[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cervical-spondylosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cervical-spondylosis":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,42,75,107,133,166,189,213,236,260],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":4},"100642572","efficacy-of-the-three-needle-dazhui-technique-combined-with-electroacupuncture-for-cervical-spondylosis-with-wind-cold-syndrome-100642572",false,"NCT07640126","Efficacy of the \"Three-Needle Dazhui\" Technique Combined With Electroacupuncture for Cervical Spondylosis With Wind-Cold Syndrome","Evaluation of the Efficacy of the \"Three-Needle Dazhui\" Technique Combined With Electroacupuncture in Managing Pain and Improving Neck Disability in 74 Patients With Cervical Spondylotic Radiculopathy and Wind-Cold Syndrome: A Randomized, Single-Blind, Controlled Trial","Inclusion Criteria:\n\n* Consent: Participants must voluntarily agree to participate and sign a written informed consent form.\n* Age: Individuals aged 18 years or older.\n* Pain Intensity: Patients with a baseline pain score of VAS ≥ 50 mm on the Visual Analog Scale.\n* Modern Medicine Diagnosis (Cervical Spondylotic Radiculopathy - CSR) Patients must meet the diagnostic criteria for CSR due to cervical spondylosis according to Decision 361\u002FQD-BYT, including:\n\n  * Cervical Spine Syndrome: Localized neck pain, restricted range of motion, and tenderness upon palpation of the spinous processes or paravertebral areas.\n\nRadicular Syndrome: Neck pain radiating to the occipital region, shoulder, arm, or hand.\n\n* Physical Examination: At least one positive result from the following tests: Bell-ringer sign, Spurling's test, Shoulder abduction test, or Cervical distraction test.\n* Imaging Criteria: X-ray findings (straight, lateral, or 3\u002F4 oblique views) showing at least one of the following:\n\n  1. Osteophytes (bone spurs) on the vertebral body.\n  2. Intervertebral disc space narrowing ≥ 25%.\n  3. Subchondral bone sclerosis.\n  4. Spondylolisthesis. - Traditional Chinese Medicine (TCM) Diagnosis (Wind-Cold Syndrome) Patients must satisfy at least one primary symptom and reach a total symptom score of ≥ 50% based on the following criteria:\n* Primary Symptoms: Pain in the neck and shoulder radiating to the arm accompanied by numbness; pain is the dominant feature; pain increases with cold and decreases with warmth.\n* Secondary Symptoms: Aversion to cold, aversion to wind, cold extremities, and presence or absence of sweating.\n* Tongue and Pulse: Pale tongue with a thin white coating; floating-tight or slow pulse.\n\nExclusion Criteria:\n\n* History of neck trauma.\n* Diagnosed with specific bone or joint diseases: Rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, Down syndrome, cervical spina bifida, or Scheuermann's disease.\n* Severe motor or sensory radicular disorders: Muscle weakness or sensory disturbances such as burning, tingling, or numbness in the shoulder, arm, or hand.\n* Vertebral-basilar artery syndrome: Headache, dizziness, tinnitus, loss of balance, or fatigue.\n* Autonomic nervous system disorders: Pain accompanied by tinnitus, visual disturbances, or vasomotor disorders in the occipital-shoulder region or arms.\n* Central motor neuron lesions: Presence of Hoffmann's sign, Babinski's sign, hyperreflexia, spasticity, urinary\u002Ffecal incontinence, or sexual dysfunction.\n* Symptoms suggesting systemic or malignant disease: Unexplained weight loss, fever, loss of appetite, personal or family history of malignant tumors, or diffuse pain and stiffness.\n* Symptoms suggesting infection: Fever, meningeal signs, or photophobia.\n* Symptoms suggesting serious acute medical conditions: Myocardial infarction (chest pain + sweating + shortness of breath) or arterial dissection (tearing pain sensation + headache + blurred vision).\n* Local or systemic contraindications: Infection or ulceration at the acupuncture site; patients who are exhausted, emaciated, or suffering from severe accompanying internal medical diseases.