[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-stroke-patients\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-stroke-patients":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,19,0,[8,50,86,125,147,170,195,231,257,290,313,338,363,389,414,437,457,481,506],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100600317","respark---brain-q-for-chronic-stroke-100600317",false,"NCT07095920","RESPARK - Brain Q for Chronic Stroke","Frequency-tuned Electromagnetic Field Treatment to Facilitate Recovery of Patients With Chronic Stroke","Inclusion Criteria:\n\n1. Upper Extremity Fugl-Meyer Assessment score between 22-50 (inclusive) of impaired limb.\n2. Upper Extremity Fugl-Meyer Assessment score is within up to 3-point difference between Screening and Baseline visit.\n3. Age 18 to 80 years of age (inclusive).\n4. Stroke due to ischemia or to intracerebral hemorrhage.\n5. \\>6 months to 5 years from stroke onset.\n6. Box \\& Block Test score with affected arm is ≥1 block in 60 seconds.\n7. Able to sit with the investigational system for 40 consecutive minutes.\n8. Can follow a 3-step command, such as \"take the paper, fold it in half, and return it to me\", or a non-verbal equivalent.\n9. Willingness to participate in physical exercises during study intervention sessions.\n10. Availability of a relative or other caregiver that is able to participate in training and assist during treatment sessions at Brooks and home during the study duration.\n11. If female, not pregnant or breastfeeding or planning pregnancy during the study period.\n12. The subject is able to provide Informed consent.\n\nExclusion Criteria:\n\n1. Severe neglect impairment interfering with assessments or treatments.\n2. Severe depression, defined as Geriatric Depression Scale (GDS) Score \\>10\u002F15\n3. Presence of implanted or retained MR-incompatible devices or materials, or the presence of life-sustaining MR-compatible devices (e.g. pacemaker or internal cardiac defibrillator).\n4. Active epilepsy or currently taking anti-epileptic medication (indicated for the treatment of a seizure disorder), or any epileptic seizure in the last 5 years\n5. Botulinum toxin to the paretic arm: received in the prior 3 months OR expected before the 6-Month Visit\n6. Severe upper extremity spasticity, defined as presence of contracture or modified Ashworth Scale score ≥3 in either biceps or pectoralis\n7. Pre-existing neurological condition (e.g., Alzheimer's disease, Parkinson's disease, multiple sclerosis, traumatic brain injury, spinal cord injury) or physical limitation that would interfere significantly with the subject's participation in the study and\u002For confound neurological or functional evaluation.\n8. Significant visual disturbances, pre-existing or resulting from the index stroke, that cannot be corrected and that would interfere significantly with the subject's participation in the study and\u002For confound neurological or functional evaluation.\n9. Unstable serious illness\u002Fcondition (e.g., active cancer, severe heart failure, active major psychiatric condition) or life expectancy of less than 12 months.\n10. Alcohol abuse and\u002For illicit drug abuse in the past 6 months, which is likely to influence ability to fully participate in the trial.\n11. Participation in another trial that would conflict with the current study or clinical endpoint interference may occur.\n12. Active participation in an upper extremity rehabilitation program provided by a licensed provider within 4 weeks from the screening visit and until the primary endpoint visit.\n13. Employee of the Sponsor.\n14. Prisoner.","ALL","18 Years","80 Years",{"count":20,"type":21},25,"ESTIMATED","INTERVENTIONAL",[24],"NA","This trial tests a promising new intervention to promote post-stroke neural reorganization and functional recovery. The Q Therapeutic (BQ 3.0) is a wearable medical system that produces and delivers non-invasive, extremely-low-intensity and low-frequency, frequency-tuned electromagnetic fields in order to stimulate neuronal networks with the aim of reducing disability and promoting neurorecovery. This trial is a prospective, single-arm, open-label, single center clinical trial designed to evaluate the safety, feasibility, and efficacy of the Q Therapeutic (BQ 3.0) System in the rehabilitation of people with chronic stroke.",[27,28,29],"Stroke","Chronic Stroke Patients","Cerebrovascular Accident (CVA)",[31,32,33,34,35,36],"BrainQ","Electromagnetic Stimulation","upper extremity","rehabilitation","exercise","mobility","RECRUITING","2026-07-01",{"date":40,"type":41},"2026-07-02","ACTUAL",{"date":43,"type":41},"2025-08-27",{"date":45,"type":21},"2026-12",{"name":47,"class":48},"University of Florida","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":81,"leadSponsor":83,"locationsCount":49},"100640783","ktmp-enhanced-motor-rehabilitation-for-chronic-stroke-recovery-kulminate-pilot-100640783","NCT07631078","kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery (KULMINATE) Pilot","kTMP-Enhanced Motor Rehabilitation for Chronic Stroke Recovery","Inclusion criteria:\n\n1. Adults aged 18-80 years who have a history of an ischemic or hemorrhagic stroke ≥ 12 m prior to enrollment.\n2. Fugl-Meyer Assessment: Upper Extremity (FMA UE) score 20-50.\n3. Ability to communicate, understand, and give appropriate consent. Participants can follow two-step commands.\n4. Motor evoked potentials in a hand muscle when stimulating ipsilesional cortex with suprathreshold single-pulse TMS (MEP positive).\n\nExclusion criteria:\n\n1. Participants with moderate or severe cognitive impairment (MoCA \\\u003C 18).\n2. Participants with sensory deficits FMA-S \\\u003C 6\u002F12 (with proprioception \\\u003C 4\u002F8).\n3. Participants with severe apraxia (TULIA \\\u003C 5).\n4. Language impairment or behavioral disorder that interferes with their ability to adhere to the protocol or to provide informed consent.\n5. Individuals who have a serious uncontrolled medical condition, including but not limited to severe cardiovascular and cardiopulmonary disease.\n6. Pregnancy or plans to become pregnant during the study period.\n7. Botulinum toxin injections of the affected upper extremity within 3 months prior to onset of study.\n8. Severe spasticity of the affected upper limb (Modified Ashworth ≥ 4).