[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"class-i-malocclusion\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:class-i-malocclusion":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,50,75,107],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100628822","llllt-vs-piezocision-in-accelerating-orthodontic-canine-retraction-100628822",false,"NCT07466641","LLLLT vs Piezocision in Accelerating Orthodontic Canine Retraction","Effectiveness of Piezocision Versus Low-level Laser Therapy During Orthodontic Canine Retraction: A Comparative Controlled Clinical Study","Inclusion Criteria:\n\n* Age range 18-25 years.\n* Patients with crowding or protrusion requiring at least bilateral maxillary first premolar extraction followed by symmetrical canine retraction.\n* Full set of permanent dentition (third molar not considered).\n* Patients with good oral hygiene.\n\nExclusion Criteria:\n\n* Previous orthodontic treatment.\n* Patients taking medications or suffering from systemic conditions that can affect orthodontic tooth movement.\n* Active periodontal diseases and\u002For untreated carious lesions.\n* Congenital orofacial deformities.\n\nDiscontinuation criteria:\n\n* Multiple missing appointments.\n* Poor oral hygiene.\n* Multiple broken appliances to the extent that interferes with obtaining the treatment objectives.","ALL","18 Years","25 Years",{"count":20,"type":21},21,"ESTIMATED","INTERVENTIONAL",[24],"NA","This comparative controlled clinical study aims to evaluate and compare the effectiveness of piezocision and low-level laser therapy (LLLT) as adjunctive interventions to accelerate orthodontic canine retraction. Participants will be randomly assigned to one of three groups: piezocision, LLLT, or a control group (no adjunctive procedure). The study will assess the impact of these interventions on the rate of tooth movement, the type of tooth movement, and patient experience.",[27,28,29],"Malocclusion, Angle Class II, Division 1","Bimaxillary Protrusion","Class I Malocclusion",[31,32,33,34,35,36],"canine retraction","Low-level laser therapy","laser","piezocision","piezosurgery","orthodontic canine retraction","RECRUITING","2026-05-06",{"date":40,"type":41},"2026-05-11","ACTUAL",{"date":43,"type":41},"2026-04-01",{"date":45,"type":21},"2027-06",{"name":47,"class":48},"Hesham Nabil Ali Al-Qamhawy","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":49},"100633021","nano-coated-orthodontic-miniscrews-for-en-mass-retraction-of-the-upper-arch-100633021","NCT07521267","Nano Coated Orthodontic Miniscrews for en Mass Retraction of the Upper Arch","Evaluation of Silver-Hydroxyapatite Nano-coated Versus Uncoated Orthodontic Miniscrews for en Masse Retraction of the Upper Anterior Segment: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Class I orthodontic cases with bimaxillary protrusion of the anterior segment of the upper jaw that need at least extraction for orthodontic treatment.\n* Age 14-20 years.\n* Good oral hygiene with healthy periodontium.\n* Need for an absolute skeletal anchorage.\n* Systemically healthy patients.\n\nExclusion Criteria:\n\n* Patient with craniofacial anomalies (e.g, cleft lip and palate)\n* Presence of systemic diseases or syndromes affecting bone metabolism (e.g, osteoporosis, rickets)\n* Poor oral hygiene or uncooperative patients.\n* Extensive dental caries or untreated periodontal disease.\n* History of trauma or surgery affecting the maxilla or mandible.","14 Years","20 Years",{"count":60,"type":21},14,[24],"study will be directed to evaluate silver-hydroxyapatite nano-coated versus uncoated orthodontic miniscrews for en masse retraction of the upper anterior segment.",[29,64,65],"Maxillary Prognathism","Orthodontic Tooth Movement","2026-04-08",{"date":68,"type":41},"2026-04-13",{"date":70,"type":21},"2026-05",{"date":72,"type":21},"2029-11",{"name":74,"class":48},"Al-Azhar University",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":16,"minAge":83,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":86,"phases":4,"briefSummary":87,"conditions":88,"keywords":92,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":49},"100605456","assesment-of-ethnic-bias-in-an-artificial-intelligence-based-orthodontic-diagnosis-system-100605456","NCT07162753","Assesment of Ethnic Bias in an Artificial Intelligence Based Orthodontic Diagnosis System","Detection of Racial Bias in an Artificial Intelligence Based Orthodontic Diagnosis System","* Patients with lateral profile photographs taken before starting orthodontic treatment\n* Profile photographs with a plain background\n* Patient in natural head position facing forward\n* No beard or mustache that could camouflage the profile\n* Availability of lateral cephalometric radiographs taken before treatment together with the profile photograph\n\nExclusion criteria:\n\n* Blurry missing or non standard profile photographs\n* Presence of beard mustache scars cleft lip palate or soft tissue deformities that may significantly affect facial appearance\n* Previous orthodontic treatment history",true,"4 Years",{"count":85,"type":21},5000,"OBSERVATIONAL","This study explores how artificial intelligence (AI) can be used in orthodontics, which is the area of dentistry that focuses on correcting jaw and bite problems. AI is a computer technology that can learn from large amounts of data and then make predictions or decisions. It is already being tested in medicine and dentistry to help doctors and dentists diagnose conditions.