[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"communication-nonverbal\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:communication-nonverbal":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,83],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100622479","phase-1-enhancing-orthographic-communication-and-literacy-outcomes-for-aac-learners-100622479",false,"NCT07384156","Enhancing Orthographic Communication and Literacy Outcomes for AAC Learners","Enhancing Orthographic Communication and Literacy Outcomes for AAC Learners: Investigating Effective Instructional Strategies","Inclusion Criteria:\n\n* Have complex communication needs and use AAC,\n* are ages 5-12,\n* per report can follow two-step directions,\n* symbolic communicators with at least 75 words on the CDI and mean length of utterance greater than 2\n* can match letters and words with greater than 90% accuracy,\n* can identify letter-sound correspondences from a field of 4 with greater than 70% accuracy\n* can identify common photographs used to represent words in the study (e.g., touch the picture of a hat, touch hot) with greater than 80% accuracy,\n* can sit to work in a minimum of 5 min. intervals\n* decoding or encoding at less than 40% accuracy based on parent or provider report and screening results;\n* demonstrate functional vision and hearing\n\nExclusion Criteria:\n\n* • Do not have complex communication needs \u002F can speak and do not need AAC,\n\n  * Younger than 5 or older than 12 years of age,\n  * Can not follow two-step directions,\n  * Are not symbolic communicators with at least 75 words on the CDI and not combining at least 2 symbols\n  * Can not match letters and words with \\>90% accuracy,\n  * Can not identify letter-sound correspondences from a field of 4 with greater than 70% accuracy\n  * Can not identify common photographs used to represent words in the study (e.g., touch the picture of a hat, touch hot) with greater than 80% accuracy,\n  * Can not attend to work for 5 mins.\n  * decoding or encoding at more than 40% accuracy based on parent or provider report and screening results;\n  * Do not have corrected or functional vision and hearing","ALL","5 Years","12 Years",{"count":20,"type":21},60,"ESTIMATED","INTERVENTIONAL",[24,25],"PHASE1","PHASE2","The goal of this clinical trial is to determine whether adding Integrated Decoding and Encoding instruction to the ALLSTAR literacy program improves reading outcomes for students with significant literacy and communication needs. The study will also examine how students' reading skills change over time across instructional conditions.\n\nThe main questions it aims to answer are:\n\nDo students who receive ALLSTAR with Integrated Decoding and Encoding instruction demonstrate greater improvements in literacy outcomes than students who receive ALLSTAR as standard care alone? How do students' literacy skills change from baseline to mid-intervention and post-intervention across the two instructional conditions? Researchers will compare two groups using a randomized controlled trial design. One group will receive 60 lessons of ALLSTAR as the standard of care (ALLSTAR-SC), and the other group will receive 60 lessons of ALLSTAR with the addition of Integrated Decoding and Encoding lessons (ALLSTAR-I\\*). Literacy outcomes will be measured using repeated assessment probes at baseline (0 Lessons), after 30-40 lessons, and after 60 lessons to evaluate differences between groups and changes over time in the individuals.",[28,29],"Literacy","Communication, Nonverbal",[31,32,33,34,35,36],"literacy","augmentative and alternative communication","nonverbal","Communication","Autism","Intellectual Disabilities","NOT_YET_RECRUITING","2026-01-26",{"date":40,"type":41},"2026-02-03","ACTUAL",{"date":43,"type":21},"2026-03-01",{"date":45,"type":21},"2031-02-28",{"name":47,"class":48},"Penn State University","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":62,"conditions":63,"keywords":68,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":82},"100614357","harnessing-communication-preferences-100614357","NCT07278544","Harnessing Communication Preferences","Harnessing Communication Preferences to Enhance Its Persistence and Mitigate Relapse of Challenging Behavior","Inclusion Criteria:\n\n* 2 years old and older.\n* Diagnosis of intellectual or developmental disability.\n* Referred for assessment and treatment of challenging behavior.