\n9. Absolute contraindications related to non-invasive brain stimulation, including:\n\n9a) History of seizures in the last 12 months while taking anti-epilepsy medication 9b) Presence of any metal implants in the head (excluding the mouth), such as cortical stimulators and DBS, clips, coils, shunts, stents or skull plates, cochlear implants 9c) Permanent eye liner or head tattoos 9d) Implanted electronics such as pacemakers, defibrillators, intrathecal baclofen pumps or vagus nerve stimulator 9e) History of experiencing a serious adverse event during a previous transcranial magnetic stimulation (TMS) session",{"count":58,"type":21},12,[24],"kTMP, kilohertz transcutaneous magnetic perturbations, is a low intensity transcranial magnetic stimulation technique that will be used in this study to promote arm\u002Fhand rehabilitation in patients who have been disabled by stroke.",[27,28,62],"Arm Weakness as a Consequence of Stroke",[64,65,66,67,68,69,70,27,71,72,73,74,75,76],"kTMP","Ischemic Stroke","Hemorrhagic Stroke","Cortical Excitability","Plasticity","kilohertz Transcranial Magnetic Perturbation","Cerebrovascular Disorders","Chronic Stroke","Transcranial Magnetic Stimulation","Non-Invasive Brain Stimulation","Brain Disorders","Central Nervous System Disorders","Cardiovascular Disorders","2026-06-01",{"date":79,"type":41},"2026-06-05",{"date":38,"type":21},{"date":82,"type":21},"2028-08",{"name":84,"class":85},"Magnetic Tides","INDUSTRY",{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":91,"acronym":92,"eligibilityCriteria":93,"healthyVolunteers":11,"sex":16,"minAge":94,"maxAge":4,"enrollmentInfo":95,"targetDuration":4,"studyType":22,"phases":97,"briefSummary":98,"conditions":99,"keywords":105,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":49},"100574927","the-effect-of-non-invasive-brain-stimulation-rtms-on-hand-muscles-in-chronic-stroke-patients-100574927","NCT06765642","The Effect of Non-invasive Brain Stimulation rTMS on Hand Muscles in Chronic Stroke Patients.","Evaluation of 3 Patterned rTMS Stimulation Dosage on Corticospinal Excitability and Motor Learning in Stroke Patients","REALISE","Inclusion criteria:\n\n1. Age \\>=21 years old of any race or gender\n2. First-ever ischemic or hemorrhagic stroke (neuroimaging verified) at least 3 months from stroke onset\n3. Unilateral arm weakness measured by FM-UM scale \\\u003C= 62 out of 66\n4. Inducible rest motor threshold and testing motor threshold recorded from the affected first dorsal interosseous (FDI) muscle from the study subject\n\nExclusion criteria\n\n1. Bilateral strokes (infarcts and\u002For hematoma)\n2. Other co-existent neuromuscular disorders affecting upper extremity motor impairment.\n3. History of medically uncontrolled depression or other neuropsychiatric disorders despite medications either before or after a stroke that may affect the subject's ability to participate in the study.\n4. Uncontrolled hypertension despite medical treatment(s) at the time of randomization, defined as SBP≥185 mmHg or DBP≥110 mmHg (patient can be treated, reassessed and randomized later).\n5. Presence of any MRI\u002FrTMS risk factors including but not limited to:\n\n   1. an electrically, magnetically, or mechanically activated metallic or nonmetallic implant including cardiac pacemaker, intracerebral vascular clips or any other electrically sensitive support system.\n   2. a non-fixed metallic part in any part of the body, including a previous metallic injury to the eye.\n   3. history of seizure disorder before stroke or seizure after stroke.\n   4. preexisting scalp lesion or bone defect or hemicraniectomy.\n6. Concurrent enrollment in another interventional stroke recovery study.\n7. Concerns that the subject cannot comply with study procedures and visits.\n8. Pregnant individuals","21 Years",{"count":96,"type":21},26,[24],"The study is about using a brain stimulation technique called rTMS (Repetitive Transcranial Magnetic Stimulation) to help improve hand muscles in people who had a stroke. Researchers want to understand how this device can help stroke patients use their hands better.",[27,100,62,101,102,72,103,28,104],"Stroke Patients","Brain Stimulation","Transcranial Magnetic Stimulation Repetitive","Motor Learning","Chronic Stroke Survivors",[106,107,108,109,110,111,112,113,114,115],"stroke","arm weakness","arm weakness as a consequence of stroke","stroke patients","transcranial magnetic stimulation","transcranial magnetic stimulation repetitive","motor learning","chronic stroke","chronic stroke patients","chronic stroke survivors","2026-05-19",{"date":118,"type":41},"2026-05-22",{"date":120,"type":41},"2025-06-09",{"date":122,"type":21},"2027-04-30",{"name":124,"class":48},"Duke University",{"id":126,"slug":127,"hasResults":11,"nctId":128,"briefTitle":129,"officialTitle":130,"acronym":131,"eligibilityCriteria":132,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":133,"targetDuration":4,"studyType":22,"phases":135,"briefSummary":60,"conditions":136,"keywords":137,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":143,"leadSponsor":145,"locationsCount":49},"100614284","ktmp-in-chronic-stroke-100614284","NCT07277595","kTMP in Chronic Stroke","KTMP: A Novel Method of Non-invasive Brain Stimulation to Enhance Motor Function in Chronic Stroke Patients.","KULMINATE","Inclusion Criteria:\n\n* Adults age 18-80 years old who have had a stroke resulting in hemiplegia\n* Ability to communicate, understand, and give appropriate consent\n* Other criteria may apply\n\nExclusion Criteria:\n\n* Significant cognitive impairment\n* inability to adhere to the study protocol or provide informed consent\n* pregnancy\n* additional criteria may apply",{"count":134,"type":21},100,[24],[27,28,62],[110],"NOT_YET_RECRUITING","2026-05-01",{"date":141,"type":41},"2026-05-06",{"date":38,"type":21},{"date":144,"type":21},"2030-08-01",{"name":146,"class":48},"University of California, San Francisco",{"id":148,"slug":149,"hasResults":11,"nctId":150,"briefTitle":151,"officialTitle":151,"acronym":152,"eligibilityCriteria":153,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":154,"targetDuration":4,"studyType":22,"phases":155,"briefSummary":156,"conditions":157,"keywords":158,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":4},"100631333","the-safety-and-effectiveness-of-q-therapeutic-system-frequency-tuned-electromagnetic-field-treatment-in-facilitating-the-recovery-of-patients-with-chronic-stroke-100631333","NCT07499310","The Safety and Effectiveness of Q Therapeutic System, Frequency-tuned Electromagnetic Field Treatment in Facilitating the Recovery of Patients With Chronic Stroke.","RESPARK","Inclusion Criteria:\n\n* Be between ages 18-80\n* Have an score between 22-50 (inclusive) of impaired limb on the Fugl-Meyer Assessment for the Upper Extremity (FMA-UE), as determined by study staff\n* Have upper extremity function that is not changing much over time (as determined by study staff based on assessments I complete at screening and before treatment starts)\n* Have stroke due to ischemia or to intracerebral hemorrhage • Be \\>6 months to 5 years from stroke onset\n* Have a Box \\& Block Test score with affected arm is ≥1 block in 60 seconds at Baseline Visit\n* Be able to sit with the investigational System for 40 consecutive minutes\n* Be able to follow a 3-step command in English, such as \"take the paper, fold it in half, and return it to me\", or a non-verbal equivalent\n* Have the willingness to participate in physical exercises during study intervention sessions.