[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"coccydynia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:coccydynia":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,44,68,100,125,148,170],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100636321","ultrasound-guided-dextrose-prolotherapy-for-coccydynia-a-prospective-study-100636321",false,"NCT07564167","Ultrasound-Guided Dextrose Prolotherapy for Coccydynia: A Prospective Study","Evaluation of the Effectiveness of Dextrose Prolotherapy on Pain Severity and Functional Status in Patients With Coccydynia: A Prospective Study","Inclusion Criteria:\n\n* Age between 18 and 75 years\n* Pain persisting for ≥3 months and refractory to conservative treatment\n* Coccydynia of mechanical or idiopathic origin\n\nExclusion Criteria:\n\n* Age \\\u003C18 years or \\>75 years\n* Pregnancy\n* Allergy to the proliferant solution\n* Active infection\n* Use of anticoagulant medications\n* Presence of malignancy\n* Local abscess\n* Hemorrhagic diathesis\n* Certain types of septic arthritis\n* Parafunctional habits","ALL","18 Years","75 Years",{"count":20,"type":21},30,"ESTIMATED","INTERVENTIONAL",[24],"NA","Coccydynia is a musculoskeletal condition characterized by pain in the coccygeal region, particularly exacerbated by sitting, and is associated with impaired quality of life and functional limitation. Although various conservative and interventional treatment options are available, there remains a need for effective and safe alternative therapies, especially in treatment-resistant cases.\n\nProlotherapy is a regenerative treatment modality that aims to reduce pain and improve function by stimulating tissue repair, particularly in ligamentous structures. While there is increasing evidence supporting its effectiveness in mechanical musculoskeletal pain conditions, the literature regarding its use in coccydynia is limited.\n\nThe aim of this study is to evaluate the effect of dextrose prolotherapy on pain severity and functional status in patients diagnosed with coccydynia. This study is designed as a prospective, single-arm, open-label interventional study. Patients will receive 15% dextrose prolotherapy according to a standardized protocol. Pain severity will be assessed using the Visual Analog Scale (VAS), and functional status will be evaluated using the Dallas Pain Questionnaire before treatment and at 1 month after completion of the treatment.\n\nThis study aims to provide more comprehensive data on the effectiveness and safety of prolotherapy in coccydynia and to contribute to the currently limited evidence in the literature.",[27],"Coccydynia",[27,29,30],"Dextrose Prolotherapy","Ultrasound-Guided Injection","RECRUITING","2026-04-27",{"date":34,"type":35},"2026-05-04","ACTUAL",{"date":37,"type":35},"2026-01-15",{"date":39,"type":21},"2026-06-15",{"name":41,"class":42},"Gaziosmanpasa Research and Education Hospital","OTHER_GOV",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":56,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":43},"100635408","the-effectiveness-of-dextrose-prolotherapy-in-patients-with-coccydynia-100635408","NCT07552298","The Effectiveness of Dextrose Prolotherapy in Patients With Coccydynia","Inclusion Criteria:\n\n* Patients with coccydynia lasting longer than 6 months,\n* Those unresponsive to at least 6 months of conventional conservative treatment methods,\n* Those with coccygeal tenderness on palpation,\n* Patients aged between 18 and 65 years.\n\nExclusion Criteria:\n\n* Patients with a history of trauma within the last 3 months or postpartum coccydynia,\n* Those with lesions or infections at the injection site,\n* Those with dislocation or organic bone pathology of the coccyx observed on X-ray imaging,\n* Those with fecal or urinary incontinence,\n* Patients with poorly controlled diabetes mellitus,\n* Those with a history of malignancy,\n* Patients with a bleeding tendency (acquired or hereditary) \\[INR \\> 2 in patients using warfarin\\],\n* Those with a history of myelomeningocele,\n* Those diagnosed with spina bifida,\n* Patients with rheumatologic disease,\n* Those who have undergone coccyx injection or ganglion block within the last 3 months,\n* Patients with severe comorbidities.","65 Years",{"count":52,"type":21},40,[24],"In this prospective, randomized, controlled, double-blinded study, we