[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"childhood-cancers\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:childhood-cancers":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100614347","assessing-and-addressing-health-related-social-needs-among-families-of-children-with-cancer-100614347",false,"NCT07278414","Assessing and Addressing Health-Related Social Needs Among Families of Children With Cancer","Developing and Refining an Intervention to Assess and Address Health-Related Social Needs Among Families of Children With Cancer","Inclusion Criteria:\n\nCaregivers of Children with Cancer\n\n* A caregiver of a child (\\\u003C18 years old) actively receiving treatment or recently completed treatment (within the past 1 year prior to enrollment) for any type of cancer. A caregiver is defined as any individual involved in bringing the child to the clinic or providing care at home, the hospital, or other healthcare setting (e.g., parents, guardians, siblings, etc.).\n* Ability to understand IRB-approved information sheet and willingness to provide consent.\n* Age ≥ 18 years at the time of consent.\n* Ability to understand the English and\u002For Spanish language.\n\nCommunity-based Organizations\n\n* Representative of community-based organizations that provide resources for families of children with cancer\n* Ability to understand IRB-approved information sheet and willingness to provide consent.\n* Age ≥ 18 years at the time of consent.\n* Ability to understand English and\u002For Spanish language.\n\nHealthcare Professionals\n\n* Physicians, advanced practice practitioners, nurses, clinical social workers, medical assistants, clinic patient service representatives, and cancer center administrators at AHWFBC.\n* Ability to understand IRB-approved information sheet and willingness to provide consent.\n* Age ≥ 18 years at the time of consent.\n* Ability to understand English and\u002For Spanish language.\n\nExclusion Criteria:\n\n* There are no specific exclusion criteria.",true,"ALL","18 Years",{"count":20,"type":21},60,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to design Community Enhancing Resources for Childhood cAncer support (CERCA) and refine intervention procedures to target Health-related Social Needs (HRSN) in families of children with cancer. CERCA will leverage existing community resources and create partnerships that will lead to sustainable outcomes. The hypothesis is that through context-driven co-design and community-engaged research methods, the study team will develop an acceptable intervention to target unmet HRSN in families of children with cancer.",[25,26,27,28],"Childhood Cancers","Caregiver Social Support","Caregiver Distress","Social Needs",[28,30,31],"Caregiver Support","Childhood Cancer","RECRUITING","2026-04-27",{"date":35,"type":36},"2026-05-04","ACTUAL",{"date":38,"type":36},"2026-01-07",{"date":40,"type":21},"2027-06",{"name":42,"class":43},"Wake Forest University Health Sciences","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":52,"targetDuration":54,"studyType":22,"phases":4,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":4},"100616645","examination-of-the-relationship-between-quality-of-life-and-caregiving-burden-among-caregivers-of-pediatric-oncology-patients-100616645","NCT07308301","Examination of the Relationship Between Quality of Life and Caregiving Burden Among Caregivers of Pediatric Oncology Patients","EXAMİNATİON OF THE RELATİONSHİP BETWEEN QUALİTY OF LİFE AND CAREGİVİNG BURDEN AMONG CAREGİVERS OF PEDİATRİC OCOLOGY PATİENTS","Inclusion Criteria:\n\n* Being a family member who provides care for a child aged 0-18 years diagnosed with cancer\n* The child being in the active treatment phase (chemotherapy, radiotherapy, post-surgical follow-up, etc.)\n* Being able to read and write in Turkish and having sufficient literacy to complete the research questionnaire\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Not being the primary caregiver of the child (serving only as a short-term companion)\n* Being unable to complete the questionnaire due to a psychiatric diagnosis or communication difficulties\n* The child having a disability",{"count":53,"type":21},95,"4 Months","Primary Aim\n\nThe primary aim of this study is to determine the quality of life and caregiving burden levels of caregivers of pediatric oncology patients and to examine the relationship between these two variables.\n\nSecondary Aims\n\nTo evaluate the differences between caregivers' sociodemographic characteristics (age, gender, education level, marital status, income level, etc.) and their quality of life.\n\nTo examine the differences between caregivers' sociodemographic characteristics and their caregiving burden levels.\n\nTo determine whether caregivers' quality of life and caregiving burden differ according to the diagnosis and treatment characteristics of pediatric oncology patients (duration of diagnosis, type of treatment, frequency of hospitalization, etc.).