\n* Substance abuse: Alcohol or drug addiction.\n* Recent medication use (within the past month): Currently using analgesics or anti-inflammatory drugs that may affect results, such as Opioids, NSAIDs, Corticosteroids, Gabapentin, Pregabalin, or tricyclic antidepressants.\n* Other ongoing treatments: Currently undergoing other therapies such as acupressure, massage, or physical therapy for the neck area.","ALL","18 Days",{"count":19,"type":20},74,"ESTIMATED","INTERVENTIONAL",[23],"NA","Cervical spondylosis is a prevalent health issue that significantly impacts quality of life, with Cervical Spondylotic Radiculopathy (CSR) accounting for 60-70% of cases\n\n* While modern medicine offers various treatments, the frequent use of painkillers often leads to undesirable side effects\n* In Traditional Chinese Medicine, electroacupuncture is a safe and effective method recognized by the Ministry of Health for treating this condition\n* The \"Three-Needle Dazhui\" technique is a specialized acupuncture method that simultaneously uses three needles at the Dazhui (GV14) point to strongly activate Yang Qi and dispel cold, making it particularly suitable for the Wind-Cold syndrome. This study aims to evaluate whether the combination of the Three-Needle Dazhui technique and electroacupuncture yields better results in pain reduction and functional improvement compared to electroacupuncture alone in patients with cervical spondylosis and Wind-Cold syndrome.",[26,27,28,29],"Cervical Spondylosis","Wind-Cold Syndrome","Neck Pain","Cervical Spondylotic Radiculopathy","NOT_YET_RECRUITING","2026-06-08",{"date":33,"type":34},"2026-06-10","ACTUAL",{"date":36,"type":20},"2026-06-01",{"date":38,"type":20},"2026-09",{"name":40,"class":41},"University of Medicine and Pharmacy at Ho Chi Minh City","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100643683","prospective-case-series-evaluating-6-month-and-12-month-outcomes-after-cryoneurolysis-for-chronic-pain-100643683","NCT07639060","Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain","Inclusion Criteria:\n\n* Diagnosis of chronic pain (generally pain duration of at least 3-6 months) localized to an anatomical region appropriate for cryoneurolysis as determined by the treating physician.\n* Planned cryoneurolysis procedure as part of standard clinical care.\n* Ability to provide written informed consent.\n* Ability and willingness to complete baseline and follow-up questionnaires.\n\nExclusion Criteria:\n\n* Cryoneurolysis performed as part of a separate investigational trial in which data sharing is not permitted.\n* Active infection or other clinical contraindication to the procedure as determined by the treating clinician.\n* Life expectancy of less than 12 months in the judgment of the treating clinician.\n* Any condition that, in the investigator's opinion, would interfere with study participation or completion of follow-up, such as severe psychiatric instability or active substance use that precludes reliable follow-up","18 Years",{"count":50,"type":20},80,"OBSERVATIONAL","To prospectively describe patient-centered and health utilization outcomes through 12 months after cryoneurolysis performed as routine clinical care for chronic pain at Yale.",[54,55,56,57,58,59,60,61,62,26,63,64,65,66],"Chronic Pain","PERIPHERAL NEUROPATHY","Occipital Neuralgia","Chronic Hip Pain","Hip Osteoarthritis","Knee Osteoarthritis","Spasticity","Chronic Low Back Pain","Lumbar Spondylosis","Shoulder Arthritis","Causalgia","Chronic Pain Syndrome","Chronic Neck Pain","2026-06-05",{"date":33,"type":34},{"date":70,"type":20},"2026-06",{"date":72,"type":20},"2028-07",{"name":74,"class":41},"Yale University",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":21,"phases":84,"briefSummary":85,"conditions":86,"keywords":89,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":106},"100635833","transcutaneous-auricular-vagus-nerve-stimulation-combined-with-cervical-epidural-injection-for-cervical-radiculopathy-100635833","NCT07557823","Transcutaneous Auricular Vagus Nerve Stimulation Combined With Cervical Epidural Injection for Cervical Radiculopathy","Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Combined With Cervical Epidural Injection in the Treatment of Cervical Radiculopathy: A Randomized, Double-Blind, Sham-Controlled Trial.","Inclusion Criteria:\n\n1. Age between 18 and 85 years old.