[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"colon-polyp\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:colon-polyp":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,46,72,99,121,142,170,197,220,246],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100470196","st-pauls-advanced-resection-center-cohort-for-colorectal-neoplasia-sparc-c-100470196",false,"NCT05402696","St. Paul's Advanced Resection Center Cohort for Colorectal Neoplasia (SPARC-C)","The St. Paul's Hospital Advanced Endoscopic Resection Centre Cohort for Colorectal Neoplasia (SPARC-C): A Prospective Observational Study","SPARC-C","Inclusion Criteria:\n\n* Patients ≥ 18 years of age referred for the management of an LNPCP\n* Able to provide informed consent.\n\nExclusion Criteria:\n\n* Unable to provide informed consent\n* Pregnant or lactating women.","ALL","18 Years",{"count":20,"type":21},3500,"ESTIMATED","10 Years","OBSERVATIONAL","The SPARC-C study is a prospective, multi-institutional observational study of patients referred for the management of large (≥ 20mm) non-pedunculated colorectal polyps (LNPCPs). Patients are managed consistent with current standards of care. Prospectively collected data includes: patient clinicodemographic details, lesion details, procedural details, and clinical outcomes.",[26,27,28],"Colon Adenoma","Colon Polyp","Colon Lesion",[30,31,32],"Colorectal neoplasia","Advanced endoscopy","Endoscopic resection","RECRUITING","2026-05-12",{"date":36,"type":37},"2026-05-15","ACTUAL",{"date":39,"type":37},"2022-06-27",{"date":41,"type":21},"2032-12-31",{"name":43,"class":44},"University of British Columbia","OTHER",6,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":71},"100540506","pulsed-field-ablation-of-colorectal-polyps-100540506","NCT06317727","PULSed Field ablAtion of coloRectal Polyps","Pulsed Field Ablation of Colorectal Polyps","PULSAR","Inclusion Criteria:\n\n* \\> 18 years of age.\n* Ability to review the consent form prior to enrolment into the study • Patients must be mentally capable of understanding the information given • Patients must give written informed consent prior to undergoing any study-specific procedures.\n* Patients must have at least one polyp (treatment naive, recurrent or residual) measuring \\>5mm, located distal to the splenic flexure(i.e descending colon, Sigmoid colon, recto sigmoid junction and the rectum above the dentate line)\n* Polyp(s) must be classified as Type 1 or Type 2, based on NICE (Narrow Band Imaging International Colorectal Endoscopic) classification; OR Type 1 or Type 2A \u002F2B based on JNET (Japan Narrow Band Imaging Expert Team) classification\n* Patients must have a World Health Organization (WHO) performance status ≤ 2 . Patients must have a life expectancy of at least 6 months\n\nExclusion Criteria:\n\n* \\\u003C 18 years of age.\n* Patients who are incapacitated, unconscious or from a vulnerable population. • Patient who is pregnant or breastfeeding\n* Patients unable to provide their own informed consent\n* Patients with complex \u002F challenging polyp(s), including but not limited to those that are: o \\>20mm in size o Flat\u002Fbulky in shape o Extending beyond 2 haustra folds or occupying more than 1\u002F3rd of the lumenal circumference o Located on the right colon proximal to the splenic flexure, ileocecal valve, hepatic and splenic flexure or dentate line of the rectum o Fibrosis from large lateral spreading lesions\n* Patients with NICE Type 3 category polyps, OR JNET Type 3 polyps OR Kudo Vi pit pattern polyps\n* Patients with British Society of Gastroenterology (BSG) category C (high risk polyps).\n* Five or more polyps in a single patient\n* Grossly inflamed colonic mucosa with bleeding or ulcers\n* Implanted colonic stents\n* Polyposis syndromes",{"count":55,"type":21},30,"The goal of this observational study is to learn about the role of electroporation (the use of small electric pulses applied to tissue) in the treatment (ablation) of colorectal polyps. The main questions to answer in this pilot phase of the study are:\n\n1. The safety of pulsed field ablation (PFA) for the removal of colorectal polyps\n2. The efficacy and feasibility of PFA in the treatment of colorectal polyps using metrics such as treatment coverage, treatment time, post