[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cognitive-abilities\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cognitive-abilities":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,48,75,100,133],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100624268","eeg-guided-binaural-beat-audio-to-reduce-performance-related-stress-and-improve-cognition-100624268",false,"NCT07407426","EEG-Guided Binaural Beat Audio to Reduce Performance-Related Stress and Improve Cognition","Effects of EEG-guided Binaural Beat Audio Intervention on Brain Reactivity Associated With Performance-related Stress and Cognition Among Professional Musicians: A Randomized, Double-blinded, Sham-controlled Functional Neuroimaging Trial","Inclusion Criteria:\n\n* Adults (18+ years) enrolled as undergraduate music majors at Texas Tech University\n* Currently preparing for an upcoming concert performance within the next 3 months\n* Able to read standard musical notation\n\nExclusion Criteria:\n\n* Subjects with contraindications to undergo MRI after being screened by the TTNI safety screening sheet - specifically, Subjects with implanted devices that are not compatible with MRI including, but not limited to cardiac pacemakers, cardiac defibrillators, aneurysm clips, carotid artery vascular clamps, implanted nerve stimulators (neuron-stimulators also called TENS or wires), bone growth or bone fusion stimulators, cochlear implants, vagus nerve stimulators, filters for blood clots (Umbrella, Greenfield, bird's nest), embolization coils (e.g. Gianturco) in the brain, ocular implants, vascular stents, medication pumps, medication patches delivering medications, implanted limbs, ventricular shunts, metal joints, rods, plates, pins, screws, nails, or clips, penile implants, or contraceptives devices including IUDs, cervical pessaries and diaphragms Subjects who have undergone cataract surgery Subjects who have shrapnel or metal in the head, eyes or skin Subjects with a history of working with metal fragments ( or have had metal removed from eyes Subjects with gunshot wounds or BB gun injury Subjects with permanent metal body piercings or jewelry that cannot be removed Subjects who use hearing aids or have braces \u002F permanent retainers that cannot be removed temporarily for the MRI scans Subjects with large tattoos in the head and neck area Subjects with claustrophobia Subjects who are currently pregnant or suspected to be pregnant\n* Physical, medical, neurological or psychiatric impairments (including substance abuse)\n* Current use of medications that could affect cognitive performance (including beta-blockers, stimulants, anxiolytics, antidepressants, or antipsychotics)\n* History of head injury resulting in loss of consciousness\u002Fhistory of brain surgery\n* History of diagnosed hearing impairment or use of hearing aids\n* Current or past diagnosis of epilepsy or seizure disorders\n* Unwillingness or inability to refrain from alcohol consumption 48 hours prior to the study visit\n* Unwillingness or inability to refrain from caffeine consumption 12 hours prior to the study visit\n* Current\u002Fpast history of substance abuse\n* Pregnancy or possibility of pregnancy\n* Unwillingness or inability to follow written, on-screen, and verbal instructions given by the study team",true,"ALL","18 Years",{"count":20,"type":21},32,"ESTIMATED","INTERVENTIONAL",[24],"NA","Performance-related stress can impair sustained attention, inhibitory control, and memory. This randomized, double-blinded, sham-controlled parallel-arm trial evaluates whether a 30-minute EEG-guided binaural beat audio intervention reduces subjective stress\u002Fperformance anxiety and improves cognition, and whether it changes task-related brain reactivity measured by fMRI. The intervention uses real-time single-electrode EEG recorded over the left prefrontal cortex to dynamically adjust binaural beat frequencies to guide the brain toward a target state; the sham condition uses non-binaural music delivered through identical headphones.\n\nAdult music majors preparing for an upcoming concert will complete pre- and post-intervention fMRI sessions during cognitive\u002Fmusic tasks (Stop Signal Reaction Task, Music Reading Task, Music Memory Retrieval Task) and complete visual analog scales (VAS) assessing performance anxiety, stress, and related subjective states. The primary outcomes include fMRI task-related activity in stress-regulation regions (dlPFC, amygdala, hippocampus), behavioral inhibition indices from the stop-signal task, music memory retrieval accuracy, and VAS-reported stress\u002Fperformance anxiety.",[27,28,29,30],"Cognitive Abilities","Performance","Stress","Cognitive Performance",[32,33,34],"neurofeedback","cognitive performance","stress","NOT_YET_RECRUITING","2026-04-06",{"date":38,"type":39},"2026-04-13","ACTUAL",{"date":41,"type":21},"2026-04-07",{"date":43,"type":21},"2026-08-30",{"name":45,"class":46},"Texas Tech University Health Sciences