[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"colorectal-disorders\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:colorectal-disorders":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,12,0,[8,45,66,117,145,173,202,224,262,289,314,336],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100543491","adapting-enhanced-recovery-programs-for-low-health-literacy-patients-100543491",false,"NCT06356558","Adapting Enhanced Recovery Programs for Low Health Literacy Patients","Inclusion Criteria:\n\n* Adult patients \\>= 18 years of age undergoing surgery under an enhanced recovery program (ERPs)\n* Adult caregivers\u002Fproviders, organizational leaders, \\>= 18 years of age with direct or indirect involvement with ERP implementation\n* All genders\n* All race\u002Fethnicities\n* Able to consent\n* English-speaking\n\nExclusion Criteria:\n\n* Child (\\\u003C18 years of age)\n* Patients undergoing operations not included under ERPs\n* Participants unable to consent for the study\n* Participants whose mental state excludes them from being able to understand contents of the informed consent form and\u002For patients whose family members or patient representative do not wish for them to participate in the study",true,"ALL","18 Years",{"count":19,"type":20},1050,"ESTIMATED","INTERVENTIONAL",[23],"NA","Low health literacy patients are a vulnerable population at high-risk for surgical disparities including longer hospital stays, more complications, and more readmissions. This study will adapt enhanced recovery programs (ERPs) to low health literacy patients with a multilevel, health literacy-based implementation strategy (called VISACT - VISuAl aids, Coach providers in communication, and Train organizations in health literacy) to improve ERP fidelity and thereby outcomes. In the final aim of this project (Specific Aim 3), the VISACT intervention will be tested in a pilot trial. Findings from this study will lay the foundation for a multi-institutional stepped-wedge trial and establish key principles for adapting interventions to eliminate disparities.",[26,27,28],"Surgery","Health Knowledge, Attitudes, Practice","Colorectal Disorders",[26,30,31],"Health Literacy","Enhanced Recovery","RECRUITING","2026-06-25",{"date":35,"type":36},"2026-06-29","ACTUAL",{"date":38,"type":36},"2026-06-15",{"date":40,"type":20},"2028-05-01",{"name":42,"class":43},"University of Alabama at Birmingham","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":44},"100380633","home-to-stay-mobile-app-for-colorectal-surgery-100380633","NCT04236128","Home to Stay Mobile App for Colorectal Surgery","Home To Stay: An Integrated Monitoring System Using a Mobile App to Reduce Readmissions Following Colorectal Surgery","Inclusion Criteria:\n\n* any patient who is being discharged to home after undergoing elective colorectal surgery\n* 18 years or older\n* able to speak and understand English or French\n* provides informed consent\n\nExclusion Criteria:\n\n* post-operative admission less than 3 days\n* requiring discharge to rehabilitation centre to recover prior to being able to go home",{"count":53,"type":20},670,[23],"Background: Colorectal surgery includes surgery for colorectal cancer, inflammatory bowel disease and other benign diseases such as diverticulitis. In Canada, approximately 21,000 colorectal surgeries are performed each year. Patients undergoing colorectal surgery face high rates of unplanned hospital visits including readmission to hospital and Emergency Room (ER) visits. These unplanned hospital visits lead to significant distress and anxiety for patients and increased health care costs.\n\nResearch Aims: The goal is to evaluate the use of an integrated discharge monitoring system with a mobile application (app) to support colorectal surgery patients at home following discharge from hospital.