[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-neck-pain\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-neck-pain":29},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,32,0,25,[9,53,75,98,129,161,184,211,236,259,285,313,340,361,385,415,443,472,497,522,550,573,592,613,631],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":16,"eligibilityCriteria":17,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":33,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100054226","effects-of-different-myofascial-release-techniques-on-function-in-chronic-non-specific-neck-pain-100054226",false,"NCT07694882","Effects of Different Myofascial Release Techniques on Function in Chronic Non-Specific Neck Pain","Investigation of the Effects of Different Myofascial Release Techniques on Functional Outcomes in Individuals With Chronic Non-Specific Neck Pain","MFR \u002F CNNP","Inclusion Criteria:\n\n* Neck pain persisting for at least 3 months and diagnosed as chronic non-specific neck pain by a specialist physician\n* Aged between 18 and 45 years\n* Perceived pain affecting daily living activities (VAS at least 3)\n* Presence of myofascial trigger points in the upper-quarter muscles\n\nExclusion Criteria:\n\n* Specific serious cervical spine pathology (radiculopathy, myelopathy, severe nerve root compression, spondylosis, and similar)\n* History of rheumatologic, neurologic, or systemic disease (for example, acute inflammation, multiple sclerosis, Parkinson's disease, rheumatoid arthritis, fibromyalgia, or cancer)\n* History of trauma, fracture, or surgery involving the neck, shoulder, or upper extremity\n* Pregnancy or breastfeeding\n* Any diagnosed psychiatric disorder (for example, major depression or anxiety disorder) or regular use of psychopharmacological medication\n* Use of systemic analgesics, NSAIDs, or muscle relaxants within the last 7 days for pain control\n* Any physiotherapy, manual therapy, or injection treatment to the neck region within the last 3 months","ALL","18 Years","45 Years",{"count":22,"type":23},84,"ESTIMATED","INTERVENTIONAL",[26],"NA","This single-center, three-arm randomized controlled trial compares the effects of different myofascial release techniques, combined with a structured exercise program, on functional outcomes in individuals with chronic non-specific neck pain (CNNP).\n\nEligible participants (aged 18 to 45 years, neck pain for at least 3 months, pain intensity VAS at least 3, and myofascial trigger points in the upper-quarter muscles) are allocated by simple randomization into three groups:\n\n* Conventional Therapy Group: hot pack, conventional TENS, and a structured exercise program.\n* Manual Myofascial Release Group: conventional therapy plus therapist-applied manual myofascial release.\n* Self-Myofascial Release Group: conventional therapy plus supervised self-applied myofascial release using a duo-ball, balls, and a massage stick\u002Fcane.\n\nAll interventions are delivered 3 days per week for 6 weeks. The primary outcome is pain intensity. Secondary outcomes include pressure pain threshold and tolerance, cervical range of motion, muscle stiffness, craniovertebral angle, cervical proprioception, muscle strength and endurance, disability, neck awareness, multidimensional biopsychosocial status, sleep quality, quality of life, and kinesiophobia. The aim is to determine whether manual or self-applied myofascial release, added to exercise, produces greater functional improvement in people with chronic non-specific neck pain.",[29,30,31,32],"Chronic Neck Pain","Non-specific Neck Pain","Myofascial Trigger Points","Myofascial Pain Syndrome - Neck",[34,35,36,37,38,39],"chronic non-specific neck pain","myofascial release","manual therapy","trigger points","therapeutic exercise","physiotherapy","NOT_YET_RECRUITING","2026-07-10",{"date":43,"type":44},"2026-07-13","ACTUAL",{"date":46,"type":23},"2026-07-15",{"date":48,"type":23},"2026-12-31",{"name":50,"class":51},"Eastern Mediterranean University","OTHER",1,{"id":54,"slug":55,"hasResults":12,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":59,"enrollmentInfo":60,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":63,"conditions":64,"keywords":65,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":70,"completionDateStruct":71,"leadSponsor":73,"locationsCount":52},"100053931","the-correlation-between-central-conduction-time-and-central-pain-syndrome-in-chronic-neck-pain-100053931","NCT07698691","The Correlation Between Central Conduction Time and Central Pain Syndrome in Chronic Neck Pain","Inclusion Criteria:\n\n* Participants aged 18-35 years.\n* Normal Body Mass Index (BMI) less than 25 kg\u002Fm2.\n* Both genders were included.\n* having chronic neck pain lasting for more than three months.\n\nExclusion Criteria:\n\n* signs of serious pathology (e.g., malignancy, inflammatory disorders, infection).\n* history of cervical spine surgery.\n* history of trauma or fractures in the cervical spine.\n* presence of vascular syndromes such as vertebrobasilar insufficiency.","35 Years",{"count":61,"type":23},120,"OBSERVATIONAL","To investigate the neurophysiological relationship between Central Conduction Time measured via Somatosensory evoked potentials and pain intensity in individuals suffering from chronic neck pain",[29],[66,67,29],"Central Conduction Time","Central Pain Syndrome","2026-07-07",{"date":43,"type":44},{"date":41,"type":23},{"date":72,"type":23},"2026-09-01",{"name":74,"class":51},"Cairo University",{"id":76,"slug":77,"hasResults":12,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":24,"phases":85,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":52},"100630462","acute-effects-of-motor-imagery-and-motor-control-exercises-in-individuals-with-chronic-neck-pain-100630462","NCT07487987","Acute Effects of Motor Imagery and Motor Control Exercises in Individuals With Chronic Neck Pain","Comparison of the Acute Effects of Motor Imagery and Motor Control Exercises in Individuals With Chronic Neck Pain","Inclusion Criteria:\n\n* Neck pain lasting at least 12 weeks,\n* VAS score of at least 3 cm,\n* Standardized Mini Mental Test score of at least 24.\n\nExclusion Criteria:\n\n* History of cervical surgery,\n* neurological deficit,\n* malignancy,\n* rheumatic diseases,\n* having received physical therapy for the neck region within the last 3 months","65 Years",{"count":84,"type":23},40,[26],"The aim of this study is to compare the effects of single-session motor imagery and motor control exercises on pain, pressure pain threshold, cervical proprioception, and motor imagery in individuals with chronic neck pain.",[29],"RECRUITING","2026-07-01",{"date":91,"type":44},"2026-07-02",{"date":93,"type":44},"2026-03-10",{"date":95,"type":23},"2026-09-14",{"name":97,"class":51},"KTO Karatay University",{"id":99,"slug":100,"hasResults":12,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":4,"eligibilityCriteria":104,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":105,"enrollmentInfo":106,"targetDuration":4,"studyType":24,"phases":108,"briefSummary":109,"conditions":110,"keywords":111,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":52},"100641610","longitudinal-stripping-massage-vs-percussion-device-for-neck-pain-ultrasound-study-100641610","NCT07630142","Longitudinal Stripping Massage vs. Percussion Device for Neck Pain: Ultrasound Study.","The Effect of Percussion Therapy on Neck Functional Disability, Pain and Upper Trapezius Muscle Properties Assessed by Elastography and Doppler Ultrasound in Patients With Neck Pain.","Inclusion Criteria:\n\n* Age: 18-60 years\n* Neck pain persisting for at least 3 months\n* Visual Analog Scale (VAS) score between 3 and 7\n* Neck Disability Index (NDI) between 30% and 48%\n\nExclusion Criteria:\n\n* Pregnancy and postpartum period\n* History of cervical spine or shoulder surgery\n* Diagnosed fibromyalgia, radiculopathy, or myelopathy\n* Myofascial therapy within the last 3 months\n* Use of analgesic medication within 48 hours before assessment\n* Venous diseases","60 Years",{"count":107,"type":23},35,[26],"This study evaluates whether a single session of percussion therapy can reduce