\n* Be sure of the availability of a relative, friend, or other non-hired caregiver to be able to assist during program sessions and study visits, as needed\n\nExclusion Criteria:\n\n* Be younger than 18 years old or older than 80\n* Have implanted MR-incompatible devices or MR-incompatible retained objects (like shrapnel) or an implanted life-sustaining MR-compatible devices (such as a pacemaker or internal cardiac defibrillator)\n* Have conditions other than stroke, such as:\n\nA. Severe neglect impairment interfering with assessments or treatments. B. Severe depression, defined as GDS Score \\>10\u002F15 C. Active epilepsy or currently taking anti-epileptic medication (indicated for the treatment of a seizure disorder), or any epileptic seizure in the last 5 years.\n\nD. Severe upper extremity spasticity, defined as presence of upper extremity contracture or modified Ashworth Scale score ≥3 in either biceps or chest muscles.\n\nE. Pre-existing neurological condition (such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, traumatic brain injury, spinal cord injury) or physical limitation that would interfere significantly with my participation in the study and\u002For confound neurological or functional evaluation F. Unstable serious illness\u002Fcondition (such as active cancer, severe heart failure, active major psychiatric condition) or life expectancy of less than 12 months. significant visual disturbances, pre-existing or resulting from the index stroke, that cannot be corrected and that would interfere significantly with my participation in the study and\u002For confoundneurological or functional evaluation\n\n* Have alcohol abuse and\u002For drug abuse in the past 6 months, which is likely to influence ability to fully participate in the trial\n* Had active participation in an arm rehabilitation program with a therapist in the 4 weeks prior to the screening visit\n* Plan to have an arm rehabilitation program with a therapist between the screening visit and the assessment visit at 3-months\n* Be an employee of Kessler Foundation\n* Be a prisoner\n* Be pregnant or breastfeeding or planning pregnancy during the study period.\n* Have other conditions or circumstances that, in the opinion of the investigators, would affect the safety or effectiveness of the training in which I would participate",{"count":20,"type":21},[24],"This trial will test a promising new intervention to promote post-stroke neural reorganization and functional recovery. The overall aim is to identify a systematic, methodological approach to system fitting, training protocols, and optimization of collecting outcome measures.\n\nAim 1: Assess the safety of using the Q Therapeutic (BQ 3.0) System, including in-clinic and at- extremity rehabilitation training for individuals with chronic stroke, as determined by the number of adverse events. Device deficiencies will also be recorded to detect operational reliability.\n\nAim 2: Evaluate the effectiveness of the Q Therapeutic (BQ 3.0) System for individuals with chronic stroke in improving upper extremity function as determined by change in functional outcome measures after 3-month treatment, including in-clinic and at-home sessions.",[27,28],[159,33,34,160],"BrainQ Electromagnetic Stimulation","exercise mobility","2026-03-27",{"date":163,"type":41},"2026-03-30",{"date":165,"type":21},"2026-02",{"date":167,"type":21},"2026-12-31",{"name":169,"class":48},"Kessler Foundation",{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":174,"acronym":4,"eligibilityCriteria":175,"healthyVolunteers":11,"sex":16,"minAge":176,"maxAge":177,"enrollmentInfo":178,"targetDuration":4,"studyType":22,"phases":180,"briefSummary":181,"conditions":182,"keywords":183,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":4},"100627995","effect-of-interactive-games-based-hand-training-on-hand-dexterity-and-functional-outcome-in-patients-with-stroke-100627995","NCT07455877","Effect of Interactive Games Based Hand Training on Hand Dexterity and Functional Outcome in Patients With Stroke","Inclusion Criteria:\n\n1. Forty chronic ischemic stroke patients from both sexes.\n2. Their ages will range from 45 - 65 years old.\n3. Stroke duration between six months and two years.\n4. Spasticity grade of the upper limb is from 1+to 2 according to the Modified Ashworth scale.\n5. MMSE score \\> 24 to ensure adequate cognitive function for following instructions.\n6. Patients with at least 20° of wrist flexion\u002Fextension and at least 10° of finger flexion and extension of the paretic limb.\n7. Brunnstrom stages ≥ 4 were included\n8. Medically stable patients.\n\nExclusion Criteria:\n\n1. Other neurological disorders (e.g.: Multiple sclerosis, Parkinsonism…etc).\n2. Visual, auditory, and cognitive deficits.\n3. Patients with psychological or sever cognitive disorders.\n4. Patients with musculoskeletal problems (deformity or contracture).\n5. Medically unstable and uncooperative patients.","45 Years","65 Years",{"count":179,"type":21},40,[24],"This current study will be designed to determine the effect of smart tablets hand training applications on hand functions and functional outcome in patients with stroke. Tablet-based hand function training app with smart tablet exercises:\n\nPatients in the study group will receive 20 min of smart tablet active hand therapy. Patients in the study and control group will receive 30 min of conventional physical therapy program. This program consists of neurodevelopmental facilitation techniques organized specifically for each patient, range of motion exercises, strengthening exercises .