\n\nMethods: The study will include 3 hospitals across Canada. Patients will be assigned to either a control group or intervention group. Control group patients will receive standard follow up care after going home following surgery. Intervention group patients will be enrolled in an integrated discharge monitoring system using an app to monitor their progress at home following discharge after surgery. The main outcomes are to measure the number of patients with unplanned hospital visits within 30 days of discharge following surgery, the quality of patient recovery and confidence managing one's own health care. Patients are eligible if they are being discharge home after having elective colorectal surgery, are 18 years or older and speak and understand English or French. At the end of the study, the outcomes between the control group and intervention group will be compared to look for important differences.\n\nExpected Outcomes: It is expected that the results of this study will show that the integrated discharge monitoring system will lead to a significant improvement in the quality of patient recovery and self-confidence with one's own health care, as well as significantly reduce the number of unplanned hospital visits for patients undergoing colorectal surgery in Canada.",[28],"2026-06-17",{"date":59,"type":36},"2026-06-22",{"date":61,"type":36},"2021-05-25",{"date":63,"type":20},"2028-12",{"name":65,"class":43},"Mount Sinai Hospital, Canada",{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":74,"targetDuration":4,"studyType":76,"phases":4,"briefSummary":77,"conditions":78,"keywords":96,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":109,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":116},"100542405","early-detection-of-advanced-adenomas-and-colorectal-cancer-100542405","NCT06342440","Early Detection of Advanced Adenomas and Colorectal Cancer","A Liquid Biopsy Assay For The Non-Invasive Early Detection of Advanced Adenomas and Colorectal Cancer","AACRC","Inclusion Criteria:\n\n* All individuals included in the study need to have had a colonoscopy at the time of blood sampling.\n* Received standard diagnostic and staging (as necessary) procedures as per local guidelines, and at least one sample was drawn before receiving any curative-intent treatment.\n* Received standard pathological and endoscopic diagnosis and assessment for cohort assignment.\n\nExclusion Criteria:\n\n* Hereditary colorectal cancer syndromes (identified through genetic testing).\n* Inflammatory bowel diseases.\n* Lack of written informed consent.",{"count":75,"type":20},2000,"OBSERVATIONAL","This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.",[79,80,81,82,28,83,84,85,86,87,88,89,90,91,92,93,94,95],"Colorectal Cancer","Colorectal Neoplasms","Colorectal Polyp","Colorectal Adenocarcinoma","Colorectal Dysplasia","Colorectal Cancer Stage I","Colorectal Cancer Stage II","Colorectal Cancer Stage III","Colorectal Cancer Stage IV","Colorectal Neoplasms Malignant","Colorectal Serrated Adenocarcinoma","Colorectal Adenoma With Severe Dysplasia","Colorectal Adenoma With Mild Dysplasia","Colorectal Adenoma With Moderate Dysplasia","Colorectal Adenoma and Carcinoma 1","Colorectal Adenomatous Polyp","Colorectal Adenocarcinoma Metastatic in the Liver",[97,98,99,100,101,102,103,104,105,106,107,108],"Early detection","Micro RNA","miRNA","Liquid biopsy","Machine learning","Artificial Intelligence","Incidence","Polypectomy","Screening","Surveillance","Exosome","Vascicles",{"date":57,"type":36},{"date":111,"type":36},"2020-03-15",{"date":113,"type":20},"2026-06-18",{"name":115,"class":43},"City of Hope Medical Center",6,{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":121,"acronym":4,"eligibilityCriteria":122,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":123,"enrollmentInfo":124,"targetDuration":4,"studyType":21,"phases":126,"briefSummary":128,"conditions":129,"keywords":133,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":136,"lastUpdatePostDateStruct":137,"startDateStruct":139,"completionDateStruct":141,"leadSponsor":143,"locationsCount":44},"100566649","phase-2-preoperative-tranexamic-acid-txa-to-prevent-bleeding-in-patients-undergoing-major-colorectal-surgery-100566649","NCT06657924","Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery","Inclusion Criteria:\n\n1. Adults 18 years or older\n2. Undergoing elective or non-elective inpatient