muscle tension and increase blood flow in the transverse cervical artery in individuals with neck pain. The investigators will evaluate muscle stiffness using ultrasound elastography, and assess blood flow in the transverse cervical artery via Doppler imaging before and after treatment. The primary objective is to determine how this therapy affects neck muscle relaxation and vascular responses, specifically within the upper trapezius region.",[29],[112,113,114,115,116,117,118,119],"neck pain","longitudinal stripping massage","percussion massage","trapezius","elastography","shear wave","Doppler ultrasound","cervical pain","2026-06-14",{"date":122,"type":44},"2026-06-17",{"date":124,"type":23},"2026-06-01",{"date":126,"type":23},"2029-06-01",{"name":128,"class":51},"Poznan University of Physical Education",{"id":130,"slug":131,"hasResults":12,"nctId":132,"briefTitle":133,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":135,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":137,"conditions":138,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":4},"100643683","prospective-case-series-evaluating-6-month-and-12-month-outcomes-after-cryoneurolysis-for-chronic-pain-100643683","NCT07639060","Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain","Inclusion Criteria:\n\n* Diagnosis of chronic pain (generally pain duration of at least 3-6 months) localized to an anatomical region appropriate for cryoneurolysis as determined by the treating physician.\n* Planned cryoneurolysis procedure as part of standard clinical care.\n* Ability to provide written informed consent.\n* Ability and willingness to complete baseline and follow-up questionnaires.\n\nExclusion Criteria:\n\n* Cryoneurolysis performed as part of a separate investigational trial in which data sharing is not permitted.\n* Active infection or other clinical contraindication to the procedure as determined by the treating clinician.\n* Life expectancy of less than 12 months in the judgment of the treating clinician.\n* Any condition that, in the investigator's opinion, would interfere with study participation or completion of follow-up, such as severe psychiatric instability or active substance use that precludes reliable follow-up",{"count":136,"type":23},80,"To prospectively describe patient-centered and health utilization outcomes through 12 months after cryoneurolysis performed as routine clinical care for chronic pain at Yale.",[139,140,141,142,143,144,145,146,147,148,149,150,151,29],"Chronic Pain","PERIPHERAL NEUROPATHY","Occipital Neuralgia","Chronic Hip Pain","Hip Osteoarthritis","Knee Osteoarthritis","Spasticity","Chronic Low Back Pain","Lumbar Spondylosis","Cervical Spondylosis","Shoulder Arthritis","Causalgia","Chronic Pain Syndrome","2026-06-05",{"date":154,"type":44},"2026-06-10",{"date":156,"type":23},"2026-06",{"date":158,"type":23},"2028-07",{"name":160,"class":51},"Yale University",{"id":162,"slug":163,"hasResults":12,"nctId":164,"briefTitle":165,"officialTitle":166,"acronym":167,"eligibilityCriteria":168,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":169,"targetDuration":4,"studyType":24,"phases":171,"briefSummary":172,"conditions":173,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":176,"lastUpdatePostDateStruct":177,"startDateStruct":179,"completionDateStruct":181,"leadSponsor":182,"locationsCount":52},"100637894","cervical-medial-branch-block-versus-ipsilateral-cervical-erector-spinae-plane-block-100637894","NCT07595406","Cervical Medial Branch Block Versus Ipsilateral Cervical Erector Spinae Plane Block","Ultrasound-Guided Cervical Medial Branch Block Versus Ipsilateral Cervical Erector Spinae Plane Block in Cervical Facetogenic Pain: A Prospective Randomized Controlled Study","CERVESP","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* Chronic neck pain lasting at least 3 months\n* Clinical findings suggestive of cervical facetogenic pain\n* Numeric Rating Scale pain score ≥4\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Cervical radiculopathy or myelopathy\n* Major neurological deficit\n* Infection at the injection site\n* Coagulopathy or anticoagulant therapy contraindicating intervention\n* Allergy to local anesthetics\n* Pregnancy\n* Previous cervical interventional pain procedure within the last 3 months\n* Severe psychiatric disease",{"count":170,"type":23},130,[26],"This prospective randomized controlled study aims to compare the analgesic effectiveness of ultrasound-guided cervical medial branch block and ipsilateral cervical erector spinae plane block in patients with cervical facetogenic pain.\n\nPatients with chronic cervical facet-mediated pain will be randomized into two intervention groups. Pain intensity, functional status, meaningful pain response rates, analgesic consumption, and patient satisfaction will be evaluated during follow-up.\n\nThe primary objective is to determine whether cervical erector spinae plane block provides comparable short-term pain relief to cervical medial branch block.",[174,29,175],"Cervical Facetogenic Pain","Cervical Facet Joint Syndrome","2026-05-12",{"date":178,"type":44},"2026-05-19",{"date":180,"type":23},"2026-05-31",{"date":48,"type":23},{"name":183,"class":51},"Ankara City Hospital Bilkent",{"id":185,"slug":186,"hasResults":12,"nctId":187,"briefTitle":188,"officialTitle":189,"acronym":4,"eligibilityCriteria":190,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":191,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":193,"conditions":194,"keywords":195,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":206,"completionDateStruct":208,"leadSponsor":209,"locationsCount":52},"100633351","kinesiophobia-pain-and-disability-in-chronic-neck-pain-100633351","NCT07525557","Kinesiophobia, Pain and Disability in Chronic Neck Pain","Kinesiophobia As A Mediator Of The Association Between Pain Intensity And Disability In Chronic Neck Pain","Inclusion Criteria:\n\n* Individuals aged 18 years or older\n* Presence of chronic neck pain lasting at least 3 months\n* Ability to understand and complete questionnaires\n* Voluntary participation\n\nExclusion Criteria:\n\n* Acute neck pain (\\\u003C 3 months)\n* History of cervical spine surgery\n* Neurological disease or cervical radiculopathy\n* Inflammatory, neoplastic, or traumatic conditions affecting the neck\n* Cognitive impairment preventing questionnaire completion",{"count":192,"type":23},250,"This study aims to investigate the mediating role of kinesiophobia in the relationship between pain intensity and disability in individuals with chronic neck pain. Chronic neck pain is a multidimensional clinical condition influenced not only by biological factors but also by psychological components such as fear of movement. Understanding the mechanisms underlying disability may contribute to more targeted rehabilitation strategies. Participants with chronic neck pain lasting at least three months will be assessed using validated self-report questionnaires measuring pain intensity, kinesiophobia, disability, and physical activity levels.",[29],[196,139,197,198,199,200,201,202],"Kinesiophobia","Musculoskeletal Pain","Disability Evaluation","Pain Measurement","Fear Avoidance","Neck Disability Index","Tampa Scale of Kinesiophobia","2026-05-07",{"date":205,"type":44},"2026-05-11",{"date":207,"type":44},"2026-04-10",{"date":89,"type":23},{"name":210,"class":51},"Ondokuz Mayıs University",{"id":212,"slug":213,"hasResults":12,"nctId":214,"briefTitle":215,"officialTitle":216,"acronym":4,"eligibilityCriteria":217,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":82,"enrollmentInfo":218,"targetDuration":4,"studyType":24,"phases":220,"briefSummary":221,"conditions":222,"keywords":223,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":228,"lastUpdatePostDateStruct":229,"startDateStruct":231,"completionDateStruct":233,"leadSponsor":234,"locationsCount":4},"100639288","mindfulness-plus-supervised-rehabilitation-vs-supervised-rehabilitation-alone-for-chronic-neck-pain-in-office-workers-100639288","NCT07576556","Mindfulness Plus Supervised Rehabilitation vs Supervised Rehabilitation Alone for Chronic Neck Pain in Office Workers","Effect of