[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cochlear-implant-users\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cochlear-implant-users":24},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,38,70,93,115,139],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":26,"lastUpdatePostDateStruct":27,"startDateStruct":30,"completionDateStruct":32,"leadSponsor":34,"locationsCount":37},"100601765","early-cochlear-implant-use-100601765",false,"NCT07114744","Early Cochlear Implant Use","Inclusion Criteria:\n\n1. Postlingually deaf cochlear implant users\n2. severe or profound hearing loss\n3. who do not have other diagnoses communicative or cognitive disorders.\n4. Test population: no prior experience with cochlear implants (recruitment happens prior to cochlear implantation).\n5. Control population: subjects who have used the same stimulation strategy since initial stimulation, who note no continuing improvements or changes with their devices with respect to speech comprehension.\n\nExclusion Criteria:\n\n1. Diagnosed cognitive or communicative disorders (other than deafness)\n2. Below 18 years of age\n3. Above the age of 85 years old.","ALL","18 Years","85 Years",{"count":19,"type":20},25,"ESTIMATED","OBSERVATIONAL","This observational study will examine newly activated cochlear implant users and determine whether their abilities to discern simple sounds change and relate to improved speech perception. Take-home computers and test-equipment will be sent home, and subjects will complete approximately 25 test sessions over the first 3 months of cochlea implant use. Then, subjects will be tested 3 more times in the laboratory until 1 year-post activation. The primary objective is to determine and quantify how sounds change and speech perception improves over the course of early cochlear implant use.",[24],"Cochlear Implant Users","RECRUITING","2026-06-29",{"date":28,"type":29},"2026-07-01","ACTUAL",{"date":31,"type":29},"2025-06-11",{"date":33,"type":20},"2027-07-01",{"name":35,"class":36},"NYU Langone Health","OTHER",1,{"id":39,"slug":40,"hasResults":11,"nctId":41,"briefTitle":42,"officialTitle":42,"acronym":4,"eligibilityCriteria":43,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":44,"enrollmentInfo":45,"targetDuration":4,"studyType":47,"phases":48,"briefSummary":50,"conditions":51,"keywords":55,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":37},"100645169","patient-oriented-research-to-optimize-cochlear-implant-outcomes-100645169","NCT07678879","Patient-Oriented Research to Optimize Cochlear Implant Outcomes","Inclusion Criteria:\n\n1. Adults between ages of 18 years and 95 years\n2. Native language is American English\n3. Have one or two CIs from any of the three FDA-approved CI manufacturers (Cochlear Americas, Advanced Bionics, MED-EL).\n4. Experience of \\>6 of CI use.\n\nExclusion Criteria:\n\n1. Score 24 or below on a visual Mini-Mental State Exam (MMSE; Folstein et al., 1975) to rule out dementia\n2. Known diagnosis of dementia\n3. Under the age of 18 years\n4. Unable to read and write in English (WRAT score \\\u003C70)\n5. Poorer than 20\u002F40 near vision on near-vision screening.","95 Years",{"count":46,"type":20},100,"INTERVENTIONAL",[49],"NA","The rationale is that only through understanding how individual Cochlear Implant (CI) patients respond to interventions investigators further develop precision-medicine approaches to optimize outcomes. In the proposed research study to investigate the hypotheses, investigators will address two Specific Aims:\n\nSpecific Aim #1: Define the auditory (bottom-up), cognitive-linguistic (top-down), and functional neuroimaging profiles of adult CI users. Investigators will enroll experienced CI users (\\> 6 months of CI use).\n\nSpecific Aim #2: Determine the feasibility of \"auditory\" (bottom-up) and \"cognitive\" (top-down) interventions to improve speech processing in adult CI users.\n\nThe main hypothesis is that the two interventions are feasible. Investigators also hypothesize that our study protocol will detect the variance in auditory processing profiles and that investigators will show promise in improving both speech processing (using speech recognition and Functional Near-Infrared Spectroscopy (fNIRS) responses)) and real-world functioning (using patient-reported measures), compared with no intervention.\n\nAdditional hypotheses to be explored are that baseline profile (as defined in Aim #1) will impact the magnitude of participants' responses to the interventions, as will order of interventions (Auditory-Cognitive vs. Cognitive-Auditory, AC vs CA).",[52,24,53,54],"Cochlear Implant","Cochlear Implant Recipients","Cochlear Implant Listeners",[56,57,58,59,60],"CI users","CI","cochlear implant","cochlear implant user","cochlear","NOT_YET_RECRUITING","2026-06-24",{"date":28,"type":29},{"date":65,"type":20},"2026-07",{"date":67,"type":20},"2032-06",{"name":69,"class":36},"Vanderbilt University Medical Center",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":47,"phases":80,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":37},"100613149","investigating-the-acceptance-and-performance-of-low-energy-audio-streaming-in-nucleus-8-and-kanso-3-sound-processors-by-experienced-cochlear-implant-users-100613149","NCT07262827","Investigating the Acceptance and Performance of Low Energy Audio Streaming in Nucleus 8 and Kanso 3 Sound Processors by Experienced Cochlear Implant Users","A Pre-market, Prospective, Within-subject, Open-label, Interventional Investigation of Acceptance and Performance of Wireless Streaming Via Low Energy Audio Introduced Into the Firmware of the Nucleus 8 and Kanso 3 Sound Processors Worn by Experienced Adult Cochlear Implant Recipients","STREAM","Inclusion Criteria:\n\n1. Aged 18 years or older\n2. Implanted with at least one of the CI1000 Series, CI600 Series, CI500 Series, Freedom Series or N24 Series cochlear hearing implants.