abdominal and pelvic colorectal surgery\n\nExclusion Criteria:\n\n1. Creatinine clearance less than 30 mL\u002Fminute\n2. Long-term dialysis\n3. Known defective color vision (color blind)\n4. Pregnancy\n5. History of venous or arterial thromboembolism, or active thromboembolic disease\n6. Disseminated intravascular coagulation (DIC) - clinically suspected and\u002For confirmed by platelet count on CBC, fibrinogen, INR and PTT.","100 Years",{"count":125,"type":20},394,[127],"PHASE2","The goal of this prospective pragmatic randomized clinical trial is to determine if preoperative administration of tranexamic acid (TXA) reduces bleeding during and after major colorectal surgery. The primary questions are:\n\n* Does TXA reduce bleeding during and after surgery (change in hemoglobin from before surgery to lowest value after surgery within 30 days)\n* Does TXA reduce bleeding complications within 30 days of surgery (blood transfusion, return to the operating room or procedural intervention for bleeding, death due to bleeding)\n* Does TXA increase the risk of thromboembolic complications within 30 days of surgery (cerebrovascular accident, myocardial infarction, deep venous thrombosis, pulmonary embolism)\n\nResearchers will compare preoperative TXA to no TXA to answer the above questions.\n\nParticipants who receive TXA will receive 1 g TXA IV at the beginning and end of surgery in the operating room.",[130,28,131,132],"Bleeding","Thromboembolism","Tranexamic Acid",[132,134,130,135,131],"TXA","Colorectal Surgery","2026-05-27",{"date":138,"type":36},"2026-05-28",{"date":140,"type":36},"2025-02-11",{"date":142,"type":20},"2027-10-01",{"name":144,"class":43},"Kristen Ban",{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":149,"acronym":4,"eligibilityCriteria":150,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":151,"targetDuration":4,"studyType":21,"phases":153,"briefSummary":154,"conditions":155,"keywords":159,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":164,"lastUpdatePostDateStruct":165,"startDateStruct":167,"completionDateStruct":169,"leadSponsor":171,"locationsCount":44},"100463933","evaluation-of-single-port-sp-robotic-technology-in-colorectal-surgery-100463933","NCT05321134","Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery","Inclusion Criteria:\n\n* The subject is male or female, greater than or equal to 18 years of age. If female, the subject has a negative urine pregnancy test and is not lactating, or has not been of childbearing potential for at least 3 months prior to use of study product. To be considered to be not of childbearing potential, the subject must be postmenopausal for at least 2 years; have had a hysterectomy or bilateral tubal ligation, or be proven to be otherwise incapable of pregnancy. If of childbearing potential, the subject must have been practicing one of the following methods of contraception consistently for at least 1 month prior to study entry and agree to continue practicing it during the study: hormonal contraceptives, intrauterine device, spermicide and barrier, spouse\u002Fpartner sterility; or is practicing abstinence and agrees to continue abstinence or to start an acceptable method of contraception from the above list if sexual activity commences.\n* There is documentation of a colorectal diagnosis requiring operative interventions with clinical plans for a robotic operation.\n* For robotic transanal procedures, patients who would meet standard guidelines for a transanal procedures (T1N0 rectal adenocarcinoma, Precancerous adenomas, and localized neuroendocrine tumors) distal to 15 cm from the anal verge.\n* The subject is in good general health as evidenced by medical history and physical examination\n* The subject is able and willing to provide written informed consent.\n* The subject agrees to comply with the requirements of the protocol and complete study measures.\n* The subject has stable residence and telephone.\n\nExclusion Criteria:\n\n* The subject is child less than 18 years of age\n* The subject is a female who is pregnant or lactating\n* The subject falls under the American Society of Anesthesia Class IV (Patients with severe systemic disease that is a constant threat to life).