Mindfulness Combined With Supervised Rehabilitation Versus Supervised Rehabilitation Alone in Office Workers With Chronic Neck Pain: Protocol for a Randomized Controlled Trial","Inclusion Criteria:\n\n* Office workers aged 18 years or older\n* diagnosed with chronic neck pain for more the three months\n\nExclusion Criteria:\n\n* history of neck surgery\n* history of cervical trauma\n* history of neurological disorders affecting the neck or upper extremities\n* currently receiving other treatments for neck pain, such as injections or surgical interventions\n* Participants with significant psychiatric disorders that could interfere with study participation or adherence to the intervention",{"count":219,"type":23},48,[26],"The goal of this clinical trial is to learn if adding mindfulness to supervised rehabilitation exercises improves outcomes in office workers with chronic neck pain. It will also evaluate the impact of this combined approach on psychosocial factors and quality of life. The main questions it aims to answer are:\n\nDoes mindfulness combined with supervised exercises reduce neck pain intensity more than supervised exercises alone? Does the combined intervention improve neck-related disability, psychosocial outcomes, and quality of life?\n\nResearchers will compare a mindfulness-based intervention plus supervised rehabilitation exercises to supervised rehabilitation exercises alone to determine whether the combined approach provides additional benefit.\n\nParticipants will:\n\nBe randomly assigned to receive either mindfulness plus supervised exercises or supervised exercises alone for 8 weeks Attend weekly 60-minute mindfulness sessions (experimental group only) and twice-weekly supervised exercise sessions Undergo assessments at the beginning and at the end of the intervention period",[29],[224,225,112,226,227],"office workers","supervised exercise","stress","mindfulness","2026-05-02",{"date":230,"type":44},"2026-05-08",{"date":232,"type":23},"2026-05-01",{"date":48,"type":23},{"name":235,"class":51},"University of Monastir",{"id":237,"slug":238,"hasResults":12,"nctId":239,"briefTitle":240,"officialTitle":241,"acronym":4,"eligibilityCriteria":242,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":59,"enrollmentInfo":243,"targetDuration":4,"studyType":24,"phases":245,"briefSummary":246,"conditions":247,"keywords":248,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":252,"lastUpdatePostDateStruct":253,"startDateStruct":255,"completionDateStruct":256,"leadSponsor":258,"locationsCount":52},"100633811","respiratory-exercises-versus-deep-neck-flexor-training-in-chronic-mechanical-neck-pain-100633811","NCT07531537","Respiratory Exercises Versus Deep Neck Flexor Training in Chronic Mechanical Neck Pain","Effect of Respiratory Muscle Exercises Versus Deep Neck Flexor Training on Pain, Function and Neck Muscle Endurance in Patients With Chronic Mechanical Neck Pain","Inclusion Criteria:\n\n1. Patients have mechanical neck pain lasting longer than three months.\n2. The ages of patients range from 18 to 35 years.\n3. Patients are lifetime non-smoker and non-alcoholic.\n\nExclusion Criteria:\n\n1. History of trauma or cervical spine fractures.\n2. Previous spinal surgery.\n3. Any inflammatory pathology.\n4. Any cervical disc pathology and neurological signs.\n5. Malignancy.\n6. Cervical radiculopathy.\n7. Rheumatoid arthritis.\n8. Pregnant female.\n9. Currently using muscle relaxation medication.\n10. History of respiratory and cardiovascular illness",{"count":244,"type":23},66,[26],"This study will be conducted to compare the effect of adding respiratory exercises versus deep neck flexor training to conventional program on pain, cervical ROM, cervical muscle endurance, function, and chest expansion in patients with chronic mechanical neck pain. Sixty-six (66) of both genders ranging in age from 18 to 35 years old, with a history of mechanical neck pain longer than 3 months (chronic neck pain) will be invited to participate in this study. Participants will be randomly assigned into one of the three experimental groups as follow:\n\nGroup A will receive respiratory exercises in form of diaphragmatic breathing \\& respiratory muscle stretch gymnastics plus conventional program.\n\nGroup B will receive deep neck flexor training in the form of low-load craniocervical flexion using feedback from an air-filled pressure sensor placed behind the neck plus conventional program.\n\nGroup C (control group) will receive conventional program in form of TENS, infrared, isometric neck strengthening exercises and stretching exercises.",[29],[249,250,251],"chronic neck pain","deep neck flexor training","respiratory exercises","2026-04-20",{"date":254,"type":44},"2026-04-22",{"date":93,"type":44},{"date":257,"type":23},"2026-12",{"name":74,"class":51},{"id":260,"slug":261,"hasResults":12,"nctId":262,"briefTitle":263,"officialTitle":264,"acronym":4,"eligibilityCriteria":265,"healthyVolunteers":266,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":267,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":269,"conditions":270,"keywords":273,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":276,"lastUpdatePostDateStruct":277,"startDateStruct":279,"completionDateStruct":281,"leadSponsor":283,"locationsCount":52},"100628987","masseter-muscle-thickness-in-individuals-with-chronic-neck-pain-100628987","NCT07468786","Masseter Muscle Thickness in Individuals With Chronic Neck Pain","Comparison of Masseter Muscle Thickness Measured by Ultrasonography in Individuals With Chronic Neck Pain Compared to Healthy Individuals","Inclusion Criteria:\n\n* Be between the ages of 18 and 45\n* Have neck pain that has persisted for at least 3 months\n* Agree to participate in the study voluntarily and provide written informed consent\n\nExclusion Criteria:\n\n* History of cervical spine surgery or severe trauma\n* Diagnosis of cervical radiculopathy, myelopathy, or neurological disease\n* Rheumatic, inflammatory, or systemic musculoskeletal diseases\n* Diagnosed temporomandibular joint disorder (TMD)\n* Diagnosis of bruxism or a pronounced habit of teeth clenching\u002Fgrinding\n* History of manual therapy, injection, or surgical intervention in the face, jaw, or neck region within the last 6 months\n* Currently undergoing orthodontic treatment or history of orthodontic treatment within the last 6 months\n* Cognitive impairment or conditions that prevent understanding and responding to questionnaires",true,{"count":268,"type":23},90,"The primary objective of our study is to compare the thickness of the masseter muscle, measured by ultrasound, in individuals with chronic neck pain to that of healthy individuals. The secondary objective of the study is to examine the relationships between masseter muscle thickness and pain intensity, neck disability level, pain catastrophizing level, and clinical diagnostic criteria in individuals with chronic neck pain.",[271,272,29],"Masseter Muscle","Ultrasonographic",[249,274,275],"Ultrasonographic measurement","Masseter muscle","2026-03-09",{"date":278,"type":44},"2026-03-13",{"date":280,"type":23},"2026-03-20",{"date":282,"type":23},"2026-05-20",{"name":284,"class":51},"Hasan Kalyoncu University",{"id":286,"slug":287,"hasResults":12,"nctId":288,"briefTitle":289,"officialTitle":289,"acronym":4,"eligibilityCriteria":290,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":291,"enrollmentInfo":292,"targetDuration":4,"studyType":24,"phases":294,"briefSummary":295,"conditions":296,"keywords":299,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":305,"lastUpdatePostDateStruct":306,"startDateStruct":307,"completionDateStruct":309,"leadSponsor":311,"locationsCount":52},"100618532","symmetrical-scapula-pelvis-proprioceptive-neuromuscular-facilitation-and-superficial-back-line-in-chronic-neck-pain-with-hamstring-tightness-100618532","NCT07332845","Symmetrical Scapula-pelvis Proprioceptive Neuromuscular Facilitation and Superficial Back Line in Chronic Neck Pain With Hamstring Tightness","Inclusion Criteria:\n\n* Individual with both male and female gender\n* Individuals with chronic neck pain (pain for \\> 3 month) with hamstring