[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cholelithiases\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cholelithiases":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100638697","ultrasound-guided-rectus-sheath-block-versus-local-infiltration-100638697",false,"NCT07582029","Ultrasound-Guided Rectus Sheath Block Versus Local Infiltration","Comparison of the Analgesic Effects of Local Anesthetic Infiltration and Ultrasound-Guided Rectus Sheath Block in Laparoscopic Cholecystectomy Operations: A Prospective Randomized Controlled Study","Inclusion Criteria:\n\n* ASA (American Society of Anesthesiologists) class I-II patients\n* Patients aged between 18 and 65 years\n* Patients undergoing laparoscopic cholecystectomy surgery\n\nExclusion Criteria:\n\n* ASA class III-IV patients\n* Patients undergoing emergency surgery\n* Relatives of patients who do not provide consent\n* Presence of chronic pain\n* Chronic opioid use\n* Presence of local anesthetic allergy\n* Ibuprofen allergy\n* Paracetamol allergy\n* Presence of infection at the block site\n* Coagulopathy\n* Increased intracranial pressure\n* Pre-existing neurological deficit\n* Severe organ failure\n* Mental retardation\n* Anatomical deformity","ALL","18 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","Laparoscopic cholecystectomy is associated with significant postoperative pain originating from trocar sites, pneumoperitoneum, and visceral irritation. Both local anesthetic infiltration and ultrasound-guided rectus sheath block are commonly used regional analgesic techniques to reduce postoperative pain and opioid consumption. This prospective randomized controlled study aims to compare the effects of these two techniques on postoperative pain scores, opioid requirements, and analgesia-related adverse effects following laparoscopic cholecystectomy.",[26,27,28],"Cholelithiases","Cholecystitis","Postoperative Pain",[30,31,32,33],"Cholecystectomy, Laparoscopic","Rectus Sheath Block","Anesthesia, Local","Pain, Postoperative","NOT_YET_RECRUITING","2026-05-06",{"date":37,"type":38},"2026-05-12","ACTUAL",{"date":37,"type":20},{"date":41,"type":20},"2026-12-12",{"name":43,"class":44},"Sisli Hamidiye Etfal Training and Research Hospital","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":45},"100348126","comparison-of-anaesthesia-requirement-for-ventilation-with-endotracheal-tube-versus-proseal-laryngeal-mask-airway-100348126","NCT03812718","Comparison of Anaesthesia Requirement for Ventilation With Endotracheal Tube Versus Proseal Laryngeal Mask Airway","Anaesthesia Requirements for Ventilation With Endotracheal Tube Versus ProSeal Laryngeal Mask Airway During Automated Feedback-Loop Controlled Total Intravenous Anaesthesia in Patients Undergoing Laparoscopic Cholecystectomy: A Randomised Controlled Study","Inclusion Criteria:\n\n1. ASA physical status I\u002FII\n2. Undergoing elective laparoscopic cholecystectomy\n\nExclusion Criteria:\n\n1. Anticipated difficult airway\n2. Body mass index \\> 30-kg\u002Fm2\n3. Uncompensated cardiovascular disease (e.g. uncontrolled hypertension, atrio-ventricular block, sinus bradycardia, congenital heart disease, reduced LV compliance, diastolic dysfunction)\n4. Hepato-renal insufficiency\n5. Uncontrolled endocrinology disease (e.g. diabetes mellitus, hypothyroidism)\n6. Known allergy\u002Fhypersensitivity to the study drug (propofol)\n7. Drug dependence\u002Fsubstance abuse\u002Fpsychiatric illness\n8. Requirement of postoperative ventilation\n9. Refusal to informed consent","65 Years",{"count":55,"type":20},160,[23],"Endotracheal tube (ETT) is the gold standard conduit for providing controlled ventilation during general anaesthesia (GA). however, the supra-glottic airway (SGA) devices in particular the laryngeal mask airway (LMA) and its variants have become a reliable alternative to ETT for carrying out controlled ventilation. Of the several variants of LMA available today, the proseal LMA (PLMA) is preferred for controlled ventilation. The various advantages of LMA includes, a lower incidence of postoperative sore throat and superior haemodynamic profile during surgery. However, one aspect of providing anaesthesia with LMA compared to ETT is the ability of LMA to maintain equivalent depth of anaesthesia with lower anaesthetic requirement, is quiet intriguing and evidence to this regard is very limited.\n\nBy measuring the anaesthesia requirement using a robust computerised delivery system such as the closed loop anaesthesia delivery system (CLADS) we can establish for sure the anaesthesia required for maintaining intraoperative mechanical ventilation with the use of these two (ETT and PLMA) airway management devices.\n\nThis randomised controlled study aims to calculate the anaesthesia requirement as determined by the total amount of propofol consumed for maintaining anaesthesia with ETT versus PLMA",[26,59],"Cholecystolithiasis","RECRUITING","2026-04-22",{"date":63,"type":38},"2026-04-27",{"date":65,"type":38},"2019-03-04",{"date":67,"type":20},"2026-12",{"name":69,"class":44},"Sir Ganga Ram Hospital"]