Center","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100627240","telerehab-exerbrain-bridging-physical-and-cognitive-therapy-in-stroke-100627240","NCT07446062","Telerehab Exerbrain: Bridging Physical and Cognitive Therapy in Stroke","Effects of Web-Based Physical-Cognitive Telerehabilitation Exergaming on Physical and Cognitive Performance in Chronic Stroke Survivors: Protocol for a Randomized Controlled Trial","Inclusion Criteria:\n\n* diagnosed with ischemic or hemorrhagic stroke at least 6 months before enrollment\n* aged between 20 and 80 years\n* able to walk at least 10 meters with or without assistive devices\n* able to perform sit-to-stand safely with or without assistive devices\n* can see the screen of a tablet or notebook computer at a distance of at least 60 cm\n* have a stable medical condition and can follow study instructions\n* frequent users of a mobile phone, tablet, or notebook computers\n\nExclusion Criteria:\n\n* have medical conditions or complications that would be unsafe to exercise\n* have neglect, impaired communication, or uncorrected visual problems \\[30\\], or - have severe spasticity of the upper or lower extremities (Modified Ashworth Scale ≥ 3)","20 Years","80 Years",{"count":58,"type":21},52,[24],"The goal of this clinical trial is to learn if a web-based exercise and cognitive training (physical-cognitive) program works to improve movements and brain function in adults with long-term stroke. It will also learn whether the program is safe and enjoyable.\n\nThe main questions it aims to answer are:\n\nDoes the program improve walking, balance, strength, and reduce fall risk? Does the program improve cognitive skills such as memory, attention, and problem-solving? Researchers will compare the online exercise-and-cognitive training program to usual care to see if the program leads to greater improvements.\n\nParticipants will:\n\n* Be randomly assigned to either the online training group or the usual care group\n* If in the training group, complete the home-based program for 12 weeks.\n* Take part in physical and cognitive tests before and after the program",[62,63,64,65,27],"Stroke","Tele-rehabilitation","Exercise","Motor Abilities","2026-02-25",{"date":68,"type":39},"2026-03-03",{"date":70,"type":21},"2026-02",{"date":72,"type":21},"2027-03",{"name":74,"class":46},"Chiang Mai University",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":16,"sex":17,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":90,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":47},"100608982","effect-of-instrument-assisted-soft-tissue-mobilization-on-functional-and-cognitive-abilities-in-elderly-100608982","NCT07208630","Effect of Instrument-assisted Soft Tissue Mobilization on Functional and Cognitive Abilities in Elderly","IASTM-AGE","Inclusion Criteria:\n\n* 60 elderly subjects aged range from 65-75 years old will participant in the study from both genders.\n* had cognitive abilities to understand explanations and instructions\n* did not take any medication that can affect their balance.\n\nExclusion Criteria:\n\n* They neither had sever musculoskeletal disorders\n* Nor neurological damage related to balance (dizziness, vestibular dysfunction)\n* Nor orthostatic hypotension\n* Nor health risk factors.","65 Years","75 Years",{"count":85,"type":21},60,[24],"PURPOSE: To determine the effect of Instrument-assisted soft tissue mobilization on functional and cognitive abilities in elderly.\n\nBACKGROUND: There is an increased interest in health care with growth of the older population.\n\nInstrument-Assisted Soft Tissue Mobilization (IASTM) is a manual therapy technique using specially designed tools to apply pressure and mobilize soft tissues. It has gained attention as a non-invasive intervention that can aid in improving musculoskeletal health and overall function, especially in older adults. Given the aging population and the rise in age-related functional and cognitive decline, there is a pressing need for effective strategies to enhance quality of life in this demographic.\n\nIn the elderly, musculoskeletal issues, such as reduced muscle flexibility, joint stiffness, and soft tissue restrictions, are common and can severely impact physical function. IASTM has been shown to increase tissue perfusion, reduce fascial restrictions, and improve joint mobility. These effects are critical in countering age-related declines in mobility, balance, and overall physical functionality, ultimately promoting greater independence and reducing fall risk. Improved physical function through IASTM may also influence cognitive health positively, as increased physical activity and mobility are linked to better cognitive outcomes in the elderly.\n\nHYPOTHESES: There will be no significant effect of Instrument-assisted soft tissue mobilization on functional and cognitive abilities in elderly.