tightness\n\nExclusion Criteria:\n\n* Any history related to spinal surgery\n* Previous administration of epidural injections\n* Neck pain due to specific pathology\n* Patients with radiculopathy or myelopathy\n* Traumatic spinal cord injury\n* Neck pain associated with progressive neurological deficit or loss of strength","40 Years",{"count":293,"type":23},156,[26],"A research study will be conducted at Physiotherapy department of the Sindh Institute of Physical Medicine and Rehabilitation, Karachi, Pakistan. Overall 156 patients with 18-40 years old individuals with neck pain will be eligible and they will be included through non-probability, purposive sampling technique. The written informed consent will be taken from all the patients. They will be divided through Simple random sampling (computer generated software) method into two groups, 78 in each group. Group A (experimental group) will receive PNF Symmetrical Scapula-Pelvis Patterns (PNF-SSPP), group B (control group) will receive sub occipital muscle inhibition technique (SMI) and static stretching (SS) of hamstring muscle. All participants will be assessed using assessment form. Outcome measures will be Pain, disability, disability, neck range of motions, hamstring tightness, head posture, and levator scapulae index. An independent assessor blinded to the treatment will assess all the patients for treatment outcome assessment at baseline, after first session and post treatment. Treatment sessions will be given thrice a week for 6 weeks.",[29,297,298],"Hamstring Muscle Tightness","Neck Pain",[300,301,302,303,304],"neck ache","Exercise","Muscle Stretching","Muscle Inhibition","PNF","2026-03-08",{"date":93,"type":44},{"date":308,"type":44},"2026-01-16",{"date":310,"type":23},"2026-11-26",{"name":312,"class":51},"University of Karachi",{"id":314,"slug":315,"hasResults":12,"nctId":316,"briefTitle":317,"officialTitle":318,"acronym":4,"eligibilityCriteria":319,"healthyVolunteers":12,"sex":18,"minAge":320,"maxAge":82,"enrollmentInfo":321,"targetDuration":4,"studyType":24,"phases":323,"briefSummary":324,"conditions":325,"keywords":326,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":331,"lastUpdatePostDateStruct":332,"startDateStruct":334,"completionDateStruct":336,"leadSponsor":338,"locationsCount":52},"100626191","effects-of-different-exercise-protocols-on-physical-and-cognitive-changes-in-people-with-chronic-neck-pain-100626191","NCT07432425","Effects of Different Exercise Protocols on Physical and Cognitive Changes in People With Chronic Neck Pain","Effects of Different Exercise Protocols on Physical Status, Cognitive Functions, Brain Structure, and Blood Biomarkers in People With Chronic Neck Pain","Inclusion Criteria:\n\n* Participants aged 20-65\n* Having neck pain at least 3 months and rated as 3 or more according to the Numeric Rating Scale\n* Having a score of 10 or more according to the Neck Disability Index\n* Having a score of 24 or above according to the Mini Mental State Examination\n* Right hand dominancy according to Edinburgh Handedness Inventory\n* Having at least a primary school graduate\n\nExclusion Criteria:\n\n* Having neuropsychiatric, neurologic, metabolic, cardiovascular, and inflammatory disease(s)\n* Participating in a rehabilitation program for neck pain in the last 6 months\n* Having an exercise or sports history of 6 months or more\n* Presence of brain parenchymal lesion on MRI\n* Presence of materials in the body such as jewelry, metal, hearing aid, pacemaker, lead that cannot be removed and are not suitable for MRI\n* History of neck or shoulder surgery\n* Being pregnant or having given birth within the last year","20 Years",{"count":322,"type":23},21,[26],"This study aims to investigate the effects of different exercise approaches on physical status, cognitive functions, brain structures, and blood biomarkers in individuals with chronic neck pain.",[298,29],[298,301,327,328,329,330],"Cognition","Neuropsychological test","Neuroimaging","Enzyme-linked immunosorbent assay","2026-02-19",{"date":333,"type":44},"2026-02-25",{"date":335,"type":44},"2025-05-01",{"date":337,"type":23},"2026-03-30",{"name":339,"class":51},"Hacettepe University",{"id":341,"slug":342,"hasResults":12,"nctId":343,"briefTitle":344,"officialTitle":345,"acronym":4,"eligibilityCriteria":346,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":82,"enrollmentInfo":347,"targetDuration":4,"studyType":24,"phases":349,"briefSummary":350,"conditions":351,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":352,"lastUpdatePostDateStruct":353,"startDateStruct":355,"completionDateStruct":357,"leadSponsor":359,"locationsCount":52},"100625130","kinematic-training-in-patients-with-neck-pain-based-on-machine-learning-classification-approach-100625130","NCT07418632","Kinematic Training in Patients With Neck Pain Based on Machine Learning Classification Approach","What is the Ability of Datamining Approaches to Cluster Patients With Idiopathic Neck Pain and Can Machine Learning Algorithms Provide More Efficient Rehabilitation and Less Recurrence Based on Kinaesthetic Training Protocols","Inclusion Criteria:\n\n* presence of neck pain\n* pain level minimum 3 of 10 on VAS\n* did not receive conventional physiotherapy in last 6 months\n\nExclusion Criteria:\n\n* any upper extremity pain within last 2 years\n* any neurological or vestibular dissorders\n* type 2 diabetes\n* diagnosed psychiatric dissorders\n* medication or alcohol consumptin in last 30 hours",{"count":348,"type":23},38,[26],"The goal of this clinical trial is to study if kinematic training based on novel kinematic assessment clasification approach can decrease chronic neck pain and prevent its reoccurance better than conventional kinematic training in adults. The main question\\[s\\] it aims to answer \\[is\u002Fare\\]:\n\nDoes clustering patients with neck pain based on head and neck movement characteristics lead to more efficient kinematic rehabilitation training and improved clinical outcomes\n\nResearchers will compare effects of cluster specific kinematic training to see if it effects pain levels and its reoccurance.\n\nParticipants will \\[describe the main tasks participants will be asked to do, interventions they'll be given and use bullets if it is more than 2 items\\].",[29],"2026-02-13",{"date":354,"type":44},"2026-02-18",{"date":356,"type":23},"2026-03-18",{"date":358,"type":23},"2026-09-20",{"name":360,"class":51},"University of Ljubljana",{"id":362,"slug":363,"hasResults":12,"nctId":364,"briefTitle":365,"officialTitle":365,"acronym":366,"eligibilityCriteria":367,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":368,"enrollmentInfo":369,"targetDuration":4,"studyType":24,"phases":371,"briefSummary":372,"conditions":373,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":377,"lastUpdatePostDateStruct":378,"startDateStruct":380,"completionDateStruct":382,"leadSponsor":383,"locationsCount":4},"100623313","the-effectiveness-of-dynamic-neuromuscular-stabilization-dns-exercises-compared-to-localized-exercises-and-standard-care-on-pain-intensity-neck-dysfunction-and-upper-cervical-range-of-motion-in-patients-with-chronic-neck-pain-a-pilot-randomized-controlled-trial-rct-100623313","NCT07395011","The Effectiveness of Dynamic Neuromuscular Stabilization (DNS) Exercises Compared to Localized Exercises and Standard Care on Pain Intensity, Neck Dysfunction, and Upper Cervical Range of Motion in Patients With Chronic Neck Pain: A Pilot Randomized Controlled Trial (RCT)","DYNEX","Inclusion Criteria:\n\n* between 18 and 50 years of age. This ensures a homogeneous population that in-cludes both young adults and middle-aged individuals.\n* have suffered from neck pain continuously for at least 12 weeks, as described by the International Association for the Study of Pain (IASP)\n* have current neck pain greater than 40 on the Numeric Rating Scale (NRS) (on a scale of 0 to 100).\n* have an NDI score of over 10 points.