[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-overuse-musculoskeletal-injuries\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-overuse-musculoskeletal-injuries":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100457700","enhancing-voluntary-motion-in-broad-patient-populations-with-modular-powered-orthoses-100457700",false,"NCT05240014","Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses","Inclusion criteria for able-bodied, young participants will be:\n\n* Aged between 18 to 65 years\n* Weigh less than 250 lbs due to limitations in the design of the orthoses\n* Ability to lift and lower a 10 kg weight using the neutral-spine squat technique for 10 repetitions\n\nExclusion criteria for able-bodied, young adult participants will be:\n\n* Pregnant (self-report)\n* Any significant neuromuscular or musculoskeletal disorder that would interfere with the study\n* Prior history of chronic lower-back pain\n* Unable to walk for 20 minutes\n* History of any cardiovascular, vestibular, or visual diseases and\u002For impairments that may interfere with the study\n* Cognitive deficits that would impair their ability to give informed consent or impair their ability to follow simple instructions during the experiments. Cognitive deficits will be determined by a Mini-Mental State Examination (MMSE) score of \\\u003C22.\n* Adults with a known allergy to medical grade tape\n\nInclusion criteria for elderly participants will be:\n\n* Aged between 65 to 85 years\n* Weigh less than 250 lbs due to limitations in the design of the orthoses\n* Ability to walk 6 minutes without assistance from a person (may use walking aid)\n\nExclusion criteria for elderly participants will be:\n\n* Pregnant (self-report)\n* Significant pain due to arthritis or other joint problems that would limit their ability to walk\n* Any recent lower-extremity fracture (within 3 months)\n* Significant neurological (e.g., stroke), orthopedic, or cardiovascular disorder that may affect the ability to walk\n* Advised by a physician not to walk or exercise\n* Uncontrolled hypertension or diabetes\n* Cognitive deficits or visual impairment that would impair their ability to give informed consent or impair their ability to follow simple instructions during the experiments. Cognitive deficits will be determined by a Mini-Mental State Examination (MMSE) score of \\\u003C22.\n* Adults with a known allergy to medical grade tape",true,"ALL","18 Years","85 Years",{"count":20,"type":21},33,"ESTIMATED","INTERVENTIONAL",[24],"NA","The overall goal of this project is to develop modular, lower-limb, powered orthoses that fit to user-specific weakened joints and control force\u002Ftorque in a manner that enhances voluntary motion in broad patient populations. This project aims to establish feasibility of assisting different populations with these modular powered orthoses. The investigators hypothesize that assisting lower-limb musculature with modular powered orthoses will improve 1) lifting\u002Flowering posture in able-bodied subjects and 2) functional outcomes in elderly subjects.",[27,28,29],"Lower-limb Orthoses","Frailty\u002FSarcopenia","Chronic Overuse Musculoskeletal Injuries","RECRUITING","2025-07-15",{"date":33,"type":34},"2025-07-18","ACTUAL",{"date":36,"type":34},"2022-07-29",{"date":38,"type":21},"2026-09-21",{"name":40,"class":41},"University of Michigan","OTHER"]