[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cochlear-implants\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cochlear-implants":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,41,66,97,123,144,165,192,219,248],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100473956","anatomy-based-fitting-in-unexperienced-cochlear-implant-users-100473956",false,"NCT05451628","Anatomy-Based Fitting in Unexperienced Cochlear Implant Users","ABFmulti","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Post-lingual onset of severe to profound sensory-neural hearing loss in the implanted ear(s)\n* Post-operative Computed Tomography (CT) scan of the CI electrode available\n* Pre-operative result of pure-tone audiometry, speech test in quiet and in noise available\n* Subject implanted with MED-EL cochlear implant(s)\n* Subjects received a Flex28, FlexSoft or Standard electrode\n* Subject planned to receive a SONNET 2, SONNET 3 or RONDO 3 audio processor on the newly implanted side\n* Audio processor not yet activated on the newly implanted side\n* The most apical active electrode contact has to be inserted at least 450°\n* Minimum of 10 active channels can be activated\n* Fluent in the language of the test centre\n* Signed and dated Informed Consent Form (ICF) before the start of any study-specific procedure\n\nExclusion Criteria:\n\n* Lack of compliance with any inclusion criteria\n* Electric Acoustic Stimulation (EAS) user (user of an EAS audio processor)\n* Implanted with C40+, C40X and C40C\n* Implanted with an Auditory Brainstem Implant (ABI) or Split electrode array\n* Anything that, in the opinion of the Investigator, would place the subject at increased risk or pre-clude the subject's full compliance with or completion of the study","ALL","18 Years",{"count":19,"type":20},40,"ESTIMATED","INTERVENTIONAL",[23],"NA","Severe to profound hearing loss affects 0,8% of the global population. For these people, a conventional hearing aid often does not provide sufficient benefit. However, these people can benefit from a cochlear implant (CI). A CI needs to be individually programmed (fitted) for each recipient. A fitting \"map\" is defined as a set of electrical parameters that are individually adapted to a recipient's needs to achieve optimal sound perception. At present, most CI recipients are fitted with a default frequency allocation map that doesn't take individual variability in size and shape of the cochlea into account. In this study, a fitting strategy based on the post-operative CT scan, that will allow the audiologist to set a frequency-band distribution for CI fitting that may be more closely aligned to the natural tonotopic frequency distribution of a normal hearing cochlea, will be evaluated.",[26,27],"Cochlear Implants","Sensorineural Hearing Loss","RECRUITING","2026-06-29",{"date":31,"type":32},"2026-07-02","ACTUAL",{"date":34,"type":32},"2022-03-30",{"date":36,"type":20},"2027-01",{"name":38,"class":39},"Universitair Ziekenhuis Brussel","OTHER",2,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":49,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":56,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":4},"100632205","ci-spatial-orientation-study-100632205","NCT07510659","CI Spatial Orientation Study","Effect of Cochlear Implant Stimulation on Spatial Orientation in Adult Users","CISPACE","Inclusion Criteria:\n\n* \\> 18 years\n* Ability to comply with study procedures\n* Use of a CI (unilateral or bilateral) for minimum 12 months\n* Signed, written informed consent\n\nExclusion Criteria:\n\n* Vulnerable individuals\n* Cognitive impairment or altered mental status affecting participation\n* Physical conditions signficantly limiting mobility (e.g. severe gait or muscoskeletal disorders)",true,{"count":51,"type":20},700,[23],"The goal of this clinical trial is to learn if cochlear implant activation affects spatial orientation in cochlear implant users. The main question\\[s\\] it aims to answer are\\]:\n\n* Does activation of the cochlear implant improve spatial orientation?\n* Is this improvement caused by better hearing ability through the cochlear implant?\n\nParticipants will:\n\n* Take an online survey including questions about their cochlear implants and clinical questionnaires on dizziness and spatial orientation\n* Undergo balance and spatial orientation tests under different cochlear implant conditions.",[26,55],"Spatial Orientation","NOT_YET_RECRUITING","2026-04-01",{"date":59,"type":32},"2026-04-03",{"date":61,"type":20},"2026-04",{"date":63,"type":20},"2029-12",{"name":65,"class":39},"Insel Gruppe AG, University Hospital Bern",{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":16,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":4,"studyType":78,"phases":4,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":96},"100520011","the-value-electrical-stapedial-reflex-thresholds-esrts-cochlear-implant-mapping-100520011","NCT06051006","The