\n\nExclusion Criteria: -\n\n* Cancer\n* Patients with existing or previous fractures in the cervical spine\n* Patients who have undergone surgery on the cervical spine\n* Patients who, in addition to neck pain, also have or have had dizziness or balance disorders\n* People with osteoporosis\n* Fibromyalgia\n* People with diagnosed rheumatoid arthritis\n* People with red flags identified during a thorough physical examination\n* Patients with neurological deficits identified during a thorough physical examination\n* Participants who have undergone physiotherapy within the last 3 months.","50 Years",{"count":370,"type":23},45,[26],"Many people experience long-lasting neck pain, which can affect daily life, work, and overall well-being. This study aims to find out which type of exercise program is most effective in reducing neck pain, improving neck movement, and making daily activities easier.\n\nWhat Is Being Studied?:\n\nThe study compares three different types of treatment:\n\nDNS Exercises (Dynamic Neuromuscular Stabilization):\n\nWhole-body exercises focusing on posture, breathing, and core stability.\n\nLocalized Neck Exercises:\n\nTargeted exercises for the neck and shoulder muscles.\n\nStandard Care:\n\nUsual physiotherapy treatment commonly provided in clinical practice.\n\nStudy Procedures:\n\nParticipants are randomly assigned to one of the three groups. Each participant receives individual exercise instruction from a physiotherapist.\n\nParticipants are also given simple home exercises to perform on their own. The study lasts for about 12 weeks.\n\nWhat Will Be Measured?:\n\nAt the beginning, during, and at the end of the study, the following will be assessed:\n\nNeck pain intensity (pain scale) Neck range of motion How much the pain affects daily life and activities\n\nPossible Benefits:\n\nParticipants may experience:\n\nLess neck pain Improved neck mobility Better overall body awareness Even if not every participant notices improvement, taking part will help researchers improve future treatment options for chronic neck pain.\n\nRisks:\n\nNo major risks are expected. All exercises are supervised by qualified physiotherapists and adjusted to each participant's abilities.\n\nParticipation can be stopped at any time if discomfort or pain occurs.\n\nVoluntary Participation and Data Privacy:\n\nParticipation is completely voluntary. All personal data will be kept confidential and analyzed anonymously for research purposes only.\n\nParticipants may withdraw from the study at any time without any disadvantages.",[298,374,29,375,376],"Neck Pain Musculoskeletal","Neck Disease","Neck Disability","2026-01-31",{"date":379,"type":44},"2026-02-09",{"date":381,"type":23},"2026-02-02",{"date":48,"type":23},{"name":384,"class":51},"Hochschule Osnabruck",{"id":386,"slug":387,"hasResults":12,"nctId":388,"briefTitle":389,"officialTitle":390,"acronym":391,"eligibilityCriteria":392,"healthyVolunteers":12,"sex":18,"minAge":320,"maxAge":20,"enrollmentInfo":393,"targetDuration":4,"studyType":24,"phases":395,"briefSummary":396,"conditions":397,"keywords":398,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":406,"lastUpdatePostDateStruct":407,"startDateStruct":409,"completionDateStruct":411,"leadSponsor":413,"locationsCount":52},"100586681","progressive-muscle-relaxation-vs-muscle-energy-technique-on-nonspecific-neck-pain-in-prolonged-computer-users-100586681","NCT06918535","Progressive Muscle Relaxation Vs Muscle Energy Technique on Nonspecific Neck Pain in Prolonged Computer Users.","Progressive Muscle Relaxation Vs Muscle Energy Technique on Nonspecific Neck Pain in Prolonged Computer Users. A Randomized Controlled Trial","RCT","Inclusion Criteria:\n\n* Persons using computer more than 6 hours throughout the day, intermittently both genders.\n* Age between 20-45.\n* Hypertonicity of trapezius muscle and SCM muscle. Specifically, those workers have neck pain and stiffness (including trouble tilting or turning head). Patients who reported small tightening and spasm at the posterior aspect of their neck are included, also associated with more diffuse neck pain patterns that included the following: headache, (upper back, neck and shoulder pain) numbness\u002F tingling in the hand\u002Farm.\n* Pain intensity of 2 on the NRS and presence of at least one latent trigger point in a taut band in the neck region.\n\nExclusion Criteria:\n\n* Recent trauma to the cervical region\n* Exclusion criteria based on with any serious pathology such as specific neck pain due to disc prolapsed, tumor of cervical spine, whiplash injury, cervical fractures, Cervicogenic headache, and any neurological signs consistent with nerve root compression",{"count":394,"type":23},60,[26],"The objective of this randomized controlled trial is to assess the potential effectiveness of Progressive muscle relaxation technique (PMRT) vs Muscle energy technique (MET) as an intervention for releasing trigger points in SCM and upper trapezius in prolonged computer users. The study will be conducted in a workplace setting, where desk-type computer users are expected to regularly engage in their professional activities for ≥ 6 hours throughout the day, intermittently. This study will be conducted at the Outpatient Physiotherapy department of Sindh Institute of Physical Medicine and Rehabilitation, Karachi among 60 patients with nonspecific chronic neck pain on the basis of non-probability purposive sample technique. After taking informed consent, all participants will be randomly allocated into two groups through a investigator (blinded) the same investigator will be screening the individuals, doing baseline assessment, and post treatment assessment while another investigator will be providing intervention. Group 1 will receive Progressive muscle relaxation technique while Group 2 will receive Muscle Energy Technique on sternocleidomastoid and upper trapezius bilaterally. Patients will also be blinded. A total of 12 sessions will be provided. Outcomes will be assessed at baseline and post treatment after 2 weeks intervention.",[298,29],[399,400,401,402,112,249,403,404,405],"chronic pain","Computer user","Muscle relaxation","Progressive muscle relaxation,","Sternocleidomastoid muscle","Trapezius","neck pain musculoskeletal","2026-01-06",{"date":408,"type":44},"2026-01-08",{"date":410,"type":44},"2025-04-22",{"date":412,"type":23},"2026-04-30",{"name":414,"class":51},"IQRA University",{"id":416,"slug":417,"hasResults":12,"nctId":418,"briefTitle":419,"officialTitle":420,"acronym":4,"eligibilityCriteria":421,"healthyVolunteers":12,"sex":18,"minAge":422,"maxAge":423,"enrollmentInfo":424,"targetDuration":4,"studyType":24,"phases":425,"briefSummary":426,"conditions":427,"keywords":428,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":434,"lastUpdatePostDateStruct":435,"startDateStruct":437,"completionDateStruct":439,"leadSponsor":441,"locationsCount":52},"100618179","effects-of-post-isometric-relaxation-as-compared-to-post-isometric-stretching-muscle-energy-technique-in-the-management-of-neck-pain-a-randomized-controlled-trial-100618179","NCT07328256","Effects of Post Isometric Relaxation as Compared to Post Isometric Stretching Muscle Energy Technique in the Management of Neck Pain: a Randomized Controlled Trial","Effects of Post Isometric Relaxation as Compared to Post Isometric Stretching Muscle Energy Technique in the Management of Neck Pain","Inclusion Criteria: • Age ranging from 19-44 years old\n\n* Both gender\n* With sub-acute or chronic neck pain for at least 4 to 12 weeks\n* Pain intensity on NPRS ranging 4-8\n* Limitation on neck movement\n\nExclusion Criteria:\n\n* • Positive history of fracture\n\n  * Surgery in the cervical region\n  * Any sort of physical trauma in the cervical region in the last 12 months\n  * Thoracic Outlet syndrome\n  * Cervical radiculopathy\n  * Cervical myelopathy\n  * Cervical spondylosis\n  * Cervical syringomyelia\n  * Any systemic disorder including malignancy or inflammatory and rheumatic disorders\n  * Infection\n  * Vascular syndromes such as vertebrobasilar insufficiency (VBI).","19 Years","44 Years",{"count":84,"type":23},[26],"This study aims to compare the effects of post-isometric relaxation (PIR) and post isometric stretching (PIS) techniques on reducing neck pain, improving range of motion, and decreasing neck disability in individuals with neck pain. A