\n\nIt includes the following functional tasks (reaching, grasping, lifting and placing objects).",[28],[106,184,185],"interactive games","hand training","2026-03-05",{"date":188,"type":41},"2026-03-09",{"date":190,"type":21},"2026-03-01",{"date":192,"type":21},"2026-07-25",{"name":194,"class":48},"Cairo University",{"id":196,"slug":197,"hasResults":11,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":201,"eligibilityCriteria":202,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":203,"targetDuration":4,"studyType":22,"phases":205,"briefSummary":206,"conditions":207,"keywords":210,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":221,"lastUpdatePostDateStruct":222,"startDateStruct":224,"completionDateStruct":226,"leadSponsor":228,"locationsCount":230},"100584143","personalised-health-motor-and-cognitive-assistance-system-for-rehabilitation-phrase-100584143","NCT06885502","Personalised Health Motor and Cognitive Assistance System for RehAbilitation (PHRASE)","Personalised Health Motor and Cognitive Assistance System for RehAbilitation (PHRASE): A Randomized Clinical Trial","PHRASE-2024","Inclusion Criteria:\n\n* Patients presenting an ischemic or intracerebral haemorrhagic stroke, ≥ 3 months post-stroke.\n* Age \\> 18 years old\n* Moderate to mild proximal upper limb motor impairment Medical Research Council Scale (MRC \\>2).\n* ARAT: \\\u003C50, inclusive, to avoid ceiling effects while allowing room for improvement.\n* Able to sit on a chair or a wheelchair to interact with the RGS system.\n* Minimal experience with smartphone technology based on the clinician's opinion\n* Willing to participate and agree to comply with the trial scheme and procedures\n* Must sign an Informed Consent Form (ICF) indicating that they understand the purpose and the procedures of the study.\n\nExclusion Criteria:\n\n* Presence of a condition or abnormality that, in the opinion of the investigator, would compromise the safety of the patient or the quality of the data.\n* Severe cognitive capabilities that prevent the execution of the study, evaluated by the MoCA \\\u003C 19 or based on the clinician's opinion.\n* Pre-stroke history of upper limb motor disability.\n* Unable to use the RGS independently, according to the clinician's observations, and needing more support from a caregiver to use the RGS.",{"count":204,"type":21},70,[24],"This study is a multicentric randomized controlled trial evaluating the effectiveness of digital technology, specifically a smartphone with integrated VR-and AR-based intervention, for at-home rehabilitation after stroke. The study focuses on combined motor and cognitive training for patients in the late subacute and chronic phases post-stroke. The intervention is provided through the Rehabilitation Gaming System application RGSapp, a goal-oriented, first-person virtual reality (VR) and augmented reality (AR) mobile application for upper limb rehabilitation. A total of seventy participants will be randomly assigned (1:1 ratio) to either the RGSapp intervention or conventional therapy\u002Fstandard of care for six weeks. The primary outcome is motor function improvement (upper limb), assessed using the Action Research Arm Test (ARAT). Secondary outcomes include changes in cognitive function, depression, usability, adherence, validity of remote assessments, and healthcare costs.",[27,208,28,209],"Stroke Rehabilitation","Post Stroke Recovery",[27,211,212,213,214,215,216,217,218,219,220],"ARAT","Motor rehabilitation","Stroke rehabilitation","Telemedicine","Virtual Reality (VR)","Augmented Reality (AR)","Cognitive rehabilitation","Rehabilitation at home","eHealth technology","upper limbs","2025-12-31",{"date":223,"type":41},"2026-01-06",{"date":225,"type":41},"2025-02-21",{"date":227,"type":21},"2026-06-30",{"name":229,"class":85},"Eodyne Systems SL",2,{"id":232,"slug":233,"hasResults":11,"nctId":234,"briefTitle":235,"officialTitle":236,"acronym":4,"eligibilityCriteria":237,"healthyVolunteers":11,"sex":16,"minAge":238,"maxAge":239,"enrollmentInfo":240,"targetDuration":4,"studyType":22,"phases":242,"briefSummary":243,"conditions":244,"keywords":245,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":247,"lastUpdatePostDateStruct":248,"startDateStruct":250,"completionDateStruct":252,"leadSponsor":254,"locationsCount":256},"100615500","neuropilates-and-otago-exercises-on-balance-posture-and-functional-independence-in-chronic-stroke-100615500","NCT07293416","Neuropilates and Otago Exercises on Balance, Posture and Functional Independence in Chronic Stroke","Comparative Effects of Neuropilates and Otago Exercises on Balance, Posture and Functional Independence in Individuals With Chronic Stroke","Inclusion Criteria:\n\n* Age 40-70 years\n* Both male and female\n* Chronic stroke, 6-18 months post-stroke\n* Stroke severity score \\>6 on NIHSS\n* MMSE ≥24\n\nExclusion Criteria:\n\n* • Symptoms of global or receptive aphasia\n\n  * Other neurological disorders: tumors, anoxia, TBI, neurodegenerative diseases, ataxia.\n  * Significant cardiorespiratory conditions\n  * Currently receiving other complementary interventions\n  * Severe motor impairment preventing safe participation","40 Years","70 Years",{"count":241,"type":21},32,[24],"This randomized clinical trial will be conducted at various physical therapy clinics of Faisalabad over a six-month period, enrolling a total of 32 participants selected through non probability convenience sampling technique. Participants will be randomly assigned to one of two groups: those undergoing Neuropilates and those performing Otago exercises, with each group consisting of 16 individuals. Assessments will utilize the TUG (Timed Up and Go) to evaluate balance, the Postural Assessment Scale for Stroke Patients (PASS) for posture, and the Functional Independence Measure (FIM) for functional independence. Pre-intervention assessments will establish baseline measures, followed by evaluations at 4 weeks, and post-intervention to track progress. Data analysis will be conducted using SPSS 26 software, allowing for a comprehensive comparison of the interventions' effectiveness. The findings from this study will contribute valuable insights for clinicians and rehabilitation specialists, enhancing therapeutic strategies to support chronic stroke patients in regaining their independence.",[28],[246],"Balance, Chronic Stroke, Functional Independence, Neuropilates, Otago exercises.","2025-12-08",{"date":249,"type":41},"2025-12-19",{"date":251,"type":21},"2025-12",{"date":253,"type":21},"2026-04-30",{"name":255,"class":48},"Riphah International University",3,{"id":258,"slug":259,"hasResults":11,"nctId":260,"briefTitle":261,"officialTitle":262,"acronym":263,"eligibilityCriteria":264,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":265,"targetDuration":4,"studyType":22,"phases":267,"briefSummary":268,"conditions":269,"keywords":273,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":281,"lastUpdatePostDateStruct":282,"startDateStruct":284,"completionDateStruct":286,"leadSponsor":288,"locationsCount":49},"100598573","effects-of-intermitted-theta-burst-stimulation-itbs-on-motor-recovery-of-upper-extremity-in-chronic-stroke-patients-100598573","NCT07073248","Effects of Intermitted Theta Burst Stimulation (iTBS) on Motor Recovery of Upper Extremity in Chronic Stroke Patients","Neuroplastic Changes and Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Upper and Lower Extremity in Chronic Stroke Patients","NIMBLE","Inclusion Criteria:\n\n* Age over 18\n* Chronic stroke (\\>6 months)\n* Residual hemiparesis FM-UE\\>17\n\nExclusion Criteria:\n\n* Metal implants\n* Epilepsy\u002Fseizures\n* Pregnancy\n* Claustrophobia (related to MRIs exams)\n* Severe cognitive impairment\n* Untreated or unstable depression\u002Fanxiety\n* Other disabilities prohibiting intensive physical training",{"count":266,"type":21},48,[24],"This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of upper extremity in the chronic phase after stroke.