\n\nSignificance of the Study\n\nChildhood cancer is a process that deeply affects not only the patient but also the family, particularly the caregivers. Family members who provide care for children often face intense physical, psychological, social, and economic burdens. These challenges reduce caregivers' quality of life and increase their caregiving burden.\n\nIdentifying the relationship between the quality of life and caregiving burden among caregivers of pediatric oncology patients is highly important in planning support services for families during the care process and in strengthening family-centered care practices by healthcare professionals.\n\nThe findings of this study will contribute to the development of family-centered approaches in nursing care, the design of psychosocial support programs, and a better understanding of caregivers' needs.",[31,25,57,58,59,60,61],"Caregiver Subjective Burden","Primary Caregivers of Children Newly Diagnosed With Cancer","Caregiver","Caregiver Anxiety","Caregiver Health Related QOL","NOT_YET_RECRUITING","2025-12-26",{"date":65,"type":36},"2025-12-31",{"date":67,"type":21},"2026-01-01",{"date":69,"type":21},"2026-06-30",{"name":71,"class":43},"Fatma Beyza Akdeniz",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":17,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":83,"conditions":84,"keywords":91,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":111},"100611871","caya-cancer-retrospective-cohort-study-100611871","NCT07246213","CAYA Cancer Retrospective Cohort Study","Improving Cancer Outcomes for Children, Adolescents, and Young Adults: A Multicenter Retrospective Cohort Study on Treatment Failure and Toxicity in Low- and Middle-Income Countries","Inclusion Criteria:\n\nSubjects must meet all the following criteria to be included in this registry:\n\n1. Participants must be willing and able to provide informed consent prior to enrollment in the registry.\n\n   1. For minors or individuals unable to provide informed consent, assent must be obtained along with consent from a legal guardian.\n   2. Note: Exemption applies to this criterion when waiver of informed consent\u002Fassent is granted by Institutional Review Board(IRB)\u002FIndependent Ethics Committee(IEC)\u002FCompetent Authorities(CAs).\n2. A confirmed diagnosis of any type of cancer within the 15 years prior to the site's activation date.\n3. Age 0 to 21 years at the time of diagnosis.\n4. Received substantial anti-cancer treatment at the participating center, including but not limited to:\n\n   1. Chemotherapy\n   2. Surgery\n   3. Radiation therapy\n   4. Immunotherapy\n5. Medical records are available and accessible for review\n\nExclusion Criteria:\n\n* Subjects meeting any of the following criteria will be excluded from this registry:\n\n  1. Patients who only visited the participating center for:\n\n     1. Consultation without subsequent primary anti-cancer treatment at the participating center\n     2. Pathology, radiology, or other diagnostic evaluations without treatment","0 Years","21 Years",{"count":82,"type":21},18000,"Despite advances in cancer treatment, significant disparities in outcomes persist between high-income countries (HICs) and low-and middle-income countries (LMICs). Around 80% of children with cancer live in LMICs, where they face challenges such as delayed diagnosis, misdiagnosis, comorbidities, distance to treatment, financial barriers, and limited access to risk-adapted therapies.\n\nAcute lymphoblastic leukemia(ALL)\u002Flymphoblastic lymphoma(LBL), for example, is one of the greatest success stories in pediatric oncology, however, such improvements are not evenly distributed worldwide, and the outcomes for leukemia patients are poorer in LMICs compared to HICs, primarily due to reduced access to quality healthcare.\n\nThis study aims to assess cancer treatment outcomes in LMICs, focusing on acute lymphoblastic leukemia\u002Flymphoblastic lymphoma. The findings will inform future studies to implement evidence-based interventions that improve care quality and reduce treatment failures through targeted strategies.",[85,86,87,88,25,89,90],"Acute Lymphoblastic Leukemia","Lymphoblastic Lymphoma","Young Adult Cancer","Adolescent Cancer","Acute Lymphoblastic Leukemia (ALL)","Lymphoblastic Lymphoma (LBL)",[92,93,94,95,96,97,98,99,100,101],"Cancer outcomes","Low- and Middle-Income Countries (LMICs)","Childhood cancer","Adolescent and young adult cancer (CAYA)","Treatment failure","Therapy-related toxicities","Retrospective cohort","Leukemia outcomes","Oncology disparities","High-Income Countries (HICs)","2025-12-12",{"date":104,"type":36},"2025-12-19",{"date":106,"type":36},"2025-06-04",{"date":108,"type":21},"2028-12-04",{"name":110,"class":43},"Resonance, Inc.",5]