[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"chronic-subdural-hematomas\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:chronic-subdural-hematomas":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,49,75,100,126,151,178,199],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":26,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":4},"100639853","prospective-mma-embolization-registry-100639853",false,"NCT07626671","Prospective MMA Embolization Registry","Prospective Outcomes of MMA Embolization: A Prospective Single-center Registry Investigating Endovascular Therapy for Chronic Subdural Hematomas","PRO-EMMA","Inclusion Criteria:\n\n* CT- or MRI-confirmed chronic subdural hematoma (cSDH)\n* Planned or completed middle meningeal artery embolization (MMAE), either as primary treatment or as adjunct to surgical evacuation\n* Age ≥ 18 years\n* Modified Rankin Scale (mRS) ≤ 3 at baseline\n* Written informed consent including agreement to structured follow-up (follow-up CT scans and clinical assessments)\n* Willingness and ability to participate in structured follow-up assessments (telephone and\u002For in-person interviews)\n\nExclusion Criteria:\n\n* Acute subdural hematoma requiring emergency neurosurgical intervention\n* Missing or incomplete baseline clinical or radiological data\n* Unavailability for prospective follow-up (e.g., no fixed address, no telephone contact)","ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","OBSERVATIONAL","Chronic subdural hematoma (cSDH) is a common condition, particularly in older adults, that can substantially impair patients' quality of life, functional independence, and neurological well-being. Blood accumulates in the subdural space and persists due to the formation of a highly vascularized outer hematoma membrane. This membrane continuously rebleeds through fragile neovessels, driven in large part by branches of the middle meningeal artery (MMA), preventing spontaneous resolution and promoting hematoma growth. The standard treatment is surgical drainage, but recurrence rates reach up to 30%, largely because surgery does not address the underlying membrane vascularity. Middle meningeal artery embolization (MMAE) is a minimally invasive angiographic procedure that targets this root cause by occluding the arterial supply to the hematoma membrane, thereby reducing rebleeding and promoting resolution. Recent clinical trials and meta-analyses have demonstrated high efficacy and safety of MMAE, both as a standalone treatment and as an adjunct to surgery. Despite this evidence, standardized prospective data on patient selection, predictors of treatment success, and optimal follow-up are still lacking.\n\nPRO-EMMA is a prospective, single-center registry at the Charité - Universitätsmedizin Berlin, a tertiary center consisting of three separate campuses. Pro-Emma systematically collects clinical, radiological, and procedural data from patients with cSDH who undergo MMAE. In addition to routine clinical care, participants undergo a structured follow-up protocol: CT scans within 7 days and at 3 months after the procedure, and standardized assessments of neurological status, functional outcome, and quality of life - using the Glasgow Coma Scale (GCS), Markwalder score, modified Rankin Scale (mRS), Glasgow Outcome Scale Extended (GOS-E), and EQ-5D-5L- before the procedure and at days 30, 90, and 120 post-intervention.\n\nThe study tests the hypothesis that MMAE leads to good functional outcomes, rapid hematoma resolution, and low recurrence rates, and that specific clinical, interventional, and imaging features predict treatment success. Findings will help identify which patients benefit most from MMAE, optimize treatment decisions, and establish a practical, evidence-based follow-up standard. The registry aims to enroll 75-150 patients over approximately 12 months.",[25],"Chronic Subdural Hematomas",[27,28,29,30,31,32,33,34,35,36],"chronic subdural hematoma","Middle meningeal artery embolization","MMAE","cSDH","Endovascular treatment","Hematoma recurrence","Modified Rankin Scale","Functional outcome","Neuroradiology","Prospective registry","NOT_YET_RECRUITING","2026-05-31",{"date":40,"type":41},"2026-06-04","ACTUAL",{"date":43,"type":21},"2026-07-01",{"date":45,"type":21},"2028-01-31",{"name":47,"class":48},"Charite University, Berlin, Germany","OTHER",{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":4},"100641048","phil-middle-meningeal-artery-embolization-for-first-line-treatment-of-chronic-subdural-hematoma-ide-trial-100641048","NCT07576998","PHIL™ Middle Meningeal Artery Embolization for First-Line Treatment of Chronic Subdural Hematoma IDE Trial","PHIL™ (Precipitating Hydrophobic Injectable Liquid) Middle Meningeal Artery Embolization (MMAE) for First-Line Treatment of Chronic Subdural Hematoma (cSDH) IDE Trial (PHILFIRST)","PHILFIRST","Inclusion Criteria:\n\n* Age 22 years or older\n* Diagnosis of chronic subdural hematoma\n* Subject, or their legally authorized representative provides a signed and dated Informed Consent Form\n* Pre-morbid mRS 0-1\n* cSDH measures ≥ 10 mm in greatest thickness\n* cSDH exerts mass effect upon the subjacent brain\n* Imaging characteristics indicative of chronicity\n* Negative urine pregnancy test for female subjects of child-bearing potential\n* Subject is able and willing to comply with all study protocol requirements, including return to the investigational site for all follow-up visits\n* Subject presents with one or more of the following neurological symptoms: headache\u002Fhead pressure, cognitive decline, speech difficulty or aphasia, gait impairment or imbalance, focal neurological deficit (weakness, paresthesia or sensory deficit involving of one or more extremities or facial droop), and\u002For seizure\n\nExclusion Criteria:\n\n* Prior ipsilateral craniotomy or burr hole evacuation of cSDH\n* Prior embolization of either MMA\n* Requires (in the opinion of the treating surgeon) full or mini-craniotomy at time of randomization\n* Emergent subdural hematoma evacuation needed\n* cSDH with a focal location\n* cSDH developed due to underlying condition\n* Life expectancy of \\\u003C1 year\n* Presents with an intracranial mass other than subdural hematoma\n* Presents with a meningioma with mass effect and\u002For ≥1 cm or currently undergoing radiation therapy for carcinoma or sarcoma of the head or neck region\n* Serum creatinine level \\> 3.0 mg\u002FdL at time of enrollment and not on dialysis\n* Life-threatening allergy to radiographic contrast (unless treatment for allergy is tolerated or can be managed medically)\n* Currently enrolled in another investigational study protocol that could potentially confound the interpretation of the study endpoints\u002Foutcomes\n* Known dangerous anatomic variations leading to increased procedural risk or unsafe access for MMAE\n* Contraindicated for the use of PHIL™ liquid embolic system","22 Years",{"count":59,"type":21},475,"INTERVENTIONAL",[62],"NA","This is a prospective, randomized, controlled, open-label, blinded endpoint (PROBE) clinical investigation in which patients with non-emergent chronic subdural hematoma (cSDH) requiring treatment will be randomized (1:1) to either initial surgical evacuation (Control Arm) or initial MMAE with PHIL™ (investigational arm).",[25],"2026-05-04",{"date":67,"type":41},"2026-05-08",{"date":69,"type":21},"2026-12-31",{"date":71,"type":21},"2031-05-31",{"name":73,"class":74},"Microvention-Terumo, Inc.","INDUSTRY",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":60,"phases":84,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":99},"100635769","phase-2-prospective-clinical-investigation-on-infection-as-a-cause-of-chronic-subdural-hematoma-100635769","NCT07556991","Prospective Clinical Investigation on Infection as a Cause of Chronic Subdural Hematoma.","iSDH","Inclusion Criteria:\n\n* \\>18 years of age\n* surgical treatment of chronic subdural hematoma\n\nExclusion Criteria:\n\n* prior or current antibiotic treatment\n* infection\n* recurrent chronic subdural hematoma\n* conservatively treated chronic subdural hematoma",{"count":83,"type":21},164,[85,86],"PHASE2","PHASE3","Chronic subdural hematoma (cSDH) is a very common disease, primarily affecting older people, and is associated with significant morbidity and mortality. The incidence described in the literature is approximately 5 per 100,000\u002Fyear, but it occurs more frequently in the elderly, with up to 58 per 100,000\u002Fyear. The recurrence rate is high and is described in the literature as 10 to 27%. Consequently, various studies have evaluated potential risk factors for hematoma recurrence, such as age, brain atrophy, mixed HU density in CCT, increased body mass index, and bilateral hematomas. The pathomechanism of recurrence is currently unknown.