611,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":612,"lastUpdatePostDateStruct":613,"startDateStruct":615,"completionDateStruct":617,"leadSponsor":618,"locationsCount":51},"100569520","high-tone-power-therapy-on-neck-pain-and-proprioception-in-cervical-radiculopathy-100569520","NCT06695312","High Tone Power Therapy on Neck Pain and Proprioception in Cervical Radiculopathy","Effect of High Tone Power Therapy on Neck Pain and Proprioception in Cervical Radiculopathy Patients","Inclusion Criteria:\n\n* Their ages range from 35 to 50 years.\n* Both sex\n* With mild to moderate cervical disability according to the neck disability index\n* Unilateral cervical radiculopathy for more than 6 months.\n* Cervical radiculopathy due to disc prolapse (C5-C6) (C6-C7) mild to moderate or disc prolapse according to magnetic resonance image (MRI).\n* Normal body mass index (18.5 - 24.99Kg\u002Fm2).\n\nExclusion Criteria:\n\n* Any other musculoskeletal disorders of the spine or upper extremity\n* Patients with any other Neurological deficits, psychiatric disease Cervical myelopathy, Cognitive problems, vertebral fractures and previous history of spine or cervical surgery.\n* Neck pain with vertigo or with bilateral upper limbs referred pain.\n* Clinical instability, recent trauma and vertebrobasilar insufficiency.\n* Structural abnormalities of the spine, osteoporosis, and spasmodic torticollis.\n* Inflammatory or other specific disorders of spina such as ankylosing spondylitis and rheumatoid arthritis",{"count":608,"type":22},42,[65],"To investigate the Effect of High Tone Power Therapy on Neck Pain and Proprioception in Cervical Radiculopathy Patients.",[26],"2024-11-24",{"date":614,"type":43},"2024-11-27",{"date":616,"type":43},"2024-09-15",{"date":596,"type":22},{"name":619,"class":50},"October 6 University",{"id":621,"slug":622,"hasResults":12,"nctId":623,"briefTitle":624,"officialTitle":625,"acronym":4,"eligibilityCriteria":626,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":91,"enrollmentInfo":627,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":629,"conditions":630,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":631,"lastUpdatePostDateStruct":632,"startDateStruct":634,"completionDateStruct":636,"leadSponsor":637,"locationsCount":640},"100463122","functioning-in-individuals-with-cervical-radiculopathy-after-posterior-cervical-decompression-100463122","NCT05310578","Functioning in Individuals with Cervical Radiculopathy After Posterior Cervical Decompression","Functioning in Individuals with Cervical Radiculopathy After Posterior Cervical Decompression: a Prospective Multicenter Observational Study with a 2 Year Follow-up.","Inclusion Criteria:\n\n* Cervical radiculopathy, confirmed by MRI images (or alternative neuroradiological imaging if MRI contraindicated) compatible with clinical findings of nerve root compression (neurological examination performed by a neurosurgeon\u002Forthopedic surgeon)\n* Posterior cervical decompression as foraminotomy with our without laminectomy\n* At least 3 months of persistent arm pain\n* Age 18-75 years\n\nExclusion Criteria:\n\n* Nurick score 2 or more (to exclude individuals with moderate to high myelopathy)\n* Previous surgery of cervical spine\n* Previous fracture or dislocation of the cervical spine\n* Malignancy or benign spinal tumor (eg, neuromas)\n* Spinal infection\n* Previous spondylodiscitis\n* Servere mental disorder\n* Known alcohol or drug abuse\n* Lack of ability to write\u002Fcomprehend\u002Fexpress oneself in Swedish",{"count":628,"type":22},154,"Compression on structures, as spinal nerves, in the cervical spine can cause cervical radiculopathy which leads to pain, disability, and reduced quality of life for the affected individual. Cervical foraminotomy with our without laminectomy are common posterior decompression surgical techniques for treating cervical radiculopathy. There is a lack of knowledge regarding function in patients with cervical radiculopathy after posterior cervical decompression.\n\nThe aim with this study is to study pain, function, psychosocial factors, and health related quality of life after posterior cervical decompression in patients with cervical radiculopathy.\n\nThis is a prospective multicenter longitudinal observational cohort study with follow-up at three, 12- and 24 months postoperative. A total of 154 individuals scheduled to undergo foraminotomy with our without laminectomy due to cervical radiculopathy will be included. Primary outcome is neck-specific function measured with the Neck Disability Index. Data will be collected preoperatively and at three, 12 and 24 months with electronic questionnaire.",[26],"2024-11-21",{"date":633,"type":43},"2024-11-25",{"date":635,"type":43},"2022-08-22",{"date":360,"type":22},{"name":638,"class":639},"Linkoeping University","OTHER_GOV",3]