[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cervix-uteri-sil\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cervix-uteri-sil":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100527409","regression-of-cervical-precancerous-lesions-and-associated-risk-factors-100527409",false,"NCT06147388","Regression of Cervical Precancerous Lesions and Associated Risk Factors","RECER","Inclusion Criteria:\n\n1. squamocolumnar junction fully visualized\n2. bioptically verified CIN 2 or CIN 3\n3. age ≥ 18 years\n4. age ≤ 40 years\n5. informed consent\n\nExclusion Criteria:\n\n1. squamocolumnar junction not fully visualized\n2. suspicion on glandular lesion\n3. suspicion on invasive cancer\n4. personal history of CIN 2, 3 or cerv. cancer\n5. gravidity\n6. HIV positivity\n7. immunosuppression\n8. impossible photographic documentation","FEMALE","18 Years","40 Years",{"count":20,"type":21},300,"ESTIMATED","2 Years","OBSERVATIONAL","The aim of this study is to assess the extent of histopathological regression of severe cervical precancerous lesions (CIN 2 and CIN 3); evaluate the proportion of patients who experience the normalization of HPV test and cytology finding among those who were treated conservatively and those who underwent conization; and identify predictive parameters associated with regression. Based on this analysis, a model will be proposed to predict the likelihood of lesion regression.",[26,27,28,29],"Cervix Uteri SIL","HPV","CIN2","CIN3","RECRUITING","2026-02-22",{"date":33,"type":34},"2026-02-25","ACTUAL",{"date":36,"type":34},"2022-09-01",{"date":38,"type":21},"2027-07-01",{"name":40,"class":41},"General University Hospital, Prague","OTHER"]