[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"common-warts-verruca-vulgaris\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:common-warts-verruca-vulgaris":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,45,69,96,136],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100643507","phase-3-cantharidin-application-in-patients-with-common-warts-verruca-vulgaris-cove-3-100643507",false,"NCT07637734","Cantharidin Application in Patients With Common Warts (Verruca Vulgaris) (COVE-3)","COVE-3: A Phase 3, Double-blind, Randomized, Vehicle-controlled Study to Evaluate the Efficacy and Safety of YCANTH (VP-102\u002FTO-208) in Subjects With Common Warts (Verruca Vulgaris)","COVE-3","Inclusion Criteria:\n\nCandidates will be included in the study if they:\n\n1. Are male or female patients ≥ 2 years of age.\n2. Are immunocompetent.\n3. Have a minimum of 1 treatable common wart (verruca vulgaris) of any size and height:\n\n   1. Common warts are considered treatable if they are located anywhere on the body, except for the following excluded areas: the eye area (including eyelids), lips, oral cavity, nasal cavity, inside of the ears, soles of the feet (plantar warts), subungual spaces (ie, under the fingernail or toenail), or the anogenital area (warts within 10 mm of a mucosal surface should not be treated).\n   2. Common warts located in excluded areas (warts within 10 mm of a mucosal surface) will not be treated or evaluated in this study. Warts that are genital, plantar, or anal are not considered common warts and are thus excluded from treatment and evaluation in this study. A subject will not be excluded from the study if they have these types of warts, but the subject must also have warts that meet the inclusion criteria. • If treatment of these excluded wart types is required during the study, it should be limited to destructive therapy such as cryosurgery and warts cannot be within 10 mm of any warts that are under study.\n4. Have no systemic or dermatologic disorder, which, in the opinion of the Investigator, will interfere with the study results or increase the risk of AEs.\n5. Agree to refrain from swimming, bathing, or prolonged immersion in water or any liquids until the study drug is removed after each treatment.\n6. Have the ability, or have a parent\u002Fguardian with the ability, to follow study instructions and the willingness to complete all study requirements.\n7. Agree not to use any wart-removing product (prescription or over-the-counter) other than the study drug during the course of the study, with the exception of circumstances allowed under Inclusion Criterion 3b.\n8. Provide written informed consent or assent in a manner approved by the IRB and\u002For have a parent\u002Fguardian provide written informed consent as evidenced by the signature on an IRB approved assent\u002Fconsent form. Subjects who turn 18 years of age (or legal age per state or country) during the study will be required to re-consent to remain on the study.\n9. Provide written authorization for use and disclosure of protected health information (per state and\u002For country requirements).\n10. If participating in the optional photographic assessment, agree to allow photographs of treatable common warts to be taken at selected visits by the research team.\n\nExclusion Criteria:\n\nCandidates will be excluded from the study if they:\n\n1. Are unable to cooperate with the requirements or visits of the study, as determined by the Investigator.\n2. Have any warts present at Baseline in an allowed anatomic location that the subject, parent\u002Fguardian, or Investigator is unwilling to treat.\n3. Plantar warts and external genital warts will not be included in this study, in addition, subungual warts and warts within 10 mm of a mucosal surface will not be included in this study due to their anatomical location and complex treatment modalities.\n4. Are systemically immunosuppressed or have taken required systemic immunosuppressive or immunomodulatory medication (including oral or parenteral corticosteroids) within 30 days before enrollment or such treatment is planned to be required during the course of the study. Routine use of local (eg, topical, inhaled, intranasal) corticosteroids and episodic use of systemic medications to treat conditions arising during the study is allowed.