\n* The subject falls under American Society of Anesthesia Class V (Moribund patients who is not expected to survive without the operation)\n* The subject has a history of clinically significant renal, hepatic, neurological, cardiac or chronic pulmonary disease that in the judgment of the investigator precludes participation.\n* The subject has advanced\u002F Stage IV cancer\n* The subject has received neo-adjuvant chemotherapy or radiation therapy\n* The subject requires an emergency operation.\n* The subject is unable to fully comprehend or consent to the study\n* The subject is unwilling to be available for follow-up assessments.",{"count":152,"type":20},25,[23],"Currently a multiport robotic surgery platform (Intuitive Xi) is widely available and used for colorectal surgery indications. A Single port platform (Intuitive SP) is FDA approved for Head and Neck and Urology but has not been widely used in colorectal surgery. This study seeks to evaluate the safe and effective use of the SP platform for colorectal surgery indications.",[156,157,158,28],"Colo-rectal Cancer","Rectal Prolapse","Colostomy Stoma",[160,161,162,163],"robotic surgery","colorectal surgery","single port","Intuitive SP platform","2026-05-26",{"date":166,"type":36},"2026-05-29",{"date":168,"type":36},"2022-04-28",{"date":170,"type":20},"2028-04",{"name":172,"class":43},"University of California, Davis",{"id":174,"slug":175,"hasResults":11,"nctId":176,"briefTitle":177,"officialTitle":178,"acronym":179,"eligibilityCriteria":180,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":181,"enrollmentInfo":182,"targetDuration":4,"studyType":21,"phases":184,"briefSummary":186,"conditions":187,"keywords":191,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":193,"lastUpdatePostDateStruct":194,"startDateStruct":196,"completionDateStruct":198,"leadSponsor":200,"locationsCount":44},"100495050","phase-4-fluid-challenge-and-plasma-volume-during-surgery-100495050","NCT05726136","Fluid Challenge and Plasma Volume, During Surgery","Comparison of Albumin and Ringer's Solution for Optimization of the Plasma Volume and Hemodynamics During Laparoscopic Surgery.","FC-VE","Inclusion Criteria:\n\n* Written consent to participate in the study\n* For women: relevant contraceptive, menopausal or a negative pregnancy test.\n* ASA category I to III\n* Laparoscopic abdominal surgery, with a duration of at least 90 minutes.\n* 18 to 85 years\n\nExclusion Criteria:\n\n* Patients with known cardiac failure\n* \\\u003C18 or \\>85 years\n* known allergy to albumin\n* extracellular hyperhydration or hypervolemia\n* kidney failure\n* pregnancy or planned pregnancy","85 Years",{"count":183,"type":20},60,[185],"PHASE4","A short bolus infusion of fluid, called \"fluid challenge\" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the blood volume is a prerequisite to recommend the technique. The purpose with the study is to examine the plasma expanding effect of three different fluid challenge strategies (acetated Ringers 4 ml\u002Fkg body weight, albumin 5% 4 ml\u002Fkg body weight or albumin 20% 1 ml\u002Fkg body weight), using hemoglobin as a dilution indicator.",[79,188,189,28,190],"Urologic Cancer","Gynecologic Cancer","Benign Neoplasm",[192],"laparoscopic surgery, fluid therapy, plasma volume","2026-04-24",{"date":195,"type":36},"2026-04-30",{"date":197,"type":36},"2023-10-23",{"date":199,"type":20},"2026-10-31",{"name":201,"class":43},"Joachim Zdolsek",{"id":203,"slug":204,"hasResults":11,"nctId":205,"briefTitle":206,"officialTitle":207,"acronym":208,"eligibilityCriteria":209,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":210,"targetDuration":4,"studyType":21,"phases":212,"briefSummary":213,"conditions":214,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":215,"lastUpdatePostDateStruct":216,"startDateStruct":218,"completionDateStruct":220,"leadSponsor":222,"locationsCount":44},"100351970","intra-corporeal-anastomosis-result-in-quicker-return-of-bowel-functionearlier-discharge-100351970","NCT03862781","Intra-Corporeal Anastomosis