Value Electrical Stapedial Reflex Thresholds (eSRTs) Cochlear Implant Mapping","The Value of Electrical Stapedial Reflex Thresholds (eSRTs) in Determining Upper Stimulation Levels in Cochlear Implant Maps","eSRT","Inclusion Criteria:\n\n* Patients between the ages of 8-17 years at the time of inclusion with cochlear implants for at least 1 year and followed at Hôpital Necker-Enfants malades\n* Use oral French as the main mode of communication\n* Have a tonal threshold with the cochlear implant of 40 dB or more\n* Have a normal tympanogram\n* Have a voice threshold of less than 70% at 30dB HL\n* Information and non-opposition of holders of parental authority and minor patients to participate in the study\n\nExclusion Criteria:\n\n* Present a severe neurological pathology before inclusion (which can be identified by an MRI +\u002F- a neuro-pediatric assessment)\n* Present, on inclusion, a cognitive or psychiatric impairment or severe developmental delay\n* Be part of a family that does not understand oral French\n* Patients under AME (State Medical Aid)","8 Years","17 Years",{"count":77,"type":20},30,"OBSERVATIONAL","One of the most significant challenges in cochlear implant programming, particularly for very young children and those with an associated pathologies, is the measurement of subjective comfort levels (= C-Subjective). Currently, to define this C-Subjective level, patients are presented with a loudness scale and must indicate whether the sound stimulus, sent via the implant, is soft, comfortable, or loud. The lower and upper stimulation levels must be determined for each electrode in order to program the implant. For many patients this can be difficult due to a lack of auditory experience and confusion between the sensation of sound intensity (weak or loud) and frequency (low or high).\n\nA less commonly used but more objective approach to programming upper stimulation levels involves the use of the electrical stapedial reflex threshold (eSRTs) value. eSRTs are a promising measure, given the demonstrated correlation between the threshold that generates a stapedial reflex and the C-subjective level. Furthermore, eSRTs can be recorded in the majority of patients, and can typically be evoked at a comfortable stimulation level i.e. inferior to the uncomfortable level.\n\nThe main objective of this study is investigate the link between subjective comfort levels (C-subjective levels) and the eSRT.",[81,26],"Profound Hearing Loss",[83,84,85,86],"Profound hearing loss","Cochlear implants","Cochlear implant programming","Stapedial reflex","2025-09-05",{"date":89,"type":32},"2025-09-12",{"date":91,"type":32},"2023-12-07",{"date":93,"type":20},"2026-01-07",{"name":95,"class":39},"Assistance Publique - Hôpitaux de Paris",1,{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":101,"acronym":102,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":104,"targetDuration":106,"studyType":78,"phases":4,"briefSummary":107,"conditions":108,"keywords":109,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":122},"100353464","middle-east-med-el-observatory-study-100353464","NCT03882229","Middle East MED-EL Observatory Study","MEMOS","Inclusion Criteria:\n\n* Subjects who are implanted or will be implanted with a MED-EL CI system.\n* Signed written informed consent for data collection for registry purposes.\n\nExclusion Criteria:\n\n* Lack of compliance with any inclusion criteria.\n* Subjects not receiving a MED-EL CI system due to medical or personal reasons after having consented.\n* Anything that, in the opinion of the Investigator would place the subject at increased risk or preclude the subject's full compliance with or completion of the registry procedures.",{"count":105,"type":20},100,"5 Years","In the field of cochlear implant research, there are only few data on long-term observational studies available to gain knowledge on clinical effectiveness. Longitudinal comparisons of data collected in different clinics is challenging due to the heterogeneity in measures and procedure.\n\nThis Registry represents a non-interventional systematic collection of clinical data in which prospective data from children and adults are collected as anonymized data sets, derived from original clinical records on appropriately informed subjects. Each subject will be treated as per clinical routine.