[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"clinical-study\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:clinical-study":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100604990","deep-marginal-elevation-and-the-periodontal-microenvironment--dme-pm--100604990",false,"NCT07156695","Deep Marginal Elevation and the Periodontal Microenvironment ( DME-PM )","Deep Marginal Elevation and Its Impact on Periodontal Microenvironment: Microbiological, Clinical, and Radiographic Study","Inclusion Criteria:\n\n* Patients aged 18-60 years.\n* Diagnosed with Class II dental caries requiring restoration.\n* Presence of a healthy contralateral tooth (control side).\n* Willingness to participate and comply with follow-up visits.\n\nExclusion Criteria:\n\n* Systemic diseases (e.g., diabetes, autoimmune disorders).\n* Periodontal disease or active infection.\n* Use of anti-inflammatory medications within the last month.\n* Pregnancy or lactation.","ALL","18 Years","60 Years",{"count":20,"type":21},36,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to evaluate the impact of the dental restorative procedure known as Deep Marginal Elevation (DME) on periodontal health, including gingival and bone status, in patients with deep dental caries. Gingival fluid samples will be collected, and radiographic assessments will be performed to monitor changes in inflammation and bone levels. The findings are expected to provide insights into how DME influences gingival and bone health.",[27,28,29,30,31],"Deep Marginal Elevation","Periodontal Microenvironment","Microbiological Study","Clinical Study","Radiographic Study","RECRUITING","2025-09-03",{"date":35,"type":36},"2025-09-05","ACTUAL",{"date":38,"type":36},"2025-08-01",{"date":40,"type":21},"2026-01-01",{"name":42,"class":43},"Tanta University","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":44},"100561279","clinical-trial-recruitment-and-retention-strategies-for-family-members-in-the-icu-100561279","NCT06588101","Clinical Trial Recruitment and Retention Strategies for Family Members in the ICU","Clinical Trial Recruitment and Retention Strategies for Family Members in the Intensive Care Unit: A Study Within A Trial Randomized Design","SWAT","Inclusion Criteria:\n\n* Has family member admitted to an intensive care unit.\n* Expected hospital stay \\> 48 hours\n* Able to participate in English or French\n\nExclusion Criteria:\n\n* Has another family member participating in the trial\n* Repeat admissions within the study period",{"count":54,"type":21},160,[24],"There is a need to identify strategies that improve the conduct of clinical trials involving family members of intensive care unit (ICU) patients. The purpose of the present study is to evaluate recruitment and retention strategies for clinical trials involving family members of ICU patients. 4 strategies (2 recruitment and 2 retention) will be tested. Investigators will integrate the strategies into three existing studies that involve family members of ICU patients. Participants will be randomized using a 2x2 factorial design. The co-primary outcomes are recruitment percentage (participants enrolled\u002Fparticipants approached) and retention percentage (participants completing follow-up\u002Fparticipants enrolled).",[58,59,30,60,61,62,63,64],"Family Members","Recruitment","Retention","Recruitment of Participants","Study Enrollment","Retention of Participants","Compensation Incentives","2025-05-29",{"date":67,"type":36},"2025-06-04",{"date":69,"type":36},"2024-05-01",{"date":71,"type":21},"2026-12-31",{"name":73,"class":43},"Lady Davis Institute",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":81,"targetDuration":83,"studyType":84,"phases":4,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":44},"100547508","effect-of-vibration-capsule-on-different-subtypes-of-functional-constipation-100547508","NCT06408883","Effect of Vibration Capsule on Different Subtypes of Functional Constipation","A Prospective Cohort Study On the Efficacy of Vibrating Capsule For Different Subtypes of Chronic Functional Constipation","Inclusion Criteria:\n\nPatients who can be diagnosed with functional constipation according to the Rome IV criteria.\n\nPatients who consent to participate in this trial and voluntarily sign the informed consent form (ICF).\n\nExclusion Criteria:\n\nPeople who are not eligible for surgery or refuse to undergo any abdominal surgery; People with known or suspected gastrointestinal obstruction, stenosis, diverticulum, bleeding, malformation, and fistula.\n\nPeople allergic to polymeric materials; People implanted with cardiac pacemakers and using gastrointestinal pacemakers; People with abdominal aortic aneurysms, gastrointestinal vascular lesions, ulcers, and lesions with bleeding tendencies.\n\nPeople with dysphagia; Pregnant women; People with severe depression and anxiety and severe acute gastrointestinal lesions.\n\nPeople with other conditions, so the investigator considers them not eligible for this study.",{"count":82,"type":21},600,"4 Weeks","OBSERVATIONAL","This study is a multi-center prospective cohort study, which plans to include 600 patients with chronic functional constipation to treat with Vibrabot capsules and patients will be grouped according to subtypes.\n\nDuring the study, the patients' basic information, baseline constipation status and treatment information, capsule intake during treatment, and concomitant medication will be collected. During the treatment phase, patients follow the doctor's advice to receive Vibrabot capsule treatment and maintain stable dietary intake and exercise according to the constipation diagnosis and treatment guidelines.\n\nDuring the study, patients need to fill in the relevant information during the treatment in the electronic questionnaire in a timely and truthful manner. The treatment effect of the patients is evaluated by assessing the number of occurrences of spontaneous bowel movements (SBM) and complete spontaneous bowel movements (CSBM).",[30,87],"Chronic Functional Constipation",[89,90,87],"Vibrating Capsule","cohort study","NOT_YET_RECRUITING","2024-05-07",{"date":94,"type":36},"2024-05-10",{"date":96,"type":21},"2024-06-01",{"date":98,"type":21},"2026-07-01",{"name":100,"class":43},"Changhai Hospital"]