[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cervical-ripening\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cervical-ripening":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,48,70,100,126,154,176,206],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100624833","safety-and-usability-of-the-inga-catheter-for-labor-induction-inga-mdp-100624833",false,"NCT07414771","Safety and Usability of the Inga Catheter for Labor Induction (INGA-MDP)","A Medical Device Pilot Study to Evaluate the Safety and Usability of the Inga Catheter in Labor Induction","INGA-MDP","Inclusion Criteria:\n\n* Pregnant women aged ≥18 and ≤56 years\n* An unripe cervix, ≤6 points according to the Bishop assessment (0-10 point scale)\n* Planned induction of labor by mechanical balloon catheter method\n* Examples of diagnoses as the basis for labor induction:\n\n  * Post-term pregnancy (≥41 weeks of gestation)\n  * Maternal request for labor induction\n  * Gestational diabetes\n  * Preeclampsia (with blood pressure \\\u003C150\u002F100)\n  * Well-controlled hypertension\n  * Cholestasis of pregnancy\n  * Humanitarian or psychosocial reasons\n* Gestational age at the time of the study ≥ 37 weeks (gestational age confirmed by ultrasound before the 21st week of pregnancy)\n* Singleton pregnancy\n* Cephalic presentation\n* The subject understands the study information and signs the consent form\n\nExclusion Criteria:\n\n* Preterm induction of labor (\\\u003C37 weeks of gestation)\n* Pathological CTG at inclusion\n* Spontaneous rupture of membranes at inclusion\n* Clinically significant vaginal bleeding with need of hospitalization in the third trimester\n* Clinically active vaginal or uterine infection\n* Maternal HIV, hepatitis C, or hepatitis B\n* Uterine scar (including previous cesarean section)\n* Condition of the fetus or mother requiring immediate delivery\n* Presence of eclampsia\n* Severe Pre-eclampsia (Blood pressure ≥160\u002F110 and any of the following: low platelet count (\\\u003C100 × 10 9\u002FL), HELLP, progressive renal insufficiency, pulmonary edema)\n* Severe fetal growth restriction (FGR, fetal growth \\\u003C -2 SD)\n* Estimated fetal weight ≥ 2SD or ≥ 95th percentile\n* Breech or transverse fetal position\n* Multiple pregnancy\n* Vasa previa or placenta previa\n* Umbilical cord prolapse\n* Maternal refusal to participate in the study and\u002For insufficient language skills to understand the study information and\u002For consent form","FEMALE","18 Years","56 Years",{"count":21,"type":22},45,"ESTIMATED","INTERVENTIONAL",[25],"NA","The goal of this clinical study is to evaluate a new mechanical balloon catheter (INGA) used to prepare the cervix for labor induction in pregnant women at term.\n\nThe study aims to assess the safety, usability, and performance of the INGA catheter when used for cervical ripening before labor. Researchers will also collect feedback from healthcare professionals and participants about the use of the device.\n\nParticipants are pregnant women at term with a single baby in a head-down position who meet the study eligibility criteria.\n\nParticipants will:\n\n* have the INGA balloon catheter inserted as part of labor induction,\n* receive standard clinical care according to hospital practice,\n* provide information about their experience and outcomes related to the device.\n\nThe results of this study will help determine whether the INGA catheter is safe and suitable for use in cervical ripening during labor induction.",[28,29,30],"Induction of Labor","Cervical Ripening","Cervical Ripening and Induction of Labor",[32,33,34],"Cervical ripening","Balloon catheter","Induction of labor","NOT_YET_RECRUITING","2026-05-22",{"date":38,"type":39},"2026-05-26","ACTUAL",{"date":41,"type":22},"2026-05",{"date":43,"type":22},"2027-03-31",{"name":45,"class":46},"Aalto University","OTHER",3,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":67,"leadSponsor":69,"locationsCount":4},"100609466","open-randomized-feasibility-trial-on-the-safety-and-performance-of-the-inga-catheter-for-labor-induction-100609466","NCT07214948","Open, Randomized Feasibility Trial on the Safety and Performance of the INGA Catheter for Labor Induction","An Open, Parallel-group, Randomized, Early Feasibility Trial to Evaluate the Initial Safety and Performance of the INGA Catheter in Labor Induction","INGA-RCT","Inclusion