\n5. Have any chronic or acute medical condition that, in the opinion of the Investigator, may interfere with the study results or place the subject at undue risk (eg, human immunodeficiency virus, systemic lupus erythematosus, viral hepatitis, uncontrolled diabetes).\n6. Have had any previous treatment (including an investigational agent in a clinical trial) of common warts, including but not limited to the use of cantharidin, imiquimod, antivirals, retinoids, topical salicylic acid, lactic acid, hydrogen peroxide, trichloroacetic acid, pulse dye laser, iodine-based or nitric oxide-based therapies, oral cimetidine, coix seed, intralesional immunotherapy, curettage, or freezing of warts in the 30 days before treatment.\n7. Have more common warts, or wart area, to be treated than can be adequately covered with the contents of 2 study drug applicators, as determined by total wart surface area. Each applicator can cover approximately 1500 mm2 for a total of approximately 3000 mm2 using the 2 study drug applicators.\n8. Immunizations (eg, flu shots) may be administered throughout the study, but not within 5 days before or after any treatment with study drug and will be recorded as concomitant therapies in the eCRF.\n9. Have received any investigational product as part of a clinical trial NOT related to the treatment of common warts within 30 days before the first application of the study drug.\n10. Have epidermodysplasia verruciformis.\n11. Have an active malignancy or are undergoing treatment for any malignancy.\n12. Have a history or presence of clinically significant medical, psychiatric, or emotional condition or abnormality that, in the opinion of the Investigator, would compromise the safety of the subject or the quality of the data.\n13. Have a history or presence of hypersensitivity or an idiosyncratic reaction to the study drug or related compounds, or drug product excipients (acetone, ethyl alcohol, nitrocellulose, hydroxypropyl cellulose, castor oil, camphor, gentian violet, and denatonium benzoate).\n14. Have a condition or situation that may interfere significantly with the subject's participation in the study (eg, subjects who required hospitalization in the 2 months before screening for an acute or chronic condition including alcohol or drug abuse), as determined by the Investigator.\n15. Are sexually active or may become sexually active and are unwilling to practice a highly effective method of birth control (eg, combination of condoms and foam; oral contraceptives; intrauterine device with or without hormone release; transdermal, injectable, or intravaginal contraception). Withdrawal is not an acceptable method of birth control. Females who have reached menarche must have a negative urine pregnancy test at each visit before treatment with study drug.\n16. Are pregnant or breastfeeding.","ALL","2 Years",{"count":20,"type":21},300,"ESTIMATED","INTERVENTIONAL",[24],"PHASE3","This is a Phase 3, double-blind, randomized, vehicle-controlled study (Study number VP-CW-302; referred to as COVE-3 \\[Cantharidin and Occlusion in Verruca Epithelium\\]) to evaluate the efficacy and safety of YCANTH (VP-102\u002FTO-208) treatment in subjects with common warts.",[27,28,29,30],"Common Warts","Common Warts (Verruca Vulgaris)","Human Papilloma Virus (HPV)","Warts",[27,28,29],"NOT_YET_RECRUITING","2026-06-09",{"date":35,"type":36},"2026-06-10","ACTUAL",{"date":38,"type":21},"2026-06",{"date":40,"type":21},"2027-10",{"name":42,"class":43},"Verrica Pharmaceuticals Inc.","INDUSTRY",2,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":56,"conditions":57,"keywords":58,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":68},"100628152","phase-3-long-term-follow-up-study-of-cantharidin-ycanth-vp-102to-208-in-patients-with-common-warts-verruca-vulgaris-100628152","NCT07457918","Long-Term Follow-up Study of Cantharidin (YCANTH [VP-102\u002FTO-208]) in Patients With Common Warts (Verruca Vulgaris)","COVE-4: A Phase 3, Open-Label, Long-Term Follow-Up Study to Evaluate the Safety and Efficacy of YCANTH (VP-102\u002FTO-208) in Subjects With Common Warts (Verruca Vulgaris)","COVE-4","Inclusion Criteria:\n\nCandidates will be included in the study if they:\n\n1. Meet ≥ 1 of the following criteria:\n\n   1. Completed the Day 84 visit in the parent study and have ≥ 1 treatable common warts.\n   2. Completed the Day 105 visit in the parent study and have ≥ 1 treatable common warts.