\n2. Body Mass Index (BMI) between 18 and 35 kg\u002Fm².\n3. American Society of Anesthesiologists (ASA) physical status I to III.\n4. Diagnosed with cervical radiculopathy, scheduled for selective cervical epidural injection.\n5. Estimated procedure duration ≤ 1 hour.\n6. Able to understand and provide written informed consent.\n\nExclusion Criteria:\n\n1. Arrhythmia requiring treatment, severe bradycardia, or postural orthostatic tachycardia syndrome.\n2. Neuromuscular disorders or auricular dermatitis.\n3. Cervical fracture, tumor, tuberculosis, or active infection confirmed by imaging.\n4. Contraindications to vagus nerve stimulation: carotid sinus hypersensitivity, bilateral carotid artery stenosis.\n5. Severe psychiatric disorder or history of substance abuse.","85 Years",{"count":50,"type":20},[23],"This is a prospective, randomized, double-blinded, sham-controlled trial conducted to investigate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) combined with cervical epidural injection in the treatment of cervical radiculopathy. A total of 80 subjects will be enrolled and randomly assigned (1:1) to either the experimental group or the control group. The primary outcome measure is the proportion of subjects with a ≥50% reduction in the Numerical Rating Scale (NRS) pain score at discharge. Secondary outcomes include pain intensity, pain interference, psychological status, sleep quality, physical disability, and autonomic function measurements. Adverse events will be monitored throughout the study.",[87,26,88],"Cervical Radiculopathy","Radicular Pain",[90,91,92,93,94,95,96],"taVNS","transcutaneous auricular vagus nerve stimulation","cervical epidural injection; cervical radiculopathy","pain","arm pain","pain management","neuromodulation","2026-04-26",{"date":99,"type":34},"2026-04-29",{"date":101,"type":20},"2026-04-10",{"date":103,"type":20},"2027-03-31",{"name":105,"class":41},"Second Affiliated Hospital, School of Medicine, Zhejiang University",1,{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":111,"acronym":4,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":16,"minAge":113,"maxAge":114,"enrollmentInfo":115,"targetDuration":4,"studyType":21,"phases":117,"briefSummary":118,"conditions":119,"keywords":120,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":4},"100631587","effect-of-vestibular-rehabilitation-on-evoked-myogenic-potentials-in-patients-with-cervical-spondylosis-100631587","NCT07502625","Effect of Vestibular Rehabilitation on Evoked Myogenic Potentials in Patients With Cervical Spondylosis","Inclusion Criteria:\n\n* Adult patients (40-to-60 years old) diagnosed as cervical spondylosis with vestibular dysfunction manifestation (Shi et al., 2024).\n* Normal BMI 20-to-25 kg\u002Fm².\n* All patients have chronic neck pain lasting for more than 3 months (Sadeghi et al., 2022).\n* The area of chronic neck pain will defined to the cervical region, possibly with referred pain into the occipit, nuchal muscles, and shoulders.\n\nExclusion Criteria:\n\n* Signs of serious pathology (e.g., rheumatoid diseases, ankylosing spondylitis, tumor),\n* History of cervical spine surgery,\n* History of trauma or fractures in cervical spine, and\n* Signs of vascular syndrome such as vertebrobasilar insufficiency and no usage of non steroidal anti-inflammatory drugs two weeks before treatment (Sadeghi et al., 2022).","40 Years","60 Years",{"count":116,"type":20},62,[23],"This study will Investigate the effect of vestibular rehabilitation on:\n\nPrimary outcomes: Vestibular evoked myogenic potentials, Balance,and Cervical proprioception.