[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"colorectal-lesions\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:colorectal-lesions":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,49,78],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100598019","artificial-intelligence-assisted-colonoscopy-in-the-detection-and-characterization-of-colorectal-lesions-100598019",false,"NCT07066046","Artificial Intelligence-assisted Colonoscopy in the Detection and Characterization of Colorectal Lesions","Artificial Intelligence-assisted Colonoscopy in the Detection and Characterization of Colorectal Lesions: Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* All patients aged 18 years or older, with an elective indication for colonoscopy who sign the informed consent form agreeing to participate in the study.\n\nExclusion Criteria:\n\n* History of inflammatory bowel disease.\n* History of colorectal cancer.\n* Personal history of colorectal surgery.\n* Contraindication to endoscopic biopsies.\n* History of intestinal polyposis syndromes.\n* Urgent or emergency cases.\n* Presence of severe, decompensated comorbidities, or with a score of 3 or higher according to the American Society of Anesthesiologists (ASA) classification.\n* Incomplete colonoscopy that does not reach the cecum.\n* Insufficient or inadequate bowel preparation, with a score lower than 6 on the Boston Bowel Preparation Scale.\n* Patients who do not agree to participate in the study and do not sign the informed consent form (ICF).",true,"ALL","18 Years",{"count":20,"type":21},1000,"ESTIMATED","INTERVENTIONAL",[24],"NA","The study aims to evaluate the effectiveness of artificial intelligence-assisted colonoscopy in increasing adenoma detection rate and the accuracy in the characterization of colorectal lesions, compared to standard colonoscopy, in a randomized controlled clinical trial setting.",[27,28,29,30],"Colorectal Cancer (CRC)","Adenomatous Polyposis","Colorectal Lesions","Colorectal Cancer",[32,33,34,35],"Adenoma","Artificial Intelligence","Colonoscopy","Colorectal lesions","RECRUITING","2026-06-19",{"date":39,"type":40},"2026-06-23","ACTUAL",{"date":42,"type":40},"2025-02-01",{"date":44,"type":21},"2026-12-01",{"name":46,"class":47},"Instituto do Cancer do Estado de São Paulo","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":4},"100620226","effect-of-simplified-robot-faster-assisted-versus-conventional-endoscopic-submucosal-dissection-esd-for-colorectal-lesions-100620226","NCT07354867","Effect of Simplified Robot (FASTER) Assisted Versus Conventional Endoscopic Submucosal Dissection (ESD) for Colorectal Lesions","Effect of Simplified Robot (FASTER) Assisted Versus Conventional Endoscopic Submucosal Dissection (ESD) for Colorectal Lesions: A Prospective, Randomized, Controlled Trial","Inclusion Criteria:\n\n1. Age between 18 and 80 years.\n2. Patients with colorectal lesions scheduled to undergo endoscopic submucosal dissection (ESD)\n3. Lesion characteristics meeting any of the following criteria: (1) Lesions unsuitable for en bloc resection using snare-based EMR, including non-granular type laterally spreading tumors (LST-NG), especially pseudo-depressed subtype (PD); lesions with type VI pit pattern (VI-type glandular opening configuration); carcinomas with superficial submucosal invasion (T1-SM); large depressed-type tumors; large protruding lesions suspected of malignancy, including nodular mixed-type granular LSTs (LST-G); other lesions unsuitable for en bloc resection using snare-based EMR; (2) Lesions with special background conditions, including mucosal tumors with submucosal fibrosis (caused by prior biopsy or mucosal prolapse due to peristalsis); sporadic tumors arising in the context of chronic inflammation (e.g., ulcerative colitis); local residual or recurrent early carcinoma following prior endoscopic resection;\n4. Willingness to participate in the study and provision of written informed consent.