\n\nIt also seeks to explore the underlying mechanisms by investigating changes of functional and structural brain networks.",[27,270,271,272,28],"Hemiplegia","Hemiparesis After Stroke","Hand Functionality",[106,274,275,276,114,277,278,279,280],"iTBS","TMS","Motor cortex","hand dexterity","Hemiparesis","Transcrania Magnetic Stimulation","intermittent Theta Burst Stimulation","2025-11-20",{"date":283,"type":41},"2025-11-21",{"date":285,"type":21},"2025-11",{"date":287,"type":21},"2030-12",{"name":289,"class":48},"Danderyd Hospital",{"id":291,"slug":292,"hasResults":11,"nctId":293,"briefTitle":294,"officialTitle":262,"acronym":263,"eligibilityCriteria":295,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":296,"targetDuration":4,"studyType":22,"phases":298,"briefSummary":299,"conditions":300,"keywords":302,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":281,"lastUpdatePostDateStruct":308,"startDateStruct":310,"completionDateStruct":311,"leadSponsor":312,"locationsCount":49},"100598572","effects-of-intermittent-theta-burst-stimulation-itbs-on-motor-recovery-of-lower-extremity-in-chronic-stroke-patients-100598572","NCT07073235","Effects of Intermittent Theta Burst Stimulation (iTBS) on Motor Recovery of Lower Extremity in Chronic Stroke Patients","Inclusion Criteria:\n\n* Age over 18\n* Chronic stroke (\\>6 months)\n* Residual hemiparesis FAC ≥3\n\nExclusion Criteria:\n\n* Metal implants\n* Epilepsy\u002Fseizures\n* Pregnancy\n* Claustrophobia (related to MRIs exams)\n* Severe cognitive impairment\n* Untreated or unstable depression\u002Fanxiety\n* Other disabilities prohibiting intensive physical training",{"count":297,"type":21},56,[24],"This study aims to evaluate the effects and clinical feasibility of non-invasive brain stimulation protocols, specifically intermittent Theta Burst Stimulation, as part of rehabilitation interventions for motor recovery of lower extremity in the chronic phase after stroke.\n\nIt also seeks to explore the underlying mechanisms by investigating changes of functional and structural brain networks.",[27,271,28,270,301],"Ambulatory Difficulty",[106,274,275,303,304,305,306,307,278,280],"Trancranial Magnetic Stimulation","Cerebellum","Chronic stroke patients","Balance","Walking",{"date":309,"type":41},"2025-11-25",{"date":285,"type":21},{"date":287,"type":21},{"name":289,"class":48},{"id":314,"slug":315,"hasResults":11,"nctId":316,"briefTitle":317,"officialTitle":318,"acronym":4,"eligibilityCriteria":319,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":320,"targetDuration":4,"studyType":22,"phases":322,"briefSummary":323,"conditions":324,"keywords":325,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":330,"lastUpdatePostDateStruct":331,"startDateStruct":333,"completionDateStruct":335,"leadSponsor":336,"locationsCount":49},"100610356","walking-and-tscs-in-non-ambulatory-stroke-survivors-100610356","NCT07226518","Walking and tSCS in Non-ambulatory Stroke Survivors","Robot-assisted Gait Training and Transcutaneous Spinal Cord Stimulation in Chronic Non-ambulatory Stroke Survivors: Pilot RCT Trial","Inclusion Criteria:\n\n1. Age 18-80 years at time of consent\n2. All genders included.\n3. Chronic ischemic or hemorrhagic stroke \\>=6 months, with limited within-home comfortable walking speed \\\u003C= 0.49 m\u002Fs and unable to walk independently in community (FAC \\\u003C= 3)\n4. Able to communicate with investigators, follow 2-step command, and correctly answer consent comprehension questions in English.\n5. Currently not participating in treadmill walking exercises or exercises involving weight-bearing activities.\n6. Have physicians' approval for exercise and be in a stable medical condition\n\nExclusion Criteria:\n\n1. Hospitalization for cardiac or pulmonary disease within the past 3 months\n2. Have musculoskeletal disorders that prevent the participant from participating in the exercise\n3. Blood pressure higher than 200\u002F110 mm Hg\n4. Significant ataxia or unilateral spatial neglect (score of 2 on NIH stroke scale item 7 or 11)\n5. Reported pain that limits or interferes with activities of daily living and physical activity\u002Fexercise\n6. Diagnosis of other neurological diseases (multiple sclerosis, Alzheimer's disease, Parkinson's disease)\n7. Diagnosis of severe depression (HADS score 15-21)\n8. Unable to speak or understand English, and travel to the research laboratory.\n9. Contraindications to tSCS and TMS",{"count":321,"type":21},20,[24],"Rehabilitation interventions commonly used for stroke survivors include task-specific training, balance and strength exercises, and the use of assistive devices to enhance mobility and independence. Advanced technologies, such as body-weight-supported treadmill systems and robotic devices, may be employed when appropriate. Current rehabilitation therapies for stroke survivors are moderately effective with a limited effect size, especially in stroke survivors with severe impairment. Novel therapies, such as transcutaneous spinal cord stimulation (tSCS), may further improve outcomes in the target population. This pilot study will allow us to examine the feasibility and gather pilot data on a combined intervention of assistive gait training and tSCS in non-ambulatory stroke survivors.",[104,28,27],[326,327,328,329],"stroke gait rehabilitation","Transcutaneous spinal cord stimulation","Non invasive spinal cord stimulation","Robot assisted gait training","2025-11-07",{"date":332,"type":41},"2025-11-10",{"date":334,"type":21},"2026-01-01",{"date":167,"type":21},{"name":337,"class":48},"University of Kansas Medical Center",{"id":339,"slug":340,"hasResults":11,"nctId":341,"briefTitle":342,"officialTitle":343,"acronym":4,"eligibilityCriteria":344,"healthyVolunteers":11,"sex":16,"minAge":176,"maxAge":345,"enrollmentInfo":346,"targetDuration":4,"studyType":22,"phases":347,"briefSummary":348,"conditions":349,"keywords":350,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":355,"lastUpdatePostDateStruct":356,"startDateStruct":358,"completionDateStruct":360,"leadSponsor":362,"locationsCount":49},"100603629","combined-effect-of-sensory-training-with-bobath-therapy-in-patients-with-chronic-stroke-100603629","NCT07139002","Combined Effect of Sensory Training With Bobath Therapy in Patients With Chronic Stroke","Combined Effect of Sensory Training With Bobath Therapy on Proprioception, Balance, and Motor Function in Patients With Chronic Stroke","Inclusion Criteria:\n\n* Both male and female included.