\n\nThe mechanism of development after minor trauma and the progression of the hematoma to a symptomatic form remain unclear. A recent retrospective investigation submitted for publication by the applicant, regarding the occurrence of a low-grade infection in patients with recurrent hematomas, examined this as a possible cause. In this study, microbiological swabs were taken from the subdural space after hematoma evacuation. It was shown that a low-grade infection could be detected in approximately 30% of all hematoma recurrences. This is previously unknown in the neurosurgical literature. This raises the question of whether a low-grade infection is already present in the primary chronic subdural hematoma.",[25],"RECRUITING","2026-04-22",{"date":92,"type":41},"2026-04-29",{"date":94,"type":41},"2024-09-01",{"date":96,"type":21},"2027-06-30",{"name":98,"class":48},"University of Rostock",1,{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":60,"phases":110,"briefSummary":111,"conditions":112,"keywords":113,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":122,"leadSponsor":124,"locationsCount":4},"100635223","middle-meningeal-artery-coagulation-during-burr-hole-drainage-for-chronic-subdural-haematoma-burr-mma-100635223","NCT07549893","Middle Meningeal Artery Coagulation During Burr-Hole Drainage for Chronic Subdural Haematoma (BURR-MMA)","BURR-MMA: A Prospective Pilot Feasibility Study of Intra-operative Middle Meningeal Artery Coagulation During Burr-Hole Surgery for Chronic Subdural Haematoma","BURR-MMA","Inclusion Criteria:\n\n* Age ≥18 years.\n* Chronic or subacute subdural haematoma scheduled for burr-hole evacuation.\n* Treating surgeon considers the CT- and navigation-guided MMA adjunct technically feasible and safe to attempt, recognising that the adjunct may be abandoned intra-operatively according to protocol bail-out criteria.\n* Written informed consent, or consultee declaration under the Mental Capacity Act (MCA), with re-consent if capacity returns.\n\nConsented participants who meet eligibility criteria will be enrolled sequentially until the target sample size of 20-30 participants is reached. No randomisation is used in this feasibility phase.\n\nExclusion Criteria:\n\n* Acute subdural haematoma requiring craniotomy or decompressive surgery.\n* Prior ipsilateral MMA embolisation.\n* Clear contraindication to pre-operative CT\n* Inability to complete Day-90 follow-up.\n* Pregnancy or breastfeeding (due to radiation exposure from CT imaging as part of standard clinical care).\n\nIf CT is non-diagnostic or cannot be performed, participants will continue with standard burr-hole evacuation without the MMA adjunct; this does not constitute a protocol deviation.",{"count":109,"type":21},30,[62],"Chronic subdural haematoma (cSDH) is a common condition in older adults, usually treated by burr-hole surgery to drain the collection. Even with good surgery, around 1 in 10 patients develop a recurrence and need a second operation. Research shows that the outer lining of the haematoma is fed by small branches of the middle meningeal artery (MMA), and interrupting these branches may lower the risk of recurrence.\n\nThis study looks at whether surgeons can safely and reliably coagulate these small MMA branches at the same time as standard burr-hole drainage, using the routine pre-operative CT scan and surgical navigation already used in everyday practice. Adults (aged 18 years and over) scheduled for burr-hole drainage of a chronic or subacute subdural haematoma will be invited to take part. The procedure, recovery, drain management, and 90-day follow-up will otherwise follow standard NHS care.\n\nNo additional imaging is required for the study, and participants are not exposed to any extra radiation. The main purpose is feasibility and safety, not to prove effectiveness. Findings will inform the design of a future multicentre study.",[25],[114,115,116],"chronic subdural haematoma","middle meningeal artery","burrholes","2026-04-17",{"date":119,"type":41},"2026-04-24",{"date":121,"type":21},"2026-08-01",{"date":123,"type":21},"2027-12-01",{"name":125,"class":48},"University College, London",{"id":127,"slug":128,"hasResults":11,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":132,"eligibilityCriteria":133,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":134,"enrollmentInfo":135,"targetDuration":4,"studyType":60,"phases":137,"briefSummary":138,"conditions":139,"keywords":4,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":150},"100528651","middle-meningeal-artery-embolization-for-chronic-subdural-hematomas-stormm-100528651","NCT06163547","Middle Meningeal Artery Embolization for Chronic Subdural Hematomas (STORMM)","Middle Meningeal Artery (MMA) Embolization for cSDH: Rationale and Design for the STOp Recurrence of MMA Bleeding (STORMM) Randomized-Control Trial","STORMM","Inclusion Criteria:\n\n* Age: 18-100\n* Consent possible\n* cSDH located at the convexities\n* Patients with symptomatic cSDH\n* Patients with asymptomatic large chronic\u002Fsubacute hematoma after 6 weeks of failed conservative treatment\n\nExclusion Criteria:\n\n* Consent not possible\n* Pregnancy\n* Prisoner\n* Angiography contraindication\n* Patient for whom follow-up is problematic (e.g. distant residency, homeless …)\n* Previous surgery for cSDH","100 Years",{"count":136,"type":21},180,[62],"Chronic Subdural Hematomas (cSHD) are common, and due to cerebral compression, often result in neurological