[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cigarette-addiction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cigarette-addiction":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100636358","impact-of-novel-vs-usual-brand-menthol-cigarettes-on-abuse-liability-100636358",false,"NCT07564648","Impact of Novel vs. Usual Brand Menthol Cigarettes on Abuse Liability","Inclusion Criteria:\n\n* Aged 21 years or older\n* Currently smoke cigarettes daily (≥ 5 cigarettes\u002Fday) for at least the past 6 months, and their usual brand is menthol cigarettes\n* Willing to provide informed consent\n* Willing to abstain from all nicotine, tobacco, and smoked cannabis products for approximately 12 hours prior to each study visit\n* Own and regularly use a functional smartphone compatible with study procedures (e.g., completing daily assessments)\n* Willing to complete two weeks of daily assessments involving use of their usual brand menthol cigarettes and the study product\n* Able to read, speak, and understand English\n\nExclusion Criteria:\n\n* Current diagnosis of any significant lung diseases (e.g., asthma, chronic obstructive pulmonary disease, cystic fibrosis)\n* History of a cardiac event or episode of cardiac distress (e.g., heart attack, hospitalization for chest pain) within the past 3 months\n* Currently pregnant, planning to become pregnant during the study period, or currently breastfeeding\n* Self-reported use of any non-cigarette nicotine or tobacco product (e.g., e-cigarettes, cigars, oral nicotine products) or cannabis on more than 10 days in the past 30 days\n* Self-reported current participation in a smoking cessation program or intention to quit smoking in the next 3 months\n* Self-reported difficulty with blood draws",true,"ALL","21 Years",{"count":19,"type":20},48,"ESTIMATED","INTERVENTIONAL",[23],"NA","This randomized, double-blind, crossover human laboratory study compares the abuse liability of cigarettes containing menthol and non-menthol cigarette variants, using the participant's usual brand menthol cigarette as a within-subject reference. Participants complete standardized laboratory smoking sessions, behavioral economic tasks, and a naturalistic observational period. The study examines differences in nicotine delivery, smoking behavior, and subjective effects across cigarette types in laboratory and real-world contexts.",[26,27],"Cigarette Addiction","Tobacco Use Disorder",[26,29],"Cigarette","NOT_YET_RECRUITING","2026-06-03",{"date":33,"type":34},"2026-06-05","ACTUAL",{"date":36,"type":20},"2026-06-22",{"date":38,"type":20},"2029-09-30",{"name":40,"class":41},"Ohio State University Comprehensive Cancer Center","OTHER"]