\n\nSecondary outcomes: Functional disability and pain intensity level",[26],[121,122,123],"Cervical spondylosis","Evoked myogenic potentials","Vestibular rehabilitation","2026-03-27",{"date":126,"type":34},"2026-03-31",{"date":128,"type":20},"2026-04",{"date":130,"type":20},"2026-08",{"name":132,"class":41},"Cairo University",{"id":134,"slug":135,"hasResults":11,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":4,"eligibilityCriteria":139,"healthyVolunteers":11,"sex":16,"minAge":113,"maxAge":4,"enrollmentInfo":140,"targetDuration":4,"studyType":21,"phases":142,"briefSummary":143,"conditions":144,"keywords":145,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":106},"100604583","efficacy-of-acupuncture-at-lieque-lu7-for-neck-pain-in-cervical-spondylosis-100604583","NCT07151404","Efficacy of Acupuncture at Lieque (LU7) for Neck Pain in Cervical Spondylosis","Efficacy of Acupuncture at Lieque (LU7) Based on Six Command Points Theory, Combined With Electroacupuncture at Jiaji (Ex-B2, C4-C7) and Cervical-Shoulder Points in Cervical Spondylosis","Inclusion Criteria:\n\n* Age 40 years or older\n* Diagnosis of cervical spondylosis based on clinical evaluation and imaging.\n* Presence of cervical spine syndrome, including:\n\n  * Neck and shoulder pain.\n  * Limited range of motion in the cervical spine.\n  * Local tenderness over the cervical spine or paraspinal region corresponding to nerve roots.\n* Radiographic evidence of cervical spondylosis on standard X-ray (frontal, lateral, or oblique views), showing one or more of the following:\n\n  * Subchondral sclerosis.\n  * Narrowing of the intervertebral disc space.\n  * Osteophyte formation (bone spurs, bridging osteophytes).\n* Patients receiving treatment at Thu Duc City Hospital\n\nExclusion Criteria:\n\n* Patients who do not agree to participate in the study.\n* Acute torticollis, cervical disc herniation, spinal deformity, cervical spine trauma, or spinal tumors.\n* Neck and shoulder pain not caused by cervical spondylosis.\n* History of systemic diseases such as rheumatoid arthritis, severe cardiovascular disease, systemic infection, malignancy, or immunodeficiency disorders.\n* History of neurological or psychiatric conditions that impair communication or compliance, including speech disorders, impaired consciousness, psychosis, or dementia.\n* Contraindications to electroacupuncture.\n* Non-compliance with study treatment protocol.\n* Use of non-steroidal anti-inflammatory drugs (NSAIDs) within the past 10 days or local corticosteroid injection within the past 3 months.",{"count":141,"type":20},130,[23],"Cervical spondylosis is a common degenerative disorder of the cervical spine that often leads to chronic neck pain, stiffness, and reduced daily functioning. Pain management in these patients remains challenging, and acupuncture is widely used as a non-pharmacological treatment option. However, the additional benefit of stimulating the Lieque (LU7) acupoint, based on the Six Command Points theory, has not been fully established.\n\nThis randomized controlled trial will evaluate whether acupuncture at Lieque (LU7), combined with electroacupuncture at Jiaji (Ex-B2, C4-C7) and cervical-shoulder points, provides greater pain relief compared to electroacupuncture at Jiaji (Ex-B2, C4-C7) and cervical-shoulder points alone.\n\nA total of 130 participants with cervical spondylosis will be randomly assigned to two groups. Treatments will be delivered over 20 days. The primary outcome is the change in neck pain intensity, measured by a 0-100 mm Visual Analog Scale (VAS), from baseline to the end of treatment.