Criteria:\n\n* Pregnant women aged ≥18 and ≤56 years\n* An unripe cervix, ≤6 points according to the Bishop score assessment (0-10-point scale)\n* Planned induction of labor by balloon catheter method\n* Gestational age at the time of the study ≥ 37 weeks (gestational age confirmed by ultrasound before the 21st week of pregnancy)\n* Singleton pregnancy\n* Cephalic presentation\n* The subject understands the study information and signs the informed consent\n\nExclusion Criteria:\n\n* Preterm induction of labor (\\\u003C37 weeks of gestation)\n* Abnormal Cardiotocography (CTG) at inclusion\n* Spontaneous rupture of membranes at inclusion\n* Clinically significant vaginal bleeding with a need of hospitalization in the third trimester\n* Clinical active vaginal or uterine infection\n* Maternal Human Immunodeficiency Virus (HIV), hepatitis C, or hepatitis B\n* Uterine scar (including previous cesarean section)\n* Condition requiring immediate delivery of the fetus or mother\n* Presence of eclampsia\n* Severe Preeclampsia \\[Blood pressure (BP)≥ 160\u002F110 and any of the following: thrombocytopenia with platelet count \\\u003C100 × 10e9\u002FL, HELLP- syndrome ( Hemolysis, Elevated Liver enzymes and Low Platelets), progressive renal insufficiency, pulmonary edema \\]\n* Severe fetal growth restriction (Fetal Growth Restriction (FGR) fetal growth \\\u003C-2 SD\u002F\\\u003C10th percentile)\n* Estimated fetal weight ≥ 2 Standard Deviation \u002F≥ 95th percentile\n* Reduced amniotic fluid volume (deepest vertical pocket \\\u003C30 mill meter)\n* Breech or transverse fetal position\n* Multiple pregnancy\n* Vasa previa or placenta previa\n* Umbilical cord prolapses\n* Bishop score ≥6 on cervical assessment prior to labor induction\n* Receiving epidural anesthesia prior to catheter insertion\n* Refusal to participate in the study and\u002For insufficient language skills to understand the study information and\u002For consent form",{"count":57,"type":22},40,[25],"This study investigates the safety and usability of the new INGA catheter for labor induction.\n\nLabor induction is common, with about one in three births being induced. In this study, the INGA catheter will be compared to a currently used method. The INGA catheter is a single-balloon device that works similarly to a Foley catheter but is made from different materials. Feedback will be collected from both healthcare professionals and participating women.",[61,29,30],"Induction of Birth",[34,63,32],"Balloon Catheter",{"date":65,"type":39},"2026-05-27",{"date":41,"type":22},{"date":68,"type":22},"2026-10-30",{"name":45,"class":46},{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":17,"minAge":18,"maxAge":79,"enrollmentInfo":80,"targetDuration":4,"studyType":23,"phases":82,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":99},"100561521","membrane-stripping-for-cervical-ripening-100561521","NCT06591247","Membrane Stripping for Cervical Ripening","Evaluation of Stripping for Cervical Ripening - A Randomized Controlled Study","Stripping","Inclusion Criteria:\n\n* Patients aged 18 and above\n* Patients with a cervical dilation of at least 1 cm\n* Full-term pregnancy\n* Cephalic presentation\n* No contraindication to vaginal delivery\n\nExclusion Criteria:\n\n* Patients with rupture of membranes\n* Patients who do not require cervical ripening and proceed directly to the delivery room for induction with oxytocin\n* Patients for whom the use of a double-balloon catheter\u002FPGE2 is contraindicated\n* Twin pregnancies\n* Pregnancies with macrosomic fetuses where vaginal delivery is contraindicated\n* Patients with maternal or fetal pathologies that do not allow for vaginal delivery due to concerns about fetal or maternal distress",true,"50 Years",{"count":81,"type":22},400,[25],"The goal of this interventional study is to evaluate the effectiveness of membrane stripping in cervical ripening compared to double balloon catheter induction.\n\nThe study population consists of women undergoing labor induction.\n\nThe main questions it aims to answer are:\n\n1. Is membrane stripping as effective as double balloon catheter induction in cervical ripening?