[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"choledocholithiasis-with-cholecystitis-with-obstruction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:choledocholithiasis-with-cholecystitis-with-obstruction":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":5},"100642549","supraglottic-oxygenation-via-oral-transtracheal-catheter-for-reducing-the-incidence-of-hypoxemia-during-ercp-under-sedation-100642549",false,"NCT07637721","Supraglottic Oxygenation Via Oral Transtracheal Catheter for Reducing the Incidence of Hypoxemia During ERCP Under Sedation","Supraglottic Oxygenation Via Oral Transtracheal Catheter for Reducing the Incidence of Hypoxemia During ERCP Under Sedation：a Randomized Controlled Trial","Inclusion Criteria:\n\n* Age≥18years\n* The ASA classification ranges from I to III\n* Patients have signed the informed consent form\n* Patients scheduled to undergo sedated ERCP examination procedure\n\nExclusion Criteria:\n\n* Severe cardiac dysfunction (\\\u003C4 METs);\n* Diagnosed chronic obstructive pulmonary disease (COPD) or other acute\u002Fchronic pulmonary diseases requiring long-term\u002Fintermittent oxygen therapy;\n* Upper respiratory tract infections including oral, nasal or pharyngeal infections;\n* Fever (core temperature \\>37.5°C);\n* Confirmed pregnancy or current breastfeeding;\n* Hypersensitivity to sedative drugs such as propofol;\n* Current participation in other clinical trials;","ALL","18 Years",{"count":19,"type":20},410,"ESTIMATED","INTERVENTIONAL",[23],"NA","Endoscopic retrograde cholangiopancreatography (ERCP) is commonly used for the diagnosis and treatment of pancreatobiliary diseases. While Monitored Anesthesia Care (MAC) enhances the efficiency of ERCP, deep sedation introduces significant airway risks, particularly hypoxemia resulting from sedative-induced upper airway collapse. With reported hypoxemia rates ranging from 10% to 69%, and the potential for severe complications such as myocardial ischemia and neurological damage, effective airway management is paramount. Supraglottic oxygenation via oral transtracheal catheter provides a viable method for relieving obstruction and enabling positive pressure ventilation, serving as a less invasive alternative to tracheal intubation. Despite its proven utility in other settings, this technique has not yet been evaluated in the context of deeply sedated ERCP.",[26,27,28,29],"Choledocholithiasis With Cholecystitis With Obstruction","Obstructive Jaundice","Pancreatitis","Cholelithiasis",[31,32,33,34,35],"ERCP","Monitored Anesthesia Care","deep sedation","hypoxemia","The Supraglottic Oxygenation Via Oral Transtracheal Catheter","NOT_YET_RECRUITING","2026-06-09",{"date":39,"type":40},"2026-06-10","ACTUAL",{"date":42,"type":20},"2026-06-12",{"date":44,"type":20},"2027-12-31",{"name":46,"class":47},"Zhejiang University","OTHER",{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},"100596938","phase-2-feasibility-and-safety-of-supraglottic-oxygen-delivery-via-an-endotracheal-tube-for-non-intubated-ercp-anesthesia-a-two-stage-phase-ii-clinical-study-100596938","NCT07051980","Feasibility and Safety of Supraglottic Oxygen Delivery Via an Endotracheal Tube for Non-intubated ERCP Anesthesia: A Two-Stage Phase II Clinical Study","Inclusion Criteria:\n\n* Age ≥18 years；\n* The ASA classification ranges from I to III.\n* Patients have signed the informed consent form.\n* Patients scheduled to undergo sedated ERCP examination;\n* The estimated duration of the procedure does not exceed 45 minutes.