\n\nThe findings will provide clinical evidence on the effectiveness of acupuncture at Lieque (LU7) for reducing neck pain and improving patient outcomes in cervical spondylosis.",[26,28],[26,28,146,147,148,149,150,151,152,153,154,155,156],"Cervical Spine","Acupuncture","Electroacupuncture","Lieque Point","LU7 Acupoint","Jiaji Points","Cervical-Shoulder Acupoints","Randomized Controlled Trial","LU7","Ex-B2","Ex-B2, C4-C7","2025-08-28",{"date":159,"type":34},"2025-09-03",{"date":161,"type":20},"2025-09-01",{"date":163,"type":20},"2026-03-01",{"name":165,"class":41},"Nguyen Ngoc Doan Thuy",{"id":167,"slug":168,"hasResults":11,"nctId":169,"briefTitle":170,"officialTitle":171,"acronym":4,"eligibilityCriteria":172,"healthyVolunteers":11,"sex":16,"minAge":173,"maxAge":114,"enrollmentInfo":174,"targetDuration":4,"studyType":21,"phases":176,"briefSummary":177,"conditions":178,"keywords":179,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":181,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":4},"100584732","cupping-therapy-for-neck-pain-in-cervical-spondylosis-100584732","NCT06893185","Cupping Therapy for Neck Pain in Cervical Spondylosis","Effectiveness of Cupping Therapy in Managing Neck Pain and Improving Cervical Mobility in Cervical Spondylosis Patients: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Individuals between the ages of 20 and 60 years, outpatient treatment.\n* Individuals diagnosed with cervical spondylosis.\n* Individuals report pain intensity between 3 and 8 according to on the Visual Analogue Scale (VAS) on the screening visit day.\n* Experiencing neck pain for no longer than four weeks.\n* Individuals who volunteered to participate in the study and signed a consent form.\n\nExclusion Criteria:\n\n* Patients diagnosed with acute or chronic neck pain due to specific causes or with root compression syndrome, spinal cord compression syndrome, or vertebral artery syndrome.\n* Patients loss of normal cervical curvature or deformity.\n* Individuals with a history of neck trauma, cervical vertebra fracture, or cervical spine surgery, congenital spinal abnormalities, systemic bone and joint diseases.\n* Patients have undergone cupping therapy, plastering, or drug inhalation within one week prior to participating in the study.\n* Patients used of medications that could affect research outcomes within one week: Pain relievers, muscle relaxants, traditional medicines for treating neck pain.\n* Patients suffer from a mental illness or lacks consciousness.\n* Patients have a pacemaker, or any metal devices such as screws or plates.\n* Patients currently using anticoagulant medications or has a bleeding disorder.","20 Years",{"count":175,"type":20},82,[23],"Cervical spondylosis is one of the common causes of chronic neck pain. It can significantly affect the quality of life, lead to disabilities, and increase the economic burden on patients. Treatment mainly includes pain relievers, non-steroidal anti-inflammatory drugs (NSAIDs), muscle relaxants or physical therapy. The condition tends to recur frequently; therefore, long-term use of medication can lead to unwanted effects on the digestive system, kidneys, and cardiovascular system.\n\nDry cupping therapy is a non-pharmacological method that has been shown to be effective in pain management. Cupping therapy has the advantage of being applicable to patients who are afraid of needles and has a wide area of effect.\n\nGiven the limitations in evaluating treatment effectiveness and safety, along with the lack of published research discussing the analgesic effects of dry cupping for neck pain caused by cervical spondylosis, the investigators conducted the study on pain reduction and safety of cupping therapy in patients with neck pain caused by cervical spondylosis.",[28,26],[28,180,121],"Cupping therapy","2025-05-23",{"date":183,"type":34},"2025-05-29",{"date":185,"type":20},"2025-06-01",{"date":187,"type":20},"2025-08-31",{"name":40,"class":41},{"id":190,"slug":191,"hasResults":11,"nctId":192,"briefTitle":193,"officialTitle":194,"acronym":4,"eligibilityCriteria":195,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":196,"enrollmentInfo":197,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":199,"conditions":200,"keywords":4,"overallStatus":202,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":210,"locationsCount":212},"100562320","predictors-of-axial-pain-improvement-after-anterior-cervical-discectomy-and-fusion-100562320","NCT06601634","Predictors