\n2. What is the influence of membrane stripping on the time required for cervical ripening, delivery duration, and maternal and fetal outcomes compared to balloon induction.",[85,29,86,87,88,61],"Labor, Induced","Balloon Induction","Membrane Stripping","Pregnancy Related","RECRUITING","2026-04-10",{"date":92,"type":39},"2026-04-15",{"date":94,"type":39},"2024-08-07",{"date":96,"type":22},"2027-12-31",{"name":98,"class":46},"Meir Medical Center",1,{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":108,"targetDuration":4,"studyType":23,"phases":110,"briefSummary":111,"conditions":112,"keywords":114,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":4},"100626180","evaluation-of-the-inga-sensor-system-for-fetal-and-uterine-monitoring-during-cervical-ripening-100626180","NCT07432282","Evaluation of the INGA Sensor System for Fetal and Uterine Monitoring During Cervical Ripening","Early Feasibility Study on the Safety and Performance of the INGA Sensor System for Fetal and Uterine Monitoring During Cervical Ripening With the INGA Balloon Catheter","INGA-SEN","Inclusion Criteria:\n\nPregnant women aged ≥18 and ≤56 years An unripe cervix, see below Planned induction of labor by mechanical balloon catheter method Gestational age at the time of the study ≥ 37 weeks Singleton pregnancy Cephalic presentation The subject understands the study information and signs the informed consent\n\nExclusion Criteria:\n\n* Preterm induction of labor (\\\u003C37 weeks of gestation)\n* Clinical active vaginal or uterine infection\n* Abnormal cardiotocography (CTG) at inclusion\n* Spontaneous rupture of membranes at inclusion\n* Clinically significant vaginal bleeding with need of hospitalization in the third trimester\n* Maternal HIV, hepatitis C, or hepatitis B\n* Condition requiring immediate delivery of the fetus or mother\n* Presence of eclampsia\n* Severe Preeclampsia (Blood pressure ≥160\u002F110 and any of the following: HELLP (Hemolysis, Elevated Liver enzymes, and Low Platelet count \\\u003C100 × 10 9\u002FL syndrome), progressive renal insufficiency, pulmonary edema)\n* Severe fetal growth restriction (FGR, growth \\\u003C -2 SD\u002F\\\u003C10th percentile)\n* Estimated fetal weight ≥ 2SD or ≥ 95th percentile\n* Breech or transverse fetal position\n* Multiple pregnancy\n* Vasa previa or placenta previa\n* Uterine scar (including previous caesarean section)\n* Umbilical cord prolapse\n* Bishop score ≥6 on cervical assessment prior to labor induction\n* Reduced amniotic fluid volume (deepest vertical pocket \\\u003C30 mm)\n* Receiving epidural anesthesia prior to catheter insertion\n* Refusal to participate in the study and\u002For insufficient language skills to understand the study information and\u002For consent form",{"count":109,"type":22},120,[25],"The goal of this clinical trial is to learn about the safety and performance of the INGA Sensor System when used with the INGA balloon catheter during cervical ripening for labor induction in pregnant individuals at term. Cervical ripening is a process used to prepare the cervix for labor.\n\nThe main questions it aims to answer are:\n\n* Is the INGA Sensor System safe to use during cervical ripening with the INGA balloon catheter?\n* How well does the sensor system measure uterine contractions and fetal heart rate during cervical ripening?\n* How does the use of the INGA balloon catheter affect cervical ripening and the time from induction to delivery?\n* How do participants and healthcare professionals evaluate the usability of the catheter and sensor system?\n\nAll participants in this study will receive the INGA balloon catheter with the attached sensor system. There is no comparison group.\n\nParticipants will:\n\n* Undergo routine assessments before labor induction, including medical history review, cervical examination, blood pressure and heart rate measurement, and fetal heart rate monitoring\n* Have the INGA balloon catheter placed in the cervix by a trained physician\n* Have a small sensor device attached to the external end of the catheter\n* Undergo standard fetal heart rate monitoring after placement\n* Keep the catheter and sensor in place until the catheter is expelled naturally or for up to 24 hours\n* Continue labor induction and delivery according to standard hospital practice\n* Complete a questionnaire about comfort and usability\n* Allow collection of information about labor, delivery, and newborn outcomes from medical records\n\nParticipation lasts from signing informed consent until hospital discharge.",[61,29,30,113],"Balloon Catheter for Labor Induction",[115,63,29,116,117],"Induction