Result in Quicker Return of Bowel Function\u002FEarlier Discharge","Randomized Trial of Intra-Corporeal Anastomosis for RighT Colectomies (RICART Study)","RICART","Inclusion Criteria:\n\n* Eligible patients are those over 18 years of age who are regularly scheduled to undergo a right hemicolectomy via a minimally invasive approach (robotic or laparoscopic) with the creation of an anastomosis. Right colectomy will be defined as removal of the ascending colon, ligation of the ileocolic artery and vein, +\u002F- removal of the terminal ileum, +\u002F- removal of the proximal transverse colon, and +\u002F- removal of the right branch of the middle colic artery and vein.\n\nExclusion Criteria:\n\n* Pregnant women\n* Additional colon resection is planned (i.e. left colectomy or proctectomy)\n* Vulnerable populations such as prisoners or adults unable to give consent\n* If the scheduled surgery is planned at Butterworth hospital (as to standardize the nursing care received postoperatively)\n* Emergent cases\n\nPatients will be excluded from the study intra-operatively if:\n\n* The procedure is converted to an open resection\n* If a loop ileostomy is performed in addition to the right colectomy",{"count":211,"type":20},125,[23],"Adult patients who are regularly scheduled to undergo a right hemicolectomy via a minimally invasive approach (robotic or laparoscopic) with the creation of an anastomosis.",[28],"2026-01-20",{"date":217,"type":36},"2026-01-21",{"date":219,"type":36},"2019-01-28",{"date":221,"type":20},"2027-12",{"name":223,"class":43},"Corewell Health West",{"id":225,"slug":226,"hasResults":11,"nctId":227,"briefTitle":228,"officialTitle":229,"acronym":230,"eligibilityCriteria":231,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":232,"targetDuration":4,"studyType":21,"phases":234,"briefSummary":235,"conditions":236,"keywords":247,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":253,"lastUpdatePostDateStruct":254,"startDateStruct":256,"completionDateStruct":258,"leadSponsor":260,"locationsCount":44},"100549201","biological-ovitex-versus-synthetic-graft-in-robotic-prolapse-surgery-100549201","NCT06430931","Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery","Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery: a Multicentre, Phase 11-111, Partially Randomised Patient Preference Trial","ProTex","Inclusion Criteria:\n\n* Indication for VMR or SCR set by the treating surgeon\u002Fgynecologist in accordance to the current guidelines on rectal and pelvic prolapse;\n* Counselled for therapeutic options and given informed consent for VMR or SCR;\n* Counselled for different types of mesh (OviTex or Prolene) and randomisation;\n* Written informed consent for randomisation, OviTex implant or Prolene;\n* Written informed consent for observational data collection.\n\nExclusion Criteria:\n\n* Mentally incompetent patients (unable to fulfil questionnaires).\n* Allergy to ovine rumen.\n* A medical history of pelvic radiation therapy.\n* Scheduled for a redo-rectopexy.\n* A medical history of previously implanted pelvic floor meshes or native tissue.\n* Language barrier",{"count":233,"type":20},184,[23],"This prospective study aims to assess the efficacy of the OviTex 1S permanent mesh in pelvic floor surgery in comparison with the current standard polypropylene mesh.",[28,237,238,239,240,241,242,243,244,245,246],"Prolapse","Prolapse Rectal","Prolapse Genital","Prolapse Pelvic","Rectocele","Prolapse Uterus","Cystocele","Enterocele","Prolapse Bladder","Prolapse; Cervix",[237,248,249,250,251,252],"Abdominal prolapse Surgery","Biological mesh","OviTex","VMR","sacrocolporectopexy","2025-12-31",{"date":255,"type":36},"2026-01-02",{"date":257,"type":36},"2023-12-06",{"date":259,"type":20},"2027-07-01",{"name":261,"class":43},"Meander Medical Center",{"id":263,"slug":264,"hasResults":11,"nctId":265,"briefTitle":266,"officialTitle":267,"acronym":4,"eligibilityCriteria":268,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":269,"targetDuration":4,"studyType":21,"phases":271,"briefSummary":272,"conditions":273,"keywords":276,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":280,"lastUpdatePostDateStruct":281,"startDateStruct":283,"completionDateStruct":285,"leadSponsor":287,"locationsCount":44},"100539863","phase-4-ostomy-primary-closure-with-01-betainepolyhexanide-wound-irrigation-compared-to-pursestring-closure-100539863","NCT06309368","Ostomy