impairment and reduced consciousness. Surgery is typically performed once neurological symptoms develop. Recent studies suggest that arteries nourished by the middle meningeal artery (MMA) may be responsible for hematoma progression and that MMA embolization is clinically useful. There is less evidence, that embolization of MMA also may be a treatment option for individuals without surgical treatment. The investigators propose a multicentre study to investigate both potentials: (1) Assessment of efficacy of embolization after surgery to reduce recurrence and improve outcomes by conducting a randomized trial (randomization arms; Arms 1 and 2), (2) Assessment of embolization-alone efficacy when surgery is contraindicated or refused (embolization-only arm, Arms 3 and 4).",[25,140],"Cerebral Compression Due to Injury","2026-03-16",{"date":143,"type":41},"2026-03-17",{"date":145,"type":41},"2025-02-18",{"date":147,"type":21},"2027-01-01",{"name":149,"class":48},"University Hospital, Geneva",2,{"id":152,"slug":153,"hasResults":11,"nctId":154,"briefTitle":155,"officialTitle":156,"acronym":157,"eligibilityCriteria":158,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":159,"targetDuration":161,"studyType":22,"phases":4,"briefSummary":162,"conditions":163,"keywords":165,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":169,"lastUpdatePostDateStruct":170,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":99},"100625347","implementation-of-an-enhanced-recovery-pathway-for-burr-hole-drainage-in-patients-with-a-chronic-subdural-hematoma-100625347","NCT07421453","Implementation of an Enhanced Recovery Pathway for Burr-hole Drainage in Patients With a Chronic Subdural Hematoma","Enhanced Recovery Pathway for Chronic Subdural Hematoma","ERP-cSDH","Inclusion Criteria:\n\n* Age 18 years or older\n* Existence of a chronic subdural hematoma requiring burr-hole drainage\n* Written informed consent to participate in the study must be obtained from the subject. If the subject is not capable of self-consent, all efforts will be made to locate a legally acceptable representative to act on behalf of the subject. When the patient is considered capable to consent but physically unable to sign an informed consent form and a representative is not available an impartial witness can attend the informed consent process.\n\nExclusion Criteria:\n\n* Existence of an important underlying cerebral lesion (e.g. a vascular lesion, tumor)\n* History of treatment (surgical or by middle meningeal artery embolization) of a same sided cSDH",{"count":160,"type":21},150,"6 Months","A chronic subdural hematoma (cSDH) is a type of intracranial hematoma that primarily affects older adults. The rising incidence of this condition, coupled with the high healthcare burden of this disease, calls for an update of the medical care program. We introduced an enhanced recovery protocol (ERP) at our center for patients undergoing surgical treatment (by means of burr-hole drainage) for a cSDH. Our ERP includes guidelines for treatment decisions (surgery or middle meningeal artery embolization), modifications in surgical techniques, and standardized postoperative management strategies. This study prospectively analyses the safety and efficacy of this enhanced recovery protocol for patients undergoing burr hole drainage of a chronic subdural hematoma. Safety and efficacy outcomes will be compared with outcomes of a historical patient cohort. Safety of the protocol will be measured in terms of recurrence rate (6-month follow-up, primary outcome), complication incidence, and 30-day mortality. Efficacy of the enhanced recovery protocol will be represented by the length-of-stay.",[164,25],"Chronic Subdural Hematoma",[166,167,168],"Chronic subdural hematoma","Burr-hole drainage","Enhanced recovery protocol","2026-02-16",{"date":171,"type":41},"2026-02-19",{"date":173,"type":41},"2024-12-23",{"date":175,"type":21},"2028-07-31",{"name":177,"class":48},"Universitaire Ziekenhuizen KU Leuven",{"id":179,"slug":180,"hasResults":11,"nctId":181,"briefTitle":182,"officialTitle":183,"acronym":184,"eligibilityCriteria":185,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":186,"targetDuration":161,"studyType":22,"phases":4,"briefSummary":188,"conditions":189,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":191,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":197,"locationsCount":150},"100609441","prospective-multi-center-single-arm-study-for-subjects-with-chronic-subdural-hematoma-treated-with-i-ed-coils-either-alone-or-in-combination-with-burr-holes-or-mini-craniotomy-100609441","NCT07214623","Prospective Multi-center Single Arm Study for Subjects With Chronic Subdural Hematoma Treated With i-ED COILs, Either Alone or in Combination With Burr-holes or