\n\nExclusion Criteria:\n\n1. Suspected deep submucosal invasive carcinoma based on endoscopic features；\n2. Lesions presenting with non-lifting signs, suggesting deep submucosal invasive carcinoma or tumors with severe submucosal fibrosis;\n3. Lesions extending to the appendiceal orifice, colonic diverticulum, or ileocecal valve; (4) Pregnant women or women who may be pregnant; lactating women;\n4. Pregnant women or women who may be pregnant; lactating women;\n5. Patients with coagulation disorders;\n6. Patients considered ineligible for specific reasons;\n7. Patients with contraindications to anesthesia and\u002For colonoscopy. -","80 Years",{"count":58,"type":21},40,[24],"This study aims to compare the outcomes of Simplified Robot (FASTER) assisted Endoscopic Submucosal Dissection (ESD) with conventional ESD in the treatment of colorectal lesions. Using a prospective, single-center, randomized controlled design, the investigators will systematically evaluate differences between the two approaches in terms of total procedure time, mucosal dissection time and speed, resection quality (R0 resection rate and en bloc resection rate), incidence of complications (bleeding, perforation, muscularis injury), and the flexibility and clinical feasibility of robotic operation. The clinical significance of this study lies in assessing the value of robotic assistance in colorectal ESD, optimizing intraoperative workflow, reducing complication risks, improving patient outcomes and procedural efficiency, and providing evidence to support individualized therapeutic strategies in clinical practice.This study aims to compare the outcomes of Simplified Robot (FASTER) assisted Endoscopic Submucosal Dissection (ESD) with conventional ESD in the treatment of colorectal lesions. Using a prospective, single-center, randomized controlled design, the investigators will systematically evaluate differences between the two approaches in terms of total procedure time, mucosal dissection time and speed, resection quality (R0 resection rate and en bloc resection rate), incidence of complications (bleeding, perforation, muscularis injury), and the flexibility and clinical feasibility of robotic operation. The clinical significance of this study lies in assessing the value of robotic assistance in colorectal ESD, optimizing intraoperative workflow, reducing complication risks, improving patient outcomes and procedural efficiency, and providing evidence to support individualized therapeutic strategies in clinical practice.",[29,62,63],"Endoscopic Submucosal Dissection (ESD)","FASTER Robot",[62,35,65,66,67],"FASTER robot","Procedure time","Randomized controlled trial (RCT)","NOT_YET_RECRUITING","2026-01-12",{"date":71,"type":40},"2026-01-21",{"date":73,"type":21},"2026-01-06",{"date":75,"type":21},"2026-11-30",{"name":77,"class":47},"Kaiyun Liu",{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":48},"100590698","cold-snare-versus-cold-forceps-polypectomy-for-small-lesions-100590698","NCT06970808","Cold Snare Versus Cold Forceps Polypectomy for Small Lesions","Cold SNAre Versus Cold forcePS Polypectomy for Small Colorectal Lesions (Cold-SNAPS): a Multicenter Randomized Trial","Cold-SNAPS","Inclusion Criteria:\n\n* Patients aged ≥ 18 years;\n* Ability to provide informed consent;\n* Presence of at least one colorectal polypoid\u002Fnon-polypoid lesion \\\u003C 10 mm\n\nExclusion Criteria:\n\n* Primary or secondary coagulopathy;\n* Improper interruption of dual antiplatelet therapy and\u002For antiplatelet therapy with P2Y12 receptor antagonists (clopidogrel, prasugrel, ticagrelor) and\u002For anticoagulant therapy;\n* Chronic inflammatory bowel diseases;\n* Inpatients undergoing colonoscopy;\n* Colonoscopy as part of regional colorectal cancer screening;\n* Pregnancy or breastfeeding",{"count":87,"type":21},312,[24],"The goal of this clinical trial is to compare the efficacy and the safety of a new device for cold forceps polypectomy (CFP)- a special jumbo forceps- to cold snare polypectomy (CSP) for small colorectal lesions, without adding peri- or post-procedural risks to the patient.\n\nThe main questions it aims to answer are:\n\n* Does the cold forceps guarantee a complete endoscopic resection rate?\n* How many adverse events could the jumbo forceps reduce in comparison to CSP?\n* Does the lesion retrieval rate increase?\n* Does the polypectomy duration decrease? Participants will be randomized to one or to the other group when a polypoid or non-polypoid lesion is identified. If multiple polyps are found in the same patient, they will be removed using the same polypectomy technique.\n\nIf polypectomy cannot be performed using the indicated technique, a crossover will be done according to the best practice of care principles.",[91,29],"Colorectal Adenoma",[93,34,94],"Cold forceps polypectomy","Cold snare polypectomy","2025-05-06",{"date":97,"type":40},"2025-05-14",{"date":99,"type":21},"2025-12",{"date":101,"type":21},"2027-12",{"name":103,"class":47},"Azienda USL Modena"]