treatment fibrosis, post treatment recurrence and patient satisfaction",[27],[59,60,61],"Colorectal polyps","Irreversible electroporation","Endoscopic ablation","2026-02-27",{"date":64,"type":37},"2026-03-03",{"date":66,"type":37},"2025-03-26",{"date":68,"type":21},"2028-02",{"name":70,"class":44},"King's College Hospital NHS Trust",1,{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":17,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":83,"phases":84,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":4},"100616898","a-first-in-human-clinical-trial-evaluating-a-novel-colonic-intraluminal-endoscopic-support-structure-ciess-100616898","NCT07311590","A First-in-human Clinical Trial Evaluating a Novel Colonic Intraluminal Endoscopic Support Structure (CIESS)","A First-in-human Clinical Trial Evaluating the Feasibility of Performing Colonoscopic Polypectomy With a Novel Colonic Intraluminal Endoscopic Support Structure (CIESS) In-situ","Inclusion Criteria:\n\n* Positive fecal occult blood test\n\n  * ASA I\u002FII\n  * only patients with left-sided colonic polyp during colonoscopy will be included into the study eventually\n\nExclusion Criteria:\n\n* History of malignancy, gastrointestinal tract\u002F abdominal surgery, diverticular disease, abdominal\u002F pelvic radiation\n* Pregnancy patient\n* cognitively impaired patients\n* Patients on blood thinners or anticoagulants\n* ASA III \u002F ASA IV","21 Years","75 Years",{"count":82,"type":21},4,"INTERVENTIONAL",[85],"NA","The aim of the first-in-human clinical trial is to evaluate the feasibility of performing colonoscopic polypectomy with a novel colonic intraluminal endoscopic support structure (CIESS) in-situ",[27],"NOT_YET_RECRUITING","2025-12-29",{"date":91,"type":37},"2025-12-31",{"date":93,"type":21},"2025-12-18",{"date":95,"type":21},"2026-12-18",{"name":97,"class":98},"JurongHealth","OTHER_GOV",{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":106,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":107,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":109,"conditions":110,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":71},"100354157","collecting-recorded-videos-of-colonoscopy-100354157","NCT03891251","Collecting Recorded Videos of Colonoscopy","Collecting Recorded Videos of Colonoscopy Screening Tests for the Evaluation of the Automatic Polyp Detection System (APDS) Medical Device","Inclusion Criteria:\n\nSubjects must meet all the - criteria related to regular colonoscopy according to the standard of care at the Gastroenterology Department of the selected center, \\_In addition the following - criteria have to be met to be eligible for the study:\n\n1. Able to read, understand and provide written Informed Consent;\n2. Females or males - older than 18 years old\n\nExclusion Criteria:\n\nAny of the following colonoscopy related exclusion criteria will exclude the subject from the study:\n\n* Bleeding disorder or unacceptable risk of bleeding\n* Terminal illness or life threatening malignancy",true,{"count":108,"type":21},700,"The study shall mainly help to better evaluate the performance the APDS device and secondly it may help to assess the potential of the future alpha version of the device to be a useful and effective for the detection of colon Polyps.",[27],"2025-09-30",{"date":113,"type":37},"2025-10-06",{"date":115,"type":37},"2018-12-19",{"date":117,"type":21},"2026-12-31",{"name":119,"class":120},"Magentiq Eye LTD","INDUSTRY",{"id":122,"slug":123,"hasResults":11,"nctId":124,"briefTitle":125,"officialTitle":125,"acronym":126,"eligibilityCriteria":127,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":128,"enrollmentInfo":129,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":131,"conditions":132,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":71},"100321968","the-australian-colonic-large-sessile-lesion-endoscopic-resection-study-100321968","NCT03471793","The Australian Colonic Large Sessile Lesion Endoscopic Resection Study","ACE","Inclusion Criteria:\n\n* Patients referred for endoscopic resection of a large sessile colonic polyp or laterally spreading tumour ≥20mm in size.