[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"cognitive-reserve\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:cognitive-reserve":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100643936","cognitive-reserve-and-post-fatigue-recovery-in-older-adults-100643936",false,"NCT07667985","Cognitive Reserve and Post-Fatigue Recovery in Older Adults","Determining the Post-Physical and Mental Fatigue Recovery Perspectives of Older Adults Based on Their Cognitive Reserves","Inclusion Criteria:\n\n* being 65 years of age or older,\n* not having any neurological, psychiatric, or systemic disease that would affect one's mental state, and not using any medication for these conditions.\n\nExclusion Criteria:\n\n* Being younger than 65 years old,\n* having an illness or taking medication that affects mental health, or being\n* unable to complete the questionnaires.",true,"ALL","65 Years","90 Years",{"count":21,"type":22},400,"ESTIMATED","OBSERVATIONAL","As people grow older, it is common to experience a drop in physical stamina and memory functions. This can make recovering from daily physical and mental fatigue more difficult, which directly impacts an individual's independent daily life and overall quality of life.\n\n\"Cognitive reserve\" is a term that describes the brain's built-in resilience. Built over a lifetime through education, work, and social activities, a higher cognitive reserve acts like a buffer, helping the brain adapt to stress and aging. While research shows that a high cognitive reserve protects against conditions like dementia, we still do not fully understand how it helps older adults bounce back from normal, everyday physical and mental exhaustion.\n\nThe goal of this study is to investigate how cognitive reserve levels influence how individuals aged 65 and older perceive their recovery after experiencing physical and mental fatigue.\n\nWhat the Study Involves\n\nThe researchers will evaluate participants aged 65 and older to measure their baseline cognitive reserve levels. The study will look closely at how these levels affect the participants':\n\nAbility to cope with daily physical and mental fatigue. Need for rest and rest patterns. Time and ability to return to normal daily activities. Overall perception of their mental and physical recovery. Expected Outcome By understanding this relationship, the study aims to fill a gap in medical literature and help healthcare providers design better, more personalized rehabilitation and lifestyle support programs to improve the quality of life for older adults.",[26,27,28,29,30],"Cognitive Reserve","Aging","Mental Fatigue","Fatigue","Recovery of Function",[32,33,34,35],"aging","cognitive reserve","fatigue","Post-Fatigue Recovery","RECRUITING","2026-06-19",{"date":39,"type":40},"2026-06-25","ACTUAL",{"date":42,"type":40},"2026-06-20",{"date":44,"type":22},"2026-09-22",{"name":46,"class":47},"Uşak University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":16,"sex":17,"minAge":56,"maxAge":19,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":62,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":4},"100553784","use-of-sevoflurane-to-test-concept-of-cognitive-reserve-100553784","NCT06490588","Use of Sevoflurane to Test Concept of Cognitive Reserve","The Use of Sevoflurane to Test the Concept of Intra-individual Variability in Bispectral Index Monitor and Cognitive Reserve by Examining Time to Emergence and Recovery","Inclusion Criteria:\n\n* \\- Minimal completion of high-school education\n* Adult patient \\\u003C 85 years of age\n* No prior known history of cognitive\u002Fbrain disease\n* ASA class I-II\n* Undergoing general anesthesia with sevoflurane for maintenance anesthesia\n* Same-day surgery\n* Elective procedures\n* No prior history of cardiac disease\n\nExclusion Criteria:\n\n* \\- History of chronic pain\n* Perioperative use of anesthetic agents other than propofol, fentanyl, dilaudid, and sevoflurane\n* History of alcohol\u002Fsubstance druge abuse\n* Psychiatric history\n* Morbid history\n* History of OSA, stroke, or TIA\n* Blindness\n* Deafness","18 Years",{"count":58,"type":22},70,"Previous pilot study had demonstrated a correlation between cognitive reserve and BIS variability during steady state of anesthesia. This study, we intend to evaluate the association between BIS variability and emergence and recovery time from anesthesia.",[26,61],"BIS","NOT_YET_RECRUITING","2024-06-28",{"date":65,"type":40},"2024-07-08",{"date":67,"type":22},"2024-09",{"date":69,"type":22},"2026-09",{"name":71,"class":47},"Los Angeles General Medical Center"]