[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"childhood-asthma\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:childhood-asthma":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,47,75,100,126],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100545940","asthma-link-effectiveness-trial-100545940",false,"NCT06388460","Asthma Link Effectiveness Trial","Asthma Link: A Partnership Between Pediatric Practices, Schools, and Families to Improve Medication Adherence and Health Outcomes in Children With Poorly Controlled Asthma","STUDY INCLUSION\u002FEXCLUSION CRITERIA:\n\nChild Inclusion Criteria:\n\n* Meet the eligibility criteria for Asthma Link (as described below)\n* Enrolled in Asthma Link (if randomized to the Asthma Link Condition)\n* Able and willing to provide informed assent\n\nChild Exclusion Criteria:\n\n* Unable or unwilling to provide informed assent\n* Developmental delay that would prevent study participation.\n\nParent Inclusion Criteria:\n\n* Parent\u002Fguardian to patient\n* 18 years or older\n* Able to understand and communicate in English or Spanish\n* Able and willing to provide informed consent.\n\nChild eligibility for children enrolled in Asthma Link:\n\n* children aged 5-14 years (enrolled in grade K-8)\n* prescribed daily inhaled corticosteroid (ICS) for asthma\n* Asthma Control Test (ACT) score ≤19 OR 1 or more of ANY of following in the past 1 year: course of oral steroids, hospitalization, Emergency Department visit, sick visit for asthma\n* parent\u002Fchild report of poor ICS adherence on adherence checklist- i.e. child or parent says \"Yes\" when provider asks if they have difficulty remembering to take their medication or if they regularly take medication holidays or breaks\n* able and willing to assent\n* parental permission\n* English or Spanish speaking","ALL","5 Years","14 Years",{"count":20,"type":21},350,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this cluster Randomized Control Trial is to determine the effectiveness of Asthma Link, a school supervised asthma therapy program, compared with an educational asthma workbook, in improving asthma symptoms for children with poorly controlled asthma aged 5-14.",[27],"Childhood Asthma",[29,30,31,32,33],"asthma","childhood asthma","medication adherence","school-supervised asthma therapy","real-world","RECRUITING","2026-04-30",{"date":37,"type":38},"2026-05-05","ACTUAL",{"date":40,"type":38},"2024-04-04",{"date":42,"type":21},"2028-04",{"name":44,"class":45},"University of Massachusetts, Worcester","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":64,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":71,"leadSponsor":73,"locationsCount":46},"100613041","pollution-intervention-to-impact-kids-asthma-study-100613041","NCT07261423","Pollution Intervention to Impact Kids Asthma Study","PIKAS","Inclusion Criteria:\n\n* A healthcare provider diagnosis of persistent asthma (Steps 2-5 as defined by US guidelines) or intermittent asthma (Step 1) + at least one severe asthma exacerbation (defined by American Thoracic Society (ATS)\u002FEuropean Respiratory Society (ERS) criteria as requiring at least 3 days of systemic steroids or an Emergency Department\u002FUrgent Care visit requiring systemic steroids) in the prior 12 months\n* Home access to a smartphone or internet\n* Primary residence in Allegheny County, PA\n* One participant per household\n* Age 8 -17 years\n* Healthcare provider evaluation for asthma in the prior year\n\nExclusion Criteria:\n\n* Diagnosis of other active chronic respiratory diseases (e.g., cystic fibrosis, bronchopulmonary dysplasia, etc.)\n* Neuromuscular disorder\n* Chronic disorder limiting independent ambulation (e.g., spastic quadriplegia, etc.)\n* Cyanotic heart disease\n* Plans to relocate from Allegheny County, PA in the next year (12 months)\n* Use of intranasal or oral\u002Fintramuscular\u002Fintravenous corticosteroids 4 weeks prior to randomization\n* Current participation in another asthma intervention trial","8 Years","17 Years",{"count":57,"type":21},351,[24],"The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children. It will also learn about children with asthma who report being more sensitive to outdoor air pollution. The main questions it aims to answer are:\n\n* Does adding either information about the EPA-AQI or commercial AQI improve asthma outcomes over time?\n* Are there changes in nasal gene expression in children with asthma who report they are more sensitive to outdoor air pollution?\n\nResearchers will compare EPA-AQI and the commercial-AQI groups to a control group to either AQI works to improve asthma.\n\nParticipants will:\n\n* Receive standardized outdoor air pollution education and an asthma action plan\n* Provide nose and blood specimens\n* Have visits every 4 weeks for 48 weeks, 10 will be conducted by telephone calls and 3 visits will be in person.",[27,61,62,63],"Asthma Control","Asthma Exacerbation","Air Pollution, Risk Reduction Behaviors",[30,65,66],"air quality index","AQI","2026-02-24",{"date":69,"type":38},"2026-02-27",{"date":67,"type":38},{"date":72,"type":21},"2030-01",{"name":74,"class":45},"University of Pittsburgh",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":81,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":46},"100621376","optimization-and-testing-of-alrite-a-clinical-decision-support-tool-for-management-of-respiratory-illnesses-in-young-children-in-primary-care-health-facilities-in-uganda-100621376","NCT07369817","Optimization