[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"choledochal-cyst\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:choledochal-cyst":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,44,71,95,115],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100583797","biliary-dilatation-national-special-disease-cohort-in-china-100583797",false,"NCT06881004","Biliary Dilatation National Special Disease Cohort in China","Establishment and Evaluation of Clinical Classification and Surgical Decision-making System for Biliary Dilatation：a National Special Disease Cohort Study in China","Inclusion Criteria:\n\n1. Patients who have been definitive diagnosed with biliary dilation.\n2. Patients aged between 0 and 80 years old, regardless of gender.\n3. In line with the principle of informed consent: For the retrospective cohort of biliary dilation, exemption from signing the informed consent form is applied for, while for the prospective cohort, signing the informed consent form is required.\n\nExclusion Criteria:\n\n* None","ALL","80 Years",{"count":19,"type":20},6000,"ESTIMATED","OBSERVATIONAL","This study is a multicenter, bidirectional cohort study aimed at continuously enrolling patients with biliary dilatation from 25 medical centers in China. It will collect comprehensive life-cycle data from the cohort to establish a Chinese cohort for bile duct dilatation. Based on this cohort, the study seeks to clarify the epidemiological characteristics, pathological features, standard classification, disease progression, cancer risk, and optimal timing for surgical intervention in patients with bile duct dilatation. Additionally, it will compare the perioperative risks, long-term outcomes, and quality of life among different types of patients (including Todani types I, IVa, and V) following surgical treatment, to establish standardized surgical treatment strategies for each type.",[24],"Choledochal Cyst",[26,27,28,29,30],"Biliary dilatation","Cohort study","Clinical database","Surgical treatment","Long-term outcome","RECRUITING","2026-06-22",{"date":34,"type":35},"2026-06-23","ACTUAL",{"date":37,"type":35},"2025-03-19",{"date":39,"type":20},"2035-03-31",{"name":41,"class":42},"Beijing Tsinghua Chang Gung Hospital","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":16,"minAge":4,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":54,"conditions":55,"keywords":56,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":70},"100633720","a-longitudinal-cohort-study-on-the-changes-of-physiological-mechanisms-in-children-after-biliary-tract-reconstruction-100633720","NCT07530354","A Longitudinal Cohort Study on the Changes of Physiological Mechanisms in Children After Biliary Tract Reconstruction","Inclusion Criteria:\n\n* Healthy children matched by age and gender were selected as the control group\n\nExclusion Criteria:\n\n* Combined with other serious diseases (such as cancer, autoimmune diseases), having obvious liver function abnormalities before surgery or being undergoing other major treatments.",true,"16 Years",{"count":53,"type":20},100,"Through observational studies, the long-term changes in liver function, metabolic state, immune response and other aspects of children after biliary tract reconstruction during their growth process were systematically explored. The risks of these long-term physiological changes on chronic diseases such as cardiovascular diseases, diabetic diseases and liver cirrhosis in adulthood, as well as their impacts on cognitive function, musculoskeletal health and other aspects were evaluated. How do early physiological changes affect a patient's long-term health? Are there any potential biomarkers that can predict future health outcomes? Based on the research results, preventive and intervention measures that are helpful in reducing the risk of long-term complications are proposed.",[24],[24,57,58,59,60],"Cholecystectomy","Cohort Studies","Treatment Outcome","Surgical Procedures","2026-04-07",{"date":63,"type":35},"2026-04-15",{"date":65,"type":35},"2025-05-01",{"date":67,"type":20},"2035-04-30",{"name":69,"class":42},"Wuhan Children's Hospital",3,{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":50,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":80,"conditions":81,"keywords":82,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":43},"100604667","host-microbe-interactions-in-biliary-dilatation-100604667","NCT07152496","Host-Microbe Interactions in Biliary Dilatation","Integrated Transcriptome-Microbiome Profiling Reveals Host-Microbe Crosstalk in Biliary Dilatation","Inclusion Criteria:\n\nPatients who have been definitively diagnosed with biliary dilatation and are scheduled for surgical