[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cochlear-implant-listeners\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cochlear-implant-listeners":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100645169","patient-oriented-research-to-optimize-cochlear-implant-outcomes-100645169",false,"NCT07678879","Patient-Oriented Research to Optimize Cochlear Implant Outcomes","Inclusion Criteria:\n\n1. Adults between ages of 18 years and 95 years\n2. Native language is American English\n3. Have one or two CIs from any of the three FDA-approved CI manufacturers (Cochlear Americas, Advanced Bionics, MED-EL).\n4. Experience of \\>6 of CI use.\n\nExclusion Criteria:\n\n1. Score 24 or below on a visual Mini-Mental State Exam (MMSE; Folstein et al., 1975) to rule out dementia\n2. Known diagnosis of dementia\n3. Under the age of 18 years\n4. Unable to read and write in English (WRAT score \\\u003C70)\n5. Poorer than 20\u002F40 near vision on near-vision screening.","ALL","18 Years","95 Years",{"count":19,"type":20},100,"ESTIMATED","INTERVENTIONAL",[23],"NA","The rationale is that only through understanding how individual Cochlear Implant (CI) patients respond to interventions investigators further develop precision-medicine approaches to optimize outcomes. In the proposed research study to investigate the hypotheses, investigators will address two Specific Aims:\n\nSpecific Aim #1: Define the auditory (bottom-up), cognitive-linguistic (top-down), and functional neuroimaging profiles of adult CI users. Investigators will enroll experienced CI users (\\> 6 months of CI use).\n\nSpecific Aim #2: Determine the feasibility of \"auditory\" (bottom-up) and \"cognitive\" (top-down) interventions to improve speech processing in adult CI users.\n\nThe main hypothesis is that the two interventions are feasible. Investigators also hypothesize that our study protocol will detect the variance in auditory processing profiles and that investigators will show promise in improving both speech processing (using speech recognition and Functional Near-Infrared Spectroscopy (fNIRS) responses)) and real-world functioning (using patient-reported measures), compared with no intervention.\n\nAdditional hypotheses to be explored are that baseline profile (as defined in Aim #1) will impact the magnitude of participants' responses to the interventions, as will order of interventions (Auditory-Cognitive vs. Cognitive-Auditory, AC vs CA).",[26,27,28,29],"Cochlear Implant","Cochlear Implant Users","Cochlear Implant Recipients","Cochlear Implant Listeners",[31,32,33,34,35],"CI users","CI","cochlear implant","cochlear implant user","cochlear","NOT_YET_RECRUITING","2026-06-24",{"date":39,"type":40},"2026-07-01","ACTUAL",{"date":42,"type":20},"2026-07",{"date":44,"type":20},"2032-06",{"name":46,"class":47},"Vanderbilt University Medical Center","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":15,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":21,"phases":59,"briefSummary":60,"conditions":61,"keywords":62,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":48},"100595701","pediatric-cochlear-implant-remote-programming-and-assessment-100595701","NCT07035873","Pediatric Cochlear Implant Remote Programming and Assessment","Inclusion Criteria:\n\n* Cochlear implantation with an Advanced Bionics cochlear implant in at least one ear.\n* At least 6 months post-implantation listening experience and at least 2 weeks of listening experience with Marvel cochlear implant external processor.\n* Speech perception performance of at least 40% correct on standard of care speech perception measures in quiet for the ear to be used in the study\n* Ages 13 years to 20 years, inclusive\n* Ability and willingness to participate in remote programming sessions and self-administered assessment measures\n\nExclusion Criteria:\n\n* Children under the age of 13\n* Speech perception performance \\\u003C 40% on SOC speech perception measures\n* Cognitive or language deficits that preclude ability and willingness to participate in remote programming sessions and self-administered assessment measures, as identified by eMR diagnoses and the participant's primary clinical audiologist judgement.","13 Years","20 Years",{"count":58,"type":20},15,[23],"This is a prospective, interventional study to evaluate efficacy and end user satisfaction of remote cochlear implant programming in the pediatric population. Additionally, this study will evaluate the long-term replicability of digital audio streaming (DAS) self-assessment speech perception measures via iOS mobile application.",[29],[63,33,64,65],"pediatric","remote programming","telehealth","RECRUITING","2026-04-07",{"date":69,"type":40},"2026-04-13",{"date":71,"type":40},"2025-01-15",{"date":73,"type":20},"2027-03-31",{"name":75,"class":47},"Nationwide Children's Hospital"]