randomized controlled trial will be conducted with 50 participants, who will be randomly assigned to one of two groups: one receiving PIR and the other receiving PIS. A single-blind method will be used, meaning the participants will not know which group they belong to. Participants will be selected based on specific criteria related to neck pain and will then be randomly allocated to the PIR or PIS group. Initially, all participants will receive two standard treatments: Transcutaneous Electrical Nerve Stimulation (TENS) and hot pack application. After these treatments, one group will undergo post-isometric relaxation (PIR), which involves 3-5 repetitions of muscle contraction and relaxation, conducted over five consecutive sessions. The other group will receive post-isometric stretching (PIS), which involves stretching after muscle contraction and relaxation, also administered over five consecutive sessions. At the end of the intervention, pain, range of motion, and neck disability will be measured. Pain will be assessed using a standardised pain scale, range of motion will be measured with a goniometer or other appropriate tools, and neck disability will be evaluated using the Neck Disability Index (NDI). Statistical analysis will be performed to compare the effectiveness of PIR and PIS in terms of pain reduction, range of motion improvement, and decreased neck disability.",[29],[429,430,29,431,432,433],"Subacute neck pain","Neck Muscles","Pain Management","Muscle Relaxation","Isometric Contraction","2025-12-26",{"date":436,"type":44},"2026-01-09",{"date":438,"type":44},"2025-01-15",{"date":440,"type":23},"2026-12-15",{"name":442,"class":51},"Foundation University Islamabad",{"id":444,"slug":445,"hasResults":12,"nctId":446,"briefTitle":447,"officialTitle":448,"acronym":449,"eligibilityCriteria":450,"healthyVolunteers":12,"sex":18,"minAge":451,"maxAge":452,"enrollmentInfo":453,"targetDuration":4,"studyType":24,"phases":454,"briefSummary":455,"conditions":456,"keywords":457,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":463,"lastUpdatePostDateStruct":464,"startDateStruct":466,"completionDateStruct":468,"leadSponsor":470,"locationsCount":52},"100602219","vacuum-massage-vs-tactile-massage-for-the-treatment-of-chronic-neck-pain-100602219","NCT07120659","Vacuum Massage vs Tactile Massage for the Treatment of Chronic Neck Pain","Vacuum Massage vs Tactile Massage for the Treatment of Chronic Neck Pain: A Randomized Controlled Pilot Study Investigating Pain Mechanisms.","MeCNeck","Inclusion Criteria:\n\n* suffer from non-specific neck pain persisting at least 3 months\n* mean pain intensity ≥ 50 on a 0-100 mm visual analogue scale (NRS) with \"0\" meaning \"no pain\" and \"100\" meaning \"worst pain imaginable\"\n\nExclusion Criteria:\n\n* neurological symptoms\n* having had a vertebral column surgery less than 12 months prior to the study,\n* have received TENS, acupuncture, osteopathy, or a chiropractic maneuver or infiltration at the area within 4 weeks prior to the inclusion in the study\n* suffer from a congenital deformation of the spine.","21 Years","75 Years",{"count":394,"type":23},[26],"Chronic pain significantly impacts individuals and society, with about 30% of Norwegian adults affected, making it the leading cause of long-term sick leave and disability benefits. Concerns over addiction to pain medications highlight the need for non-pharmacological treatments, though many such therapies, often complementary or alternative, are not widely available in conventional healthcare. Unclear biomechanisms of these therapies pose challenges for clinical trials and acceptance.\n\nThis pilot study aims to explore the effects of two types of massage-cupping massage (CM, intense) and tactile massage (TM, soft)-on chronic neck pain, focusing on their mechanisms of action. Quantitative sensory testing (QST) will be used as a biomarker to assess changes in the pain pathway. A previous feasibility study on CM and QST conducted in Germany informs this research.\n\nThe study will recruit 60 patients with chronic neck pain, randomized to CM or TM, with six weekly treatment sessions. QST will be measured before and after treatment to understand therapy-induced changes in the pain pathway. Findings will help tailor massage therapies to individual needs, improve clinical trial quality, and promote the integration of non-pharmacological treatments into conventional care, benefiting a large population in need.",[29],[249,458,459,460,461,462],"massage","soft touch massage","vacuum massage","cupping","quantitative sensory testing QST","2025-12-10",{"date":465,"type":44},"2025-12-11",{"date":467,"type":44},"2025-10-27",{"date":469,"type":23},"2030-12-31",{"name":471,"class":51},"University of Tromso",{"id":473,"slug":474,"hasResults":12,"nctId":475,"briefTitle":476,"officialTitle":477,"acronym":478,"eligibilityCriteria":479,"healthyVolunteers":266,"sex":18,"minAge":320,"maxAge":368,"enrollmentInfo":480,"targetDuration":4,"studyType":24,"phases":482,"briefSummary":483,"conditions":484,"keywords":486,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":488,"lastUpdatePostDateStruct":489,"startDateStruct":491,"completionDateStruct":493,"leadSponsor":495,"locationsCount":52},"100580308","effects-of-schroth-based-exercise-on-kyphosis-angle-muscle-strength-balance-pain-and-quality-of-life-in-hyperkyphosis-with-chronic-neck-pain-100580308","NCT06835608","Effects of Schroth-Based Exercise on Kyphosis Angle, Muscle Strength, Balance, Pain, and Quality of Life in Hyperkyphosis With Chronic Neck Pain","Effects of Schroth-Based Three-Dimensional Exercise Program on Angle of Kyphosis, Muscle Strength, Balance, Pain, and Quality of Life in Patients With Postural Hyperkyphosis With Chronic Neck Pain","Kyphosis","Inclusion Criteria:\n\n* Thoracic kyphosis angle \\> 45 degrees,\n* Aged between 20 and 50 years,\n* Have neck pain for more than 3 months,\n* Neck pain visual analogue scale \\> 3,\n* Not being treated for postural kyphosis in the last 6 months,\n* Has no systemic disease\n\nExclusion Criteria:\n\n* History of trauma or surgery on spinal joints,\n* Participants with rheumatological and metabolic disorders,\n* Participants with congenital postural deformity and scoliosis",{"count":481,"type":23},52,[26],"The normal thoracic kyphosis angle of the spine is 20-40°, however, an angle of more than 40° is referred to as postural kyphosis, increased kyphosis or hyperkyphosis. Although postural kyphosis negatively affects individuals' general health status, physical performance, and quality of life, there is still no standardized protocol for correcting the thoracic kyphosis angle. Conservative treatment approaches such as postural training and exercises, manual therapy, postural corrective kinesiotaping, and orthotic use have been recommended for managing increased thoracic kyphosis. While numerous studies have demonstrated the effectiveness of three-dimensional exercise programs in the treatment of scoliosis, research examining their impact on kyphosis remains considerably limited.Nevertheless, the potential of these exercises to promote neuromuscular reorganization suggests that they may be similarly effective in individuals with thoracic kyphosis. This randomized controlled trial aims to evaluate the effects of a Schroth-based three-dimensional exercise program on kyphosis angle, trunk muscle strength, balance, pain, and quality of life in individuals with postural hyperkyphosis and chronic neck pain.",[485,29],"Postural Kyphosis",[487,249],"postural hyperkyphosis","2025-12-02",{"date":490,"type":44},"2025-12-03",{"date":492,"type":44},"2025-02-25",{"date":494,"type":23},"2026-08-23",{"name":496,"class":51},"Baskent University",{"id":498,"slug":499,"hasResults":12,"nctId":500,"briefTitle":501,"officialTitle":502,"acronym":4,"eligibilityCriteria":503,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":82,"enrollmentInfo":504,"targetDuration":4,"studyType":24,"phases":506,"briefSummary":507,"conditions":508,"keywords":509,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":515,"lastUpdatePostDateStruct":516,"startDateStruct":517,"completionDateStruct":519,"leadSponsor":520,"locationsCount":52},"100613005","effects-of-a-multimodal-telerehabilitation-program-in-patients-with-chronic-non-specific-neck-pain-100613005","NCT07260955","Effects of a Multimodal Telerehabilitation Program in Patients With Chronic Non-Specific Neck Pain.","Effects of a Multimodal Telerehabilitation Program in Patients With Chronic Non-Specific Neck Pain: Randomized Clinical Trial.","Inclusion Criteria:\n\n* Non-specific neck pain for at least the last 12 weeks.