[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-lower-back-pain-clbp\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-lower-back-pain-clbp":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100575394","brief-pain-reprocessing-therapy-in-veterans-100575394",false,"NCT06771713","Brief Pain Reprocessing Therapy in Veterans","Brief Pain Reprocessing Therapy: An Optimized Integrative Exposure Intervention for Veterans With Chronic Low Back Pain","Inclusion Criteria:\n\n* Low back pain that has lasted greater than 6 months, with pain on at least half of these days\n* Must provide verification of being an Armed Service Veteran.\n* Able to read, write and speak English\n* Internet access and audio-conferencing capability (e.g., Zoom meetings by phone or computer) in the home\n\nExclusion Criteria:\n\n* Self-reported evidence of a separate medical condition (e.g., rheumatoid arthritis), acute injury in the past 12 months (e.g., self-reported spinal fracture), self-reported loss of bowel or bladder control in the past year (which may indicate presence of cauda equina syndrome), or evidence of presence of a metastasizing cancer requiring treatment\n* Pending surgical procedures or interventional therapies (e.g., spinal injections) within the next 12 months\n* Confirmed\u002Fsuspected pregnancy\n* Evidence of other conditions that may preclude participants from understanding or being able to participate in study procedure (e.g., schizoaffective disorder, suspected or diagnosed dementia)\n* Currently receiving cognitive-behavioral therapy or other psychological therapies for pain\n* Open litigation in the past 1 year, as assessed in preliminary study screening.\n* Any other diseases or conditions that would make a patient unsuitable for study participation as determined by the site principal investigators.","ALL","18 Years",{"count":19,"type":20},50,"ESTIMATED","INTERVENTIONAL",[23],"NA","This research is studying whether a Zoom-based behavioral intervention may have an impact as a treatment for Veterans with Chronic Low Back Pain (CLBP).\n\nThe study will examine:\n\n* The acceptability of the Brief Pain Reprocessing Therapy (BPRT) intervention\n* The feasibility of the BPRT intervention\n* The safety of the BPRT intervention",[26],"Chronic Lower Back Pain (CLBP)",[28,29,30],"Veterans","Telehealth based intervention","Brief Pain Reprocessing Therapy","RECRUITING","2026-05-18",{"date":34,"type":35},"2026-05-22","ACTUAL",{"date":37,"type":35},"2025-03-10",{"date":39,"type":20},"2027-06",{"name":41,"class":42},"University of Michigan","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":43},"100595495","virtual-reality-treatment-for-adults-with-chronic-back-pain-vrnt-100595495","NCT07033195","Virtual Reality Treatment for Adults With Chronic Back Pain (VRNT)","Efficacy of a Virtual Reality Neuroscience-based Therapy (VRNT) for Chronic Low Back Pain","Inclusion Criteria:\n\n* Men and women aged 18 to 85.\n* Self-reported diagnosis of chronic low back pain without radicular symptoms.\n* Chronic low back pain duration of 6 months or more, and pain at least half the days in the last 6 months.\n* Lower back pain as primary chronic pain complaint (greater than pain in other bodily regions).\n* Average pain intensity of 4 or more out of 10 for the past week (from BPI-SF).\n* English fluency (8th grade level).\n* Willing to comply with study procedures\u002Frestrictions.\n* Access to Wi-Fi.\n* Implicit de facto internet and computer literacy.\n\nExclusion Criteria:\n\n* Applicants, who are pregnant, planning pregnancy, or breastfeeding\n* Back pain associated with compensation \u002F litigation within 1 year.\n* Leg pain greater than back pain (suggests neuropathic pain; may be less responsive to psychological therapy).\n* Chronic pain other than chronic back pain.\n* Diagnoses of schizophrenia, multiple personality dissociative identity disorder.\n* History of major depressive disorder not controlled with medication or other conditions that produce significant cognitive or emotional disability.\n* History of substance abuse.\n* Inability to undergo MRI (determined at screening; see XVI: Risks to Participants).\n* Any clinically significant unstable medical abnormality or acute or chronic disease of cardiovascular, gastrointestinal, respiratory (e.g., chronic obstructive pulmonary disease), hepatic, or renal systems; including: history of cardiovascular disease or issues (e.g., recent heart attack), stroke; brain surgery, or brain tumor; Diabetes; cancer (last 12 months); diagnosis of a specific inflammatory disorder: rheumatoid arthritis, polymyalgia rheumatica, scleroderma, Lupus; polymyositis; or Cauda Equina syndrome.\n* History of seizure disorder, epilepsy, convulsions, or increased intracranial pressure anytime except pediatric febrile seizures.\n* History of vertigo, dizziness, susceptibility to motion sickness\n* History of head injury within 6 months,\n* Unexplained, unintended weight loss of 'â• 20 lbs in past year. Self-reported history of (digital) eye strain or computer vision syndrome. Unable or unwilling to meet study attendance requirements. MRI contraindications as determined by MRI safety screen (e.g., pregnancy, metal in body, claustrophobia, using the standard screen conducted by the MRI imaging facility).","85 Years",{"count":53,"type":20},200,[23],"Participants with chronic back pain will complete an online Qualtrics eligibility survey. After signing a consent form, eligible participants enter a two-week baseline period (\"Baseline Period\"), during which they complete two assessments of the Primary and Secondary Outcome Measures and Potential Mediators. After the baseline period, participants are randomized into a Virtual Reality group: VR Distraction-based Therapy or VR Skills-based Therapy, with a 1:1 allocation ratio of participants to each treatment. Both groups receive education on pain neuroscience and complete training on the use of the VR hardware and software. Next, both groups complete an intervention for 8 weeks (\"Treatment Period\"), after which they return the VR equipment. Several surveys are administered online during the Treatment Period. After the Treatment Period, both groups complete three post-treatment surveys at weeks 8, 20, and 32.",[57,58,26],"Chronic Pain","Chronic Back Pain",[60,61,62,63],"chronic pain relief","back pain","chronic back pain","chronic lower back pain","2026-04-01",{"date":66,"type":35},"2026-04-02",{"date":68,"type":35},"2025-06-01",{"date":70,"type":20},"2027-05-20",{"name":72,"class":73},"CognifiSense Inc.","INDUSTRY"]