[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cesarean-delivery-neuraxial-opioids\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cesarean-delivery-neuraxial-opioids":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100636577","phase-4-adding-dexmedetomidine-or-clonidine-to-spinal-anesthesia-for-cesarean-delivery-100636577",false,"NCT07567495","Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean Delivery","Inclusion Criteria:\n\n* Pregnant women undergoing cesarean delivery with spinal anesthesia\n\nExclusion Criteria:\n\n* Significant cardiovascular, psychiatric or respiratory disease\n* using opioids or with chronic pain syndrome\n* Multiple gestation\n* BMI \\>40 kg\u002Fm2\n* Quaternary or greater cesarean\n* \\\u003C 37 weeks gestation\n* Non-English or Spanish speaking\n* planned vertical skin incision\n* planned vertical (classical) uterine incision\n* allergy to clonidine, dexmedetomidine or other study drug","FEMALE","18 Years",{"count":18,"type":19},150,"ESTIMATED","INTERVENTIONAL",[22],"PHASE4","This study will examine whether addition of dexmedetomidine or clonidine (two alpha-2 adrenergic agonists) will improve the comfort of patients during spinal anesthesia for cesarean delivery. When added to standard spinal anesthesia consisting of bupivacaine (a local anesthetic) and fentanyl and morphine (two opioids), these medications may decrease some of the pulling\u002Ftugging\u002Fpressure sensations that patients sometimes feel during cesarean delivery, may prolong the anesthetic time, and may decrease postoperative pain.",[25,26,27,28,29,30],"Cesarean Delivery","Cesarean Delivery; Neuraxial Opioids","Spinal Anesthesia for Cesarean Section","Dexmedetomidine","Clonidine","Postoperative Analgesia",[32,33,34,35,36,37],"cesarean","dexmedetomidine","clonidine","spinal","anesthesia","Adrenergic alpha-2 Receptor Agonists","NOT_YET_RECRUITING","2026-04-30",{"date":41,"type":42},"2026-05-05","ACTUAL",{"date":44,"type":19},"2026-06",{"date":46,"type":19},"2028-05",{"name":48,"class":49},"Columbia University","OTHER"]