\n   3. Completed the Day 147 visit in the parent study.\n2. Provide written informed consent or assent in a manner approved by the Institutional Review Board (IRB) and\u002For have a parent\u002Fguardian provide written informed consent as evidenced by the signature on an IRB approved assent\u002Fconsent form. Subjects who turn 18 years of age (or legal age per state or country) during the study may be required to re consent to remain on the study (follow the state or country regulatory requirements).\n3. Agree to refrain from swimming, bathing, or prolonged immersion in water or any liquids until the study drug is removed after each treatment.\n4. Have the ability, or have a parent\u002Fguardian with the ability, to follow study instructions and the willingness to complete all study requirements.\n5. Agree not to use any wart-removing product (prescription or over-the-counter) other than the study drug during the course of the study with the exception of circumstances for excluded wart types. Excluded warts include common warts located in excluded areas that will not be treated or evaluated during the study as well as genital, plantar, or anal warts:\n\n   a. If treatment of these excluded wart types is required during the study, it should be limited to destructive therapy such as cryosurgery and warts cannot be within 10mm of any warts that are under study.\n6. Provide written authorization for use and disclosure of protected health information (per state and\u002For country requirements).\n7. If participating in the optional photographic assessment, agree to allow photographs of treatable common warts to be taken at selected visits by the research team.\n\nExclusion Criteria:\n\nCandidates will be excluded from the study if they:\n\n1. Are unable to cooperate with the requirements or visits of the study, as determined by the Investigator.\n2. Have any warts present at study entry in an allowed anatomic location that the subject, parent\u002Fguardian, or Investigator is unwilling to treat.\n3. Are systemically immunosuppressed or have taken required systemic immunosuppressive or immunomodulatory medication (including oral or parenteral corticosteroids) within 30 days before enrollment or such treatment is planned to be required during the course of the study. Routine use of local (eg, topical, inhaled, intranasal) corticosteroids and episodic use of systemic medications to treat conditions arising during the study is allowed.\n4. Have any chronic or acute medical condition that, in the opinion of the Investigator, may interfere with the study results or place the subject at undue risk (eg, human immunodeficiency virus, systemic lupus erythematosus, viral hepatitis, uncontrolled diabetes).\n5. Have had any previous treatment (including an investigational agent in a clinical trial) of common warts, including but not limited to the use of cantharidin, imiquimod, antivirals, retinoids, topical salicylic acid, lactic acid, hydrogen peroxide, trichloroacetic acid, pulse dye laser, iodine-based or nitric oxide-based therapies, oral cimetidine, coix seed, intralesional immunotherapy, curettage, or freezing of warts in the 30 days before treatment.\n6. Immunizations (eg, flu shots) may be administered throughout the study, but not within 5 days before or after any treatment with study drug.\n7. Have received any investigational product as part of a clinical trial NOT related to the treatment of common warts within 30 days before the first application of the study drug.\n8. Have epidermodysplasia verruciformis.\n9. Have an active malignancy or are undergoing treatment for any malignancy.\n10. Have a clinically significant medical, psychiatric, emotional condition, or abnormality that, in the opinion of the Investigator, would compromise the safety of the subject or the quality of the data.\n11. Have a hypersensitivity or an idiosyncratic reaction to YCANTH (VP-102\u002FTO-208) or related compounds, or drug product excipients (acetone, ethyl alcohol, nitrocellulose, hydroxypropyl cellulose, castor oil, camphor, gentian violet, and denatonium benzoate).\n12. Have a condition or situation that may interfere significantly with the subject's participation in the study (eg, subjects who require hospitalization for an acute or chronic condition including alcohol or drug abuse), at the determination of the Investigator.