of labour","Uterine monitoring","Fetal monitoring","2026-02-19",{"date":120,"type":39},"2026-02-25",{"date":122,"type":22},"2026-05-01",{"date":124,"type":22},"2027-05-01",{"name":45,"class":46},{"id":127,"slug":128,"hasResults":11,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":132,"eligibilityCriteria":133,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":134,"targetDuration":4,"studyType":23,"phases":136,"briefSummary":137,"conditions":138,"keywords":140,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":99},"100621110","pge2-followed-by-oxytocin-vs-oxytocin-in-term-prom-poxy-prom-100621110","NCT07366359","PGE2 Followed by Oxytocin vs Oxytocin in Term PROM (POXY-PROM)","Comparison of the Effectiveness of Labor Induction Using Dinoprostone Followed by Oxytocin Versus Oxytocin Alone in Term Pregnancies With Premature Rupture of Membranes and an Unfavorable Cervix - A Randomized Clinical Trial","POXY-PROM","Inclusion Criteria\n\n* Maternal age ≥ 18 years\n* Gestational age from 37 to 42 weeks, determined by last menstrual period or by a first- or second-trimester ultrasound\n* Live singleton fetus\n* Prelabor rupture of membranes (PROM) confirmed by at least one of the following:\n\n  * Amniotic fluid visibly draining from the cervical os during sterile speculum examination\n  * Pool of fluid in the posterior fornix\n* Cephalic presentation\n* Bishop score ≤ 6\n* No spontaneous uterine contractions\n* No contraindications for vaginal delivery\n\nExclusion Criteria:\n\n* Active labor\n* Previous uterine surgery (e.g., cesarean section)\n* Chorioamnionitis or non-reassuring fetal status\n* Major fetal anomalies\n* Contraindications to prostaglandin or vaginal delivery\n* Refusal to participate",{"count":135,"type":22},450,[25],"This study is being done to learn more about the best way to start labor for pregnant women whose water breaks at term before labor begins, a condition called term prelabor rupture of membranes (term PROM). When this happens and the cervix is not ready for labor, it is unclear which induction method works best and is safest for mother and baby.\n\nThe purpose of this study is to compare two common ways to induce labor in women with term PROM and an unfavorable cervix (Bishop score ≤ 6). One group will receive a vaginal dinoprostone insert (Propess) for 6 hours to soften the cervix, followed by oxytocin if labor does not start. The other group will receive immediate oxytocin through a vein.\n\nPregnant women aged 18 years or older with a single baby in head-down position at 37-42 weeks, whose water has broken and whose cervix is not yet favorable, may be able to join this study. All care will be provided at the National Hospital of Obstetrics and Gynecology in Hanoi, Vietnam, where both medicines are already used in routine practice.\n\nThe main outcome is how many women have a vaginal birth. The study will also look at how long it takes from induction to birth, complications for mothers and babies, and women's experiences of labor. The results may help doctors choose the safest and most effective way to induce labor for women with term PROM in the future.",[139,85,29],"Premature Rupture of Fetal Membranes",[139,141,142,143,29,144],"Labor Induction","Dinoprostone","Oxytocin","Vaginal Delivery","2026-02-18",{"date":147,"type":39},"2026-02-20",{"date":149,"type":39},"2026-02-10",{"date":151,"type":22},"2028-01",{"name":153,"class":46},"National Hospital of Obstetrics and Gynecology",{"id":155,"slug":156,"hasResults":11,"nctId":157,"briefTitle":158,"officialTitle":159,"acronym":4,"eligibilityCriteria":160,"healthyVolunteers":78,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":161,"targetDuration":4,"studyType":23,"phases":163,"briefSummary":164,"conditions":165,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":166,"lastUpdatePostDateStruct":167,"startDateStruct":169,"completionDateStruct":171,"leadSponsor":173,"locationsCount":4},"100617365","combined-nipple-stimulation-and-foley-balloon-for-cervical-ripening-100617365","NCT07317674","Combined Nipple Stimulation and Foley Balloon for Cervical Ripening","The Effect of Nipple Stimulation Combined With Foley Balloon Catheter on Bishop Score and Induction-to-delivery Interval: a Prospective Randomized Trial","Inclusion Criteria:\n\n* Pregnant individuals aged ≥18 years\n* Singleton pregnancy\n* Term gestation (37-42 