\n\nFor this study, the AI system was trained using photographs and X-rays from patients in Turkey. The system learned to recognize specific orthodontic skeletal malocclusions. After the training stage, the AI was tested in two groups: one group included Turkish patients whose records were not used in training, and the other group included patients from different ethnic backgrounds who were treated at a clinic in Belgium. This design allows researchers to see if the AI works equally well for people of different backgrounds.\n\nOnly photographs and X-rays taken before orthodontic treatment are used in the study, and all data are anonymized so that no personal information is shared. The images must meet certain quality standards. For example the head must be in natural position, with no beards, scars, or previous orthodontic treatment that might affect the image. Patients who do not meet these criteria are not included.\n\nThe AI program analyzes the profile photographs, prepares them for evaluation by adjusting and standardizing the images, and then tries to decide each patient has which malocclusion. The results from Turkish patients and patients from other ethnic groups are compared to see if the system makes fair and accurate decisions for everyone.\n\nThe purpose of this study is not to test a new treatment, but to understand how well AI can recognize orthodontic problems in different populations. This information is important because AI systems are increasingly being used in healthcare, and they need to be fair and accurate for all patients, not just those from one group.\n\nBy participating, patients help researchers learn whether AI in orthodontics is reliable across diverse communities. This knowledge can guide future improvements in AI technology, ensuring that it supports orthodontists in providing safe, equal, and effective care for everyone.",[29,89,90,91],"Class II Div 1 Malocclusion","Class II Division 2 Malocclusion","Class III Malocclusion",[93,94,95,96,97],"Artificial Intelligence","Deep Learning","Ethnic Bias","Machine Learning","Orthodontics","2025-11-28",{"date":100,"type":41},"2025-12-05",{"date":102,"type":41},"2025-01-06",{"date":104,"type":21},"2026-08-11",{"name":106,"class":48},"Bezmialem Vakif University",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":82,"sex":16,"minAge":114,"maxAge":115,"enrollmentInfo":116,"targetDuration":4,"studyType":22,"phases":118,"briefSummary":119,"conditions":120,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":49},"100566211","assessment-of-treatment-efficacy-using-smile-arc-marginal-ridge-approach-versus-mbt-chart-method-for-bracket-positioning-100566211","NCT06652230","Assessment of Treatment Efficacy Using Smile Arc Marginal Ridge Approach Versus MBT Chart Method for Bracket Positioning","Assessment of Treatment Efficacy Using Smile Arc Marginal Ridge Approach Versus MBT Chart Method for Bracket Positioning: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Orthodontic patients aged 11-30 years old.\n* Mild or moderate crowding not requiring tooth extraction.\n* Full permanent dentition including fully erupted 7s not necessarily 8s.\n* Good oral hygiene.\n* Skeletal and dentoalveolar class I malocclusion.\n\nExclusion Criteria:\n\n* Systemic disease potentially affecting the study outcome.\n* Cleft lip and palate\u002Fsyndromic patients.\n* Any signs or symptoms of temporomandibular disorders (TMD).\n* Previous orthodontic treatment.\n* Pregnant females.\n* Chronic use of medications.","11 Years","30 Years",{"count":117,"type":21},30,[24],"The goal of this randomized clinical trial is to evaluate the effect of Smile Arc Marginal Ridge Approach (SAMRA) versus MBT chart method for bracket positioning on orthodontic treatment results.\n\nThe main questions it aims to answer are:\n\nIs there a difference in orthodontic treatment results between smile arc marginal ridge approach (SAMRA) and MBT chart method for bracket positioning?\n\nDoes SAMRA provide more accurate orthodontic results and reduce the number of archwire bendings and brackets repositioning needed during finishing?\n\nThe investigators will compare Smile Arc Marginal Ridge Approach (SAMRA) with MBT Chart Method (gold standard) to see if SAMRA provides more accurate orthodontic results and reduce the need for archwire bendings and brackets repositioning during finishing.\n\nParticipants will:\n\n* Undergo orthodontic treatment and divided into two groups, Group A (SAMRA) and Group B (MBT Chart Method).\n* 0.018-inch MBT brackets will be used in both groups.\n* Follow ups every 1 month will take place to change the archwires after becoming passive.\n* After leveling and alignment is completed, orthodontic treatment results, number of archwire bendings and brackets repositioning needed will be determined to see which type of intervention is better or if both provide similar results.",[29],"2024-10-18",{"date":123,"type":41},"2024-10-22",{"date":125,"type":41},"2024-08-01",{"date":127,"type":21},"2025-08",{"name":129,"class":48},"Cairo University"]