\n\nExclusion Criteria:\n\n* Challenging behavior does not occur within the context of structured assessment, eliminating the ability to identify its operant function, or the behavior is deemed too dangerous to safely observe during assessment.\n* Communicate functionally using vocal\u002Fverbal communication.\n* Can only identify one proficient AAC strategy.","2 Years","90 Years",{"count":20,"type":21},[61],"NA","The goal of this clinical trial is to evaluate how preference for communication approach (e.g., using a touch talker versus picture cards) impacts treatment maintenance in the context of treatment to reduce challenging behavior exhibited by individuals with intellectual and\u002For developmental disabilities. As well, the clinical trial will evaluate how this preference impacts treatment relapse when care providers implement intervention and will identify potential demographic variables (e.g., age and symptom severity) that affect outcomes.\n\nThe main question\\[s\\] it aims to answer \\[is\u002Fare\\]:\n\nPreferred communication strategies will persist to a greater extent when intervention is disrupted, relative to less preferred communication strategies.\n\nCommunication modality preference will increase persistence for individuals with lower pre-experimental symptom severity scores and higher pre-experimental communication functioning scores. We predict demographic characteristics and developmental level will not impact intervention outcomes.\n\nTwo groups will be compared. Group 1 will receive initial intervention using a preferred communication strategy. Group 2 will receive initial intervention using a non preferred, but effective, communication strategy. Intervention type will then be reversed. Researchers will compare preferred and non preferred interventions on continued expression of the communication strategy when intervention is challenged.\n\nParticipants will exhibit alternative appropriate communicative behavior as a means of replacing\u002Freducing challenging behavior. This will take place using (a) preferred communication strategies and (b) non preferred communication strategies. Following successful intervention with each type of communication, intervention will be challenged and continued use of the communication strategy will be measured.",[64,65,66,67,29],"Intellectual Disability","Autism Spectrum Disorder","Self-Injurious Behavior","Communication Disabilities",[69,70,71],"Functional communication training","Treatment maintenance","Behavioral relapse","RECRUITING","2025-12-03",{"date":75,"type":41},"2025-12-12",{"date":77,"type":41},"2025-08-15",{"date":79,"type":21},"2031-03-31",{"name":81,"class":48},"Joel E. Ringdahl",2,{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":90,"enrollmentInfo":91,"targetDuration":4,"studyType":22,"phases":93,"briefSummary":94,"conditions":95,"keywords":96,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":82},"100495982","heart-rate-informed-changes-in-care-for-non-communicating-patients-100495982","NCT05738278","Heart Rate Informed Changes in Care for Non-Communicating Patients","Heart Rate Informed Changes in Care for Non-Communicating Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Between 5 and 70 years of age at the time of data collection\n* Autism spectrum disorder as evaluated by clinical psychologist\n* Communication difficulties\n* Living at a care home with round-the-clock staff for at least five days a week; or attending one-to-one staffed school\u002Fday-care at least five days a week.\n* Written informed consent is obtained from the subjects' legal representative.\n\nExclusion Criteria:\n\n\\- Having any autoimmune disorder or any type of cancer with ongoing chemotherapy.","70 Years",{"count":92,"type":21},38,[61],"The overarching aim is to generate knowledge to reduce incidence of pain in non-verbal patients' everyday life. The trial will 1) evaluate how HR can be used to identify potentially painful care procedures that should be re-evaluated in terms of the approach taken; 2) test the effect of heart rate (HR)-informed changes in potentially painful care procedures on biomarkers of pain, and 3) assess how six weeks of communication through HR affects the quality of communication between patient and caregiver.",[65,64,29],[97,98,64,99,100,101,34,102,103],"Heart Rate","Autistic Disorder","Social Interaction","Caregivers","Developmental Disabilities","Biomarkers","Pain","2025-07-01",{"date":106,"type":41},"2025-07-04",{"date":108,"type":41},"2023-02-27",{"date":110,"type":21},"2025-12-30",{"name":112,"class":48},"University of Oslo"]