[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"clotting-factor-deficiency\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:clotting-factor-deficiency":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100487595","embolization-in-hereditary-coagulopathies-100487595",false,"NCT05629130","Embolization in Hereditary Coagulopathies","EHCO","Inclusion Criteria:\n\n* Patients with hereditary coagulopathies with arthropathy (i.e., chronic synovitis due to hemarthrosis), with X-ray and MRI (documenting synovitis) followed up at the Hemophilia Center HC-FMUSP.\n\nExclusion Criteria:\n\n* Patients who do not complete the planned assessments\n* Patients who do not accept to continue with the study.","ALL",{"count":18,"type":19},30,"ESTIMATED","INTERVENTIONAL",[22],"NA","This is a longitudinal, prospective study, which will include 30 subjects with hereditary coagulopathies, with arthropathy, chronic synovitis resulting from hemarthrosis of the elbows, knees and\u002For ankles followed up at the Centro de Hemofilia HCFMUSP, after approval by the ethics and research committee.\n\nThey will undergo imaging tests (X-rays and Magnetic Resonance of knee, elbow, or ankle), physical, pain, quality of life and functional assessments (Hemophilia Joint Health Score, Functional Independence Score in Hemophilia, Perimeter, Test Timed up and Go, 30 second sit and stand test, Haemophilia - Adult - Quality of Life questionnaire (HAEM-A-QoL), Knee Injury and Osteoarthritis Outcome Score, EQ-5D, numerical rating scale for pain and embolization procedure (superselective embolization of target arteries with spherical microparticles Embosphere 100-300 micrometers (Biosphere Medical, Roissy, France), until partial vascular stasis and decharacterization of pathological synovial enhancement.\n\nThese evaluations will be performed at baseline, 1, 3, 6, 12, 24, 36, 48 and 60 months after the procedure.",[25,26,27,28,29,30],"Hemophilia","Embolization","Hemarthrosis","Clotting Factor Deficiency","Synovitis","Arthropathy","RECRUITING","2022-11-16",{"date":34,"type":35},"2022-11-29","ACTUAL",{"date":37,"type":19},"2023-01-16",{"date":39,"type":19},"2029-12-31",{"name":41,"class":42},"University of Sao Paulo General Hospital","OTHER"]