[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"colon-neoplasia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:colon-neoplasia":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100590044","magnetic-guided-counetrtraction-during-endoscopic-submucosal-dissection-100590044",false,"NCT06962293","Magnetic Guided Counetrtraction During Endoscopic Submucosal Dissection","Magnetic Anchor Guided - Endoscopic Submucosal Dissection (MAG-ESD) for Gastric and Colorectal Superficial Lesions - a Pilot Study","Inclusion Criteria:\n\n* Patient with superficial gastric or colorectal lesions, scheduled for endoscopic submucosal dissection (ESD).\n\nExclusion Criteria:\n\n1. Patient who refused to participate\n2. Other cases deemed by the examining physician as unsuitable for safe treatment\n\n   The robotic magnetic countertraction system consist of a strong permanent magnet which always have a strong magnetic field in its surrounding. Therefore, we follow the MRI precautions for the strict safety measurement:\n3. Patient who had a cardiac pacemaker.\n4. Patient who had any metallic implant or device, such as drug pump, stent, etc.\n5. Patient who has or had any metal fragments in eye or any other part of body, or had ever worked with metal.","ALL","18 Years","85 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"NA","Endoscopic submucosal dissection (ESD) is a technique that allows curative treatment of early gastrointestinal neoplasia with organ preservation. However, it is a technically demanding procedure. Tissue traction plays a vital role in facilitating the visualization of the cutting line and the submucosal vessels, which usually only relies on the hood attached to the tip of the endoscope. However, when dealing with flat or large lesions, the absence of reliable traction in ESD contributes to its technical complexity and prolongs procedure duration. Various traction devices and techniques have been developed to provide tension for the dissection plane and optimal visibility during ESD. Most of these only provide static traction from a fixed angle, thus the effect of traction diminishes when the dissection continues.\n\nIn contrast to the aforementioned traction methods, magnetic traction offers the ability to externally manipulate an internal magnetic retractor, simplifying the internal workspace. The proposed magnetic retractor is composed of a detachable clip from an hemoclip is affixed to a magnetic element. By adjusting the position of the external magnetic source, the magnetic retractor automatically couples and aligns with it, enabling simultaneous dynamic directional control during the ongoing ESD operation. A novel robotic magnetic countertraction system was developed (MAG-ESD). The system consists of two sections: an external permanent magnetic source and the disposable magnetic retractor. The external permanent magnetic source is composed by a large external permanent magnet (EPM) which held by robot arm to externally control the locomotion of the magnetic retractor within patient. The disposable magnetic retractor is a consumable surgical instrument that modified from a commercial hemoclip, which has small magnets hangs on the clip legs. The design of the disposable magnetic retractor eliminates the need for endoscope withdrawal which can be inserted through the instrument channel from the handle during ESD operations, like other common instruments. In the current pilot study, the novel MAG-ESD counetrtraction system would be tested in 20 patients who undergo gastric and colonic ESD, with the aim of evaluating the system efficacy and safety.",[27,28],"Early Gastric Cancer","Colon Neoplasia",[30,31],"endoscopic submucosal dissection","magnetic retractor","RECRUITING","2025-04-30",{"date":35,"type":36},"2025-05-08","ACTUAL",{"date":38,"type":21},"2025-05-09",{"date":40,"type":21},"2026-06-30",{"name":42,"class":43},"Chinese University of Hong Kong","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":44},"100571060","prospective-study-of-using-novel-bipolar-scissors-in-colorectal-endoscopic-submucosal-dissection-100571060","NCT06715332","Prospective Study of Using Novel Bipolar Scissors in Colorectal Endoscopic Submucosal Dissection","Safety and Efficacy of the Novel SpydrBlade Flex With Radiofrequency and Microwave Ablation Flexible Bipolar for Colorectal Endoscopic Submucosal Dissection - A Prospective Study","Inclusion criteria:\n\n* Adult patient (age ≥18 and ≤80 years-old)\n* Capability of understanding and complying with the study requirements, including signing the informed consent form.\n* Patients with colorectal superficial mucosal neoplasia (clinically adenoma or early intramucosal cancer), scheduled to undergo endoscopic submucosal dissection (ESD).\n\nExclusion criteria:\n\n* Patients unable or unwilling to provide consent.\n* Patients with lesions unsuitable for ESD, including those suspicious of deep submucosal invasive cancer.\n* Patients with lesions involving the appendiceal orifice or ileocaecal valve.\n* Patients with significant cardiorespiratory comorbidities which may limit their ability to undertake monitored anesthesia for the procedure.\n* Poor performance status (Eastern Cooperation Oncology Group performance status ≥3).\n* Pregnant women or those planning pregnancy or breastfeeding women.\n* Uncorrectable coagulopathy defined by international normalized ratio (INR) \\> 1.5 or platelet count \\\u003C 50000\u002Fµl.","80 Years",{"count":54,"type":21},30,[24],"This study is an interventional, prospective, single-center study to evaluate the safety and effectiveness of a novel radiofrequency and microwave ablation flexible bipolar (SpydrBlade Flex, CREO Medical, UK) for colorectal ESD in patients with superficial colorectal neoplasia.",[58,28],"Colon Polyp",[60],"Endoscopic submucosal dissection","NOT_YET_RECRUITING","2024-11-29",{"date":64,"type":36},"2024-12-04",{"date":66,"type":21},"2024-12-08",{"date":68,"type":21},"2026-03-31",{"name":42,"class":43}]