[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-obstructive-airways-disease-exacerbated\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-obstructive-airways-disease-exacerbated":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":4,"enrollmentInfo":16,"targetDuration":4,"studyType":19,"phases":20,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100619698","examining-the-effectiveness-of-single-limb-exercise-training-for-copd-patients-during-exacerbation-periods-100619698",false,"NCT07348003","Examining the Effectiveness of Single-Limb Exercise Training for COPD Patients During Exacerbation Periods","Inclusion Criteria:\n\nHospital admission due to an acute COPD exacerbation.\n\nNot currently enrolled in an active pulmonary rehabilitation program.\n\nAbsence of any additional neurological disorders.\n\nExclusion Criteria:\n\nHeart failure classified as New York Heart Association (NYHA) Class III or IV. Unstable mental status (indicated by a Mini-Mental State Examination (MMSE) score of 24).\n\nHistory of major surgery within the last three months. Presence of malignancies.","ALL",{"count":17,"type":18},30,"ESTIMATED","INTERVENTIONAL",[21],"NA","Resistance exercise applications during acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) are employed to enhance functional capacity and prevent muscle atrophy by increasing muscle strength.\n\nOwing to the limited cardiorespiratory reserve of COPD patients, single-limb exercises are better tolerated compared to traditional bilateral exercises. A study conducted by Vogiatzis et al. (2009) indicated that single-leg exercises require lower ventilation and result in more efficient oxygen consumption than bilateral exercises. This physiological advantage may be effective in reducing muscle weakness by increasing exercise endurance in COPD patients with restricted respiratory capacity.\n\nThe present study aims to demonstrate that single-limb resistance exercise is an effective rehabilitation method for increasing functional exercise capacity in patients during COPD exacerbations compared to a control group. Furthermore, the therapeutic effects of single-limb resistance exercises on dyspnea perception, fatigue, anxiety, and depression will be established. The study will also show that these exercises are both feasible and safe within rehabilitation protocols during the exacerbation period.",[24],"Chronic Obstructive Airways Disease Exacerbated",[26,27,28],"copd","exacerbated","exercise","NOT_YET_RECRUITING","2026-01-09",{"date":32,"type":33},"2026-01-16","ACTUAL",{"date":35,"type":18},"2026-03-02",{"date":37,"type":18},"2027-09-25",{"name":39,"class":40},"Alper Kemal Gürbüz","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":15,"minAge":49,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":19,"phases":52,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":41},"100609419","digital-inhaler-use-in-obstructive-lung-disease-care-100609419","NCT07214337","Digital Inhaler Use in Obstructive Lung Disease Care","Feasibility, Adoption and Efficacy of Digital Inhaler in the Management of Obstructive Lung Disease","Inclusion Criteria:\n\n* Any sex\n* Over the age of 18 years.\n* Physician-diagnosed obstructive lung disease\n* Speak, read, and understand English.\n* The current study is a feasibility pilot. Based on the results of the study, future studies will include non-English speakers as well.\n* Able to understand study requirements and comply with study procedures.\n* Ability to operate a smartphone or tablet (for questionnaire and symptoms input).\n* Patients who use either a DPI or an MDI device as controller medications. Medications will not be changed by the study team.\n\nExclusion Criteria:\n\n* Physically disabled such that they are incapable of using digital devices or metered dose inhalers.\n* Suffer from any visual, hearing or cognitive impairment that cannot be corrected enough to operate the devices properly. Mild\u002Fmoderate vision loss and mild hearing loss may be included with appropriate corrective measures that do not affect the device usage.\n* Suffering from serious uncontrolled medical conditions that may interfere with study conduct.\n* Inability or unwillingness of the participant to give written informed consent.\n* Pregnant women (due to complicated physiology)\n* The current study is a feasibility pilot. Based on the results of the study, future studies will likely include pregnant patients as well.\n* Prisoners","18 Years",{"count":51,"type":18},20,[21],"This is a pilot study to evaluate the role digital inhaler technology on patients with obstructive lung disease in preventing admissions and exacerbation, as well as improving symptom control. The primary objective is to evaluate feasibility of study protocol, patient recruitment, and patient retention with goal recruitment of 20 participants, 60% recruitment success, and 60% retention rate for 6 months duration. The secondary objectives are the evaluation of patient admission rate, exacerbation rates, and symptoms control with use of digital inhaler technology The subject population will be patients with physician diagnosed obstructive lung disease.",[24,55],"Chronic Obstructive Airway Disease",[57,58,59,60,61,62,63],"Chronic Obstructive Airways Disease","COPD","COPD Exacerbation","Severe COPD","Moderate COPD","Severe Chronic Obstructive Airways Disease","Moderate Chronic Obstructive Airways Disease","2025-10-07",{"date":66,"type":33},"2025-10-09",{"date":68,"type":18},"2025-11-01",{"date":70,"type":18},"2027-06",{"name":72,"class":40},"Cedars-Sinai Medical Center"]