of Axial Pain Improvement After Anterior Cervical Discectomy and Fusion","Predictors of Axial Pain Improvement After Anterior Cervical Discectomy and Fusion - Prospective, Observational Study","Inclusion Criteria:\n\n* Ability to provide informed consent\n* Patients who are qualified for one- or two-level ACDF for the treatment of degenerative cervical pathology\n\nExclusion Criteria:\n\n* Previous cervical spine surgery\n* Previous cervical spine trauma\n* Other diseases causing neck pain include rheumatoid arthritis, lupus, polymyalgia rheumatica, myositis, seronegative inflammatory diseases, and fibromyalgia\n* Drug abuse\n* Myelopathy\n* Spinal infection\n* VAS neck pain score less than 3 (Inability to achieve an MCID which is calculated as 2.5 for the VAS scale)","65 Years",{"count":198,"type":20},60,"Neck pain is a common, multifactorial condition. In the case of degenerative cervical spinal disease, it can result from changes in the intervertebral discs, muscles, intervertebral joints, or sagittal imbalance. Anterior cervical discectomy and fusion (ACDF) is a currently widely accepted procedure for treating cervical degenerative spine disease, with a high patient satisfaction rate. In the current state of knowledge, it is not used for treating axial neck pain, but rather in cases of discopathy causing spinal myelopathy or cervical radiculopathy, in which neck pain often coexists or predominates. The current literature provides ample evidence of the significant effect of ACDF in improving axial neck pain in the conditions mentioned previously. However, little information exists on which patients achieve improvement. The aim of this prospective study is to analyze the outcomes of ACDF in patients with neck pain and to identify predictors of reduction in axial neck pain after ACDF.",[28,26,201],"Cervical Disc Disease","RECRUITING","2025-03-25",{"date":205,"type":34},"2025-03-26",{"date":207,"type":34},"2024-11-17",{"date":209,"type":20},"2027-12",{"name":211,"class":41},"Medical University of Warsaw",2,{"id":214,"slug":215,"hasResults":11,"nctId":216,"briefTitle":217,"officialTitle":218,"acronym":4,"eligibilityCriteria":219,"healthyVolunteers":11,"sex":16,"minAge":220,"maxAge":221,"enrollmentInfo":222,"targetDuration":4,"studyType":21,"phases":224,"briefSummary":225,"conditions":226,"keywords":4,"overallStatus":202,"whyStopped":4,"lastUpdateSubmitDate":227,"lastUpdatePostDateStruct":228,"startDateStruct":230,"completionDateStruct":232,"leadSponsor":234,"locationsCount":106},"100552983","radiofrequency-plus-superficial-cervical-plexus-block-in-treatment-of-cervical-spondylosis-pain-100552983","NCT06480175","Radiofrequency Plus Superficial Cervical Plexus Block in Treatment of Cervical Spondylosis Pain","Comparative Study Between Cervical Medial Branch Radiofrequency Ablation Versus Radiofrequency Plus Superficial Cervical Plexus Block in Treatment of the Cervical Facet and Cervical Spondylosis Pain","Inclusion Criteria:\n\n* Both genders.\n* Age between 30-70 years.\n* American society of anesthesiologist ASA 1,2 \\& 3 physical status.\n* MRI cervical spine diagnosing cervical facet arthropathy originating pain .\n* Failed full dose medical treatment and life style modification and physiotherapy for 3 months prior to intervention.\n\nExclusion Criteria:\n\n* Neurological disorders.(previous central and peripheral CNS affection ).\n* coagulopathy INR \\> 1.8 or platelets \\\u003C 50,000.\n* Infection at or near the injection site.\n* Presence of pacemaker or defibrillator.\n* known allergy to used medications.\n* age \\>70 or \\\u003C30 years.\n* patients with previous history of Radiotherapy , chemotherapy or metastasis\n* pregnant patients.