\n* Pain intensity equal to or greater than 4 on the visual analog scale (VAS).\n* Mild-moderate disability in the Neck Disability Index.\n* Not reaching phase 2 in Craniocervical flexion test.\n* Availability and skill to do video calls.\n* Understanding Spanish.\n\nExclusion Criteria:\n\n* Other type of neck pain.\n* Previous neck surgery.\n* Diagnosed metabolic diseases.\n* Red flags (infection, tumors, rheumatic arthritis, or cardiovascular disease).\n* History of cardio-respiratory disease that contraindicates high-intensity exercise.\n* Fibromyalgia\n* Pregnancy\n* Physiotherapeuthic treatment continued in the last 3 month.",{"count":505,"type":23},54,[26],"The purpose of this study is to evaluate the clinical results in pain intensity, neck disability, range of motion, endurance deep cervical muscles, forward head position and kinesiophobia through thoracic spine mobility, deep neck muscles and thoracic strength training and pain education protocol versus a thoracic spine mobility, thoracic strength training and pain education protocol in patients with chronic non-specific neck pain.",[29,30],[510,511,512,513,514],"Neck muscles","Chronic neck pain","Telerehabilitation","Exercise therapy","Pain education","2025-11-21",{"date":490,"type":44},{"date":518,"type":23},"2025-12",{"date":156,"type":23},{"name":521,"class":51},"Universitat Internacional de Catalunya",{"id":523,"slug":524,"hasResults":12,"nctId":525,"briefTitle":526,"officialTitle":527,"acronym":4,"eligibilityCriteria":528,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":82,"enrollmentInfo":529,"targetDuration":4,"studyType":24,"phases":530,"briefSummary":531,"conditions":532,"keywords":533,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":542,"lastUpdatePostDateStruct":543,"startDateStruct":545,"completionDateStruct":547,"leadSponsor":549,"locationsCount":52},"100607476","virtual-reality-program-for-managing-chronic-neck-pain-100607476","NCT07189052","Virtual Reality Program for Managing Chronic Neck Pain","Effects of a Virtual Reality-Based Rehabilitation Program on Pain and Function in Individuals With Chronic Neck Pain","Inclusion Criteria:\n\n* Age 18-65 years\n* Diagnosis of chronic neck pain (≥ 6 months duration)\n* Ability to participate in rehabilitation sessions\n* Willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Previous adverse experience with virtual reality\n* Photophobia (UPSIS-12 score \\> 12)\n* Migraine (≥ 2 positive responses on ID-Migraine questionnaire)\n* Presence of any neurological deficit\n* History of spinal surgery\n* Medical conditions interfering with participation, including orthopedic, inflammatory, cardiovascular, rheumatologic, or vestibular disorders\n* Pregnancy\n* Epilepsy or other neurological conditions causing photosensitivity\n* Congenital spinal cord malformations",{"count":5,"type":23},[26],"The goal of this clinical trial is to find out if a virtual reality-based rehabilitation program developed by our team can help people with chronic neck pain.\n\nThe main questions it aims to answer are:\n\n* Does the VR program reduce neck pain?\n* Does it improve daily function and quality of life?\n\nParticipants will:\n\n* Take part in a supervised virtual reality exercise program for 8 weeks, attending 3 sessions per week (24 sessions in total).\n* Each session will last about 45 minutes.\n* Complete tests and questionnaires about their pain, disability, and overall well-being before and after the program.",[29],[534,535,536,537,538,539,540,541],"virtual reality","serious gaming","chronic","neck","pain","rehabilitation","conventional","technologic","2025-09-24",{"date":544,"type":44},"2025-09-29",{"date":546,"type":23},"2025-10-25",{"date":548,"type":23},"2027-10-28",{"name":339,"class":51},{"id":551,"slug":552,"hasResults":12,"nctId":553,"briefTitle":554,"officialTitle":555,"acronym":4,"eligibilityCriteria":556,"healthyVolunteers":266,"sex":18,"minAge":19,"maxAge":82,"enrollmentInfo":557,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":559,"conditions":560,"keywords":561,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":542,"lastUpdatePostDateStruct":568,"startDateStruct":569,"completionDateStruct":570,"leadSponsor":572,"locationsCount":52},"100607550","virtual-reality-application-for-assessing-neck-movement-and-position-sense-100607550","NCT07190014","Virtual Reality Application for Assessing Neck Movement and Position Sense","Investigation of the Effects of a Virtual Reality Application Developed for the Assessment of Cervical Joint Range of Motion and Joint Position Sense","Inclusion Criteria:\n\n* Chronic Neck Pain (CNP) participants\n\n  * Age 18-65. \n  * ≥ 6 months of neck pain. \n  * Willing to participate (informed consent). \n\nHealthy volunteers\n\n* Age 18-65. \n* No neck pain complaints. \n* Willing to participate (informed consent). \n\nExclusion Criteria:\n\n* Prior adverse virtual reality experience. \n\n  * Photophobia: UPSIS-12 score \\> 12. \n  * Migraine screen: ≥2 \"yes\" on ID-Migraine. \n  * Any neurological deficit. \n  * History of spinal surgery. \n  * Medical conditions that could interfere with participation: orthopedic, inflammatory, cardiovascular, rheumatologic, or vestibular problems. \n  * Pregnancy.",{"count":558,"type":23},58,"The goal of this observational study is to examine whether a virtual reality application developed by our team can be used to evaluate cervical range of motion (ROM) and joint position sense (JPS) in individuals with chronic neck pain.\n\nThe main questions it aims to answer are:\n\n* Does the virtual reality application provide reliable measurements of cervical ROM?\n* Does the application accurately assess cervical JPS when compared with a standard clinical tool (Cervical Range of Motion device, CROM)?\n\nResearchers will compare results from the VR application with results from the CROM device to see if the two methods give similar outcomes.\n\nParticipants will:\n\n* Complete a demographic and clinical evaluation.\n* Perform standardized neck movements (flexion, extension, left\u002Fright lateral flexion, left\u002Fright rotation).\n* Be assessed using both the CROM device and the VR application for ROM and JPS.",[29],[534,112,538,399,562,563,564,565,566,567],"evaluation","range of motion","joint position sense","proprioception","application","technologic rehabilitation",{"date":544,"type":44},{"date":546,"type":23},{"date":571,"type":23},"2026-07-30",{"name":339,"class":51},{"id":574,"slug":575,"hasResults":12,"nctId":576,"briefTitle":577,"officialTitle":577,"acronym":4,"eligibilityCriteria":578,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":59,"enrollmentInfo":579,"targetDuration":4,"studyType":24,"phases":581,"briefSummary":582,"conditions":583,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":584,"lastUpdatePostDateStruct":585,"startDateStruct":587,"completionDateStruct":589,"leadSponsor":591,"locationsCount":52},"100606713","additional-effects-of-semispinalis-cervicis-strengthening-with-craniocervical-flexion-training-on-chronic-neck-pain-100606713","NCT07179133","Additional Effects of Semispinalis Cervicis Strengthening With Craniocervical Flexion Training on Chronic Neck Pain","Inclusion Criteria:\n\n* Adults aged 18 to 35.\n* Chronic nonspecific Neck Pain persisting for more than 3 months.\n* Willingness to participate and and signed an informed consent form.\n* Self reported neck pain intensity greater than and equal to 3 on 11 point numerical pain scale.\n\nExclusion Criteria:\n\n* Recent neck injuries and surgeries.\n* Several medical conditions like Hypertension, RA and Cardiovascular Diseases.