aimed to evaluate the effects of Dextrose Prolotherapy injections in patients with coccydynia.",[27],[57,58],"prolotherapy","coccydynia","2026-04-20",{"date":32,"type":35},{"date":62,"type":35},"2025-06-15",{"date":64,"type":21},"2026-11-15",{"name":66,"class":67},"Istanbul University","OTHER",{"id":69,"slug":70,"hasResults":11,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":76,"targetDuration":4,"studyType":22,"phases":78,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":43},"100625735","osteopathic-manual-therapy-vs-ganglion-impar-block-for-chronic-coccydynia-100625735","NCT07426497","Osteopathic Manual Therapy vs Ganglion Impar Block for Chronic Coccydynia","Comparison of Osteopathic Manual Therapy and Ganglion Impar Block in Patients With Chronic Coccydynia","COCCY-OMT-GIB","Inclusion Criteria:\n\n* Age 18-75 years\n* Chronic coccygodynia ≥3 months\n* Baseline NRS ≥4\n* ODI ≥20\n* Failure of prior conservative treatment\n* Imaging excludes fracture, infection, or malignancy\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Acute coccygodynia\n* Prior spinal or coccygeal surgery\n* Malignancy\n* Pelvic fracture\n* Pregnancy\n* Coagulation disorder\n* Severe psychiatric disease\n* Prior osteopathic manual therapy or ganglion impar block",{"count":77,"type":21},100,[24],"Chronic coccydynia is a condition characterized by persistent pain in the coccyx region that can significantly impair sitting tolerance, daily activities, and quality of life. Various conservative and interventional treatment options have been described, including manual therapy techniques and ganglion impar block. However, the comparative effectiveness of these approaches remains unclear.\n\nThe aim of this randomized controlled study is to compare the effects of osteopathic manual therapy and ganglion impar block on pain intensity and functional disability in patients with chronic coccydynia. Participants will be randomly assigned to one of the two treatment groups. Pain severity will be assessed using the Numeric Rating Scale (NRS), and functional status will be evaluated with the Oswestry Disability Index (ODI) at baseline, week 3, and month 3.\n\nThe results of this study are expected to provide evidence regarding the relative effectiveness of these two commonly used treatment methods and to guide clinicians in selecting appropriate management strategies for patients with chronic coccydynia.",[27,81,82],"Chronic Pain","Coccygodynia",[84,85,86,87,88,89,90],"Chronic coccydynia","Ganglion impar block","Osteopathic manual therapy","Coccyx pain","Manual therapy","Interventional pain","Numeric Rating Scale","2026-02-22",{"date":93,"type":35},"2026-02-24",{"date":95,"type":35},"2025-08-28",{"date":97,"type":21},"2026-02-16",{"name":99,"class":67},"Istanbul Medeniyet University",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":50,"enrollmentInfo":106,"targetDuration":4,"studyType":22,"phases":107,"briefSummary":108,"conditions":109,"keywords":110,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":43},"100594585","comparison-of-ganglion-impar-radiofrequency-ablation-and-phenol-neurolysis-techniques-for-chronic-coccydynia-treatment-100594585","NCT07021365","Comparison of Ganglion Impar Radiofrequency Ablation and Phenol Neurolysis Techniques for Chronic Coccydynia Treatment","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Presence of chronic coccydynia lasting at least 3 months\n* Pre-procedural pain score of 4 or higher on the Numeric Rating Scale (NRS)\n* Patients who have undergone a ganglion impar block within the last 3 months and experienced limited benefit (i.e., less than 50% reduction in pain compared to pre-treatment) and\u002For short-term relief (less than 4 weeks)\n\nExclusion Criteria:\n\n* History of surgery involving the sacrococcygeal region\n* Prior treatment with ganglion impar phenol neurolysis or radiofrequency ablation\n* Coagulopathies (bleeding disorders)\n* Infection\n* Spondylolisthesis, scoliosis, or lumbar spinal stenosis\n* Malignancy\n* Pregnancy\n* History of allergic reaction to the administered injectates\n* History of major psychiatric illness",{"count":20,"type":21},[24],"Radiofrequency ablation and phenol neurolysis of the ganglion impar are methods used in cases unresponsive to medication, particularly in patients who derive short-term or partial relief from the initial ganglion impar block. In clinical practice, clinicians frequently use these two injections in patients with treatment-resistant pain who only partially benefit from the initial blockade procedure.