\n* Able to give informed consent to involvement in the clinical study\n\nExclusion Criteria:\n\n* Unable to provide informed consent for involvement","99 Years",{"count":130,"type":21},5000,"A prospective, multicentre, observational study of all patients referred for endoscopic resection of sessile colorectal polyps sized ≥20 mm conducted with intention to treat analysis",[26,27],"2025-03-25",{"date":135,"type":37},"2025-03-27",{"date":137,"type":37},"2017-02-24",{"date":139,"type":21},"2037-02",{"name":141,"class":44},"Western Sydney Local Health District",{"id":143,"slug":144,"hasResults":11,"nctId":145,"briefTitle":146,"officialTitle":146,"acronym":147,"eligibilityCriteria":148,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":149,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":151,"conditions":152,"keywords":157,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":71},"100444184","early-diagnosis-real-time-healthcare-system-for-cancer-trial-100444184","NCT05064124","Early DiAgnosis Real-Time Healthcare System for CANcer Trial","EARTHSCAN","Inclusion Criteria:\n\n* Participants scheduled to undergo a screening, surveillance or symptomatic colonoscopy with an endoscopist participating in the study phase of the trial.\n* Male and female participants aged 18 years or older at the time of informed consent.\n* Participants able to comprehend, sign and date the written informed consent document to participate in the study.\n\nExclusion Criteria:\n\n* Emergency and\u002For inpatient colonoscopies\n* Participants with inflammatory bowel disease (IBD)\n* Participants with current Colorectal Cancer (CRC)\n* Participants with a contraindication for biopsy or polypectomy. These include:\n\n  * Participants who have not withheld medications pre-disposing to bleeding at time of colonoscopy as per local site \u002Fnational guidelines.\n  * Participants with a history of haemostasis disorders (haemostasis disorders will include but will not be limited to: participants with haemophilia or other congenitally acquired clotting factor deficiencies, participants with cirrhosis with coagulopathy, participants known to have thrombocytopenia (\\\u003C80,000 platelet\u002Ful) and individuals with Von Willebrand's disease or other known platelet malfunction disorders)\n* Participant is enrolled in another research study with an investigational medicinal product (IMP) or non-IMP that pre-disposes them to bleeding",{"count":150,"type":21},420,"The purpose of the study is to assess whether the AI characterisation system of the CADDIE device improves the endoscopists accuracy in the optical diagnosis of diminutive colorectal polyps in the bowel during colonoscopy. Participants will either have a colonoscopy with the assistance of the CADDIE device characterisation AI system (\"intervention group\") or have a colonoscopy in line with routine clinical practice i.e., without the CADDIE device characterisation AI system (\"control group\"). The randomisation method of this trial will allocate enrolled participants to the \"intervention\" group and to the \"control\" group by a technique similar to flipping a coin.",[153,154,155,27,156],"Polyps","Adenoma Colon","Colorectal Polyp","Polyps of Colon",[158,159,160],"Artificial intelligence","Endoscopy","ADR","2024-12-10",{"date":163,"type":37},"2024-12-16",{"date":165,"type":37},"2024-07-18",{"date":167,"type":21},"2025-05",{"name":169,"class":44},"University College, London",{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":106,"sex":17,"minAge":177,"maxAge":178,"enrollmentInfo":179,"targetDuration":4,"studyType":83,"phases":181,"briefSummary":182,"conditions":183,"keywords":184,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":188,"lastUpdatePostDateStruct":189,"startDateStruct":191,"completionDateStruct":193,"leadSponsor":195,"locationsCount":71},"100515339","artificial-intelligence-in-the-detection-of-right-sided-colonic-polyp-in-different-operator-experience-100515339","NCT05990218","Artificial Intelligence in the Detection of Right Sided Colonic Polyp in Different Operator Experience","Efficacy of Artificial Intelligence in the Detection of Right Sided Colonic Polyp in Operators with Different Endoscopic Experience: a Randomized Control Trial","Inclusion Criteria:\n\n* participants age 40-80 years\n\nExclusion Criteria:\n\n* History of colonic surgery (except appendectomy)\n* Lower gastrointestinal bleeding\n* unstable