[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"complete-edentulism\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:complete-edentulism":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,47,69,85,114,136,166,190,223,251],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100053606","clinical-performance-and-quality-of-life-of-3d-printed-complete-dentures-under-digital-vs-hybrid-workflows-a-randomized-crossover-trial-100053606",false,"NCT07626827","Clinical Performance and Quality of Life of 3D-Printed Complete Dentures Under Digital vs Hybrid Workflows: A Randomized Crossover Trial","Clinical Success, Oral Health-Related Quality of Life, and Relationship Between Maximum Masticatory Force and Denture Wear in Complete Dentures Fabricated by Additive Manufacturing Under Digital and Hybrid Workflows: A Prospective Randomized Crossover Clinical Trial","PRINT-DENT","Inclusion Criteria:\n\n* Completely edentulous (bimaxillary)\n* Age between 50 and 90 years\n* Able to understand and sign informed consent\n* No cognitive or psychological deficits that interfere with study participation\n\nExclusion Criteria:\n\n* Unimaxillary edentulism\n* Presence of Kelly syndrome\n* Presence of flabby tissue on alveolar ridges\n* No prior experience with complete dentures\n* Chronic motor disorders that may compromise prosthetic function","ALL","50 Years","90 Years",{"count":21,"type":22},20,"ESTIMATED","INTERVENTIONAL",[25],"NA","This prospective randomized crossover clinical trial evaluates and compares the clinical performance and oral health-related quality of life (OHRQoL) of complete dentures fabricated through two additive manufacturing workflows - digital and hybrid - in edentulous patients attending the Dental Clinic of Universidad de Especialidades Espíritu Santo (UEES), Samborondón, Ecuador.\n\nIn the digital workflow, complete dentures are fabricated using direct intraoral scanning of edentulous ridges, CAD design, and 3D printing. In the hybrid workflow, conventional functional impressions are digitized, followed by CAD design and additive manufacturing of the definitive dentures.\n\nEach eligible participant receives two complete denture sets in a randomized crossover sequence (no washout period): Denture Set 1 is worn for 2 months, after which the participant crosses over to Denture Set 2, worn for an additional 2 months. Total active follow-up per participant is approximately 4 months. Following completion of the crossover phase, denture wear is monitored longitudinally for 12 months from the insertion of the second denture set (total study duration approximately 16 months per participant).\n\nThe study addresses three specific objectives:\n\nTo determine the clinical success rate of complete dentures fabricated by additive manufacturing under digital and hybrid workflows, evaluating retention, stability, denture base adaptation, occlusal balance, and need for clinical adjustments.\n\nTo evaluate the impact of complete denture treatment on OHRQoL using the validated OHIP-EDENT questionnaire, assessed at the insertion of each denture set and at the 2-month control of each period (4 measurement points total).\n\nTo evaluate the relationship between maximum masticatory force (T-Scan digital occlusal analysis system) and denture wear (volumetric 3D digital metrology via STL superimposition), with wear monitored over 12 months from insertion of the second denture set.",[28],"Complete Edentulism",[30,31,32,33],"hybrid workflow","complete denture","digital workflow","complete edentulous","RECRUITING","2026-07-09",{"date":37,"type":38},"2026-07-13","ACTUAL",{"date":40,"type":38},"2026-07-01",{"date":42,"type":22},"2027-11-30",{"name":44,"class":45},"Universidad de Especialidades Espiritu Santo","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":4,"studyType":23,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":46},"100641462","prosthetic-complications-in-full-arch-screw-retained-implant-restorations-using-monolithic-zirconia-versus-titanium-frameworks-a-randomized-clinical-trial-100641462","NCT07657364","Prosthetic Complications in Full-arch Screw-retained Implant Restorations Using Monolithic Zirconia Versus Titanium Frameworks: A Randomized Clinical Trial","Inclusion Criteria:\n\n1. Aged 18 years or older.\n2. Able to understand the study procedures and provide written informed consent.\n3. In good general health, classified as American Society of Anesthesiologists (ASA) Physical Status Class I or II.\n4. Completely edentulous in the arch to be treated (maxilla and\u002For mandible).\n5. A candidate for a full-arch, screw-retained implant-supported prosthesis, requiring 4 to 6 implants in the treatment arch.