weeks)\n* Cephalic fetal presentation\n* Intact membranes\n* Bishop score \\\u003C6 at enrollment\n* Medical indication for labor induction\n\nExclusion Criteria:\n\n* Multiple gestation\n* Previous cesarean delivery or uterine surgery\n* Contraindication to vaginal delivery\n* Major fetal anomalies\n* Active labor at enrollment\n* Unstable fetal lie or presentation\n* Contraindication to Foley balloon catheter insertion\n* Conditions precluding nipple stimulation (e.g., local breast infection, prior breast surgery involving the nipple)",{"count":162,"type":22},100,[25],"Labor induction rates have increased substantially worldwide, and successful cervical ripening remains a key determinant of induction outcomes. Mechanical cervical ripening with a Foley balloon catheter is widely used and considered safe, while nipple stimulation promotes endogenous oxytocin release and represents a physiologic method for stimulating uterine contractions. However, the combined effect of nipple stimulation and balloon catheter use has not been systematically evaluated.\n\nThis prospective, randomized, double-blinded controlled trial will assess whether the addition of nipple stimulation to Foley balloon catheter cervical ripening improves Bishop score and shortens the induction-to-delivery interval compared with balloon catheter alone. Term pregnant patients (37-42 weeks' gestation) with a singleton, cephalic pregnancy and an unfavorable cervix (Bishop score \\\u003C6) requiring labor induction will be randomized to receive either Foley balloon catheter plus standardized nipple stimulation or Foley balloon catheter alone.\n\nThe primary outcomes are change in Bishop score after catheter removal and time from catheter insertion to delivery. Secondary outcomes include need for additional induction methods, mode of delivery, maternal and neonatal outcomes, pain, patient satisfaction, and breastfeeding rates. The study aims to evaluate the efficacy and safety of incorporating a physiologic intervention into standard mechanical cervical ripening.",[28,29],"2025-12-19",{"date":168,"type":39},"2026-01-05",{"date":170,"type":22},"2026-01-01",{"date":172,"type":22},"2028-01-01",{"name":174,"class":175},"Western Galilee Hospital-Nahariya","OTHER_GOV",{"id":177,"slug":178,"hasResults":11,"nctId":179,"briefTitle":180,"officialTitle":181,"acronym":182,"eligibilityCriteria":183,"healthyVolunteers":78,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":184,"targetDuration":4,"studyType":23,"phases":186,"briefSummary":188,"conditions":189,"keywords":191,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":196,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":203,"locationsCount":205},"100435394","phase-3-oxytocin-vs-prostaglandins-for-labor-induction-of-women-with-an-unfavorable-cervix-after-24h-of-cervical-ripening-100435394","NCT04949633","Oxytocin vs Prostaglandins for Labor Induction of Women With an Unfavorable Cervix After 24h of Cervical Ripening","Oxytocine Versus Prostaglandines Pour le déclenchement du Travail Des Femmes Dont le Col Est défavorable après 24 Heures de Maturation Cervicale : Essai Multicentrique randomisé de Non infériorité","OPIC","Inclusion Criteria:\n\n* Pregnant woman\n* ≥ 18 years old\n* With a singleton cephalic pregnancy\n* ≥37+0 weeks of gestation\n* Gestational age estimated from the first trimester ultrasound (realized between 11+0 and 13+6 weeks of gestation)\n* With a medical indication of labor with a previous pharmacological or mechanical cervical ripening of 24 hours\n* Bishop score ≤ 6 at inclusion (unfavorable cervix)\n* French health insurance policy holder\n* Written informed consent\n\nExclusion Criteria:\n\n* Any measures of legal protection\n* Prior caesarean section or uterine scar\n* Contra-indications to a vaginal delivery\n* Foetus with suspected severe congenital abnormalities\n* Pathological foetal heart rate\n* Contra-indications to ANGUSTA® (oral misoprostol, cervical ripening agent)\n* Contra-indications to PROPESS® (vaginal slow releasing system of dinoprostone, cervical ripening agent)\n* Contra-indications to PROSTINE® (vaginal gel of dinoprostone, cervical ripening agent)\n* Contra-indications for using oxytocin\n* Woman in labor",{"count":185,"type":22},1494,[187],"PHASE3","Twenty-two percent of deliveries in France are induced. In cases where labor is induced and cervix is unfavorable, cervical ripening prior oxytocin administration is advised in order to reduce the risk of cesarean delivery. Cervical ripening agents, pharmacological (prostaglandins) or mechanical are administered during 24 hours. After 24 hours, most women will be either delivered or in labor but 25% of women will require further induction of labor. For 16% of women who undergo cervical ripening, whatever the cervical ripening method, the cervix remains unchanged after 24 hours. The management of these women is not consensual and depends on the maternity unit where women are cared for.