[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-respiratory-failure-with-hypoxia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-respiratory-failure-with-hypoxia":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100535097","effect-of-high-flow-therapy-in-long-term-oxygen-therapy-100535097",false,"NCT06247397","Effect of HIgh-flow Therapy in Long-term Oxygen Therapy","Effect of HIgh-flow Therapy in Long-term Oxygen Therapy (HILOT): A Multicenter, Registry-based, Randomized Clinical Trial","HILOT","Inclusion Criteria:\n\n* Age 40 years or older\n* Ongoing LTOT: prescribed for at least 15 hours per day; and since at least 28 days as registered in Swedevox\n* COPD or ILD as main underlying reason for LTOT\n* Oxygen concentrator as stationary oxygen source in the home including night-time\n* Body mass index (BMI) \\\u003C 35 kg\u002Fm2\n\nExclusion Criteria:\n\n* Current or previous treatment with home HFOT\n* Current treatment with home mechanical ventilation\n* Current treatment with home CPAP\n* Hospitalized during the last 2 weeks\n* Current smoking or contact with flames\n* Self-reported average use of the LTOT \\\u003C 15h per day (24 hours)\n* PaCO2 (breathing air at rest) \\> 8 kPa\n* Strong clinical suspicion of obstructive sleep apnea (OSA) or obesity-related hypoventilation syndrome (OHS) (as judged by the responsible staff)\n* Inability to participate in the study procedures (as judged by the staff)\n* Not eligible for continuing LTOT due to other reason (as judged by the staff)\n* Expected survival less than 3 months (as judged by the staff)","ALL","18 Years",{"count":20,"type":21},310,"ESTIMATED","INTERVENTIONAL",[24],"NA","This is a registry-based, randomized, controlled clinical trial of the effect of added high-flow oxygen therapy (using the device Lumis HFT) during one year in people with long-term oxygen therapy (LTOT) for chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD).",[27,28,29],"Chronic Obstructive Pulmonary Disease Severe","Interstitial Lung Disease","Chronic Respiratory Failure With Hypoxia","RECRUITING","2025-05-15",{"date":33,"type":34},"2025-05-21","ACTUAL",{"date":36,"type":34},"2024-06-10",{"date":38,"type":21},"2028-12",{"name":40,"class":41},"Skane University Hospital","OTHER",2]