\n* Age group: 45 years to 60 years.\n* Participants diagnosed with chronic stroke 6 months to 2 years.\n* Mini-Mental State Examination (MMSE) score of 24 or higher.\n* Cannot maintain balance for 30 seconds.\n* Ambulate independently for 7 meters.\n\nExclusion Criteria:\n\n* Participants having conditions other than chronic stroke (Parkinson's disease, Alzheimer's disease, orthopedic pathological condition, etc.).\n* Participants having any visual, vestibular, or auditory impairment.\n* Participants having any muscular injuries in the previous 6 months.\n* Participants with a history of fracture in the previous 6 months.\n* Participants with a history of mental illness.\n* Participants with cardiovascular complications.","60 Years",{"count":179,"type":21},[24],"Chronic stroke causes moderate to severe impairments in proprioception, balance, and motor functions, which can impact upon an individual's ability to perform activities of daily living, leading to reduced quality of life and increased dependency. Proprioception, or detecting the body's position in open space, is important for balance and coordinated movement. One therapy uses traditional rehabilitation methods like Bobath theory to increase motor functions, aiming to utilize sensory and movement facilitation. Nonetheless, combining sensory and Bobath therapy could lead to superior outcomes by simultaneously addressing both the proprioceptive deficit and motor skills. The purpose of this project is to explore the combined effect of sensory training and Bobath therapy on proprioception, balance, andmotor function in chronic stroke survivors.",[28],[351,352,71,306,353,354],"Bobath Therapy","Sensory training","Motor function","Proprioception","2025-08-18",{"date":357,"type":41},"2025-08-24",{"date":359,"type":41},"2025-01-01",{"date":361,"type":21},"2025-11-30",{"name":255,"class":48},{"id":364,"slug":365,"hasResults":11,"nctId":366,"briefTitle":367,"officialTitle":368,"acronym":4,"eligibilityCriteria":369,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":370,"enrollmentInfo":371,"targetDuration":4,"studyType":22,"phases":372,"briefSummary":373,"conditions":374,"keywords":375,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":380,"lastUpdatePostDateStruct":381,"startDateStruct":383,"completionDateStruct":385,"leadSponsor":387,"locationsCount":49},"100596184","wearable-device-and-behavioral-support-for-enhancing-arm-use-after-stroke-100596184","NCT07042152","Wearable Device and Behavioral Support for Enhancing Arm Use After Stroke","Sensor Enhanced Activity Motivation After Stroke","Inclusion Criteria:\n\n* 18 to 85 years of age\n* Experienced a single or multiple, ischemic or hemorrhagic stroke, with unilateral weakness, over six months previously\n* An ability to score at least 3 blocks on the Box and Block Test. BBT score of the affected arm is at least 5% worse than that present with the unaffected arm.\n* Absence of major depression, as defined by DSM V criteria or a score on the Geriatric Depression Scale \\\u003C 10.\n\nExclusion Criteria:\n\n* Any substantial decrease in alertness, language reception, or attention\n* Single or multiple, ischemic or hemorrhagic stroke less than 6 months ago\n* Severe muscle tone at the upper extremity (score ≥ 3 on the Modified Ashworth Spasticity scale)\n* Pregnant or lactating\n* Advanced liver, kidney, cardiac, or pulmonary disease\n* Coexistent major neurological disease\n* Coexistent major psychiatric disease\n* Plans to alter any current participation in other rehabilitation therapy in the time period of the study\n* A terminal medical diagnosis consistent with survival \\\u003C 1 year\n* A history of significant alcohol or drug abuse in the prior 3 years\n* Current enrollment in another study related to stroke or stroke recovery\n* Any other medical contraindication to participation in the study, as evaluated by our team physician.\n* Visual Analog of Pain Scale Score of 7 or greater","84 Years",{"count":241,"type":21},[24],"The goal of this study is to determine the effectiveness of behavioral support and feedback from a wearable device that senses arm movement in improving upper extremity function in a pilot, randomized controlled trial with chronic stroke patients",[28],[376,377,378,208,379],"Sensor","SmartWatch","Stroke Recovery","Motivational Interviewing","2025-08-14",{"date":382,"type":41},"2025-08-19",{"date":384,"type":21},"2025-08-20",{"date":386,"type":21},"2026-01-29",{"name":388,"class":48},"University of California, Irvine",{"id":390,"slug":391,"hasResults":11,"nctId":392,"briefTitle":393,"officialTitle":394,"acronym":4,"eligibilityCriteria":395,"healthyVolunteers":11,"sex":16,"minAge":396,"maxAge":397,"enrollmentInfo":398,"targetDuration":4,"studyType":399,"phases":4,"briefSummary":400,"conditions":401,"keywords":402,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":405,"lastUpdatePostDateStruct":406,"startDateStruct":408,"completionDateStruct":410,"leadSponsor":412,"locationsCount":4},"100599008","cognitive-impairment-and-gait-balance-in-chronic-stroke-survivors-100599008","NCT07078903","Cognitive Impairment and Gait Balance in Chronic Stroke Survivors","Relationship Between Cognitive Impairment and Gait Balance in Chronic Stroke Survivors: A Cross-Sectional Study","Inclusion Criteria:\n\n* Adults aged 25-75 years\n* Diagnosed with chronic stroke (≥6 months post-stroke)\n* Able to stand independently for testing\n* Capable of completing assessments or has an informant available for IQCODE\n\nExclusion Criteria:\n\n* Severe visual, vestibular, or musculoskeletal impairments\n* History of other neurological disorders\n* Acute illness or uncontrolled medical condition\n* Inability to follow instructions or complete cognitive\u002Fbalance assessments","25 Years","75 Years",{"count":96,"type":21},"OBSERVATIONAL","This