\n\nThis study seeks to identify the most appropriate strategy for the management of women with an unfavorable cervix after 24 hours of cervical ripening, a strategy which would be associated with the lowest maternal and perinatal morbidity but also with the best maternal satisfaction. Because both strategies are practiced in France, the trial would compare: induction of labor with oxytocin and repeated cervical ripening. The aim is to show that repeating cervical ripening is an unnecessary procedure. And more specifically that oxytocin administration is not associated with a higher caesarean delivery rate and that it reduces the time to delivery in comparison with cervical ripening with prostaglandins.",[29,190],"Unfavorable Cervix",[192,193,194,195],"cervical ripening","oxytocin","prostaglandin","cesarean delivery","2025-11-27",{"date":198,"type":39},"2025-12-01",{"date":200,"type":39},"2021-09-28",{"date":202,"type":22},"2026-11",{"name":204,"class":46},"University Hospital, Tours",12,{"id":207,"slug":208,"hasResults":11,"nctId":209,"briefTitle":210,"officialTitle":211,"acronym":4,"eligibilityCriteria":212,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":213,"enrollmentInfo":214,"targetDuration":4,"studyType":23,"phases":216,"briefSummary":217,"conditions":218,"keywords":220,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":229,"lastUpdatePostDateStruct":230,"startDateStruct":232,"completionDateStruct":234,"leadSponsor":236,"locationsCount":238},"100596256","the-sweep-trial-a-randomized-controlled-trial-100596256","NCT07043088","The SWEEP Trial: a Randomized Controlled Trial","The SWEEP Trial - Serial Versus no Membrane Sweeping on Spontaneous Onset of Labor: a Randomized Controlled Trial","Inclusion Criteria:\n\nSingleton pregnant women at term with a fetus in cephalic presentation and an intended vaginal delivery.\n\nExclusion Criteria:\n\n* \\\u003C 18 years of age\n* Unable to speak and understand Danish\n* Uncertain gestational age , defined as gestational age not determined by Crown-Rump-Length\n* Previous cesarean section\n* Ruptured membranes\n* Painful contractions\n* Vaginal bleeding more than bloody discharge\n* Membrane sweeping performed within the last two weeks\n* Already scheduled IOL or any known indication for IOL at or prior to GA 41+3 based on local or national guidelines\n* Known low-lying placenta (placenta located \\\u003C3 cm from the internal orifice verified by transvaginal ultrasound)","40 Years",{"count":215,"type":22},1536,[25],"The purpose of this clinical trial is to determine whether serial membrane sweeping at term is more effective than no membrane sweeping in promoting spontaneous onset of labor.\n\nThe primary research question is whether serial membrane sweeping increases the likelihood of birth before gestational age 41+3 with spontaneous onset of labor.\n\nA total of 1536 participants will be randomized between gestational age 39+5 and 40+2 to either no membrane sweeping or up to three membrane sweepings performed 2-3 days apart.\n\nResearchers will collect data from the electronic medical record and participants will be asked to complete a short daily questionnaire on pregnancy symptoms and, in the intervention group, their experience of membrane sweeping from randomization until birth. All participants will be asked to complete a follow-up questionnaire about their birth experience five weeks postpartum",[87,29,219],"Memrane Sweeping",[221,192,222,223,224,225,226,227,228],"membrane sweeping","labor onset","term pregnancy","induction of labor","midwifery","randomized controlled trial","post-term pregnancy","membrane stripping","2025-08-29",{"date":231,"type":39},"2025-09-02",{"date":233,"type":39},"2025-06-18",{"date":235,"type":22},"2027-10",{"name":237,"class":46},"University of Aarhus",2]