[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cesarean-section-dehiscence\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cesarean-section-dehiscence":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100455141","comparison-of-the-therapeutic-effects-of-vaginal-repair-with-leuprorelin-and-vaginal-repair-in-the-treatment-of-cesarean-section-scar-defect-100455141",false,"NCT05206682","Comparison of the Therapeutic Effects of Vaginal Repair With Leuprorelin and Vaginal Repair in the Treatment of Cesarean Section Scar Defect","Inclusion Criteria:\n\n1. Clearly diagnosed with CSD complicated with adenomyosis\n2. Experiencing clinical features of abnormal uterine bleeding, prolonged menstrual flow (the duration of menstruation is more than 10 days).\n3. The thickness of the remaining muscular layer of CSD was less than 3 mm.\n4. Normal range of blood sugar and insulin\n5. No serious medical problems (important viscera function in the normal range).\n6. uterine fibroids no more than 5cm\n7. Sign the informed consent.\n\nExclusion Criteria:\n\n1. Indefinite diagnosis.\n2. Malignant tumors.\n3. With severe medical problems (severe liver disease, kidney disease, respiratory diseases, heart disease or uncontrolled diabetes, epilepsy, etc., dysfunction of important organs).\n4. Pregnant.\n5. Mental diseases.\n6. Allergy to the any ingredients of Leuprorelin\n7. Unwilling to comply with the research plan.","FEMALE","18 Years","50 Years",{"count":19,"type":20},94,"ESTIMATED","INTERVENTIONAL",[23],"NA","GnRH-a will be used to postpone period after vaginal repair for Cesarean Section Scar Defect（CSD） patients with adenomyosis which will be compared with CSD patients with adenomyosis who receive transvaginal surgery without GnRH-a, whether delayed period improving the CSD prognosis will be assessed.",[26],"Cesarean Section; Dehiscence",[28,29,30],"Cesarean Section Scar Defect","Zoladex","vaginal repair","RECRUITING","2026-04-22",{"date":34,"type":35},"2026-04-24","ACTUAL",{"date":37,"type":35},"2023-05-01",{"date":39,"type":20},"2027-12-30",{"name":41,"class":42},"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":43},"100539771","impact-of-single--versus-double-layer-hysterotomy-closure-on-cesarean-niche-development-a-randomized-controlled-trial-100539771","NCT06308172","Impact of Single- Versus Double-layer Hysterotomy Closure on Cesarean Niche Development: a Randomized Controlled Trial","Inclusion Criteria:\n\n* nulliparous\n* singleton\n* age 18-45\n* spontaneous pregnancy or autologous assisted fertilization\n* gestational age 38-40 weeks\n* elective C-section\n* informed consent\n\nExclusion Criteria:\n\n* coagulopathy\n* autoimmune diseases\n* gestational diabetes\n* anticoagulant therapy\n* immunosuppressive therapy\n* endometriosis\n* uterine fibromatosis\n* spontaneous labour\n* connective tissue diseases",{"count":51,"type":20},150,[23],"The objective of this randomized monocentric study is to assess potential variations in the incidence and severity of isthmocele morbidity among women undergoing cesarean section with either single or double-layer closure of the hysterotomy. Our primary outcome aims to investigate whether there is a reduction in the median duration of intermenstrual spotting in patients belonging to the two respective closure groups",[26,55,56,57,58],"Uterine Bleeding","Uterus; Scar","Uterus Abnormal","Cesarean Section Complications","2024-03-06",{"date":61,"type":35},"2024-03-13",{"date":63,"type":35},"2021-12-01",{"date":65,"type":20},"2026-12-01",{"name":67,"class":42},"Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico"]