\n3. At least 3 months experience with a cochlear hearing implant\n4. Demonstrated ability to score 30% or more at +15 SNR with Cochlear implant alone on a sentence in noise test.\n5. Willingness to participate in and to comply with all requirements of the protocol\n6. Fluent speaker in English as determined by the investigator\n7. Willing and able to provide written informed consent.\n\nExclusion Criteria:\n\n1. Additional disabilities that would prevent participation in evaluations\n2. Unrealistic expectations on the part of the participant, regarding the possible benefits, risks and limitations that are inherent to the procedures\n3. Unable or unwilling to comply with the requirements of the clinical investigation as determined by the Investigator.\n4. Investigator site personnel directly affiliated with this study and\u002For their immediate families; immediate family is defined as a spouse, parent, child, or sibling.\n5. Current participation, or participation in another interventional clinical study\u002Ftrial in the past 30 days, involving an investigational drug or device (unless Cochlear sponsored and determined by Investigator or Sponsor to not impact this investigation).",{"count":79,"type":20},20,[49],"This study aims to investigate acceptance and performance of the Bluetooth Low Energy Audio-enabled (LE Audio) firmware in the Nucleus 8 Processing Unit, Kanso 3 Nexa Sound Processor, and the Kanso 3 Sound Processor. The investigation includes actual use (take home) of LE Audio firmware releases and the new GN ReSound LE Audio wireless accessories, including the Multi-Mic+, for use in the real-world. Using the final versions of firmware, speech perception performance in noise will be investigated using the Nucleus 8 and Kanso 3 Sound Processors streaming via a Multi-Mic+.",[24],"2026-05-26",{"date":85,"type":29},"2026-05-28",{"date":87,"type":29},"2026-03-12",{"date":89,"type":20},"2027-10",{"name":91,"class":92},"Cochlear","INDUSTRY",{"id":94,"slug":95,"hasResults":11,"nctId":96,"briefTitle":97,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":99,"sex":15,"minAge":100,"maxAge":16,"enrollmentInfo":101,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":103,"conditions":104,"keywords":4,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":37},"100632138","effects-of-binaural-hearing-on-listening-effort-and-cognitive-development-in-mandarin-speaking-children-with-cochlear-implants-100632138","NCT07509788","Effects of Binaural Hearing on Listening Effort and Cognitive Development in Mandarin-speaking Children With Cochlear Implants","CI Group Inclusion Criteria:\n\n1. Aged 6-18 years\n2. Normal vision, including corrected vision\n3. Prelingual deafness with bilateral severe-to-profound sensorineural hearing loss, with unilateral or bilateral cochlear implantation\n4. Good speech perception ability, with Categories of Auditory Performance-II (CAP-II) score of 5 or above\n5. Cooperative with testing, with signed informed consent from parent or guardian\n\nNormal-Hearing Control Group Inclusion Criteria:\n\n1. Aged 6-18 years\n2. Normal vision, including corrected vision\n3. Bilateral pure-tone average at 250, 500, 1000, 2000, and 4000 Hz of 30 dB HL or less\n4. Cooperative with testing, with signed informed consent from parent or guardian\n\nExclusion Criteria (All Groups):\n\n1. Diagnosed neurological or psychiatric disorders\n2. Absence of informed consent from parent or guardian\n3. Other conditions deemed unsuitable for participation by the investigators",true,"6 Years",{"count":102,"type":20},360,"The goal of this observational study is to learn how listening effort affects brain development and daily life in school-aged children (ages 6-18) who use cochlear implants (CIs), which are electronic devices surgically placed in the ear to help children with severe hearing loss hear sounds. The main questions it aims to answer are:\n\nDo children with CIs use more mental energy to listen than children with normal hearing, and does this extra effort slow their brain development over time? Does listening with two ears (bilateral CIs or a CI plus a hearing aid) reduce listening effort compared to listening with one ear only? How does listening effort affect children's ability to get along with others and adapt to daily life?