\n* Significant psychiatric disorders.",{"count":580,"type":23},42,[26],"Chronic neck pain affects 30-50% of individuals annually and is a leading cause of disability, often linked to muscle imbalances and compensatory over activation of superficial muscles. While craniocervical flexion trainning (CCFT) improves neuromuscular control and reduces pain, limited researches has examined the additional benefits of semispinalis cervicis strengthening. This randomized controlled trial, conducted at Fauji Foundation Hospital and Foundation University College of Physical Therapy will assess the effects of combining semispinalis cervicis strengthening with CCFT on pain, cervical erange of motion, muscle strength and functional disability. Participants will be randomly assigned to either CCFT alone or CCFT with semispinalis cervicis strengthening, performed three times per week for four weeks. Data will be collected at baseline, mid study (week 2) and end of study (week 4) using the Numeric pain rating scale, Goniometer, Sphygmomanometer and Nexk disability index. This study addresses a research gap by exploring deep cervical extensors strengthening alongside CCFT, potentially improving rehabilitation strategies for pain relief, cervical stability and functional recovery.",[29],"2025-09-17",{"date":586,"type":44},"2025-09-23",{"date":588,"type":23},"2025-09-30",{"date":590,"type":23},"2026-11-01",{"name":442,"class":51},{"id":593,"slug":594,"hasResults":12,"nctId":595,"briefTitle":596,"officialTitle":597,"acronym":4,"eligibilityCriteria":598,"healthyVolunteers":12,"sex":599,"minAge":19,"maxAge":600,"enrollmentInfo":601,"targetDuration":4,"studyType":24,"phases":602,"briefSummary":603,"conditions":604,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":606,"lastUpdatePostDateStruct":607,"startDateStruct":609,"completionDateStruct":610,"leadSponsor":611,"locationsCount":52},"100593333","tech-assisted-exercise-training-in-chronic-neck-pain-100593333","NCT07005076","Tech-Assisted Exercise Training in Chronic Neck Pain","Investigation of the Effects of Technology-Assisted Exercises in Individuals With Chronic Neck Pain","Inclusion Criteria:\n\n* Non-specific neck pain diagnosis\n* Having neck pain persisting for at least 3 months\n* Having the ability to speak and comprehend Turkish fluently\n* A pain score of 3 or higher according to the Numerical Rating Scale\n* A score of 5 or higher on the Neck Disability Index\n\nExclusion Criteria:\n\n* Having a history of spinal surgery.\n* Having an additional musculoskeletal disorder affecting the cervical region and upper extremities (e.g., scoliosis, rheumatoid arthritis, fibromyalgia, etc.).\n* Receiving physical therapy and\u002For other treatments for any reason within the last 6 months.\n* Having a diagnosed psychiatric disorder.\n* Having a vestibular pathology.\n* Having visual problems despite using visual aids.\n* Being pregnant.\n* Having a neurological deficit that may affect balance.\n* Discontinuing or being unable to complete the treatment process.","FEMALE","59 Years",{"count":580,"type":23},[26],"In this study, women with chronic neck pain residing in Afyonkarahisar, Turkey, will participate in an exercise-based intervention. Both the control and experimental groups will engage in conventional exercise programs; however, the experimental group will also receive an additional technology-assisted exercise program. It is anticipated that these interventions will positively impact participants' daily living activities and functional abilities. The study aims to assess whether the inclusion of technology-supported exercises leads to superior outcomes compared to conventional exercises alone. The findings are expected to provide valuable evidence on the effectiveness of integrating technology-assisted exercise programs into physiotherapy and rehabilitation practices for women with chronic neck pain.",[29,605],"Exercise Training Therapy","2025-05-27",{"date":608,"type":44},"2025-06-05",{"date":335,"type":44},{"date":518,"type":23},{"name":612,"class":51},"Afyonkarahisar Health Sciences University",{"id":614,"slug":615,"hasResults":12,"nctId":616,"briefTitle":617,"officialTitle":617,"acronym":4,"eligibilityCriteria":618,"healthyVolunteers":12,"sex":18,"minAge":320,"maxAge":368,"enrollmentInfo":619,"targetDuration":4,"studyType":24,"phases":620,"briefSummary":621,"conditions":622,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":492,"lastUpdatePostDateStruct":623,"startDateStruct":625,"completionDateStruct":627,"leadSponsor":629,"locationsCount":52},"100559346","comparison-of-efficiency-of-interferential-current-application-methods-in-chronic-neck-pain-100559346","NCT06562933","Comparison of Efficiency of Interferential Current Application Methods in Chronic Neck Pain","Inclusion Criteria:\n\n* Patients with chronic neck pain lasting at least 3 months\n* Ages between 20 and 50 years\n\nExclusion Criteria:\n\n* Patients with inflammatory or infectious diseases and those with radiculopathy or myelopathy symptoms\n* Patients for whom electrotherapy is contraindicated (e.g., those with pregnancy, neurological conditions such as epilepsy, inner ear hearing aids, arrhythmias, pacemakers, active infections, skin lesions, etc.)\n* Individuals with a history of malignancy, major surgery, or previous trauma\n* Individuals who have received physical therapy within the last year\n* Patients whose evaluation could not be completed for any reason\n* Patients who do not wish to complete their evaluations for any reason",{"count":394,"type":23},[26],"The aim of this study is to evaluate the effects of Interferential Current Therapy on pain, disability, and quality of life in patients with chronic neck pain and to compare the effects of applying Interferential Current Therapy with vacuum electrodes versus carbon-silicon pad electrodes.",[29],{"date":624,"type":44},"2025-02-26",{"date":626,"type":44},"2024-08-01",{"date":628,"type":23},"2025-04-01",{"name":630,"class":51},"Abant Izzet Baysal University",{"id":632,"slug":633,"hasResults":12,"nctId":634,"briefTitle":635,"officialTitle":636,"acronym":637,"eligibilityCriteria":638,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":639,"targetDuration":4,"studyType":62,"phases":4,"briefSummary":640,"conditions":641,"keywords":644,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":652,"lastUpdatePostDateStruct":653,"startDateStruct":655,"completionDateStruct":657,"leadSponsor":659,"locationsCount":52},"100573544","reliability-of-mri-and-ultrasound-in-cervical-epidural-needle-depth-estimation-100573544","NCT06747663","Reliability of MRI and Ultrasound in Cervical Epidural Needle Depth Estimation","Reliability of MRI and Ultrasound in Predicting Needle Depth During Cervical Epidural Injections: a Methodological Observational Study","CERV-MRI-USG","Inclusion Criteria:\n\nAge ≥ 18 years, Diagnosed with chronic cervical pain, Referred for cervical epidural steroid injection, Patients capable of providing informed consent.\n\nExclusion Criteria:\n\nAge \\\u003C 18 years, Pregnancy or breastfeeding, History of coagulation disorders or use of anticoagulants, Severe systemic infections or local infections at the injection site, Known allergy to steroids or local anesthetics, Uncontrolled diabetes mellitus, Patients with spinal tumors or significant spinal deformities, Previous cervical spine surgery, Cognitive impairment preventing informed consent or follow-up participation.",{"count":268,"type":23},"This study aims to evaluate the reliability of magnetic resonance imaging (MRI) and ultrasound (USG) in predicting needle depth during cervical epidural injections, compared to fluoroscopy. The goal is to identify alternative imaging methods that reduce radiation exposure while maintaining procedural accuracy and patient safety.",[29,642,643],"Radicular Pain","Cervical Epidural Injection",[645,646,647,648,649,650,651],"Cervical Epidural Steroid Injection","Needle Depth Estimation","Ultrasound Guidance","MRI Guidance","Fluoroscopy","Radiation Exposure","Chronic Pain Management","2024-12-18",{"date":654,"type":44},"2024-12-24",{"date":656,"type":23},"2025-01",{"date":658,"type":23},"2025-07",{"name":660,"class":51},"Damla Yürük"]