and Testing of ALRITE, a Clinical Decision Support Tool for Management of Respiratory Illnesses in Young Children in Primary Care Health Facilities in Uganda","Inclusion Criteria:\n\n* Healthcare workers employed at each study site with a minimum of 6 months' experience of caring for children with respiratory symptoms in general outpatient care\n* Completed one of the following training programs: medical officer, clinical officer, nurse, midwife\n* proficient in reading and speaking English, one of the official languages of Uganda\n* at least 18 years of age\n\nExclusion Criteria:\n\n* inability to read\u002Fwrite English","18 Years",{"count":83,"type":21},48,[24],"The goal of this study is to pilot test the feasibility of a mobile health clinical decision support tool called ALRITE for the diagnosis and management of acute lower respiratory illnesses in young children in Uganda. Asthma\u002Fwheezing illness, in particular, is underdiagnosed in this setting. The main questions the study aims to answer are:\n\n* Are the intervention structure, processes, outcomes, and implementations strategies feasible to conduct in the desired settings?\n* Does ALRITE increase the diagnosis of wheezing illness among children seen at Ugandan health centers?\n\nResearchers will compare outcomes before and after ALRITE deployment to healthcare workers at 4 Ugandan healthcare centers using an interrupted time series design. Study participants are healthcare workers.\n\nThere will be12 months of baseline data collection (\"baseline period\"), at the beginning of which healthcare workers will be enrolled at each site. Following the baseline period, health workers will receive ALRITE training and will be encouraged but not required to use ALRITE in clinical care for a 6-month intervention period. Health worker participants will fill out surveys and participate in focus group discussions to provide feedback.",[87,27,88,89],"Pneumonia Childhood","Acute Lower Respiratory Illness","Wheezing Lower Respiratory Illness","NOT_YET_RECRUITING","2026-01-23",{"date":93,"type":38},"2026-01-27",{"date":95,"type":21},"2026-02-01",{"date":97,"type":21},"2027-11-30",{"name":99,"class":45},"University of Washington",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":11,"sex":16,"minAge":107,"maxAge":108,"enrollmentInfo":109,"targetDuration":4,"studyType":22,"phases":111,"briefSummary":112,"conditions":113,"keywords":4,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":46},"100590969","effect-of-multimedia-protocol-about-asthma-control-100590969","NCT06974331","Effect of Multimedia Protocol About Asthma Control","Effect of Multimedia Protocol About Asthma Control on Asthmatic Children's Adaptation in the Era of Climate Changes","Inclusion Criteria:\n\n* Chronic asthmatic children (aged 7-11 years).\n* Both urban and rural asthmatic children.\n* Children and their mothers who have not received current or prior guidance about asthma control with the repercussions of climate changes.\n* Children whose mothers is educated.\n\nExclusion Criteria:\n\n* \\- Children with severe or acute asthma attacks as confirmed by a medical practitioner.\n* Any child suffering from other chronic disease or disability, as confirmed by a medical practitioner.","7 Years","11 Years",{"count":110,"type":21},70,[24],"This study aims to evaluate the effect of multimedia protocol about asthma control on asthmatic children's adaptation in the era of climate changes.",[114,27,115,116],"Bronchial Asthma","Climate Change","Multimedia Learning Education","2025-05-08",{"date":119,"type":38},"2025-05-15",{"date":121,"type":21},"2025-07-01",{"date":123,"type":21},"2026-09-01",{"name":125,"class":45},"Mansoura University",{"id":127,"slug":128,"hasResults":11,"nctId":129,"briefTitle":130,"officialTitle":130,"acronym":131,"eligibilityCriteria":132,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":133,"enrollmentInfo":134,"targetDuration":136,"studyType":137,"phases":4,"briefSummary":138,"conditions":139,"keywords":4,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":4},"100447357","the-impact-of-synergies-of-indoor-air-pollutants-on-childhood-health-and-wellbeing-100447357","NCT05105386","The Impact of Synergies of Indoor Air Pollutants on Childhood Health and Wellbeing","SynAir-Child","Inclusion Criteria:\n\n1. Students of primary schools aged 8-9 years.\n2. The subject and\u002For legal custodian have the verbal, writing and mental ability to understand the intent and character of the study.\n3. Written informed consent from the child's parents\u002Fguardian's\n\nExclusion Criteria:\n\nUnwilling to use the application and follow the procedures of the protocol","9 Years",{"count":135,"type":21},3000,"1 Year","OBSERVATIONAL","To quantify health effects of synergizing chemical and biological pollutants in a targeted population setting, i.e., school-aged children. Indoor air pollutants will be monitored within the classrooms with high end sensors. Exposure data from additional sources (outdoor, home, transports) will be obtained. Health outcomes will be assessed prospectively using validated medical procedures and real-time tracking with mobile health (mHealth) equipment and a gamified computer app.",[140,141,27,142],"Pollution; Exposure","Environmental Exposure","Childhood","2021-10-22",{"date":145,"type":38},"2021-11-03",{"date":147,"type":21},"2023-09",{"date":149,"type":21},"2027-09",{"name":151,"class":45},"National and Kapodistrian University of Athens"]