\n13. Are sexually active or may become sexually active and are unwilling to practice responsible birth control methods (eg., combination of condoms and foam, birth control pills, intrauterine device, patch, shot and vaginal ring). Withdrawal is not an acceptable method of birth control. Females who have reached menarche must have a negative urine pregnancy test at each visit before treatment with YCANTH (VP-102\u002FTO-208).\n14. Are pregnant or breastfeeding.",{"count":54,"type":21},600,[24],"People who participated in either the COVE-2 or COVE-3 study for common warts, may be eligible to enroll into this Long Term Follow Up (LTFU) study COVE-4. The main question(s) to answer in this LTFU study are:\n\n* To assess the safety of YCANTH (also known as VP-102 in the United Sates or TO-208 in Japan) by assessing concomitant medication use, and adverse events (AEs), including expected local skin reactions (LSRs).\n* To evaluate the efficacy of continued skin application of YCANTH (VP-102\u002FTO-208) when applied to each common wart once every 21 days for a maximum of 4 additional treatments.\n\nParticipants with eligible common warts present will receive YCANTH (VP-102\u002FTO-208) with an interval of 21 (± 4) days between applications until there is a wart count of zero (ie, completed clearance has been achieved) or a maximum of 4 additional treatments. Participants with complete clearance will attend Observation Visits at intervals of 42 (± 4) days without treatment. Participants who develop a new wart after having a wart count of zero will resume Treatment Visits every 21 (± 4) days for a maximum of 4 additional treatments. All subjects will attend visits until the End-of-Study (EOS) Visit, which is on Day 378 (0\u002F+ 8 days).\n\nIf participants still have warts present after 4 additional treatments of YCANTH (VP-102\u002FTO-208) the wart(s) will be discontinued from study and participants will be allowed to seek treatment but should be limited to destructive therapy such as cryosurgery and warts cannot be within 10 mm of any warts that receive(d) study drug treatment . The exact interval of Treatment Visits will be determined by evaluation of the treatment site, taking into account any ongoing local skin reactions (LSRs), which are defined as temporary application site:\n\nvesiculation, pain, pruritus, scabbing, erythema, discoloration, dryness, edema and erosion that is expected and consistent with historical treatment with YCANTH (VP-102\u002FTO-208). Participants may receive treatment until all treatable common warts are clear, up to a maximum of 4 treatment sessions, or until Day 357, whichever occurs first.\n\nTreatment:\n\nFor participants with warts present at the time of study entry, the first treatment application may occur on the same day as transition from the parent study. All required parent study assessments must be complete, including the final evaluation of response to treatment (ERT; as defined in Assessments and procedures).\n\nIn addition, eligibility for participation in the LTFU study must have been determined, and informed consent\u002Fassent for participation in this LTFU study obtained. YCANTH (VP-102\u002FTO-208) will be applied by the Investigator or qualified member of the research team to treatable common warts, including an approximate 1 to 2 mm margin of healthy, surrounding skin. After YCANTH (VP-102\u002FTO- 208) is applied, warts are to be covered with occlusive tape (occlusive tape with similar properties should be used across all clinical sites) that will remain in place overnight and should be removed 24 hours after application of study drug and just before a 24-hour ERT. Before application of study drug, wart paring, if necessary, will be completed with a sharp surgical instrument (eg, scalpel or flexible medical blade) to remove any adherent thick scale from a treatable common wart. Wart paring is required to be performed at any treatment visit when adherent thick scale is present, and the Investigator feels paring can be safely performed. Paring should be conducted by a trained practitioner and in compliance with any local regulations and should be discontinued if it results in punctate bleeding or significant pain. Not all treatable common warts may require paring. If adherent scale is not present, study drug can be applied without paring. The assessment for complete clearance may be made once all treatable common warts are evaluable and