\n6. Sufficient bone volume at planned implant sites to place implants of at least 3.5mm in diameter and 8mm in length.\n7. Adequate crown height space (15-22 mm) for a fixed prosthesis.\n8. A zone of keratinized mucosa at the crest of the ridge measuring at least 2 mm in width.\n9. Opposing arch is fixed full-arch implant-supported prosthesis.\n10. Demonstrates acceptable oral hygiene and the motivation to maintain it.\n\nExclusion Criteria:\n\n1. Medical contraindications:\n\n   * Uncontrolled diabetes (HbA1c \\> 7.0%).\n   * History of radiotherapy in the head and neck region.\n   * History of intravenous bisphosphonate therapy.\n   * Immunosuppressed or immunocompromised status.\n   * Any other uncontrolled systemic disease that constitutes a contraindication for oral surgery.\n2. Behavioral Factors:\n\n   * Heavy smoking, defined as consumption of more than 10 cigarettes per day.\n   * Presence of parafunctional habits (e.g., bruxism, clenching) as diagnosed by clinical examination.\n3. Local Oral Factors:\n\n   * Active, untreated periodontal disease in any remaining dentition.\n   * Presence of acute oral infection or pathology at the intended surgical site.\n   * Crown height space less than 15 mm or more than 22 mm.\n   * Insufficient keratinized mucosa (\\\u003C 2 mm width) that cannot be corrected with a simple surgical procedure prior to implant placement.\n4. General:\n\n   * Pregnancy or lactation.\n   * Participation in another interventional clinical trial.\n   * Perceived inability to comply with the study protocol and follow-up schedule.","18 Years","70 Years",{"count":56,"type":22},12,[25],"The goal of this clinical trial is to to compare the prosthetic complication rate and Oral Health-Related Quality of Life (OHRQoL) between screw-retained monolithic zirconia frameworks and CNC-milled titanium frameworks with zirconia superstructures in completely edentulous patients restored with full-arch implant-supported prostheses over a follow-up period of 12 months.",[28],"2026-06-14",{"date":62,"type":38},"2026-06-18",{"date":64,"type":38},"2026-04-12",{"date":66,"type":22},"2027-05",{"name":68,"class":45},"Cairo University",{"id":70,"slug":4,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":71,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":72,"enrollmentInfo":73,"targetDuration":4,"studyType":23,"phases":74,"briefSummary":26,"conditions":75,"keywords":76,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":46},"100638159","Inclusion Criteria:\n\nCompletely edentulous (bimaxillary) Age between 50 and 80 years Able to understand and sign informed consent No cognitive or psychological deficits that interfere with study participation\n\nExclusion Criteria:\n\nUnimaxillary edentulism Presence of Kelly syndrome Presence of flabby tissue on alveolar ridges No prior experience with complete dentures Chronic motor disorders that may compromise prosthetic function","85 Years",{"count":21,"type":22},[25],[28],[30,31,32,33],"2026-05-31",{"date":79,"type":38},"2026-06-04",{"date":81,"type":22},"2026-06-02",{"date":83,"type":22},"2027-10-30",{"name":44,"class":45},{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":4,"enrollmentInfo":92,"targetDuration":4,"studyType":23,"phases":93,"briefSummary":94,"conditions":95,"keywords":96,"overallStatus":104,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":46},"100633309","comparative-study-of-denture-fabrication-techniques-100633309","NCT07525011","Comparative Study of Denture Fabrication Techniques","Comparative Study of Traditional Complete Denture Fabrication Technique and the Easdent Digital Complete Denture Fabrication Technique in a Predoctoral Dental Clinic","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Requiring new dual-arch complete dentures.\n* Willing and able to attend for all required study appointments, including delivery and follow-up visits.\n\nExclusion Criteria:\n\n* Requiring only single-arch complete dentures.\n* Presence of severe medical conditions that would preclude attendance at multiple prosthodontic appointments.\n* Active, untreated oral mucosal disease that would prevent impression making or denture fabrication.\n* Severely resorbed edentulous ridges.\n* Unable or unwilling to attend for all scheduled study visits or follow-up appointments.