study aims to investigate the relationship between cognitive impairment and gait balance in individuals with chronic stroke. Using the IQCODE and a balance assessment system, the study evaluates how post-stroke cognitive decline may influence stability and motor control. The findings will support better rehabilitation strategies tailored to cognitive function.",[28],[403,71,404],"Cognitive Impairment","Gait Balance","2025-07-14",{"date":407,"type":41},"2025-07-22",{"date":409,"type":21},"2025-08",{"date":411,"type":21},"2025-09",{"name":413,"class":48},"Islam Hassan Fayed",{"id":415,"slug":416,"hasResults":11,"nctId":417,"briefTitle":418,"officialTitle":419,"acronym":4,"eligibilityCriteria":420,"healthyVolunteers":11,"sex":16,"minAge":421,"maxAge":4,"enrollmentInfo":422,"targetDuration":4,"studyType":22,"phases":424,"briefSummary":425,"conditions":426,"keywords":4,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":428,"lastUpdatePostDateStruct":429,"startDateStruct":431,"completionDateStruct":433,"leadSponsor":435,"locationsCount":49},"100590979","effects-of-blood-flow-restriction-training-on-muscle-strength-and-physical-function-for-stroke-related-sarcopenia-100590979","NCT06974461","Effects of Blood Flow Restriction Training on Muscle Strength and Physical Function for Stroke-Related Sarcopenia","Effects of Blood Flow Restriction Training on Muscle Strength and Physical Function in Individuals With Stroke-Related Sarcopenia: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosed with chronic stroke (≥6 months post-stroke)\n* Diagnosed with sarcopenia, based on AWGS 2019 criteria\n\nExclusion Criteria:\n\n* Stroke occurred within the past 6 months\n* Resting systolic blood pressure \\> 200 mmHg\n* Resting diastolic blood pressure \\> 100 mmHg\n* Presence of implanted electronic or metallic devices that interfere with blood flow restriction cuffs\n* Contraindication to bioelectrical impedance analysis (e.g., pacemaker, ICD)","50 Years",{"count":423,"type":21},64,[24],"Effects of Blood Flow Restriction Walking on Muscle Strength and Physical Function in Chronic Stroke Patients with Sarcopenia: A Randomized, Sham-Controlled Trial Primary Objective: To evaluate the effects of BFR walking on muscle strength and physical function in chronic stroke patients with sarcopenia, compared to sham-BFR walking.\n\nSecondary Objective: (1) To explore the potential impact of BFR walking on muscle mass and vascular function in chronic stroke patients with sarcopenia. (2) To assess the influence of BFR walking on quality of life in chronic stroke patients with sarcopenia.",[427,28],"Sarcopenia","2025-05-07",{"date":430,"type":41},"2025-05-16",{"date":432,"type":21},"2025-05-15",{"date":434,"type":21},"2027-12-28",{"name":436,"class":48},"The Hong Kong Polytechnic University",{"id":438,"slug":439,"hasResults":11,"nctId":440,"briefTitle":441,"officialTitle":442,"acronym":4,"eligibilityCriteria":443,"healthyVolunteers":11,"sex":16,"minAge":444,"maxAge":397,"enrollmentInfo":445,"targetDuration":4,"studyType":22,"phases":446,"briefSummary":447,"conditions":448,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":449,"lastUpdatePostDateStruct":450,"startDateStruct":452,"completionDateStruct":454,"leadSponsor":456,"locationsCount":49},"100569641","mobile-applications-for-exercise-adherence-and-hand-function-in-chronic-stroke-100569641","NCT06696885","Mobile Applications for Exercise Adherence and Hand Function in Chronic Stroke.","Combined Effects of Mobile Based Video Games and Face to Face Exercise Program on Exercise Adherence and Hand Function in Chronic Stroke.","Inclusion Criteria:\n\n* Male and female patients age 30 to 75 years were included.\n* Chronic stroke patients ranging from 6 months to 2 years (41).\n* Participants having a stroke severity score \\> 6 on National Institute of Health Stroke Scale (NIHSS) (42).\n* Modified Ashworth scale score ≤ 3 of the affected upper extremity (44).\n* Montreal Cognitive Assessment (MoCA) score ≥ 26 (45).\n* Patients who are able to sit without support.\n* No contractures of the affected wrist and fingers.\n\nExclusion Criteria:\n\n* Participants who show the symptoms of global or receptive aphasia.\n* Participants who have medical problems or co-morbidities that interdict their participation in the study (such as shoulder pain in the paretic limb).\n* Patients with severe apraxia, somatosensory problems.\n* Severe spasticity of the affected wrist and finger flexors.","35 Years",{"count":241,"type":21},[24],"Stroke is a clinically defined syndrome characterized by an acute, focal neurological deficit due to vascular damage in the central nervous system. It is the second leading cause of death and disability globally. Stroke is not a singular disease but results from a variety of risk factors, disease processes, and mechanisms. Following a stroke, upper limb (UL) dysfunction affects 40-50% of individuals in the chronic phase, significantly impacting their ability to perform daily tasks. The latest trend in therapy involves the use of mobile video games within rehabilitation programs. These applications leverage the multi-touch interface of mobile devices to provide accurate monitoring of a patient's health status. Many of these mobile games are specifically designed to offer therapeutic tools that enhance dexterity and improve adherence to exercise routines.",[28],"2024-11-18",{"date":451,"type":41},"2024-11-20",{"date":453,"type":41},"2023-01-12",{"date":455,"type":21},"2024-11",{"name":255,"class":48},{"id":458,"slug":459,"hasResults":11,"nctId":460,"briefTitle":461,"officialTitle":461,"acronym":462,"eligibilityCriteria":463,"healthyVolunteers":11,"sex":16,"minAge":176,"maxAge":177,"enrollmentInfo":464,"targetDuration":4,"studyType":22,"phases":466,"briefSummary":467,"conditions":468,"keywords":469,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":449,"lastUpdatePostDateStruct":473,"startDateStruct":475,"completionDateStruct":476,"leadSponsor":478,"locationsCount":49},"100569756","the-effect-of-mirror-therapy-on-upper-extremity-motor-function-in-stroke-rehabilitation-100569756","NCT06698380","The Effect of Mirror Therapy on Upper Extremity Motor Function in Stroke Rehabilitation","MT","Inclusion Criteria:\n\n* Duration of stroke more than six months\n* Subjects of chronic stroke with left or right hemiplegia.\n* Genders of male and female with age ranging between forty-five to sixty-five years.\n* MMSE scores greater than 23 out of 30.\n* Scored one or one plus on MAS on all muscles of the affected upper limb.\n* Have normal visual perception.\n* Able to follow oral commands.