Primary Closure With 0.1% Betaine\u002FPolyhexanide Wound Irrigation Compared to Pursestring Closure","To Close or Not to Close: Surgical Site Infection Rates in Ostomy Primary Closure With 0.1% Betaine\u002FPolyhexanide Wound Irrigation Compared to Conventional Ostomy Closure by Secondary Intention","Inclusion Criteria:\n\n* All patients 18 years or older with an diverting loop ileostomy reversal indication will be enrolled\n* Signed consent\n\nExclusion Criteria:\n\n* Under 18 years old, unable to provide consent, has a parastomal hernia requiring mesh repair, or has an end ileostomy",{"count":270,"type":20},84,[185],"The goal of this clinical trial is to compare two types of closure in patients with ostomies that are ready for closure. The main questions it aims to answer are:\n\n1. Surgical site infection rates\n2. Patient quality of life\n3. Time to wound healing\n\nParticipants will undergo either complete ostomy wound closure after washing out the wound with Prontosan, or their ostomy wound will be closed using the Pursestring method, where the wound will be left partially open and allowed to heal from the inside out. Researchers will compare these two groups' outcomes (questions to be answered) as listed above.",[274,275,28],"Surgical Site Infection","Wound Surgical",[277,274,278,279],"Ostomy","Primary Closure","Secondary Closure","2025-05-27",{"date":282,"type":36},"2025-06-02",{"date":284,"type":36},"2024-03-14",{"date":286,"type":20},"2029-12",{"name":288,"class":43},"University of Nevada, Las Vegas",{"id":290,"slug":291,"hasResults":11,"nctId":292,"briefTitle":293,"officialTitle":294,"acronym":4,"eligibilityCriteria":295,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":296,"enrollmentInfo":297,"targetDuration":4,"studyType":76,"phases":4,"briefSummary":299,"conditions":300,"keywords":301,"overallStatus":304,"whyStopped":4,"lastUpdateSubmitDate":305,"lastUpdatePostDateStruct":306,"startDateStruct":308,"completionDateStruct":310,"leadSponsor":312,"locationsCount":44},"100556908","difficult-colonoscopy-and-personality-traits-100556908","NCT06531226","Difficult Colonoscopy and Personality Traits","Personality Traits and Colonoscopy Insertion Time: Applying Machine Learning to Predict the Colonoscopy Time and Difficult Colonoscopy","Inclusion Criteria:\n\n* Colonoscopy patients tested 18 to 60 years old, men and women there is no limit\n* Insert the cecum complete colonoscopy examination (successfully)\n* Agree and complete personality questionnaire and anxiety depression\n\nExclusion Criteria:\n\n* Maternal\u002Fpregnancy\u002Flactation\n* Has a history of colorectal resection of colorectal surgery\n* Have organic diseases such as severe ulcerative colitis or intestinal tumors\n* Inadequate bowel preparation (bowel with feces and less than 90% visible area of mucosa)\n* Confirmed with the immune system (SLE), nervous system (Alzheimer's disease), mental system (such as schizophrenia, depression), urinary system disease (CKD), and other digestive system disease\n* Unable or unwilling to sign informed consent","60 Years",{"count":298,"type":20},450,"The cecal intubation time (CIT) refers to the time required for the tip of the colonoscope to reach the cecum from passing through the anus. A prolonged CIT is considered a marker of difficulty in colonoscopy. CIT greater than 10 minutes is considered a difficult colonoscopy. Studies have identified factors that influence CIT, including age, gender, body mass index (BMI), waist circumference, bowel preparation, prior abdominal surgery, etc. Personality traits have been found to be associated with the onset of many diseases, such as hypertension and A-type personality, depression and neurotic personality. According to the Big Five personality theory, personality can be decomposed into five dimensions: openness (O), conscientiousness (C), extraversion (E), agreeableness (A), and neuroticism (N). There is a lack of research on the association between personality traits and colonoscopy insertion time, and the purpose of this study is to investigate whether personality, BMI, age, gender, anxiety and depression index, metabolic diseases, and abdominal pelvic surgery history lead to prolonged colonoscopy insertion time and difficult colonoscopy, and to identify significant variables as predictors by using machine learning methods to build a clinical diagnostic model to predict colonoscopy insertion time and identify difficult colonoscopy patients.",[28],[302,303],"machine learning","difficult colonoscopy","NOT_YET_RECRUITING","2024-07-28",{"date":307,"type":36},"2024-07-31",{"date":309,"type":20},"2024-07-30",{"date":311,"type":20},"2025-05-01",{"name":313,"class":43},"Qilu Hospital of Shandong University",{"id":315,"slug":316,"hasResults":11,"nctId":317,"briefTitle":318,"officialTitle":319,"acronym":320,"eligibilityCriteria":321,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":322,"targetDuration":324,"studyType":76,"phases":4,"briefSummary":325,"conditions":326,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":327,"lastUpdatePostDateStruct":328,"startDateStruct":330,"completionDateStruct":332,"leadSponsor":334,"locationsCount":44},"100542192","post-operative-complications-and-smoking-habits-in-colorectal-surgery-100542192","NCT06339671","Post-operative Complications and Smoking Habits in Colorectal Surgery","Complicanze Post-operatorie e Abitudine Tabagica in Chirurgia Colorettale (Studio PASSAGE). Uno Studio Multicentrico Osservazionale Prospettico e Retrospettivo in Italia","PASSAGE","Inclusion Criteria:\n\n* Patients ≥ 18 years old.\n* Patients who have read, understood, accepted and signed the informed consent to the study.\n* Patients with benign or malignant colorectal disease.\n* Patients undergoing colorectal surgery with any type of approach (open or minimally invasive) in Italy.\n* Patients undergoing elective and emergency colorectal surgery.\n* Patients NF (non smoker), FT (tobacco smokers), NRT (nicotine replacement therapy). Are considered smokers that patients who have smoked for at least 30 days at the time of surgery\n\nExclusion Criteria:\n\n* Patients \\\u003C 18 years old.\n* Patients who have not accepted informed consent.",{"count":323,"type":20},1527,"30 Days","PASSAGE is a national multicenter retrospective and prospective observational cohort study in which patients who will undergo colorectal surgery will be enrolled.",[28],"2024-07-23",{"date":329,"type":36},"2024-07-24",{"date":331,"type":36},"2024-04-15",{"date":333,"type":20},"2025-09-25",{"name":335,"class":43},"IRCCS Ospedale San Raffaele",{"id":337,"slug":338,"hasResults":11,"nctId":339,"briefTitle":340,"officialTitle":340,"acronym":341,"eligibilityCriteria":342,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":343,"targetDuration":4,"studyType":76,"phases":4,"briefSummary":345,"conditions":346,"keywords":4,"overallStatus":304,"whyStopped":4,"lastUpdateSubmitDate":347,"lastUpdatePostDateStruct":348,"startDateStruct":350,"completionDateStruct":352,"leadSponsor":354,"locationsCount":4},"100416603","prospective-database-for-colonic-or-rectal-resection-surgery-patients-100416603","NCT04704817","Prospective Database for Colonic or Rectal Resection Surgery Patients","CHIRCOLREC","Inclusion Criteria:\n\n1. Patients treated for colonic and \u002F or rectal resection in the oncological digestive surgery department of the Paoli-Calmettes Institute,\n2. Patients over 18 years old,\n3. Affiliation to a social security scheme, or beneficiary of such a scheme.",{"count":344,"type":20},1000,"Colorectal cancer is the third most common cancer in men, after prostate and lung cancer. It represents 11.2% of all new cases of male cancer. In women, this cancer is the second most common after breast cancer (11.3% of all new cases of female cancer).",[28],"2021-01-08",{"date":349,"type":36},"2021-01-12",{"date":351,"type":20},"2021-03",{"date":353,"type":20},"2071-12",{"name":355,"class":43},"Institut Paoli-Calmettes"]