not obscured by an ongoing LSR. If the Investigator is unable to evaluate or treat 1 or more warts due to ongoing LSRs, no warts should be treated, and the visit will be documented as an Unscheduled Visit. The timing of the next treatment visit will be determined by resolution of the LSRs. The research team will be in contact with the Participant until all LSRs are resolved. Once LSRs have resolved, a Treatment Visit will be scheduled within 21 (± 4) days of the previous treatment application, noting it may be longer than 21 (± 4) days depending on the length of time until LSR resolution. All treatable common warts that are not completely clear should undergo treatment with study drug. Study duration from Days 84, 105, or 147 of the parent study (COVE-2 or COVE-3) through the final EOS visit of this LTFU study (Day 378) is approximately 294 days.",[28,27,29,30],[28,27,29],"RECRUITING","2026-04-30",{"date":62,"type":36},"2026-05-05",{"date":64,"type":36},"2026-03-11",{"date":66,"type":21},"2028-05-22",{"name":42,"class":43},4,{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":17,"minAge":76,"maxAge":4,"enrollmentInfo":77,"targetDuration":4,"studyType":22,"phases":79,"briefSummary":81,"conditions":82,"keywords":83,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":95},"100634764","new-treatment-of-common-wart-100634764","NCT07543926","New Treatment of Common Wart","Evaluation Of Intralesional Platelet-Rich Fibrin Versus Intralesional Vitamin D In Treatment Of Common Warts","Inclusion Criteria:\n\n* \\- Age more than or equal to 18 years\n* Clinically and dermoscopically confirmed Common warts of both sex\n* patient not receiving previous treatment at least one month before recruitment in our study\n* Single or multiple lesions suitable for injection.\n\nExclusion Criteria:\n\n* Chronic Systemic desise (DM , HTN , Autoimmune , immunosuppressive disorders eg , lupus , renal or hepatic failure ) or Hematologic Conditions (anemia : hemoglobin level below 10 g\u002Fdl , thrombocytopenia : platelet count below 150,000 \u002FµL ) Infectious Diseases , Local bacterial or fungal infection at the lesions .\n\nPregnancy, Lactation , patients who has hypersensitivity of vitamin D .","18 Years",{"count":78,"type":21},70,[80],"NA","this study aims to compare the efficacy and safety of platelet rich fibrin injection versus intralesional vitamin D injection in the treatmentof common warts. PRF, as an autologous biological material , may enhance tissue regeneration and immune response.",[28],[84],"PRF injection","2026-04-18",{"date":87,"type":36},"2026-04-22",{"date":89,"type":21},"2026-04-06",{"date":91,"type":21},"2026-12-30",{"name":93,"class":94},"Sohag University","OTHER",1,{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":100,"acronym":4,"eligibilityCriteria":101,"healthyVolunteers":11,"sex":17,"minAge":102,"maxAge":4,"enrollmentInfo":103,"targetDuration":4,"studyType":22,"phases":105,"briefSummary":107,"conditions":108,"keywords":116,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":44},"100627454","phase-4-intralesional-therapies-for-cutaneous-viral-warts-a-comparative-analysis-of-vitamin-d3-and-acyclovir-100627454","NCT07448844","Intralesional Therapies For Cutaneous Viral Warts: A Comparative Analysis Of Vitamin D3 And Acyclovir","Inclusion Criteria:\n\n* Patients aged 12 years and above with clinically diagnosed cutaneous warts\n* Common, plantar, flat, or periungual warts\n* Both treatment-naïve patients and those with recalcitrant warts\n\nExclusion Criteria:\n\n* Pregnant or lactating women\n* Immunocompromised patients\n* Individuals with history of hypersensitivity to vitamin D3 or acyclovir\n* Individuals receiving systemic immunosuppressive or antiviral therapy\n* Patients with secondary infection at injection site\n* Patients who had received any topical or destructive treatment for wart in previous three months","12 Years",{"count":104,"type":21},40,[106],"PHASE4","The goal of this clinical trial is to learn if injecting acyclovir (an antiviral drug) or vitamin D3 directly into skin warts works to clear them in people aged 12 and older with common, plantar, flat, or periungual (around the nail) warts. The main questions it aims to answer are:\n\n1. Does intralesional acyclovir or vitamin D3 lead to complete clearance of warts by week 8?\n2. Which treatment clears warts more effectively?