\n\nThe Registry will be implemented through a secure, cloud-based, platform that enables collection of anonymized data at consistent time intervals, thus enabling the comparison of repeated measures over time.",[26],[110,111],"Registry","Observational Study","2025-08-18",{"date":114,"type":32},"2025-08-19",{"date":116,"type":32},"2020-02-11",{"date":118,"type":20},"2030-01",{"name":120,"class":121},"MED-EL Elektromedizinische Geräte GesmbH","INDUSTRY",3,{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":127,"acronym":4,"eligibilityCriteria":128,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":129,"targetDuration":4,"studyType":21,"phases":131,"briefSummary":132,"conditions":133,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":96},"100562744","assessing-the-effect-of-computer-based-auditory-training-on-adult-cochlear-implant-speech-and-quality-of-life-outcomes-100562744","NCT06607146","Assessing the Effect of Computer-based Auditory Training on Adult Cochlear Implant Speech and Quality-of-life Outcomes","Inclusion Criteria:\n\n* Adult patients with a diagnosis of bilateral moderate-to-profound sensorineural hearing loss who are undergoing unilateral or simultaneous bilateral cochlear implantation at the Mayo Clinic in Rochester MN.\n\nExclusion Criteria:\n\n* Patients undergoing revision implantation, completion bilateral cochlear implantation, or implantation for unilateral deafness will be excluded from enrollment\n* Patients unable or unwilling to use a computer or similar device will be excluded from enrollment.\n* Patients will be excluded if they speak a language not supported by the Sound Success platform. Sound Success is available in English, Spanish, French, Italian, Dutch, Polish, and Danish.",{"count":130,"type":20},80,[23],"The purpose of this study is to compare the effectiveness of a free computer-based auditory training program, Sound Success (Advanced Bionics, Valencia, CA), with the current standard of care of patient-directed auditory training in improving common measures of speech recognition and cochlear implant (CI) specific quality-of-life in new adult CI recipients in their first year post-activation.",[26,134],"Bilateral Sensorineural Hearing Loss","2025-07-31",{"date":137,"type":32},"2025-08-01",{"date":139,"type":32},"2023-05-09",{"date":141,"type":20},"2026-12-31",{"name":143,"class":39},"Mayo Clinic",{"id":145,"slug":146,"hasResults":11,"nctId":147,"briefTitle":148,"officialTitle":148,"acronym":149,"eligibilityCriteria":150,"healthyVolunteers":49,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":151,"targetDuration":4,"studyType":21,"phases":153,"briefSummary":154,"conditions":155,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":163,"locationsCount":96},"100416902","encoding-temporal-fine-structure-for-cochlear-implants-100416902","NCT04708717","Encoding Temporal Fine Structure for Cochlear Implants","TFS4CIs","Inclusion Criteria:\n\n* Cochlear implant users.\n\nExclusion Criteria:\n\n* Younger than 18 years.",{"count":152,"type":20},24,[23],"The goal of this study is to improve music and speech perception for cochlear implant users. Presently, most cochlear implants discard the temporal fine structure of sound, which is information that is widely believed to contribute to both music and speech perception. The proposed work examines perceptual and physiological changes that occur once this information is provided to cochlear implant users in a clear and consistent manner.",[156,26],"Hearing Loss","2025-06-27",{"date":159,"type":32},"2025-07-02",{"date":161,"type":32},"2020-09-01",{"date":57,"type":20},{"name":164,"class":39},"University of Southern California",{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":172,"targetDuration":4,"studyType":21,"phases":173,"briefSummary":174,"conditions":175,"keywords":177,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":183,"lastUpdatePostDateStruct":184,"startDateStruct":186,"completionDateStruct":188,"leadSponsor":190,"locationsCount":96},"100482168","place-based-cochlear-implant-mapping-100482168","NCT05558514","Place-based Cochlear Implant Mapping","Performance Comparisons With Default Versus Place-based Maps","Inclusion Criteria:\n\n* Adults (18 years of age or older) with moderate-to-profound sensorineural hearing loss bilaterally or single-sided deafness (SSD)\n* Approved by the Cochlear Implant Program at London Health Sciences Centre (LHSC) to undergo unilateral cochlear implantation\n* Identify as a native English speaker (recorded speech recognition\u002Fperception materials are presented in English)\n* Deny any cognitive issues\n* Willing and able to participate in study procedures (e.g., unaided testing, speech recognition testing, spatial hearing testing)\n* Willing and able to return for follow-up visits (same intervals as recommended clinically for routine follow-up)\n\nExclusion Criteria:\n\n* Fail the Mini Mental State Examination based on their age and education level",{"count":77,"type":20},[23],"The current standard of care approach for programming cochlear implants uses a generalized pitch-map for all patients. This approach fails to account for individualized inner ear anatomy. As a result, many cochlear implant recipients experience place-pitch mismatch. We have recently developed an automated mathematical tool to produce patient-specific, customized cochlear implant pitch-maps (Helpard et al., 2021). In this study, cochlear implant recipients will be randomized to receive either the clinical default pitch-map (the control group) or a place-based pitch-map (the intervention group).