resection (Disease group) Healthy donor bile duct tissues discarded during organ transplantation procedures as part of routine surgical preparation (Control group)\n\nExclusion Criteria:\n\nPatients with severe systemic diseases that may affect study outcomes (Disease group) Insufficient tissue sample quality or quantity (Disease group) Unavailable or inadequate donor bile duct tissue samples (Control group)",{"count":79,"type":20},400,"This study is an observational cohort study aimed at continuously enrolling patients with biliary dilatation and healthy controls. It will collect bile duct tissue samples and clinical data from participants across all age groups to establish a comprehensive cohort for biliary dilatation research. Based on this cohort, the study seeks to investigate the molecular mechanisms underlying biliary dilatation development and progression, explore the role of host-microbiome interactions in disease processes, and identify biomarkers associated with complications and malignancy risk, to establish evidence-based strategies for improved diagnosis and treatment of biliary dilatation.",[24],[83,84,85],"molecular mechanism","Biliary Dilatation","microbiome","NOT_YET_RECRUITING","2025-12-07",{"date":89,"type":35},"2025-12-09",{"date":91,"type":20},"2025-12-15",{"date":93,"type":20},"2026-07-01",{"name":41,"class":42},{"id":96,"slug":97,"hasResults":11,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":4,"eligibilityCriteria":101,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":17,"enrollmentInfo":102,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":104,"conditions":105,"keywords":106,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":111,"completionDateStruct":112,"leadSponsor":114,"locationsCount":43},"100595776","efficacy-and-safety-of-surgical-treatment-for-type-iva-cbd-100595776","NCT07036848","Efficacy and Safety of Surgical Treatment for Type IVa CBD","The Efficacy and Safety of Surgical Treatment in Type IVa Congenital Biliary Dilation: A Multi-center Cohort Study","Inclusion Criteria:\n\n1. Patients who have been diagnosed with Todani type IVa BD.\n2. Patients aged between 0 and 80 years old, regardless of gender.\n3. First-time receipt of surgery.\n\nExclusion Criteria:\n\n1. With abnormal intrapancreatic bile duct\n2. Inappropriate Roux-loop length (outside the range of 40-60 cm for adults and 15-30 cm for children)\n3. With non-relevant surgical interventions\n4. Pathologically confirmed carcinogenesis\n5. Unresolved choledocholithiasis, bile duct stenosis, and Intrahepatic bile duct stones during the procedure.\n6. Unavailable follow-up information.",{"count":103,"type":20},1500,"This study is a multicenter, bidirectional cohort study aimed at continuously enrolling patients with biliary dilatation from 25 medical centers in China. It will collect comprehensive life-cycle data from the cohort to establish a Chinese cohort for IVa biliary dilatation (BD). Based on this cohort, the study seeks to compare the perioperative risks, long-term outcomes, and quality of life of type IVa BD following surgical treatment, to establish standardized surgical treatment strategies for type IVa BD.",[24],[107],"Biliary Dilatation, Cohort Study, Surgical Treatment","2025-07-14",{"date":110,"type":35},"2025-07-17",{"date":108,"type":35},{"date":113,"type":20},"2035-07-01",{"name":41,"class":42},{"id":116,"slug":117,"hasResults":11,"nctId":118,"briefTitle":119,"officialTitle":120,"acronym":121,"eligibilityCriteria":122,"healthyVolunteers":11,"sex":16,"minAge":123,"maxAge":124,"enrollmentInfo":125,"targetDuration":4,"studyType":127,"phases":128,"briefSummary":130,"conditions":131,"keywords":4,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":4},"100486931","timing-of-operation-in-children-with-a-prenatal-diagnosis-of-choledochal-cyst-100486931","NCT05620485","Timing of Operation in Children With a Prenatal Diagnosis of Choledochal Cyst","Timing of Operation in Children With a Prenatal Diagnosis of Choledochal Cyst：A Single-center Prospective Study","CDCPS","Inclusion Criteria:\n\n1. Infants with a prenatal and postnatal diagnosis with CDC\n2. Prenatal and postnatal hepatobiliary ultrasound data were complete\n3. Age of visit \\\u003C 3 months\n\nExclusion Criteria:\n\nUnable to tolerate surgery after birth","0 Months","3 Months",{"count":126,"type":20},30,"INTERVENTIONAL",[129],"NA","In this prospective study, we tried to select the operation time according to the cyst size and evaluate the treatment effect.",[24],"2022-11-12",{"date":134,"type":35},"2022-11-17",{"date":136,"type":20},"2022-11-15",{"date":138,"type":20},"2026-11-15",{"name":140,"class":42},"Guangzhou Women and Children's Medical Center"]