\n\nResearchers will compare children with CIs to children with normal hearing to see if differences in listening effort lead to differences in cognitive development, social skills, and quality of life over 3 years.\n\nParticipants will:\n\nComplete hearing tests to measure how well they understand speech in quiet and noisy settings Wear a functional near-infrared spectroscopy (fNIRS) headset and eye-tracking glasses during a short listening task (about 15-40 minutes) so researchers can measure brain activity and pupil size changes - these are safe, painless, and non-invasive ways to see how hard the brain is working to listen Take thinking and memory tests appropriate for their age Have a parent or guardian answer questions about their child's social skills and daily communication Return for the same set of tests at 1 year and 3 years after the first visit\n\nThis study does not involve any new treatment or change to a child's current care. All children will continue their regular medical and rehabilitation plans. The study aims to enroll 360 children (120 with normal hearing and 240 with cochlear implants) at Guangdong Provincial People's Hospital in China. Results may help doctors better understand when children with CIs need extra support and how to improve rehabilitation strategies.",[24,105],"Cochlear Hearing Loss","2026-04-10",{"date":108,"type":29},"2026-04-15",{"date":110,"type":29},"2025-10-01",{"date":112,"type":20},"2030-10-01",{"name":114,"class":36},"Xiong hao",{"id":116,"slug":117,"hasResults":11,"nctId":118,"briefTitle":119,"officialTitle":120,"acronym":4,"eligibilityCriteria":121,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":122,"targetDuration":4,"studyType":47,"phases":123,"briefSummary":124,"conditions":125,"keywords":126,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":37},"100617841","assessment-of-a-method-to-improve-cochlear-implant-users-speech-perception-in-noisy-environments-while-maintaining-their-ability-to-determine-where-a-sound-originates-from-100617841","NCT07323862","Assessment of a Method to Improve Cochlear Implant Users' Speech Perception in Noisy Environments While Maintaining Their Ability to Determine Where a Sound Originates From","Spatially Transparent Binaural Beamforming for Noise Reduction for Cochlear Implant Processors","Inclusion Criteria:\n\n* Participants must have bilateral cochlear implants from Cochlear or Advanced Bionics\n\nExclusion Criteria:\n\n* Non-native English speakers",{"count":19,"type":20},[49],"The goal of this clinical trial is to determine if a new algorithm can improve speech perception for cochlear implant users. The main questions it aims to answer \\[is\u002Fare\\]:\n\n* Does the algorithm improve speech perception in noisy environments?\n* Does the algorithm allow listeners to determine where a sound is coming from?\n\nParticipants will\n\n* Listen to and repeat sentences presented in the presence of noise\n* Indicate the location that sounds originated from",[24],[127,128,129],"Beamforming","Speech perception in noise","Localization","2026-01-06",{"date":132,"type":29},"2026-01-07",{"date":134,"type":20},"2026-01-01",{"date":136,"type":20},"2026-08-31",{"name":138,"class":36},"University of Illinois at Urbana-Champaign",{"id":140,"slug":141,"hasResults":11,"nctId":142,"briefTitle":143,"officialTitle":143,"acronym":4,"eligibilityCriteria":144,"healthyVolunteers":99,"sex":15,"minAge":16,"maxAge":145,"enrollmentInfo":146,"targetDuration":4,"studyType":47,"phases":148,"briefSummary":149,"conditions":150,"keywords":151,"overallStatus":25,"whyStopped":4,"lastUpdateSubmitDate":153,"lastUpdatePostDateStruct":154,"startDateStruct":156,"completionDateStruct":158,"leadSponsor":160,"locationsCount":161},"100614426","cochlear-implants-and-listening-effort-the-interaction-of-cognitive-and-sensory-constraints-100614426","NCT07279441","Cochlear Implants and Listening Effort: the Interaction of Cognitive and Sensory Constraints","Inclusion Criteria:\n\n* Subjects will be otherwise healthy normal-hearing and cochlear implant (CI) adult listeners (between 18 and 80 years old).\n\nExclusion Criteria:\n\n* Individuals below 18 years of age.\n* Individuals with evidence of neurologic, vascular or psychiatric disease or dementia, and taking medications that might interfere with task performance.\n* Individuals with a history of language disorders (besides those associated with hearing loss for the CI users). Individuals who are non-native speakers of American English.","80 Years",{"count":147,"type":20},460,[49],"This study examines how cochlear implant users understand and comprehend speech in realistic communication situations. Through six experiments measuring listening effort via pupillometry and discourse comprehension, we will investigate how linguistic context, cognitive demands, and processing time affect speech understanding in CI users, and in normal-hearing controls) to identify factors underlying communication resilience versus vulnerability and develop improved, ecologically valid assessment and rehabilitation strategies.",[24],[57,152],"Cochlear implant","2025-12-09",{"date":155,"type":29},"2025-12-12",{"date":157,"type":29},"2025-01-02",{"date":159,"type":20},"2030-01-02",{"name":35,"class":36},2]