\n\nAssessments will be conducted at multiple time-intervals to account for patient acclimation and plasticity to both the generalized and individualized pitch-maps. Audiological assessments will be tuned to identify patients' ability to discern pitch scaling and variation in sounds, as well as to understand complexities in speech such as mood and tone. Audiological testing will be conducted in collaboration with the National Centre for Audiology (London, ON) to ensure that the most accurate and relevant metrics are applied.",[176,26],"Hearing Loss, Sensorineural",[178,179,180,181,182],"cochlear implant","pitch map","hearing loss","cochlear implant programming","place-pitch mismatch","2025-03-24",{"date":185,"type":32},"2025-03-28",{"date":187,"type":32},"2023-06-07",{"date":189,"type":20},"2026-05",{"name":191,"class":39},"Western University, Canada",{"id":193,"slug":194,"hasResults":11,"nctId":195,"briefTitle":196,"officialTitle":196,"acronym":197,"eligibilityCriteria":198,"healthyVolunteers":49,"sex":16,"minAge":106,"maxAge":199,"enrollmentInfo":200,"targetDuration":4,"studyType":21,"phases":202,"briefSummary":203,"conditions":204,"keywords":205,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":211,"startDateStruct":213,"completionDateStruct":215,"leadSponsor":217,"locationsCount":96},"100340067","pitch-perception-and-memory-deficits-and-training-100340067","NCT03707691","Pitch Perception and Memory: Deficits and Training","Pitch_Train","Inclusion Criteria:\n\nFor adult participants:\n\n* Aged between 18 and 90\n* Absence of neurological and psychiatric disorders\n* No major cognitive deficit, ability to understand and apply study instructions\n* Motivation to participate efficiently in the study\n* Written informed consent to participant in the study\n* Affiliated to social security\n* Control participants and participants with congenital amusia for Experiment 5: MRI\u002FMEG compatibility\n\nFor underage participants:\n\n* Subject aged 5 years and over\n* Informed consent of parents or guardians for the participation of the child being studied\n* No neurological or psychiatric history\n* Without major cognitive impairment and ability to understand and apply setpoint.\n* Subject affiliated to a social security scheme\n* Motivation to participate effectively in the project\n\nExclusion Criteria:\n\nFor adult participants:\n\n* Age below 18 or above 90\n* Pregnant or breast-feeding woman\n\nFor underage participants:\n\n\\- Pregnant or nursing minors","90 Years",{"count":201,"type":20},960,[23],"Pitch perception and memory are central in auditory cognition, in particular for sound source segregation and recognition, speech prosody and music processing. Here the investigator assess pitch perception and memory in hearing-impaired listeners wearing cochlear implant(s) and listeners with congenital amusia, both compared with control listeners. Behavioral, EEG, and MEG measures are collected in audio and audio-visual contexts to characterize pitch processing deficits, and test a pitch training program.",[26],[206,26,207,208,209],"Hearing","Congenital Amusia","Pitch","Audio-visual interactions","2025-02-27",{"date":212,"type":32},"2025-03-03",{"date":214,"type":32},"2019-11-26",{"date":216,"type":20},"2027-10-26",{"name":218,"class":39},"Hospices Civils de Lyon",{"id":220,"slug":221,"hasResults":11,"nctId":222,"briefTitle":223,"officialTitle":224,"acronym":225,"eligibilityCriteria":226,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":227,"targetDuration":4,"studyType":21,"phases":229,"briefSummary":230,"conditions":231,"keywords":232,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":239,"lastUpdatePostDateStruct":240,"startDateStruct":242,"completionDateStruct":244,"leadSponsor":246,"locationsCount":96},"100550919","clinical-trial-to-compare-two-surgical-approaches-to-the-cochlea-100550919","NCT06453343","Clinical Trial to Compare Two Surgical Approaches to the Cochlea","Multicenter Randomized Controlled Trial Comparing Surgical Approaches to the Cochlea for the Slim Modiolar Electrode: Assessing Intracochlear Trauma Using Intraoperative Electrocochleography Measurements and Preservation of Residual Hearing","BULLS-I","Inclusion Criteria:\n\n* Individuals aged 18 years and older who have clinically established post-linguistic sensorineural hearing loss.\n* CI candidate based on local or national reimbursement criteria.\n* Cochlear implantation with a CI632.\n* Preoperative 500 Hz pure-tone air conduction threshold \\\u003C80 dB hearing level (HL) in the ear to be implanted.\n* Willing and able to provide written informed consent.\n\nExclusion Criteria:\n\n* Previous or existing CI recipient.\n* Ossification or other anatomical abnormalities of the cochlea or its windows possibly affecting normal electrode array insertion.