\n\nRESEARCH QUESTION: Does instrument-assisted soft tissue mobilization is effective on functional and cognitive abilities in elderly?",[89,27],"Functional Abilities","RECRUITING","2026-02-21",{"date":93,"type":39},"2026-02-24",{"date":95,"type":39},"2025-10-03",{"date":97,"type":21},"2026-03",{"name":99,"class":46},"Cairo University",{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":16,"sex":17,"minAge":107,"maxAge":108,"enrollmentInfo":109,"targetDuration":4,"studyType":22,"phases":111,"briefSummary":112,"conditions":113,"keywords":119,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":124,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":4},"100622884","school-meals-in-denmark-100622884","NCT07389421","School Meals in Denmark","School Meals in Denmark: Evaluation of a National School Meal Pilot Program on Children's Health, Learning and Well-being - a Natural Experiment","Inclusion Criteria:\n\n* All children attending 3rd, 4th or 7th grade in the recruited schools\n\nExclusion Criteria:\n\n* No exclusion criteria will be applied","9 Years","14 Years",{"count":110,"type":21},3200,[24],"This study looks at how a national school meal program affects the health, well-being, and learning of Danish schoolchildren aged 10 to 15 years.\n\nThe study is part of the Danish National School Meal Pilot Program (2025-2028), which provides free school meals at selected public schools. Some school classes receive free school meals, while other classes do not and are used for comparison.\n\nChildren are followed for about 1.5 years. Information is collected before and after the program using simple health measurements, questionnaires about well-being, and age-appropriate cognitive tests.\n\nThe study also uses information from Danish national registers to better understand the children's background and to study longer-term outcomes related to health, education, and social conditions. In addition, the study examines whether school meal programs are cost-effective by comparing their costs with potential benefits for children and society.\n\nThe goal of the study is to find out whether free school meals can improve children's health, well-being, and learning, and help reduce social differences.",[114,115,116,117,27,118],"Childhood Obesity","Childhood Obesity Pevention","Well-being\u002FQuality of Life","Diet Habits","Healthy",[120,121,122,123],"physical health","well-being","learning","diet","2026-01-28",{"date":126,"type":39},"2026-02-05",{"date":128,"type":21},"2026-02-11",{"date":130,"type":21},"2029-12-31",{"name":132,"class":46},"University of Copenhagen",{"id":134,"slug":135,"hasResults":11,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":4,"eligibilityCriteria":139,"healthyVolunteers":11,"sex":17,"minAge":82,"maxAge":4,"enrollmentInfo":140,"targetDuration":4,"studyType":22,"phases":142,"briefSummary":143,"conditions":144,"keywords":148,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":4},"100599285","effects-of-exercise-cognitive-training-and-their-combination-in-institutionalized-older-adults-100599285","NCT07082504","Effects of Exercise, Cognitive Training, and Their Combination in Institutionalized Older Adults","Effects of Physical Exercise Programs, Cognitive Stimulation, and Their Combination on Mobility, Cognitive Function, and Psychosocial Well-Being in Institutionalized Older Adults","Inclusion Criteria:\n\n* Individuals of both sexes.\n* Age 65 years or older.\n* Retired.\n* Institutionalized for more than three months.\n* Provide informed consent and agree to participate.\n\nExclusion Criteria:\n\n* Lack of cooperation or cognitive capacity to participate.\n* Diagnosis of dementia or Alzheimer's disease.\n* Presence of acute medical conditions.\n* Physical or cognitive impairments that prevent completion of study procedures.",{"count":141,"type":21},140,[24],"The goal of this clinical trial is to learn if physical exercise, cognitive stimulation, or a combination of both can improve mobility, cognitive function, and psychosocial well-being in institutionalized older adults aged 65 and older. The main questions it aims to answer are:\n\n* Does physical exercise improve strength, flexibility, balance, and mobility?\n* Does cognitive stimulation improve executive function and mental state?\n* Does combining both interventions provide greater benefits than either intervention alone?\n\nResearchers will compare the physical exercise group, the cognitive stimulation group, and the combined group to a control group that receives no active intervention to see which approach leads to the most improvement.\n\nParticipants will:\n\n* Take part in either physical exercise, cognitive stimulation, or both, 3 times per week for 12 weeks\n* Complete assessments before the intervention, after 12 weeks, and again after 6 months\n* Answer questionnaires and perform physical and cognitive tests to measure changes in health and well-being",[145,146,27,147,116],"Aging","Institutionalized Older Adults","Mobility and Independence",[149,150,151,152,153,154,155],"Physical Exercise","Cognitive Stimulation","Executive Function","Quality of Life","Elderly Adults","Physical Function","Dual-Task Training","2025-07-15",{"date":158,"type":39},"2025-07-24",{"date":160,"type":21},"2025-09-01",{"date":162,"type":21},"2026-05-30",{"name":164,"class":46},"University of Salamanca"]