\n* Unable to comply with instructions necessary for denture treatment or study procedures.",{"count":21,"type":22},[25],"This study is a randomized, single-blinded clinical study conducted in the predoctoral clinic at Rutgers School of Dental Medicine. The purpose of this study is to compare a traditional complete denture fabrication technique with the Easdent digital complete denture workflow. The Easdent technique is a modification of the conventional method and utilizes FDA-approved materials and 3D-printed trays designed to record teeth position, jaw relations and impression information. Participants who require new dual-arch complete dentures will receive dentures fabricated using both techniques. The order of fabrication and delivery will be randomized. Clinical chair time, number of appointments, and total treatment time will be recorded. Patient-reported outcomes will be assessed using a modified OHIP-EDENT survey and preference questions after completion of both dentures. Student participants will also complete surveys evaluating learning experience and clinical usability. The study does not evaluate the safety or effectiveness of a drug or investigational device. All materials used are FDA-cleared and routinely used in clinical practice. The overall aim is to evaluate efficiency, patient satisfaction, and educational usability of the two denture fabrication workflows.",[28],[97,98,99,100,101,102,103],"Complete Denture","Conventional Complete Denture","Digital Complete Denture","Edentulous Patients","Dental Education","Denture Workflow","Removable Prosthodontics","NOT_YET_RECRUITING","2026-04-10",{"date":107,"type":38},"2026-04-13",{"date":109,"type":22},"2026-04-30",{"date":111,"type":22},"2028-05-30",{"name":113,"class":45},"Rutgers, The State University of New Jersey",{"id":115,"slug":116,"hasResults":11,"nctId":117,"briefTitle":118,"officialTitle":118,"acronym":4,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":17,"minAge":120,"maxAge":4,"enrollmentInfo":121,"targetDuration":4,"studyType":23,"phases":123,"briefSummary":124,"conditions":125,"keywords":126,"overallStatus":104,"whyStopped":4,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":46},"100599105","evaluation-of-oral-health-related-quality-of-life-in-patients-with-conventional-complete-dentures-versus-mini-implant-retained-overdentures-a-randomized-clinical-trial-100599105","NCT07080164","Evaluation of Oral Health-Related Quality of Life In Patients With Conventional Complete Dentures Versus Mini-Implant Retained Overdentures: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Completely edentulous mandible for a minimum period of 6 months Adult patients capable of understanding, cooperating, and providing informed consent Sufficient bone volume and interarch space in the anterior mandible to accommodate two mini-implants and overdenture attachments Good general health permitting minor oral surgical procedures Willingness to undergo follow-up visits and comply with study protocols\n\nExclusion Criteria:\n\n* Systemic medical conditions that preclude implant surgery, including poorly controlled chronic diseases such as diabetes mellitus or disorders affecting bone metabolism.\n\nPatients taking medications known to affect bone metabolism (e.g., bisphosphonates, corticosteroids) Patients with physical or mental disabilities that impair oral hygiene maintenance or compliance Heavy smokers (\\>10 cigarettes\u002Fday) Individuals unable or unwilling to attend scheduled follow-up or participate throughout the study duration Patients who can receive standard implants with no anatomical limitations","30 Years",{"count":122,"type":22},24,[25],"Mini-implants have emerged as a practical and less invasive solution for the rehabilitation of edentulous mandibles, offering reduced surgical complexity, lower cost, and faster healing compared to conventional implants. These advantages make them especially suitable for elderly patients or those with systemic health concerns or limited bone volume. Despite their growing clinical use, evidence from well-designed randomized controlled trials evaluating the impact of mini-implant-retained overdentures on patients' oral health-related quality of life (OHRQoL) is still scarce. Establishing this evidence is crucial for guiding treatment decisions in resource-constrained settings and improving the standard of care for edentulous individuals. This research aims to provide high-quality data on the effectiveness of mini-implants in improving OHRQoL, as measured by OHIP-14, compared to conventional dentures.\u002F",[28],[127],"mini-implant overdentures ,OHRQoL ,RCT, Minimally invasive","2025-07-15",{"date":130,"type":38},"2025-07-23",{"date":132,"type":22},"2025-11-01",{"date":134,"type":22},"2027-11-01",{"name":68,"class":45},{"id":137,"slug":138,"hasResults":11,"nctId":139,"briefTitle":140,"officialTitle":140,"acronym":4,"eligibilityCriteria":141,"healthyVolunteers":142,"sex":17,"minAge":143,"maxAge":144,"enrollmentInfo":145,"targetDuration":4,"studyType":23,"phases":146,"briefSummary":147,"conditions":148,"keywords":149,"overallStatus":104,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":4},"100551225","implementation-of-digital-workflow-for-complete-dentures---a-crossover-study-100551225","NCT06457321","Implementation of Digital Workflow for Complete Dentures - A Crossover Study","Inclusion Criteria:\n\n* Patients with complete edentulism requiring complete denture treatments.