\n* Abnormal cochlear nerve anatomy on preoperative CT or MRI.\n* Subjects who are unable to undergo CT or MRI.\n* Deafness due to acoustic nerve or central auditory pathway lesions.\n* Diagnosis of auditory neuropathy.\n* Active middle ear infection.\n* Additional handicaps that would prevent participation in study evaluations.\n* Unrealistic expectations from the participant regarding the possible benefits, risks, and limitations inherent to the CI procedure and the investigation.\n* Cochlear employees or employees of Contract Research Organisations or contractors engaged by Cochlear for the purposes of this investigation.",{"count":228,"type":20},50,[23],"This is a prospective multicenter multinational randomized control trial. The duration of the study for the individual patient will be approximately 1 year (pre-operative assessments, 1 week, 3 months and 12 months follow-up assessments). Participants will be randomized to one of two surgical approaches: eRW or CO, with a 1:1 allocation in a parallel design.",[26,176],[233,234,235,236,237,238],"Surgical approach","Round Window","Cochleostomy","Electrocochleography","Imaging","Residual hearing preservation","2025-02-21",{"date":241,"type":32},"2025-02-25",{"date":243,"type":32},"2025-01-01",{"date":245,"type":20},"2027-11",{"name":247,"class":39},"Radboud University Medical Center",{"id":249,"slug":250,"hasResults":11,"nctId":251,"briefTitle":252,"officialTitle":253,"acronym":4,"eligibilityCriteria":254,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":255,"targetDuration":4,"studyType":21,"phases":257,"briefSummary":258,"conditions":259,"keywords":261,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":265,"lastUpdatePostDateStruct":266,"startDateStruct":268,"completionDateStruct":270,"leadSponsor":272,"locationsCount":96},"100544929","investigation-of-a-device-to-deliver-intra-operative-therapeutic-hypothermia-for-hearing-preservation-in-cochlear-implantation-100544929","NCT06375278","Investigation of a Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation","Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation","Inclusion Criteria:\n\nPotential participants for the study are patients who have been diagnosed with severe to profound hearing loss (HL) and plan to undergo cochlear implantation (CI) at the University of Miami. The cochlear implant surgery, pre and post-surgical care, and activation and programming of the implant are part of the participants' standard of care. If the inclusion criteria are met (age 18 years and older, equal number of men and women, profound sensorineural hearing loss (for safety study n=6) and residual hearing (see criteria below) from pre-surgical auditory brainstem response (ABR) (for efficacy study n=48), equal numbers of CI devices from all 3 manufactures and English or Spanish speakers the patient will be approached by the study personnel and will be asked to participate in the study.\n\nExclusion Criteria:\n\nSubjects under 18 years of age. Subjects not meeting functional hearing requirements.\n\nTypes of CI devices:\n\nThe study will enroll patients receiving CI devices from all three manufactures.\n\n1. Advanced Bionics (FDA indications - severe to profound sensorineural hearing loss (greater than or equal to 70 dB HL)\n\n   1. HiRes Ultra 3D slim J\n   2. HiRes Ultra 3D midScala\n2. Cochlear Corporation (FDA indications - moderate to profound sensorineural hearing loss; sentence recognition less than or equal to 50% in the ear to be implanted AND less than or equal to 60% in the contralateral ear\n\n   1. CI632\n   2. CI622\n   3. CI612\n3. Med-EL (moderately-severe to severe sensorineural hearing loss (greater than or equal to 65 db HL).\n\n   1. Synchrony 2 Flex soft\n   2. Synchrony 2 Flex28\n   3. Synchrony 2 Flex 24\n   4. Synchrony 2 Compressed\n   5. Synchrony 2 Medium\n\nAdditional patients receiving devices not listed here may be eligible as the criteria by manufacturer change.",{"count":256,"type":20},54,[23],"The goal of this interventional clinical study is to investigate the use of mild therapeutic hypothermia for preservation of residual hearing in cochlear implant surgery. The main questions the trial aims to answer are:\n\n1. Is mild therapeutic hypothermia safe for use during cochlear implantation?\n2. Is mild therapeutic hypothermia effective at preserving residual hearing after cochlear implantation?\n\nParticipants will receive mild therapeutic hypothermia therapy during cochlear implant surgery. Researchers will compare results from those receiving the therapy to those from a control group (individuals receiving no therapy).",[26,260,156],"Cochlear Implantation",[262,263,264],"Cochlear Implant","Residual Hearing","Hearing Preservation","2024-11-18",{"date":267,"type":32},"2024-11-21",{"date":269,"type":32},"2024-09-23",{"date":271,"type":20},"2026-07-31",{"name":273,"class":121},"Restorear Devices LLC"]