[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-liver-disease-and-cirrhosis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-liver-disease-and-cirrhosis":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100415541","constitution-of-a-biological-collection-to-establish-preclinical-translational-models-for-the-study-of-tumors-and-chronic-liver-diseases-100415541",false,"NCT04690972","\"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases\".","LivMOD","Inclusion Criteria:\n\n1. Patients\n\n   * diagnosed with chronic liver disease (viral or not)\n   * diagnosed with at least one liver nodule for which a biopsy is planned as part of the care\n   * for hepatobiliary surgery planned as part of care\n   * for locoregional treatment for HCC is indicated\n2. Patients able to receive and understand information relating to the study and give their written informed consent\n3. Patients affiliated to the French social security system\n\nExclusion Criteria:\n\n1. Minor patients\n2. Patients under legal protection,\n3. Patients subject to legal protection or unable to express their consent,\n4. Patients in a situation of social fragility,\n5. Pregnant or breastfeeding woman,\n6. No signing of informed consent.","ALL","18 Years",{"count":19,"type":20},800,"ESTIMATED","OBSERVATIONAL","Development of preclinical translational models for chronic liver tumors and diseases study, such as spheroids cultured in autologous medium and murine xenograft models to test the efficacy of new therapeutic strategies.",[24,25,26,27,28,29,30],"Chronic Liver Disease and Cirrhosis","Liver Cancer","Non-Alcoholic Fatty Liver Disease","Non-Alcoholic Steatohepatitis","Viral Hepatitis B","Viral Hepatitis C","Viral Hepatitis D",[32,33,34,35,36],"Liver disease","Ex vivo models","Single cell","Biomarkers","Spheroïds","RECRUITING","2026-02-10",{"date":40,"type":41},"2026-02-12","ACTUAL",{"date":43,"type":41},"2021-01-14",{"date":45,"type":20},"2029-09-02",{"name":47,"class":48},"Institut National de la Santé Et de la Recherche Médicale, France","OTHER_GOV",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":56,"minAge":17,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":49},"100613561","impact-of-liver-transplantation-on-sexual-life-and-function-100613561","NCT07268196","Impact of Liver Transplantation on Sexual Life and Function","Inclusion Criteria:\n\n1. Married male Patients.\n2. Decompensated Chronic Liver Disease awaiting elective liver transplantation.\n3. Post Liver Transplant patients with stable graft function.\n\nExclusion Criteria:\n\n1. Negative consent.\n2. Patients with ongoing medical and surgical issues (biliary complications, graft complication etc.).\n3. Acute on Chronic Liver Failure and Acute Liver Failure patients.","MALE","60 Years",{"count":59,"type":20},100,"Liver Transplantation (LT) is a lifesaving intervention with around 90% of recipients currently surviving the first postoperative year and subsequent life expectancy now exceeding 20 years. After the post-operative recovery period, however, LT recipients become more and more confronted with the challenges of re-engagement with life after transplantation, a need to reach a new stability, reestablish function in everyday life, reconnect with valued roles, regain independence, and resume work Sexual function is a very important parameter in the evaluation of Quality of Life (QoL), as it has been shown that sexual dysfunction in transplant patients is associated with increased depression and decreased QoL. There are several studies in the relevant literature supporting the recovery of sexual function in patients after liver transplantation. It has been found that recovery was observed in erectile dysfunction in male patients 6 months after liver transplantation.",[24],"2025-12-24",{"date":64,"type":41},"2025-12-31",{"date":66,"type":41},"2025-12-07",{"date":68,"type":20},"2026-10-23",{"name":70,"class":71},"Institute of Liver and Biliary Sciences, India","OTHER",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":49},"100549328","hepatomir-cacld-study-100549328","NCT06432582","hepatomiR cACLD Study","Assessment of a hepatomiR Cut-off for Predicting Specific Hepatic Decompensation Events in Advanced Chronic Liver Disease","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Chronic liver disease (more than 6 months)\n* LSM ≥ 10 kPa\n* Outpatient at the Clinical Department of Internal Medicine II, University Hospital St. Pölten\n* Signed patient consent form\n\nExclusion Criteria:\n\n* Age older than 18 years\n* Pregnancy\n* Primary hepatic malignancy (hepatocellular carcinoma, cholangiocarcinoma) with portal invasion and\u002For extrahepatic spread",{"count":80,"type":20},156,"This study looks to gather data on hepatomiR, a CE-certified test already intended for gauging liver-related outcomes, in order to define a cut-off regarding specific decompensation events (ascites, variceal hemorrhage, hepatic encephalopathy) in chronic liver disease (CLD). Based on these data, it is aimed to advance the current understanding of factors driving decompensation, with potential repercussions for future risk management and therapy.",[24,83,84],"Chronic Liver Disease","Portal Hypertension",[86,87,88,89],"hepatomiR","micro-RNA","hepatic decompensation","ACLD","2025-09-08",{"date":92,"type":41},"2025-09-09",{"date":94,"type":41},"2024-05-15",{"date":96,"type":20},"2026-06",{"name":98,"class":71},"Karl Landsteiner University of Health Sciences"]