Mini-craniotomy","i-ED COIL Use for Reduction of Chronic Subdural Hematoma Post Market Study","iCURE cSDH","Inclusion Criteria:\n\n* Pre morbid mRS 0-3\n* Chronic subdural symptomatic, requiring intervention\n\nExclusion Criteria:\n\n* Acute subdural hematoma\n* Intercranial mass other than subdural hematoma\n* Females pregnant or breast feeding\n* Compromised survival or inability to complete trial",{"count":187,"type":21},200,"All participants will be asked to have a minimally invasive procedure for the treatment of chronic subdural hematoma, a blood clot on the brain. Depending on the specific condition patients may also have a surgical procedure, a mini-craniotomy or burr holes where the skull is pierced and the blood clot is drained.",[164,30,25],"2025-10-02",{"date":192,"type":41},"2025-10-09",{"date":194,"type":21},"2025-11-30",{"date":196,"type":21},"2027-05-31",{"name":198,"class":74},"Kaneka Medical America LLC",{"id":200,"slug":201,"hasResults":11,"nctId":202,"briefTitle":203,"officialTitle":204,"acronym":205,"eligibilityCriteria":206,"healthyVolunteers":11,"sex":17,"minAge":207,"maxAge":208,"enrollmentInfo":209,"targetDuration":4,"studyType":60,"phases":211,"briefSummary":212,"conditions":213,"keywords":4,"overallStatus":89,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":99},"100401770","embolization-of-middle-meningeal-artery-in-chronic-subdural-hematoma-100401770","NCT04511572","Embolization of Middle Meningeal Artery in Chronic Subdural Hematoma","Improving the Outcome of Chronic Subdural Hematoma by Embolization of Middle Meningeal Artery (ELIMINATE)","ELIMINATE","Inclusion Criteria:\n\n* · CT-confirmed diagnosis of chronic Subdural Hematoma;\n\n  * Primary surgical treatment based on clinical symptoms (progressive neurological deficits).\n\nExclusion Criteria:\n\n* · Significant contraindication to angiography (eg. allergy for contrast);\n\n  * Structural causes for subdural hemorrhage, e.g. arachnoid cysts, cortical vascular malformations and a history of cranial surgery in the previous 365 days;\n  * Inability to obtain informed consent from the patient or legal representative (when the patient has a depressed level of consciousness), including language barrier;\n  * Monocular blindness on contralateral side of the hematoma;","50 Years","90 Years",{"count":210,"type":21},170,[62],"Chronic subdural hematoma (cSDH) is a common neurological affliction which affects mostly frail and elderly patients. Surgical evacuation by using burr hole craniostomy (BHC) is the most frequently used treatment but carries a recurrence rate varying between 10-30% in the literature. Especially in this frail population re-operation is undesirable. Embolization of the middle meningeal artery is an adjuvant treatment which has been reported in multiple case reports and larger case series, showing a beneficial effect on recurrence rate, reducing it to \\\u003C5%, without complications.\n\nObjectives: Primary: To evaluate whether additional embolization of the middle meningeal artery after surgery for cSDH reduces the recurrent surgery rate. Secondary: to evaluate whether the use of middle meningeal artery embolization after surgical treatment in symptomatic cSDH patients increases quality of life (SF-36 and the EQ-5D-5L), performance in activities of daily living (AMC Linear Disability Score), functional outcome (mRS), cognitive functioning (MOCA) and reduces mortality, occurrence of complications, recurrence rate, size and volume of the hematoma, neurological impairment (mNIHSS, Markwalder score) and the use of care and health-related costs (iMCQ and iPCQ).\n\nStudy design: Multicenter, randomized controlled open-label superiority trial. Study population: Patients diagnosed with a cSDH who require surgery. Intervention: The intervention group will receive embolization in addition to standard surgical treatment. The control group will receive surgery only.\n\nMain study endpoint: The number of patients who require reoperation within 24 weeks after the intervention.\n\nSymptomatic cSDH patients will undergo peri-operative embolization of the middle meningeal artery until 72 hours after surgical treatment. Complications are monitored during hospital admission and follow-up. Radiological and clinical follow-up is at eight, 16 and 24 weeks post-intervention with a CT-scan of the head and assessment of mRS, MOCA, mNIHSS, Markwalder score, SF-36, EQ-5D-5L, ALDS, iMCQ and iPCQ. Standard care after surgery entails outpatient follow-up with on average two CT-scans, indicated by clinical signs and symptoms.",[25],"2024-07-30",{"date":216,"type":41},"2024-07-31",{"date":218,"type":41},"2020-12-10",{"date":220,"type":21},"2025-10-01",{"name":222,"class":48},"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)"]