[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"colon-adenomas\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:colon-adenomas":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100616679","impact-of-computer-aided-detection-system-on-the-proximal-adenoma-miss-rate-100616679",false,"NCT07308743","Impact of Computer-aided Detection System on the Proximal Adenoma Miss Rate","Impact of Computer-aided Detection System on the Proximal Adenoma Miss Rate: a Multicenter Tandem Rondomized Controlled Trial","Inclusion Criteria:\n\n1. Patients age 40-75 years old, regardless of gender\n2. Patients presenting for physical examination, colorectal cancer screening or diagnosis\n3. Patients voluntarily signs an informed consent form\n\nExclusion Criteria:\n\n1. Unable to cooperate ot tolerate colonoscopy\n2. History of inflammatory bowel disease\n3. History of colorectal cancer\n4. Previous colorectal surgery\n5. History of recurrent constipation\n6. Taking anticoagulant and antiplatelet drugs berfore procedure\n7. High risk conditions such as severe cardiovascular and cerebrovascular diseases, severe anemia, or uncorrected infections\n8. Pregnant or lactating women Researchers concluded that patient was not suitable to participate in this trial.",true,"ALL","40 Years","75 Years",{"count":21,"type":22},686,"ESTIMATED","INTERVENTIONAL",[25],"NA","This is a prospective, multicenter randomized controlled trial designed to determine whether the use of computer-aided detection system could reduce the miss rates of adenomas, SSLs, and polyps in the proximal colon during tandem colonoscopy.",[28,29,30],"Colon Adenomas","Colon Polyps","Sessile Serrated Lesion",[32,33,34],"computer-aided detection","proximal adenoma miss rate","Randomized Tandem Colonoscopy Study","NOT_YET_RECRUITING","2025-12-17",{"date":38,"type":39},"2025-12-30","ACTUAL",{"date":41,"type":22},"2025-12",{"date":43,"type":22},"2027-07",{"name":45,"class":46},"Nanfang Hospital, Southern Medical University","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":23,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100602742","computer-aided-water-exchange-colonoscopy-with-and-without-linked-color-imaging-for-detection-of-clinically-significant-serrated-lesions-100602742","NCT07127471","Computer-Aided Water Exchange Colonoscopy With and Without Linked-Color Imaging for Detection of Clinically Significant Serrated Lesions","A Multicenter Prospective Randomized Controlled Trial of Linked-Color Imaging for Detection of Clinically Significant Serrated Lesions in Computer-Aided Water Exchange Colonoscopy","Inclusion Criteria:\n\n* Male and female patients aged 40-80 years scheduled for average-risk screening colonoscopy, post-polypectomy surveillance, diagnosis for gastrointestinal symptoms (including unexplained iron deficiency anemia and clinically significant diarrhea of unexplained origin), or referred for colonoscopy owing to a positive fecal immunochemical test (FIT) or guaiac fecal occult blood test (gFOBT) result.\n\nExclusion Criteria:\n\n* familial adenomatous polyposis and hereditary non-polyposis CRC syndrome\n* personal history of serrated polyposis syndrome\n* personal history of CRC\n* history of inflammatory bowel disease\n* previous colonic resection\n* overt gastrointestinal bleeding\n* emergency colonoscopy or inpatients\n* planned EMR or ESD of large polyps\n* colon stricture or obstruction\n* contraindications to colonoscopy (eg, acute diverticulitis or toxic megacolon)\n* antithrombotic therapy precluding complete polyp resection\n* American Society of Anesthesiology classification of physical status \\>3\n* pregnant women or women planning pregnancy\n* refusal to provide a written informed consent","80 Years",{"count":57,"type":22},1090,[25],"The goal of this clinical trial is to compare the detection rate of clinically significant serrated lesions (CSSL) in participants undergoing water exchange (WE) colonoscopy with artificial intelligence (AI)-based computer-aided detection (CADe) for screening, surveillance, diagnosis for symptoms, or referred owing to a positive fecal immunochemical test (FIT) or guaiac fecal occult blood test (gFOBT) result. There will be two arms in this study: WE with AI-assisted CADe (WEAID) control and WEAID plus linked-color imaging (LCI). The main question it aims to answer is whether the addition of LCI into WEAID colonoscopy increases CSSL detection rate. Both groups use water instead of air to insert the colonoscope into the cecum. The control method uses CADe to help detect colonic lesions. The study method uses a combination of CADe and LCI to detect lesions. Researchers will compare CSSL detection rate to see if the addition of LCI increases the detection of CSSL during CADe-assisted WE colonoscopy.",[61,62,30,28],"Sessile Colonic Polyp","Serrated Lesion","RECRUITING","2025-11-17",{"date":66,"type":39},"2025-11-20",{"date":64,"type":39},{"date":69,"type":22},"2027-07-31",{"name":71,"class":46},"Evergreen General Hospital, Taiwan",4]