\n* Prior denture experience.\n* Above the age of 21 years.\n* Medically fit (ASA classification of physical status I-III);\n* Able to write\u002Fread English or Chinese well.\n\nExclusion Criteria:\n\n* New denture wearers.\n* Patients require surgical interventions to correct ridge anatomy.\n* Patients with a history of maladaptation to denture use.\n* Patients with maxillofacial defects.\n* Patients unable to response to the English\u002FChinese questionnaires.\n* Patients with enlarged tuberosity, minimal bone resorption resulting in limited restorative space\n* Patients with enlarged tori\n* Patients with flabby ridge\n* Patients with severely resorbed ridges\n* Patients with severe skeletal relationship discrepancy",true,"21 Years","99 Years",{"count":21,"type":22},[25],"With a demographically ageing population and increasing patients with missing teeth, the demands on the healthcare system are set to further increase. This project is to prepare the public dental healthcare system to remain sustainable in terms of efficiency of denture production and healthcare manpower (lab technicians, clinician and operation staff). It aims to understand and improve denture fabrication productivity, enhance the treatment efficiency. This new model of care is a change from the current staged treatment process to batch processing assisted by new manufacturing methods, with the goal of improving sustainability and effectiveness of existing clinical and dental lab capacities.",[28],[150,151,152,153,154,155,156],"Complete edentulism","Complete denture","Digital Denture","Computer aided design","Computer aided manufacturing","CAD","CAM","2025-05-28",{"date":159,"type":38},"2025-06-03",{"date":161,"type":22},"2025-10-30",{"date":163,"type":22},"2027-12-31",{"name":165,"class":45},"National Dental Centre, Singapore",{"id":167,"slug":168,"hasResults":11,"nctId":169,"briefTitle":170,"officialTitle":171,"acronym":4,"eligibilityCriteria":172,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":173,"targetDuration":4,"studyType":23,"phases":175,"briefSummary":176,"conditions":177,"keywords":178,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":182,"lastUpdatePostDateStruct":183,"startDateStruct":185,"completionDateStruct":187,"leadSponsor":189,"locationsCount":46},"100581154","patient-satisfaction-with-intra-oral-vs-extra-oral-scanned-3d-printed-dentures-an-in-vivo-study-100581154","NCT06846619","\"Patient Satisfaction with Intra-Oral Vs. Extra-Oral Scanned 3D-Printed Dentures: an in Vivo Study\"","Patient Satisfaction of Intra-orally Scanned Versus Extra-orally Scanned Digitally Printed Maxillary Denture in Completely Edentulous Patients, in Vivo Study.","Inclusion Criteria:\n\n* Completely edentulous patients\n* Angle's Class I skeletal relationship\n* Normal facial symmetry\n* Cooperative patients\n\nExclusion Criteria:\n\n* -Temporomandibular disorders\n* Uncontrolled diabetes\n* Patient's with neuromuscular disorders\n* Severe psychiatric disorders\n* Angle's class II and III skeletal relationship.",{"count":174,"type":22},8,[25],"The goal of this clinical trial is to evaluate patient satisfaction with intra-orally scanned versus extra-orally scanned digitally printed maxillary dentures in completely edentulous patients. The main questions it aims to answer are:\n\n1. Do intra-orally scanned dentures provide higher patient satisfaction compared to extra-orally scanned dentures?\n2. Are there significant differences in comfort, fit, aesthetics and phonetics between the two types of dentures?\n\nResearchers will compare the intra-orally scanned denture group to the extra-orally scanned denture group to determine if one method leads to superior patient-reported outcomes.\n\nParticipants will:\n\n* Receive both types of dentures (intra-orally scanned and extra-orally scanned), with a three-week wash-out period between each intervention.\n* Complete satisfaction surveys to assess comfort, fit, and aesthetics after using each type of denture.