\n\nExclusion Criteria:\n\n* Unable to follow visual and oral commands.\n* Unilateral neglect.\n* Cognitive impairments (MMSE scores less than 24 out of 30), or language deficits.\n* Any other neurological disorders and recent surgeries.\n* Previous exposure to MT.",{"count":465,"type":21},38,[24],"The study aimed to determine the effect of mirror therapy versus conventional physical therapy treatment in improving upper extremity impairments and motor function among chronic hemiplegic subjects.\n\nResearch Objectives:\n\n1. To discover the effectiveness of conventional physical therapy treatment on improving upper limb motor function among chronic hemiplegic subjects.\n2. To find out the effect of mirror therapy along with conventional physical therapy treatment on improving upper limb motor function among chronic hemiplegic subjects.\n3. To find out the effectiveness of mirror therapy combined with conventional physical therapy treatment versus conventional physical therapy treatment alone on improving upper extremity motor function among chronic hemiplegic subjects.",[27,28,270],[470,270,471,33,472],"storke","mirror therapy","motor function",{"date":474,"type":41},"2024-11-21",{"date":449,"type":41},{"date":477,"type":21},"2025-07-30",{"name":479,"class":480},"University of Jazan","OTHER_GOV",{"id":482,"slug":483,"hasResults":11,"nctId":484,"briefTitle":485,"officialTitle":485,"acronym":486,"eligibilityCriteria":487,"healthyVolunteers":11,"sex":16,"minAge":176,"maxAge":177,"enrollmentInfo":488,"targetDuration":4,"studyType":22,"phases":490,"briefSummary":491,"conditions":492,"keywords":493,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":499,"lastUpdatePostDateStruct":500,"startDateStruct":501,"completionDateStruct":503,"leadSponsor":505,"locationsCount":49},"100569309","the-effect-of-modified-constraint-induced-movement-therapy-on-upper-extremity-function-in-stroke-rehabilitation-100569309","NCT06692569","The Effect of Modified Constraint Induced Movement Therapy on Upper Extremity Function in Stroke Rehabilitation","mCIMT","Inclusion Criteria:\n\n* Right or left-sided chronic hemiplegic patients.\n* Onset of stroke More than six months.\n* Age between 45 to 65 years of both genders.\n* Mini-Mental State Examination - Scored more than 24\u002F30.\n* Modified Ashworth Scale for spasticity 1 or 1+.\n* Have at least 20° wrist active extension and at least 10° of metacarpophalangeal active extension of the paretic upper extremity.\n* Have at least grade 2\u002F5 of muscle power on upper extremity especially in wrist extensors.\n* Have normal visual perception.\n* With no other neurological disorders.\n\nExclusion Criteria:\n\n* Unable to follow visual and oral commands.\n* Unilateral neglect.\n* Severe cognitive, or language deficits.",{"count":489,"type":21},34,[24],"The purpose of the study is to determine the effect of Modified Constraint-Induced Movement Therapy and trunk restraint contrasted with conventional physical therapy treatment on improving upper extremity function, balance, and quality of life among chronic hemiplegic patients.\n\n* To find out the effectiveness of conventional physical therapy treatment on improving upper extremity function, balance, and quality of life among chronic hemiplegic patients.\n* To find out the effectiveness of modified constraint induced movement therapy (mCIMT) and trunk restraint along with conventional physical therapy treatment on improving upper extremity function, balance, and quality of life among chronic hemiplegic patients.\n* To find out the effectiveness of modified constraint induced movement therapy (mCIMT) and trunk restraint combined with conventional physical therapy treatment versus conventional physical therapy treatment alone on improving upper extremity function, balance, and quality of life among chronic hemiplegic patients.",[27,270,28],[106,494,495,496,497,498],"hemiplegia","constraint induced movement therapy","modified constraint induced movement therapy","trunk restrain","upper extremity motor function","2024-11-14",{"date":449,"type":41},{"date":502,"type":41},"2024-11-12",{"date":504,"type":21},"2025-07-13",{"name":479,"class":480},{"id":507,"slug":508,"hasResults":11,"nctId":509,"briefTitle":510,"officialTitle":511,"acronym":512,"eligibilityCriteria":513,"healthyVolunteers":11,"sex":16,"minAge":176,"maxAge":177,"enrollmentInfo":514,"targetDuration":4,"studyType":22,"phases":515,"briefSummary":516,"conditions":517,"keywords":518,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":502,"lastUpdatePostDateStruct":521,"startDateStruct":523,"completionDateStruct":525,"leadSponsor":527,"locationsCount":49},"100569117","the-effect-of-motor-relearning-program-on-functional-mobility-in-stroke-rehabilitation-100569117","NCT06690073","The Effect of Motor Relearning Program on Functional Mobility in Stroke Rehabilitation.","The Effect of Motor Relearning Program on Functional Mobility in Stroke Rehabilitation","MRP","Inclusion criteria: The following subjects were included:\n\n* Right or left-sided chronic hemiplegic subjects.\n* More than six months after the onset of stroke.\n* Age group between 45-65 years of both genders.\n* Scored minimally 24\u002F30 on the Mini-Mental State Exam (MMSE).\n* Motor assessment scale of sitting to standing section.\n* Having normal visual perception.\n* Able to follow verbal commands.\n\nExclusion criteria: The following subjects were excluded:\n\n* Less than six months after the onset of stroke.\n* Unable to follow visual and oral commands.\n* The age group is below 45 years and more than 65 years.\n* Unilateral neglect.\n* Cognitive impairments (MMSE scores less than 24\u002F30), or language deficits.\n* Any other neurological disorders and recent surgeries.\n* Previous exposure to MRP.",{"count":241,"type":21},[24],"1. To find out the effectiveness of conventional physiotherapy on improving functional mobility of lower extremity among chronic hemiplegic subjects.\n2. To find out the effcctiveness of motor relearning program along with conventional physical therapy treatment on improving functional mobility of lower extremity among chronic hemiplegic subjects.\n3. To find out the effectiveness of motor relearning program along with conventional physical therapy treatment over conventional physical therapy on improving functional mobility of lower extremity among chronic hemiplegic subjects.",[27,28,104,270],[27,270,519,520],"Functional mobility","motor relearning program",{"date":522,"type":41},"2024-11-15",{"date":524,"type":41},"2024-11-04",{"date":526,"type":21},"2025-06-30",{"name":479,"class":480}]