[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-knee-osteoarthritis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-knee-osteoarthritis":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,39,64],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":4},"100629524","image-guided-genicular-nerve-radiofrequency-ablation-for-chronic-knee-osteoarthritis-100629524",false,"NCT07475793","Image Guided Genicular Nerve Radiofrequency Ablation for Chronic Knee Osteoarthritis","Efficacy of Ultrasound vs Fluoroscopy Guided Genicular Nerve Radiofrequency Ablation for Chronic Knee Osteoarthritis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Both gender patients of age more than 50 years.\n* Radiographic diagnosis of knee OA with KL level 3 and 4.\n* Chronic knee pain for more than 6 months\n* Patients with more than 50% reduction in pain intensity after diagnostic genicular nerve block\n\nExclusion Criteria:\n\n* Lack of consent\n* surgery of knee\n* Patient with BMI more than 40kg\u002Fm2\n* Intra-articular steroid injection or hyaluronic acid in last 3 months\n* Localized infection at procedure site or knee.\n* Patient unable to communicate properly (Severe psychiatric illness, severe dementia and cognitive impairment).\n* Patients have moderate to severe low back pain (NRS ≥5)","ALL","50 Years",{"count":19,"type":20},52,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this prospective randomized control trial is to provide continued pain relief, classically long-lasting 3 to12 months, and enhanced function in patients following: both gender; male and female, age group; \\>50yr, healthy volunteers along with Radiographic diagnosis of knee OA with KL grade 3 and 4 in addition of Chronic knee pain ≥ 6 months and patients with ≥50% decrease in pain strength after diagnostic genicular nerve block. The main question it aims to answer is:\n\nIs ultrasound-guided genicular nerve RFA more efficient in lowering pain intensity at six months contrasted with fluoroscopic guided method in patients with chronic knee osteoarthritis? Researchers will compare Group A (Fluoroscopic) to Group B (Ultrasound) to see comparison in efficiency of ultrasound guided against fluoroscopic guided genicular nerves block for decrease in pain intensity and functional improvement.",[26],"Chronic Knee Osteoarthritis","NOT_YET_RECRUITING","2026-03-24",{"date":30,"type":31},"2026-03-27","ACTUAL",{"date":33,"type":20},"2026-05-01",{"date":35,"type":20},"2027-05-31",{"name":37,"class":38},"Aga Khan University","OTHER",{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":16,"minAge":46,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":21,"phases":49,"briefSummary":50,"conditions":51,"keywords":4,"overallStatus":54,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":59,"leadSponsor":61,"locationsCount":63},"100628983","shock-wave-versus-traditional-physical-therapy-for-adult-chronic-knee-osteoarthritis-100628983","NCT07468734","Shock Wave Versus Traditional Physical Therapy for Adult Chronic Knee Osteoarthritis","Shock Wave Versus Traditional Physical Therapy for Adult Chronic Knee Osteoarthritis: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults ≥ 40 years with clinical and radiographic diagnosis of chronic knee osteoarthritis (KOA) (Kellgren-Lawrence grade II-III).\n* Both sexes.\n* Persistent knee pain ≥ 3 months.\n* Ability to provide consent and participate in interventions.\n\nExclusion Criteria:\n\n* Prior knee surgery within last 6 months.\n* Intra-articular injections in the last 3 months.\n* Systemic inflammatory arthritis or other neurological conditions affecting gait.","40 Years",{"count":48,"type":20},40,[23],"This study aims to compare the effectiveness of extracorporeal shock wave therapy (ESWT) versus structured therapeutic exercise in patients with chronic knee osteoarthritis (KOA), with respect to pain reduction and improvement of knee function.",[52,53,26],"Shock Wave","Traditional Physical Therapy","RECRUITING","2026-03-18",{"date":57,"type":31},"2026-03-19",{"date":55,"type":31},{"date":60,"type":20},"2026-11-30",{"name":62,"class":38},"German International University",1,{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":4,"eligibilityCriteria":70,"healthyVolunteers":11,"sex":16,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":4,"studyType":21,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":4},"100564259","early-phase-1-treating-chronic-pain-of-peripheral-nerve-origin-with-the-novel-noninvasive-hypersound-neuromodulation-system-100564259","NCT06626854","Treating Chronic Pain of Peripheral Nerve Origin With the Novel Noninvasive Hypersound Neuromodulation System","Prospective, Randomized Study to Assess the Safety and Efficacy of the Novel Noninvasive Hypersound Neuromodulation System in the Treatment of Patients With Chronic Pain of Peripheral Nerve Origin, Including Neuropathy, Sciatica, and Joint Pain","Inclusion Criteria:\n\n* Pain greater than mid-range using standardized pain inventory (SPI).\n* No medication for pain both over-the-counter and by prescription for 24 hours prior to treatment.\n* Body mass index (BMI) to be calculated for all participants with limitation for any BMI that is lower than normal. (Target is normal, overweight or obese).\n* Age greater than 18.\n\nExclusion Criteria:\n\n* Existing Peripheral Nerve Stimulator Implant in the lower extremities","18 Years","75 Years",{"count":74,"type":20},5,[76],"EARLY_PHASE1","First, the subject will undergo screening and provide informed consent. Baseline measurements are then taken. The subject remains seated with back support throughout the session. The technician verifies and marks the knee for treatment and wraps an antenna applicator strap around the lower leg near the knee. The device is turned on in test mode to confirm the therapy location, with the subject identifying when they feel a sensation over their pain area. The power threshold for this sensation is recorded. The therapy, which lasts 15 minutes, is delivered at 90% of this threshold to ensure the subject does not feel it. After therapy, post-treatment measurements are taken.",[79,26,80],"Chronic Knee Pain","Post Surgical Neuropathic Pain",[82,83,84,85],"rfPNS","Hypersound","Neuroharmonix","Noninvasive PNS","2026-02-19",{"date":88,"type":31},"2026-02-23",{"date":90,"type":20},"2026-06-10",{"date":92,"type":20},"2026-12-10",{"name":94,"class":95},"Hypersound Medical Inc","INDUSTRY"]