\n\nThe study aims to provide evidence on the optimal scanning method for digitally printed maxillary dentures in edentulous patients.",[28],[179,180,150,181],"Intraoral scanning","Extra oral scaning","Digital","2025-02-20",{"date":184,"type":38},"2025-02-26",{"date":186,"type":38},"2023-12-03",{"date":188,"type":22},"2025-09-01",{"name":68,"class":45},{"id":191,"slug":192,"hasResults":11,"nctId":193,"briefTitle":194,"officialTitle":195,"acronym":4,"eligibilityCriteria":196,"healthyVolunteers":142,"sex":17,"minAge":18,"maxAge":197,"enrollmentInfo":198,"targetDuration":4,"studyType":23,"phases":200,"briefSummary":201,"conditions":202,"keywords":208,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":214,"lastUpdatePostDateStruct":215,"startDateStruct":217,"completionDateStruct":219,"leadSponsor":221,"locationsCount":46},"100571701","evaluation-of-bone-changes-around-implants-in-patients-treated-with-all-on-four-100571701","NCT06723678","Evaluation of Bone Changes Around Implants in Patients Treated With All on Four","Radiographic Evaluation of Crestal Bone Changes Around Implants in Patients Treated With Delayed Loaded All on Four (Randomized Clinical Trail)","Inclusion Criteria:\n\n* All patients' ages must range from 50-65 years old.\n* All patients' ridges should be covered with firm mucosa free from any signs of inflammation or ulceration and exhibit adequate height and width of the residual alveolar ridge.\n* Patients should be free from any metabolic or bone disorders that contraindicate implant installation.\n* All patients must have sufficient inter arch space\n\nExclusion Criteria:\n\n* Patients with oral or systemic diseases.\n* Patients with xerostomia or excessive salivation.\n* Patients with parafunctional habits (bruxism or clenching).\n* Heavy smoker or alcoholic patients.\n* Patients with history of temporo-mandibular dysfunction.\n* Patients with brain disorders or psychiatric disorders","65 Years",{"count":199,"type":22},16,[25],"The Goal of the clinical trail is to evaluate the Bone height changes around two axially placed anterior implants and two distally inclined 30-degree angle posterior implants in comparison to two axially placed anterior implants and two distally inclined 45-degree angle posterior implants using cone beam CT (CBCT).\n\nPatients will visit the clinic after the surgery and after the framework and denture insertion for check ups and during the follow up periods ( at denture insertion, 6 months and 12 months)",[203,28,204,205,206,207],"Edentulous Alveolar Ridge In Mandible","All on Four Technique","Dental Implant","Edentulous Jaws","Edentulous Mouth",[209,210,211,212,213],"Completely edentulous patients","Dental Implants","All on four technique","Fixed Detachable Prosthesis","screw retained prosthesis","2024-12-08",{"date":216,"type":38},"2024-12-12",{"date":218,"type":38},"2024-11-26",{"date":220,"type":22},"2026-01-01",{"name":222,"class":45},"Al-Azhar University",{"id":224,"slug":225,"hasResults":11,"nctId":226,"briefTitle":227,"officialTitle":228,"acronym":229,"eligibilityCriteria":230,"healthyVolunteers":11,"sex":17,"minAge":53,"maxAge":4,"enrollmentInfo":231,"targetDuration":4,"studyType":23,"phases":233,"briefSummary":234,"conditions":235,"keywords":236,"overallStatus":104,"whyStopped":4,"lastUpdateSubmitDate":242,"lastUpdatePostDateStruct":243,"startDateStruct":245,"completionDateStruct":247,"leadSponsor":249,"locationsCount":4},"100569802","simplified-technique-in-removable-complete-prosthesis-versus-conventional-technique-in-edentulous-patients-100569802","NCT06698978","Simplified Technique in Removable Complete Prosthesis Versus Conventional Technique in Edentulous Patients","Interest of a Simplified Technique in Removable Complete Prosthesis Versus Conventional Technique in Edentulous Patients: a Multicenter Randomized Clinical Trial in Cross-over.","IDEFIX","Inclusion Criteria:\n\n* Patients 18 years\n* Complete single-maxillary (upper or lower arcade) or bimaxillar (upper and lower arcade) edentesis paired with non-iatrogenic removable full dentures (possibly readapted)\n* Edentulous arcade with healthy or sanitized mucosa\n* Sufficient inter arcade space\n* Free and informed consent\n* Adequate understanding of written and spoken French\n* Membership of a social security scheme\n\nExclusion Criteria:\n\n* Patient unable to cooperate\n* Presence of pathological lesions of the oral mucosa\n* Parkinson's disease\n* Gougerot-Sjögren's disease,\n* Patient with cancer of the upper aerogribogastic tract\n* Patient in psychiatric care\n* Patient with neurological disease (vascular algia of the face, trigeminal neuralgia,...)\n* Patient with xerostomia\n* Allergy identified to resin\n* Patient deprived of liberty by judicial or administrative decision\n* Patient under legal protection (guardianship, curatorship)\n* Patient under AME (State Medical Aid)",{"count":232,"type":22},62,[25],"This study compares a simplified complete removable denture technique (PS) to the conventional approach (PC) in edentulous patients. The goal is to demonstrate that the simplified technique is not inferior to the conventional method in terms of quality of life, measured by the OHIP-20 scale over three months. The trial also examines time, satisfaction, denture quality, cost, and masticatory performance.