\n3. What side effects do participants have with each treatment?\n\nResearchers will compare acyclovir injections (Group A) to vitamin D3 injections (Group B), with 20 participants in each group, to see which treatment works better at clearing warts.\n\nParticipants will:\n\n1. Receive an injection directly into the wart every 2 weeks for up to 4 sessions\n2. Have photographs taken of their warts before treatment and at each visit\n3. Visit the clinic for checkups where the size and number of warts will be measured\n4. Be followed for up to 3 months to check for wart recurrence and side effects",[109,110,28,111,112,113,114,115],"Viral Wart","Plantar Wart","Common Wart","Flat Wart","Warts of Foot","Warts Hand","Wart",[117,118,119,120,121,122,123,124,125,126],"Cutaneous warts","intralesional therapy","treatment efficacy","plantar warts","common warts","human papillomavirus","randomized controlled trial","vitamin D3","acyclovir","flat warts","2026-03-06",{"date":129,"type":36},"2026-03-10",{"date":131,"type":36},"2026-02-20",{"date":133,"type":21},"2026-05-20",{"name":135,"class":94},"Riphah International University",{"id":137,"slug":138,"hasResults":11,"nctId":139,"briefTitle":140,"officialTitle":141,"acronym":142,"eligibilityCriteria":143,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":144,"targetDuration":4,"studyType":22,"phases":145,"briefSummary":146,"conditions":147,"keywords":148,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":157},"100611900","phase-3-cantharidin-application-in-patients-with-common-warts-verruca-vulgaris-cove-2-100611900","NCT07246590","Cantharidin Application in Patients With Common Warts (Verruca Vulgaris) (COVE-2)","COVE-2: A Phase 3, Double-blind, Randomized, Vehicle-controlled Study to Evaluate the Efficacy and Safety of YCANTH (VP-102) in Subjects With Common Warts (Verruca Vulgaris)","COVE-2","Inclusion Criteria:\n\nCandidates will be included in the study if they:\n\n1. Are male or female patients ≥ 2 years of age.\n2. Are immunocompetent.\n3. Have a minimum of 1 treatable common wart (verruca vulgaris) of any size and height:\n\n   1. Common warts are considered treatable if they are located anywhere on the body, except for the following excluded areas: the eye area (including eyelids), lips, oral cavity, nasal cavity, inside of the ears, soles of the feet (plantar warts), subungual spaces (ie, under the fingernail or toenail), or the anogenital area (warts within 10 mm of a mucosal surface should not be treated).\n   2. Common warts located in excluded areas (warts within 10 mm of a mucosal surface) will not be treated or evaluated in this study. Warts that are genital, plantar, or anal are not considered common warts and are thus excluded from treatment and evaluation in this study. A subject will not be excluded from the study if they have these types of warts, but the subject must also have warts that meet the inclusion criteria.\n\n      * If treatment of these excluded wart types is required during the study, it should be limited to destructive therapy such as cryosurgery and warts cannot be within 10 mm of any warts that are under study.\n4. Have no systemic or dermatologic disorder, which, in the opinion of the Investigator, will interfere with the study results or increase the risk of AEs.\n5. Agree to refrain from swimming, bathing, or prolonged immersion in water or any liquids until the study drug is removed after each treatment.\n6. Have the ability, or have a parent\u002Fguardian with the ability, to follow study instructions and the willingness to complete all study requirements.\n7. Agree not to use any wart-removing product (prescription or over-the-counter) other than the study drug during the course of the study, with the exception of circumstances allowed under Inclusion Criterion 3b.\n8. Provide written informed consent or assent in a manner approved by the IRB and\u002For have a parent\u002Fguardian provide written informed consent as evidenced by the signature on an IRB approved assent\u002Fconsent form. Subjects who turn 18 years of age (or legal age per state or country) during the study will be required to re-consent to remain on the study.\n9. Provide written authorization for use and disclosure of protected health information (per state and\u002For country requirements).\n10. If participating in the optional photographic assessment, agree to allow photographs of treatable common warts to be taken at selected visits by the research team.