vital sign during endoscopy of pregnancy\n* history of inflammatory bowel disease, polyposis syndrome, colon cancer, colonic stricture, abnormal coaglulation, organ failure","40 Years","80 Years",{"count":180,"type":21},240,[85],"Colonoscopy is the gold standard modality for the detection of colonic polyp. However, miss polyp occurs especially in right sided colon. Artificial intelligence (AI) is one of the modality to improve polyp detection but the benefit of AI in operators with different endoscopic experience is still limited. This study aimed to evaluate the efficacy of AI in the detection of right sided colonic polyp in operators with different endoscopic experience by using double insertion of right side colon, back-to-back basis.",[27],[185,186,187],"colon polyp","artificial intellegence","colonoscopy","2024-12-09",{"date":190,"type":37},"2024-12-13",{"date":192,"type":37},"2023-02-13",{"date":194,"type":21},"2026-02-28",{"name":196,"class":98},"Department of Medical Services Ministry of Public Health of Thailand",{"id":198,"slug":199,"hasResults":11,"nctId":200,"briefTitle":201,"officialTitle":202,"acronym":4,"eligibilityCriteria":203,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":178,"enrollmentInfo":204,"targetDuration":4,"studyType":83,"phases":205,"briefSummary":206,"conditions":207,"keywords":209,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":211,"lastUpdatePostDateStruct":212,"startDateStruct":214,"completionDateStruct":216,"leadSponsor":218,"locationsCount":71},"100571060","prospective-study-of-using-novel-bipolar-scissors-in-colorectal-endoscopic-submucosal-dissection-100571060","NCT06715332","Prospective Study of Using Novel Bipolar Scissors in Colorectal Endoscopic Submucosal Dissection","Safety and Efficacy of the Novel SpydrBlade Flex With Radiofrequency and Microwave Ablation Flexible Bipolar for Colorectal Endoscopic Submucosal Dissection - A Prospective Study","Inclusion criteria:\n\n* Adult patient (age ≥18 and ≤80 years-old)\n* Capability of understanding and complying with the study requirements, including signing the informed consent form.\n* Patients with colorectal superficial mucosal neoplasia (clinically adenoma or early intramucosal cancer), scheduled to undergo endoscopic submucosal dissection (ESD).\n\nExclusion criteria:\n\n* Patients unable or unwilling to provide consent.\n* Patients with lesions unsuitable for ESD, including those suspicious of deep submucosal invasive cancer.\n* Patients with lesions involving the appendiceal orifice or ileocaecal valve.\n* Patients with significant cardiorespiratory comorbidities which may limit their ability to undertake monitored anesthesia for the procedure.\n* Poor performance status (Eastern Cooperation Oncology Group performance status ≥3).\n* Pregnant women or those planning pregnancy or breastfeeding women.\n* Uncorrectable coagulopathy defined by international normalized ratio (INR) \\> 1.5 or platelet count \\\u003C 50000\u002Fµl.",{"count":55,"type":21},[85],"This study is an interventional, prospective, single-center study to evaluate the safety and effectiveness of a novel radiofrequency and microwave ablation flexible bipolar (SpydrBlade Flex, CREO Medical, UK) for colorectal ESD in patients with superficial colorectal neoplasia.",[27,208],"Colon Neoplasia",[210],"Endoscopic submucosal dissection","2024-11-29",{"date":213,"type":37},"2024-12-04",{"date":215,"type":21},"2024-12-08",{"date":217,"type":21},"2026-03-31",{"name":219,"class":44},"Chinese University of Hong Kong",{"id":221,"slug":222,"hasResults":11,"nctId":223,"briefTitle":224,"officialTitle":225,"acronym":4,"eligibilityCriteria":226,"healthyVolunteers":106,"sex":17,"minAge":227,"maxAge":178,"enrollmentInfo":228,"targetDuration":4,"studyType":83,"phases":230,"briefSummary":231,"conditions":232,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":236,"lastUpdatePostDateStruct":237,"startDateStruct":239,"completionDateStruct":241,"leadSponsor":243,"locationsCount":245},"100554274","water-exchange-and-co2-insufflation-with-abdominal-compression-device-to-reduce-manual-assistance-100554274","NCT06496958","Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance","CO2 Insufflation Colonoscopy With an Abdominal Compression Device and Water Exchange Colonoscopy