\n\nTo date, the medical literature lacks a comprehensive study comparing the efficacy of radiofrequency ablation and phenol neurolysis in patients who partially benefit from ganglion impar block. Therefore, this study is designed to compare the effectiveness of these two methods in patients with chronic coccydynia.",[82,27],[111,112,113,114,58],"coccygodinia","chronic","radiofrequency ablation","phenol neurolysis","NOT_YET_RECRUITING","2025-06-13",{"date":118,"type":35},"2025-06-17",{"date":120,"type":21},"2025-07",{"date":122,"type":21},"2026-03",{"name":124,"class":67},"Marmara University",{"id":126,"slug":127,"hasResults":11,"nctId":128,"briefTitle":129,"officialTitle":129,"acronym":4,"eligibilityCriteria":130,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":50,"enrollmentInfo":131,"targetDuration":4,"studyType":22,"phases":132,"briefSummary":133,"conditions":134,"keywords":135,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":43},"100584225","ultrasound-guided-ganglion-impar-block-100584225","NCT06886568","Ultrasound Guided Ganglion Impar Block","Inclusion Criteria:\n\n* Age between 18-65 years.\n* Coccydynia persisting for at least three months.\n* Being scheduled for a ganglion impar block in the pain medicine outpatient clinic.\n* Having inadequate response to medical and conservative treatments.\n* Aggreeing to undergo the interventional procedure and participate in the study.\n\nExclusion Criteria:\n\n* Local infection at the injection site.\n* Bleeding disorders or diseases and drugs that may cause bleeding diatesis (e.g. renal failure, liver failure, anticoagulant treatments)\n* History of allergic reaction to the medications to be used.\n* Pregnancy",{"count":20,"type":21},[24],"The aim of this study is to evaluate feasibility, reliability and short term effectiveness of ganglion impar block with ultrasound in patients with chronic coccygodinia.",[27,81],[27,136,137,138],"pain","ultrasound guided injection","ganglion impar","2025-03-19",{"date":141,"type":35},"2025-03-20",{"date":143,"type":21},"2025-04-01",{"date":145,"type":21},"2025-07-15",{"name":147,"class":42},"Başakşehir Çam & Sakura City Hospital",{"id":149,"slug":150,"hasResults":11,"nctId":151,"briefTitle":152,"officialTitle":153,"acronym":4,"eligibilityCriteria":154,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":50,"enrollmentInfo":155,"targetDuration":4,"studyType":22,"phases":157,"briefSummary":158,"conditions":159,"keywords":160,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":43},"100582100","comparison-of-impar-ganglion-block-and-sacral-erector-spinae-plane-block-in-patients-with-coccygodynia-100582100","NCT06858917","Comparison of Impar Ganglion Block and Sacral Erector Spinae Plane Block in Patients with Coccygodynia","Comparison of Impar Ganglion Block and Sacral Erector Spinae Plane Block for Chronic Coccygodynia: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Those who have had chronic coccygodynia for at least 3 months\n* Being between the ages of 18-65\n* Patients who do not respond to conservative treatments (analgesics, physical therapy modalities etc.) and are scheduled for interventional pain procedures\n\nExclusion Criteria:\n\n* Patients who have undergone surgery to the coccyx region\n* Having undergone an interventional pain procedure in the lumbar, sacral and coccyx regions within the last year\n* Patients with systemic infection, local infection at the application site, and coagulopathy\n* Pregnant and breastfeeding patients\n* Having endocrine or rheumatological disease that may affect the musculoskeletal system in the relevant region and lead to diagnostic complexity (such as spondyloarthropathy)\n* Patients with musculoskeletal system pathology that may contribute to symptoms in the relevant region and affect the evaluation of treatment results (such as lumbar disc herniation, sacroiliitis, spinal stenosis)\n* Those with lumbar, sacral or coccygeal vertebra fractures\n* Those with a history of allergic reactions to the contents of the injectate to be administered during an interventional pain procedure (especially contrast agent and local anesthetic)\n* Those with mental disorders that may affect the evaluation during the follow-up periods during the study",{"count":156,"type":21},130,[24],"Coccygodynia is a condition that causes pain in the tailbone (coccyx) area. While it can develop after trauma, such as a fall or fracture, in some cases, no clear cause is identified. Patients who do not experience relief from standard treatments like pain medications, physical therapy, and posture adjustments may be referred to specialized pain management clinics for further treatment options.