\n\nExclusion Criteria:\n\nCandidates will be excluded from the study if they:\n\n1. Are unable to cooperate with the requirements or visits of the study, as determined by the Investigator.\n2. Have any warts present at Baseline in an allowed anatomic location that the subject, parent\u002Fguardian, or Investigator is unwilling to treat.\n3. Plantar warts and external genital warts will not be included in this study, in addition, subungual warts and warts within 10 mm of a mucosal surface will not be included in this study due to their anatomical location and complex treatment modalities.\n4. Are systemically immunosuppressed or have taken required systemic immunosuppressive or immunomodulatory medication (including oral or parenteral corticosteroids) within 30 days before enrollment or such treatment is planned to be required during the course of the study. Routine use of local (eg, topical, inhaled, intranasal) corticosteroids and episodic use of systemic medications to treat conditions arising during the study is allowed.\n5. Have any chronic or acute medical condition that, in the opinion of the Investigator, may interfere with the study results or place the subject at undue risk (eg, human immunodeficiency virus, systemic lupus erythematosus, viral hepatitis, uncontrolled diabetes).\n6. Have had any previous treatment (including an investigational agent in a clinical trial) of common warts, including but not limited to the use of cantharidin, imiquimod, antivirals, retinoids, topical salicylic acid, lactic acid, hydrogen peroxide, trichloroacetic acid, pulse dye laser, iodine-based or nitric oxide-based therapies, oral cimetidine, coix seed, intralesional immunotherapy, curettage, or freezing of warts in the 90 days before treatment.\n7. Have more common warts, or wart area, to be treated than can be adequately covered with the contents of 2 study drug applicators, as determined by total wart surface area. Each applicator can cover approximately 1500 mm2 for a total of approximately 3000 mm2 using the 2 study drug applicators.\n8. Immunizations (eg, flu shots) may be administered throughout the study, but not within 5 days before or after any treatment with study drug and will be recorded as concomitant therapies in the eCRF.\n9. Have received any investigational product as part of a clinical trial NOT related to the treatment of common warts within 30 days before the first application of the study drug.\n10. Have epidermodysplasia verruciformis.\n11. Have an active malignancy or are undergoing treatment for any malignancy.\n12. Have a history or presence of clinically significant medical, psychiatric, or emotional condition or abnormality that, in the opinion of the Investigator, would compromise the safety of the subject or the quality of the data.\n13. Have a history or presence of hypersensitivity or an idiosyncratic reaction to the study drug or related compounds, or drug product excipients (acetone, ethyl alcohol, nitrocellulose, hydroxypropyl cellulose, castor oil, camphor, gentian violet, and denatonium benzoate).\n14. Have a condition or situation that may interfere significantly with the subject's participation in the study (eg, subjects who required hospitalization in the 2 months before screening for an acute or chronic condition including alcohol or drug abuse), as determined by the Investigator.\n15. Are sexually active or may become sexually active and are unwilling to practice a highly effective method of birth control (eg, combination of condoms and foam; oral contraceptives; intrauterine device with or without hormone release; transdermal, injectable, or intravaginal contraception). Withdrawal is not an acceptable method of birth control. Females who have reached menarche must have a negative urine pregnancy test at each visit before treatment with study drug.\n16. Are pregnant or breastfeeding.",{"count":20,"type":21},[24],"This is a Phase 3, double-blind, randomized, vehicle-controlled study (Study number VP-CW-301; referred to as COVE-2 \\[Cantharidin and Occlusion in Verruca Epithelium\\]) to evaluate the efficacy and safety of YCANTH (VP-102) treatment in subjects with common warts.",[27,28,29,30],[27,28,29],"2026-01-19",{"date":151,"type":36},"2026-01-21",{"date":153,"type":36},"2025-12-17",{"date":155,"type":21},"2027-06",{"name":42,"class":43},6]