\n* patients with rheumatological disorders ( rheumatoid arthritis, diffuse idiopathic skeletal hyerostosis, psoriatic arthritis, spondyloarthritis)\n* patients with antiphospholipid syndtrome.","30 Years","70 Years",{"count":223,"type":20},53,[23],"The goal of this clinical trial is to compare the effectiveness in the pain relief between doing radiofrequency ablation for the medial branch of the cervical facet pain alone vs using it combined with superficial cervical plexus block.in adults patients with cervical spondylosis pain\n\nThe main question it aims to answer is:\n\ndoes adding superficial cervical plexus block to radiofrequency in patients with chronic neck pain provide better analgesia than radioprequency alone ?",[28,26],"2024-06-24",{"date":229,"type":34},"2024-06-28",{"date":231,"type":34},"2024-06-20",{"date":233,"type":20},"2024-12",{"name":235,"class":41},"Ain Shams University",{"id":237,"slug":238,"hasResults":11,"nctId":239,"briefTitle":240,"officialTitle":241,"acronym":4,"eligibilityCriteria":242,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":243,"targetDuration":4,"studyType":21,"phases":245,"briefSummary":246,"conditions":247,"keywords":4,"overallStatus":202,"whyStopped":4,"lastUpdateSubmitDate":251,"lastUpdatePostDateStruct":252,"startDateStruct":254,"completionDateStruct":256,"leadSponsor":258,"locationsCount":106},"100310391","enhancing-recovery-in-non-traumatic-spinal-cord-injury-100310391","NCT03320759","Enhancing Recovery in Non-Traumatic Spinal Cord Injury","Enhancing Recovery in Non-Traumatic Spinal Cord Injury: Implementation of an Integrated Program for the Assessment of Rehabilitation Therapies","Inclusion Criteria:\n\n* right-handed\n* have a history of progressive neurological deficits \\\u003C24 months\n* eligible for MRI scanning\n\nExclusion Criteria:\n\n* having any other neurological disorder or systemic disease that can impair neurological function\n* not fluent in reading and speaking English\n* being claustrophobic\n* unable to follow simple task instructions and maintain standardized movements\n* being unable to return for all follow-up imaging and rehabilitation sessions",{"count":244,"type":20},40,[23],"The investigators have spent the last decade uncovering unique metabolic and functional abnormalities in the brains of patients with spinal cord compression. Degenerative spinal cord compression represents a unique model of reversible spinal cord injury. In the investigator's previous work, they have demonstrated that cortical reorganization and recruitment is associated with metabolic changes in the brains of patients recovering from spinal cord compression and is correlated with recovery and improved neurological scores.\n\nThe goal of this study is to combine a rigorous platform of clinical care that includes preoperative evaluation, surgery, and rehabilitation, with state of the art imaging techniques to demonstrate how rehabilitative therapy can increase brain plasticity and recovery of neurological function in patients with spinal cord injury. Neurological function will be carefully evaluated in two groups of patients, those receiving rehabilitation and those not receiving rehabilitation after spine surgery, and will be correlated with the results of advanced imaging.",[248,249,26,250],"Spinal Cord Compression","Spinal Cord Injuries","Myelopathy Cervical","2024-03-26",{"date":253,"type":34},"2024-03-28",{"date":255,"type":34},"2018-08-21",{"date":257,"type":20},"2026-07-01",{"name":259,"class":41},"Western University, Canada",{"id":261,"slug":262,"hasResults":11,"nctId":263,"briefTitle":264,"officialTitle":265,"acronym":266,"eligibilityCriteria":267,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":268,"targetDuration":4,"studyType":21,"phases":270,"briefSummary":271,"conditions":272,"keywords":289,"overallStatus":202,"whyStopped":4,"lastUpdateSubmitDate":304,"lastUpdatePostDateStruct":305,"startDateStruct":307,"completionDateStruct":309,"leadSponsor":311,"locationsCount":106},"100410368","cervical-arthroplasty-cost-effectiveness-study-caces-100410368","NCT04623593","Cervical Arthroplasty Cost Effectiveness Study (CACES)","Economic Evaluation of Anterior Cervical Discectomy With Arthroplasty Versus Anterior Cervical Discectomy With Fusion in the Surgical Treatment of Cervical Degenerative Disc Disease, a Randomized Controlled Trial","CACES","Inclusion Criteria:\n\n* Indication for anterior cervical decompression surgery.