[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"charcot-marie-tooth-disease-type-ia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:charcot-marie-tooth-disease-type-ia":124},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100640793","physical-activity-level-at-home-in-cmt1a-patients-wearable-sensor-assessment-100640793",false,"NCT07591779","Physical Activity Level at Home in CMT1A Patients: Wearable Sensor Assessment","Study of the Relationship Between Clinical and Functional Characteristics of Patients With CMT1A Disease and Their Level of Physical Activity at Home Measured Using Portable Electronic Sensors","CMT1A-HOME","Inclusion Criteria:\n\n1. Age ≥ 18 years\n2. Genetically confirmed diagnosis of CMT1A (PMP22 duplication on chromosomal analysis)\n3. Followed at the National Reference Centre for Rare Peripheral Neuropathies (Service de Neurologie, CHU de Limoges) and\u002For having undergone gait analysis at the Quantified Movement Analysis Laboratory (Laboratoire d'AQM), Service de Médecine Physique et de Réadaptation, CHU de Limoges\n4. Ability to walk independently (with or without walking aids)\n5. Informed consent obtained\n6. Affiliated to French social security system\n\nExclusion Criteria:\n\n1. Other associated neurological condition that could independently affect walking or motor activity\n2. Inability to wear the sensor device (skin allergy, sensory intolerance)\n3. Inability to comply with study procedures (cognitive impairment, no fixed domicile)\n4. Participation in another interventional study during the same period\n5. Pregnant or breastfeeding women\n6. Patients under legal protection (guardianship or curatorship)","ALL","18 Years",{"count":20,"type":21},60,"ESTIMATED","OBSERVATIONAL","Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common hereditary peripheral neuropathy, affecting approximately 26,000 patients in France. It presents as chronic and progressive sensorimotor deficits predominantly affecting the distal lower limbs, with onset typically in childhood. There is currently no specific pharmacological treatment; management remains symptomatic.\n\nThis research will:\n\nIn the long run, validated wearable sensors could improve patient follow-up, personalize rehabilitation, and support the design of clinical trials for CMT1A - including trials of the novel \"Nano-Cur\" treatment currently under development.",[25,26,27,28,29],"Charcot-Marie-Tooth Disease, Type IA","Peripheral Neuropathy Hereditary","Motor Activity","Walking, Difficulty","Neuromuscular Diseases",[31,32,33,34,35,36,37],"CMT1A","wearable sensor","actigraphy","physical activity","CMT-FOM","functional assessment","peripheral neuropathy","NOT_YET_RECRUITING","2026-05-20",{"date":41,"type":42},"2026-05-22","ACTUAL",{"date":44,"type":21},"2026-06-01",{"date":46,"type":21},"2027-06-30",{"name":48,"class":49},"University Hospital, Limoges","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":60,"conditions":61,"keywords":109,"overallStatus":113,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":50},"100508586","natural-history-study-for-charcot-marie-tooth-disease-100508586","NCT05902351","Natural History Study for Charcot Marie Tooth Disease","Global Registry for Inherited Neuropathies Natural History Study for Charcot Marie Tooth Disease","Inclusion Criteria:\n\nPatients will be made aware of the study by HNF and others (referenced above) and invited to participate. Once patients have reviewed and signed electronically the informed consent document, it is attached to their file.\n\nAll affected individuals with CMT\u002FIN are eligible to participate in GRIN with proper informed consent.\n\nChildren, adolescents and adults with either a confirmed diagnosis or suspected to have CMT\u002FIN are eligible with parent and\u002For guardian consent.\n\nIndividuals that have been clinically diagnosed through family history and\u002For standard clinical testing (e.g. neuro exam, EMG, NCS) and\u002For genetically tested or suspected to have CMT\u002FIN (note: many mutations have not been identified yet) are eligible.\n\nExclusion Criteria:\n\nPeople that do not have Charcot-Marie-Tooth or other Inherited Neuropathies",{"count":59,"type":21},10000,"The goal of this Natural History Study for Charcot-Marie-Tooth is to acquire, record, and analyze patient-reported data and associated genetic reports, Electronic Health Records (EHRs) and clinical notes to identify the burden, diagnostic journey, and prevalence of disease that will aid scientists in their work toward finding a cure.\n\nParticipants will be asked to complete a Natural History Survey.",[62,63,25,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97,98,99,100,101,102,103,104,105,106,107,108],"Charcot-Marie-Tooth Disease","Charcot-Marie-Tooth","Charcot-Marie-Tooth Disease Type 2A","Charcot-Marie-Tooth Disease Type 2","Charcot-Marie-Tooth Disease, Type 2C","Charcot-Marie-Tooth Disease Type 2A2B","Charcot-Marie-Tooth Disease Type 2B2","Charcot-Marie-Tooth Disease Type 2A1","Charcot-Marie-Tooth Disease Type 4B1","Charcot-Marie-Tooth Disease, Type IB","Charcot-Marie-Tooth Disease Type 2B1","Charcot-Marie-Tooth Disease Type 2U (Diagnosis)","Charcot-Marie-Tooth Disease Type 4A","Charcot-Marie-Tooth Disease, Type 4A, Axonal Form","Charcot-Marie-Tooth Disease Type 2A2A","Charcot-Marie-Tooth Disease Type 2S (Disorder)","Charcot-Marie-Tooth Disease and Deafness","Charcot-Marie-Tooth Disease Type 4B2","Charcot-Marie-Tooth Disease Type 4H","Charcot-Marie-Tooth Disease Type 1F","Charcot-Marie-Tooth Disease Type 4C","Charcot-Marie-Tooth Disease Type 4E","Charcot-Marie-Tooth Disease Type 1D","Charcot-Marie-Tooth Disease Type 2Q (Diagnosis)","Charcot-Marie-Tooth Disease Type 2A2","Charcot-Marie-Tooth Disease Type 2N (Diagnosis)","Charcot-Marie-Tooth Disease Type 2B5","Charcot-Marie-Tooth Disease Type 2D","Charcot-Marie-Tooth Disease Type 4D","Charcot-Marie-Tooth Disease Type 2K","Charcot-Marie-Tooth Disease Type 2L (Diagnosis)","Charcot-Marie-Tooth Disease Type 2T","Charcot-Marie-Tooth Disease Type 2I","Charcot-Marie-Tooth Disease Type 2J","Charcot-Marie-Tooth Disease Type 2E","Charcot-Marie-Tooth Disease Type 2G","Charcot-Marie-Tooth Disease Type 1C","Charcot-Marie-Tooth Disease Type 2R","Charcot-Marie-Tooth Disease Type 2O (Diagnosis)","Charcot-Marie-Tooth Disease Type 2M","Charcot-Marie-Tooth Disease Type 2P","Charcot-Marie-Tooth Disease Type 2Y","Charcot-Marie-Tooth Disease Type 4F (Diagnosis)","Charcot-Marie-Tooth Disease Type 4B3","Charcot-Marie-Tooth Disease Type 2H","HNPP","X-Linked Charcot-Marie-Tooth Disease",[110,111,63,62,112],"Inherited Neuropathies","Peripheral Neuropathy","CMT","RECRUITING","2024-09-30",{"date":116,"type":42},"2024-10-01",{"date":118,"type":42},"2013-11-01",{"date":120,"type":21},"2029-12-31",{"name":122,"class":123},"Hereditary Neuropathy Foundation","OTHER_GOV","Charcot-Marie-Tooth Disease, Type Ia"]