\n\nExclusion Criteria:\n\n* Severe cardiac dysfunction (\\\u003C4 METs);\n* Severe renal insufficiency (requiring preoperative dialysis);\n* Diagnosed chronic obstructive pulmonary disease (COPD) or other acute\u002Fchronic pulmonary diseases requiring long-term\u002Fintermittent oxygen therapy;\n* Increased intracranial pressure;\n* Upper respiratory tract infections (oral\u002Fnasal\u002Fpharyngeal);\n* Fever (core temperature \\>37.5°C);\n* Confirmed pregnancy or current breastfeeding;\n* Allergy to sedatives (e.g., propofol) or medical adhesives;\n* BMI \\>30 kg\u002Fm²;\n* Current participation in other clinical trials;",{"count":55,"type":20},50,[57],"PHASE2","Endoscopic retrograde cholangiopancreatography (ERCP) is a technique for evaluating the bile duct, pancreatic duct, and ampulla. Hypoxia is the most common cardiopulmonary complication during ERCP, with a reported rate of 16.2 to 39.2%. The key to preventing hypoxia is to ensure the sufficient oxygenation and ventilation of patients during these procedures. The commonly used approaches to treat hypoxia with a non-instrumented airway are increasing the oxygen flow and lifting the jaw, applying with both hands, displacing the jaw upwards and anteriorly, which allowed the upper airway to remain open. We hypothesized that the supraglottic oxygen delivery via an endotracheal tube can reduce the incidence of hypoxia in patients under deep sedation during ERCP.",[26,27,28,29],[31,61,62,63],"respiratory depression","Hypoxia","Sedation","RECRUITING","2025-07-14",{"date":67,"type":40},"2025-07-17",{"date":69,"type":40},"2025-06-12",{"date":71,"type":20},"2026-12-31",{"name":46,"class":47},1,{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":21,"phases":81,"briefSummary":82,"conditions":83,"keywords":84,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},"100593925","phase-2-combo-endoscopy-oropharyngeal-airway-in-sedated-endoscopic-retrograde-cholangiopancreatography-for-patients-100593925","NCT07012772","COMBO Endoscopy Oropharyngeal Airway in Sedated Endoscopic Retrograde Cholangiopancreatography for Patients","Inclusion Criteria:\n\n* Age ≥18 years；\n* The ASA classification ranges from I to III.\n* Patients have signed the informed consent form.\n* Patients scheduled to undergo sedated ERCP examination;\n* The estimated duration of the procedure does not exceed 45 minutes.\n\nExclusion Criteria:\n\n1. Patients with coagulation disorders, tendency for oral\u002Fnasal bleeding, mucosal injury\u002Foccupying lesions, or difficult oropharyngeal airway insertion making airway management unfeasible;\n2. Severe cardiac dysfunction (\\\u003C4 METs);\n3. Severe renal insufficiency (requiring preoperative dialysis);\n4. Child-Pugh class C;\n5. Diagnosed chronic obstructive pulmonary disease (COPD) or other acute\u002Fchronic pulmonary diseases requiring long-term\u002Fintermittent oxygen therapy;\n6. Increased intracranial pressure;\n7. Upper respiratory tract infections (oral\u002Fnasal\u002Fpharyngeal);\n8. Fever (core temperature \\>37.5°C);\n9. Confirmed pregnancy or current breastfeeding;\n10. Allergy to sedatives (e.g., propofol) or medical adhesives;\n11. Emergency procedures;\n12. Multiple trauma injuries;\n13. Peripheral oxygen saturation (SpO2) levels below 95% while breathing room air preoperatively;\n14. BMI \\\u003C18.5 or \\>30 kg\u002Fm²;\n15. Current participation in other clinical trials;\n16. Other conditions deemed ineligible by investigators.",{"count":55,"type":20},[57],"Hypoxia represents the prevailing adverse occurrence during the sedation of patients undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) with propofol. A recent innovation in this domain is the COMBO Endoscopy Oropharyngeal Airway-a multifaceted device that encompasses capnography monitoring, bite block , oxygenation support, and oropharyngeal airway management. This device has been purposefully designed to cater to the unique requirements of endoscopic procedures. The principal objective of this study is to assess the efficacy of the COMBO Endoscopy Oropharyngeal Airway in reducing the incidence of hypoxia in patients undergoing ERCP under sedation.",[26,27,28,29],[61,85,62,63,31],"The COMBO Endoscopy Oropharyngeal Airway","2025-06-23",{"date":88,"type":40},"2025-06-24",{"date":69,"type":40},{"date":91,"type":20},"2025-12-31",{"name":46,"class":47},2]