\n* Single- or multilevel CDDD between C3 and C7.\n* Symptoms of myelopathy, radiculopathy, or myeloradiculopathy.\n* In case of pure radiculopathy: refractory to at least 6 weeks of conservative therapy.\n* In case of myelopathy: symptomatic myelopathy.\n* Patients ≥ 18 years of age.\n\nExclusion criteria\n\n* Indication for (additional) posterior surgical approach.\n* Indication for additional stabilization of the pathological segment by a plate.\n* Previous ventral surgery of the cervical spine.\n* Traumatic origin of the compression.\n* Previous radiotherapy of the cervical spine.\n* Metabolic bone disease.\n* Inflammatory spinal disease: e.g., Bechterew's disease, Forestier's disease.\n* Infection of the cervical spine.",{"count":269,"type":20},198,[23],"To date, no consensus exists on which anterior surgical technique is more cost-effective to treat cervical degenerative disc disease (CDDD). The most commonly used surgical treatment for patients with single- or multilevel symptomatic CDDD is anterior cervical discectomy with fusion (ACDF). However, new complaints of radiculopathy and\u002For myelopathy commonly develop at adjacent levels, also known as clinical adjacent segment pathology (CASP). It remains unknown to what extent kinematics, surgery-induced fusion and natural history of disease play a role in its development. Anterior cervical discectomy with arthroplasty (ACDA) is thought to reduce the incidence of CASP by preserving motion in the operated segment. ACDA is often discouraged as the implant costs are higher whilst the clinical outcomes are similar to ACDF. However, preventing CASP might be a reason for ACDA to be a more cost-effective technique in the long-term.\n\nIn this randomized controlled trial patients will be randomized to receive ACDF or ACDA in a 1:1 ratio. Adult patients with single- or multi-level CDDD and symptoms of radiculopathy and\u002For myelopathy will be included. The primary outcome is cost-effectiveness and cost-utility of both techniques from a societal perspective. Secondary objectives are the differences in clinical and radiological outcomes between the two techniques, as well as the qualitative process surrounding anterior decompression surgery. All outcomes will be measured at baseline and every 6 months till 4 years postoperatively.\n\nHigh quality evidence regarding the cost-effectiveness of both ACDA and ACDF is lacking, to date no prospective trials from a societal perspective exist. Considering the ageing of the population and the rising healthcare costs, the need for a solid clinical cost-effectiveness trial addressing this question is high.",[273,250,274,275,276,277,278,279,201,280,281,282,283,26,284,285,286,287,288],"Radiculopathy, Cervical","Myelopathy, Compressive","Radiculopathy, Cervical Region","Radiculopathy; in Spondylosis","Radiculopathy; in Intervertebral Disc Disorder","Myelopathy Neurological","Myelopathy Due to Spondylosis","Cervical Disc Herniation","Cervical Disc Degeneration","Cervical Disc Disorder With Myelopathy","Cervical Disc Prolapse With Myelopathy","Cervical Fusion","Cervical Disc Disorder With Radiculopathy","Cervical Disc Prolapse With Radiculopathy","Fusion of Spine","Disc Prolapse Cervical",[290,291,292,293,294,295,296,297,298,299,300,301,302,303],"Cost-effectivity","Economic evaluation","Health Utility","Randomised controlled trial","RCT","ACDA","ACDF","Anterior cervical discectomy and fusion","Anterior cervical discectomy with arthroplasty","Degenerative cervical myelopathy","Degenerative cervical radiculopathy","ASD","Adjacent Segment Disease","Adjacent Level Disease","2024-01-24",{"date":306,"type":34},"2024-01-25",{"date":308,"type":34},"2022-01-17",{"date":310,"type":20},"2028-06-01",{"name":312,"class":41},"Valérie Schuermans"]