\n\nSeveral interventional procedures can help manage coccygodynia. These include impar ganglion block, radiofrequency ablation, caudal epidural steroid injections, sacral erector spinae plane (ESP) block, and coccygeal nerve blocks. These procedures are commonly performed in pain treatment centers and aim to reduce discomfort by targeting specific nerves responsible for transmitting pain signals.\n\nImpar ganglion block is one of the most frequently used treatments for coccygodynia. It involves injecting a local anesthetic, with or without steroids, into a small nerve cluster in front of the sacrococcygeal joint. This procedure is performed under ultrasound and\u002For fluoroscopic (X-ray) guidance in a sterile operating room setting to ensure accuracy and safety. While the goal is to relieve pain, potential risks include temporary worsening of pain, bleeding, infection, or, in rare cases, rectal injury.\n\nAnother interventional option is the sacral erector spinae plane (ESP) block, a technique that delivers local anesthetic under the erector spinae muscles in the sacrum. This procedure, also performed under ultrasound guidance in a sterile environment, is used to block pain signals from the coccyx and surrounding areas. Like the impar ganglion block, it can be effective for pain relief, but possible side effects include temporary pain increase, bleeding, and infection at the injection site.\n\nBoth procedures are minimally invasive.",[82,27],[82,27,161,162],"impar block","sacral erector spinae plane block",{"date":164,"type":35},"2025-03-24",{"date":166,"type":35},"2025-03-15",{"date":168,"type":21},"2025-10-15",{"name":147,"class":42},{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":177,"enrollmentInfo":178,"targetDuration":4,"studyType":22,"phases":180,"briefSummary":181,"conditions":182,"keywords":185,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":189,"lastUpdatePostDateStruct":190,"startDateStruct":192,"completionDateStruct":194,"leadSponsor":196,"locationsCount":43},"100566284","efficacy-of-interventional-methods-used-in-the-treatment-of-coccydynia-100566284","NCT06653179","Efficacy of Interventional Methods Used in the Treatment of Coccydynia","Comparison of the Efficacy of Sacral Erector Spinae Plane Block and Caudal Epidural Injection on Chronic Coccydynia: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Chronic coccydynia unresponsive to conservative treatment\n* Male and female population aged 18-70\n* No previous interventional procedure performed during the treatment process\n\nExclusion Criteria:\n\n* Coagulation disorders\n* Infections in the areas to be treated\n* Allergy to local anesthesia\n* Socio-cultural inadequacy\n* Mental retardation\n* Pregnancy\n* Previous interventional procedure performed\n* Patient refusal of the interventional procedure\n* Presence of malignancy in the coccygeal region\n* Previous surgery in the coccygeal region","70 Years",{"count":179,"type":21},94,[24],"This study aims to evaluate the effectiveness of sacral erector spinae plane block and caudal epidural injection in patients with coccydynia resistant to conservative treatments. Ultrasound guidance will be used for sacral erector spinae plane block, while fluoroscopic guidance will be applied for caudal epidural injection. The effectiveness of these treatments will be assessed through face-to-face questionnaires, the Numerical Rating Scale and the Paris Functional Coccydynia Scale at first, fourth and twelfth-week follow-ups.",[27,183,184],"Erector Spinae Plane Block","Caudal Block",[186,187,188],"Sacral Erector Spinae Plane Block","Caudal. Epidural Injection","Chronic Coccydynia","2024-10-22",{"date":191,"type":35},"2024-10-23",{"date":193,"type":21},"2024-11-15",{"date":195,"type":21},"2025-11-15",{"name":197,"class":42},"Ankara Etlik City Hospital"]