to Reduce Manual Assistance by Endoscopy Staff: A Multicenter Randomized Trial","Inclusion Criteria:\n\n* Patients aged 45-80 years having an average risk for colorectal cancer who plan to undergo sedated outpatient colonoscopy for screening, surveillance, and those who have received a positive fecal immunochemical test result\n\nExclusion Criteria:\n\n* Patients with hereditary colorectal cancer syndrome, including familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer (Lynch syndrome)\n* Patients with serrated polyposis syndrome\n* Patients with known or suspected inflammatory bowel disease\n* Patients with a history of colorectal cancer or other intra-abdominal malignancy\n* Patients with a history of colorectal resection\n* Patients with a history of abdominal aortic aneurysm, cirrhosis, ascites, or other severe comorbid illnesses\n* Patients with recent wounds or skin rash on the anterior abdominal wall and back\n* Patients with known ventral hernia\n* Patients with unsedated procedure\n* Patients with planned bidirectional endoscopy\n* Patients with body mass index \\>35 kg\u002Fm2\n* Patients with waist circumference \\\u003C55 cm or \\>105 cm\n* Patients with known or suspected gastroparesis\n* Patients with planned therapeutic procedures (e.g., hemostasis, removal of a large polyp)\n* Patients with mental retardation\n* Pregnant women or those planning pregnancy\n* Patients unwilling to participate in the study","45 Years",{"count":229,"type":21},400,[85],"The goal of this trial is to evaluate whether water exchange colonoscopy and CO2-insufflation colonoscopy with an abdominal compression device (Maxbelt me3 type, Nippon Sigmax Co., Tokyo, Japan) can achieve a significantly lower proportion of patients requiring manual abdominal pressure during colonoscopic insertion compared with CO2 insufflation alone.",[233,234,235,27],"Manual Pressure","Repositioning","Colonoscopy","2024-11-03",{"date":238,"type":37},"2024-11-05",{"date":240,"type":37},"2024-09-02",{"date":242,"type":21},"2026-09-30",{"name":244,"class":44},"Evergreen General Hospital, Taiwan",2,{"id":247,"slug":248,"hasResults":11,"nctId":249,"briefTitle":250,"officialTitle":251,"acronym":4,"eligibilityCriteria":252,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":253,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":254,"conditions":255,"keywords":256,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":257,"lastUpdatePostDateStruct":258,"startDateStruct":260,"completionDateStruct":262,"leadSponsor":264,"locationsCount":71},"100559649","collecting-recorded-videos-of-colonoscopy-and-gastroscopy-tests-for-the-evaluation-of-the-me-apds-100559649","NCT06566872","Collecting Recorded Videos of Colonoscopy and Gastroscopy Tests for the Evaluation of the (ME-APDS).","Collecting Recorded Videos of Colonoscopy Gastroscopy Tests for the Evaluation of the Magentiq Eye Automatic Polyp Detection System (ME-APDS) Medical Device","Inclusion Criteria:\n\nSubjects must meet all the - criteria related to regular colonoscopy and\u002For gastroscopy according to the standard of care at the Gastroenterolgy Department of the selected center, \\_In addition the following - criteria have to be met to be eligible for the study:\n\n1. Able to read, understand and provide written Informed Consent;\n2. Females or males - older than 18 years old\n\nExclusion Criteria:\n\nAny of the following colonoscopy\u002Fgastroscopy related exclusion criteria will exclude the subject from the study:\n\n* Bleeding disorder or unacceptable risk of bleeding\n* Terminal illness or life threatening malignancy",{"count":108,"type":21},"The study shall mainly help to better evaluate the performance the ME-APDS device and secondly it may help the development of additional future versions of the ME-APDS.\n\nPrimary endpoints\n\n* Clear video of the colon or the stomach or the esophagus achieved during the test.\n* Acceptable colon or gastro test performance according to the standards, criteria, and regulations of the medical center of the trial.\n\nSecondary endpoints\n\n• A recorded video of at least 80% of the actual test duration.",[27],[153],"2024-08-25",{"date":259,"type":37},"2024-08-28",{"date":261,"type":37},"2022-05-16",{"date":263,"type":21},"2025-12",{"name":119,"class":120}]