\n\nDesign:\n\nThis is a multicenter, randomized, cross-over study with 62 patients over 11 months of participation, including a one-month washout between treatments. Patients will receive both types of dentures, with the order randomized.\n\nPopulation:\n\nThe trial targets edentulous patients, both uni- and bi-maxillary, aged 18 or older, with certain health and dental conditions.\n\nKey Assessments:\n\nQuality of Life: OHIP-20 scores are collected pre-treatment and after three months for each denture type.\n\nPatient Satisfaction and Denture Quality: Assessed using modified Kapur criteria and patient satisfaction surveys.\n\nMasticatory Performance: Evaluated with a chewing gum test. Medical Economic Impact: Cost analysis of each denture type.\n\nAnticipated Outcomes:\n\nBenefits include reducing costs and treatment times, enhancing accessibility to dentures, particularly for elderly and underserved populations, and adapting dental education to teach this simplified technique.\n\nCenters Involved:\n\nSeven centers across France, including AP-HP hospitals and private practices.\n\nTimeline:\n\nThe inclusion period is 24 months, with a total study duration of 35 months.",[28],[237,238,239,240,241],"removable prosthesis","simplified technique","cross-over","edentulous patients","conventional technique","2024-11-19",{"date":244,"type":38},"2024-11-21",{"date":246,"type":22},"2025-01-01",{"date":248,"type":22},"2028-03-01",{"name":250,"class":45},"Assistance Publique - Hôpitaux de Paris",{"id":252,"slug":253,"hasResults":11,"nctId":254,"briefTitle":255,"officialTitle":256,"acronym":257,"eligibilityCriteria":258,"healthyVolunteers":142,"sex":259,"minAge":18,"maxAge":260,"enrollmentInfo":261,"targetDuration":4,"studyType":23,"phases":262,"briefSummary":263,"conditions":264,"keywords":265,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":270,"lastUpdatePostDateStruct":271,"startDateStruct":273,"completionDateStruct":275,"leadSponsor":277,"locationsCount":46},"100565576","patient-satisfaction-and-crestal-bone-changes-around-one-piece-zirconiazr-and-titaniumti-in-implant-retained-mandibular-overdenture-100565576","NCT06643975","Patient Satisfaction and Crestal Bone Changes Around One-piece Zirconia(Zr) and Titanium(Ti) in Implant-Retained Mandibular Overdenture","Assessment of Patient Satisfaction and Crestal Bone Changes Around One-piece Zirconia and Titanium Implants in Mandibular Implant-Retained Overdenture: A Randomized Clinical Trial","(Zr) - (Ti)","Inclusion Criteria:\n\n* Male patients\n* The age range of 50 to 60 years old (average of 55).\n* moderately developed mandibular residual ridges, covered with healthy mucosa, firmly attached to the underling bone and with average mucosal thickness (2-3) mm.\n* At least 12 mm of vertical bone height in the mandible allowing for placement of a 10 mm implant (2 mm safety distance to inferior alveolar nerve).\n* Patients were selected with Angle class-I maxillomandibular relationship with sufficient inter-arch space (13-15mm\n\nExclusion Criteria:\n\n* Heavy smokers of more than 10 cigarettes a day\n* Poor oral hygiene.\n* Patients with temporomandibular joint disorders(TMD),\n* Patients suffered of xerostomia,\n* Patients exhibited Para-functional habits, or recent extractions were excluded.\n* Patients with systemic diseases that might affect bone quality or quantity, or retard healing of the surgical wounds were excluded.\n* Patients receiving intravenous forms of bisphosphonates.\n* Patients who have had radiation therapy to the head and neck region.\n* Patients with existing implants in the jaws\n* Patients with previous bone grafting in either the maxillary or mandibular jaws.","MALE","60 Years",{"count":21,"type":22},[25],"This interventional randomized clinical trial study is conducted to assess patient satisfaction and crestal bone changes around one-piece Zr and Ti Implants in mandibular implant-retained overdenture in completely edentulous male patients in the age group between (50-60)years old to know if there will be a significant difference between the two types of dental implants through 12 months after the definitive prosthetic loading",[28],[266,267,268,269],"Zirconia","One-piece","Overdenture","Implant","2024-10-19",{"date":272,"type":38},"2024-10-22",{"date":274,"type":38},"2024-06-15",{"date":276,"type":22},"2025-10-15",{"name":278,"class":45},"Ain Shams University"]