[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"colo-rectal-polyps\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:colo-rectal-polyps":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100643756","phase-4-patient-controlled-propofol-sedation-versus-standard-sedation-in-advanced-therapeutic-colonoscopy-with-a-focus-on-patient-satisfaction-100643756",false,"NCT07637279","Patient Controlled Propofol Sedation Versus Standard Sedation in Advanced Therapeutic Colonoscopy With a Focus on Patient Satisfaction","Patient-Controlled Anesthesia for Endoscopic Procedural Sedation (PCAPS). A Randomized Controlled Trial Evaluating Patient-controlled Propofol Sedation in Therapeutic Colonoscopies","PCAPS2","Inclusion Criteria:\n\n* Scheduled for elective diagnostic colonoscopy in propofol sedation\n* Able to understand the study information and provide inform consent\n* ASA I-II\n* Able to understand and use the patient-controlled sedation device\n* Able to complete study questioneeres\n\nExclusion Criteria:\n\n* ASA \\>=III\n* Known hypersensitivity or contraindication to propofol or any excipient in the formulation.\n* Pregnancy or breastfeeding.\n* Inability to provide valid informed consent\n* Cognitive impairment, severe psychiatric illness, or other condition limiting reliable participation or questionnaire completion.\n* Inability to understand study procedures or insufficient language proficiency without available validated study support.\n* History of serious adverse reaction or complication related to sedation or anesthesia.","ALL","18 Years","90 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"PHASE4","The goal of this clinical trial is to learn if patient administered propofol sedation results in superior patient satisfaction compared to standard conscious sedation in advanced therapeutic endoscopy.\n\n• Does self administration of the sedative propofol increase patient satisfaction? Researchers will compare patient administered propofol sedation (where the patient administers propofol by pushing a button) with standard conscious sedation\n\nParticipants will:\n\n* Be randomized to either sedation route.\n* Answer a preendoscopy questioneere and a postendoscopy questioneere 1 hour after the examination as well as one week after the examination.",[28],"Colo-rectal Polyps",[30,31,32],"Colonoscopy","Endoscopic submucosal dissection","Patient satisfaction","NOT_YET_RECRUITING","2026-06-07",{"date":36,"type":37},"2026-06-09","ACTUAL",{"date":39,"type":22},"2026-11-01",{"date":41,"type":22},"2028-11-01",{"name":43,"class":44},"Karolinska Institutet","OTHER",{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":51,"targetDuration":4,"studyType":23,"phases":53,"briefSummary":55,"conditions":56,"keywords":57,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":4},"100639002","comparison-of-the-diagnostic-accuracy-between-three-dimensional-and-standard-colonoscopy-of-colorectal-polyps-100639002","NCT07619248","Comparison of the Diagnostic Accuracy Between Three Dimensional and Standard Colonoscopy of Colorectal Polyps","Inclusion Criteria:\n\n* Patients aged 18 years or older.\n* Patients who meet the indications for undergoing colonoscopy.\n\nExclusion Criteria:\n\n* Patients younger than 18 years of age or those with contraindications precluding them from undergoing a colonoscopy.\n\n(Contraindications for colonoscopy: patients with a recent history of myocardial infarction, pulmonary embolism, cerebrovascular infarction, severe unstable cardiovascular disease, acute abdominal inflammation combined with peritonitis, fulminant colitis, acute diverticulitis, colonic perforation, or toxic megacolon).\n\n* Patients with familial hereditary colorectal cancer or colonic polyposis syndromes.\n* Patients with inflammatory bowel disease (IBD).\n* Subjects who are unable to complete the colonoscopy or those with poor bowel preparation.\n* Subjects who are unable to confirm the date of their previous colonoscopy.",{"count":52,"type":22},600,[54],"NA","Colorectal cancer (CRC) is one of the most common cancers worldwide. These malignancies originate in the colon or rectum, and the majority evolve from pre-existing colonic adenomas (a type of colon polyp). Early detection, identification, and removal of these precancerous lesions can effectively reduce the morbidity and mortality of colorectal cancer.\n\nHowever, not all colonic polyps possess a significant risk of malignant transformation. Polyps can generally be subdivided into \"neoplastic\" and \"non-neoplastic\" lesions; major non-neoplastic polyps include inflammatory polyps, hamartomas, lymphoid polyps, mucosal prolapse polyps, and hyperplastic polyps. On the other hand, neoplastic polyps have the potential to develop into malignancies, primarily including adenomatous polyps and serrated polyps. Adenomatous polyps account for more than 50% of all colonic polyps and are the most common precancerous lesions for CRC. Clinically, they can be further classified into tubular, tubulovillous, or villous adenomas based on histological subtypes. As for serrated polyps, traditional serrated adenomas (TSAs) and sessile serrated lesions (SSLs) possess carcinogenic potential.\n\nDuring a colonoscopy, detecting colonic polyps is crucial, but it is equally important to identify which polyps have malignant potential. This allows for the accurate resection of true precancerous lesions while avoiding the procedural risks associated with unnecessary polypectomies. Furthermore, in rare instances, diminutive polyps may harbor cancer with deep submucosal invasion. Due to the risks of incomplete resection and lymph node metastasis, such lesions are not suitable for endoscopic resection. Therefore, achieving an accurate endoscopic diagnosis is a key step in determining the most appropriate management strategy for colonic polyps.\n\nTo improve the diagnostic accuracy of endoscopy for colonic polyps, multiple modalities have been developed, including careful observation of lesion morphology, as well as various image-enhanced technologies and chromoendoscopy. Meanwhile, three-dimensional (3D) endoscopy, a novel technology, offers superior spatial resolution and depth perception compared to conventional two-dimensional (2D) endoscopy. Studies have confirmed that 3D endoscopy can improve the adenoma detection rate (ADR) due to its enhanced ability to detect flat and inconspicuous lesions. However, whether 3D colonoscopy can also enhance the endoscopic diagnostic accuracy for colonic polyps remains to be explored. Therefore, we designed a randomized controlled trial (RCT) to investigate whether 3D colonoscopy can improve the diagnostic accuracy of colonic polyps compared to conventional 2D colonoscopy.",[28,30],[58,30,59,60],"Endoscopy","Colo-rectal polyps","3D Endoscopy","2026-05-28",{"date":63,"type":37},"2026-06-01",{"date":65,"type":22},"2026-05-12",{"date":67,"type":22},"2027-05-12",{"name":69,"class":44},"National Taiwan University Hospital"]