[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"community-pharmacy-services\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:community-pharmacy-services":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,55],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100621657","an-evaluation-of-the-impact-of-pharmacist-comprehensive-medication-management-with-pharmacogenomic-results-to-improve-depression-outcomes-in-community-pharmacies-100621657",false,"NCT07373470","An Evaluation of the Impact of Pharmacist Comprehensive Medication Management With Pharmacogenomic Results to Improve Depression Outcomes in Community Pharmacies.","Genotype-guided Comprehensive Medication Management to Improve Depression Outcomes in Pennsylvania","COMPASS-PGx","INCLUSION CRITERIA:\n\n* At targeted community pharmacy for:\n\n  * New prescription or change in dose\u002Fschedule of SSRI (citalopram, escitalopram, sertraline, paroxetine), OR\n  * Concurrent SSRI (citalopram, escitalopram, sertraline, paroxetine) and new prescription\u002Fchange in SNRI (desvenlafaxine, duloxetine, and venlafaxine) \u002F bupropion.\n* Depressive symptoms confirmed by PHQ8 assessment (\\>5 indicating at least mild depressive symptoms)\n* UPMC patient (or able\u002Fwilling to become one) and has UPMC provider (or able\u002Fwilling to obtain one)\n* Signed consent to join Pitt+Me Discovery biobanking research study.\n* English-speaking\n\nEXCLUSION CRITERIA:\n\n* Inability to receive CMM at specific pharmacy\u002Fpharmacist\n* Comorbid diagnosis of schizophrenia (patient-reported)\n* Untreated sleep disorder (patient-reported)\n* Pitt+Me Discovery participant who has elected to not receive return of results, or who has already received results previously","ALL","18 Years",{"count":20,"type":21},220,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this prospective, randomized clinical trial is to learn whether pharmacogenomic (PGx)-guided comprehensive medication management delivered by pharmacists in community pharmacies will improve antidepressant treatment outcomes.\n\nThe primary aim is to determine whether comprehensive medication management with review of PGx testing results improves depression symptoms, compared with usual care.\n\nParticipants 18 years of age or older who have undergone PGx testing (e.g. through an independent biobanking study (Pitt+Me Discovery) who require initiation or adjustment of antidepressant therapy will be randomly assigned to receive either PGx-guided comprehensive medication management or usual care. Those who receive usual care will receive their PGx results at the end of the study. Researchers will compare the groups to assess whether PGx-guided care provided in partnership with community pharmacists and prescribers results in better depression and medication outcomes.",[27,28,29,30],"Pharmacogenetics","Depression - Major Depressive Disorder","Pharmacogenomic Drug Interaction","Community Pharmacy Services",[32,33,34,35,36,37,38,39,40,41],"precision medicine","pharmacogenomics","PGx","Comprehensive medication management","pharmacist","community pharmacy","medication review","antidepressants","pharmacogenomic testing","management of depression","NOT_YET_RECRUITING","2026-04-06",{"date":45,"type":46},"2026-04-08","ACTUAL",{"date":48,"type":21},"2026-04",{"date":50,"type":21},"2026-12-31",{"name":52,"class":53},"University of Pittsburgh","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":4,"eligibilityCriteria":61,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":22,"phases":65,"briefSummary":66,"conditions":67,"keywords":68,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":54},"100545146","evaluation-of-the-effect-of-consensus-based-protocols-for-the-treatment-of-minor-ailments-100545146","NCT06378099","Evaluation of the Effect of Consensus-based Protocols for the Treatment of Minor Ailments","Evaluation of the Effect of Consensus-based Protocols for the Treatment of Minor Ailments in Drugstores and Pharmacies in Medellin and the Metropolitan Area, Colombia: A Randomized Clinical Trial.","Inclusion Criteria:\n\nDrugstores and drugstores\u002Fpharmacies:\n\n* Establishments located in Medellin and Metropolitan area\n* Establishments that have a Pharmacy Technician serving as the technical director.\n* Establishments with electronic point-of-sale system for data collection.\n* Commitment to participate for the full 10-month study period.\n\nParticipants (patients):\n\n* Explicit consent to participate in the study.\n* Are the direct consumers requesting the nonprescription drug (i.e., not requesting them on behalf of someone else).\n* Present one of the five predefined potential MA that will be included in the study: influenza-like syndrome and catarrh, headache, common cold, sore throat, and menstrual pain or cramps.\n* Have access to mobile phone for follow-upThe person requesting the OTC medication must be the end consumer of it.\n\nExclusion Criteria:\n\n* Subjects who refuse to sign the informed consent\n* Subjects with an evident incapacity to complete the data questionnaire\n* Pregnant or breastfeeding women\n* Patients whose MA result from an ADR\n* Patients with symptoms lasting more than seven days","65 Years",{"count":64,"type":21},900,[24],"Minor ailments are common, self-limited conditions unrelated to the patient's underlying health problems or adverse effects of their current medications. Minor ailment services are pharmacist-led interventions that provide patients with the most appropriate recommendation when unsure about the medication for a specific minor ailment. It involves advice on nonprescription drugs, non-pharmacological measures, or referral to another health care practitioner. In Colombia, evaluating and implementing this service could optimize nonprescription drugs use and improve minor ailment management in primary health care settings.",[30],[69,70,71,72,73,74,75,76,77],"Minor ailments","Minor Ailment Services","Pharmacies","Nonprescription drugs","Pharmacy Technicians","Health education","Self care","Ambulatory care","Community Health Services","RECRUITING","2025-08-27",{"date":81,"type":46},"2025-08-29",{"date":83,"type":46},"2024-12-04",{"date":85,"type":21},"2025-10",{"name":87,"class":53},"Universidad de Antioquia"]