[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"complex-regional-pain-syndrome\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:complex-regional-pain-syndrome":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,43,67,94],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100627290","hyperbaric-oxygen-therapy-in-complex-regional-pain-syndrome-100627290",false,"NCT07446712","Hyperbaric Oxygen Therapy in Complex Regional Pain Syndrome","Hyperbaric Oxygen Therapy in Complex Regional Pain Syndrome: a Randomised Controlled Trial","Inclusion Criteria:\n\n\\- Diagnosis of CRPS Type I (without nerve injury)\n\nExclusion Criteria:\n\n* HBOT contraindications (pregnancy; use of bleomycin, cisplatin, disulfiram, and doxorubicin; middle ear surgery; untreated pneumothorax or pneumomediastinum; ongoing acute infection; severe decompensation of organ functions or organ failure, severe claustrophobia)\n* Inability to sign the consent form","ALL","18 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","The aim of the study is to investigate the efficacy of hyperbaric oxygen therapy as an adjunct in the management of severe complex regional pain syndrome.",[26,27],"Chronic Pain","Complex Regional Pain Syndrome",[27,26,29],"Hyperbaric Oxygen Therapy","NOT_YET_RECRUITING","2026-02-25",{"date":33,"type":34},"2026-03-03","ACTUAL",{"date":36,"type":20},"2026-04",{"date":38,"type":20},"2029-04",{"name":40,"class":41},"University Hospital Ostrava","OTHER",2,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":21,"phases":53,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":56,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":66},"100247636","low-dose-naltrexone-for-the-treatment-of-complex-regional-pain-syndrome-100247636","NCT02502162","Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome","LDN-CRPS","Inclusion Criteria:\n\n* Upper and\u002For lower extremity CRPS\n* On stable treatment for 1 month\n* CRPS for at least 1 year\n* Meet the Budapest criteria for CRPS at time of the study.\n\nExclusion Criteria:\n\n* Any known allergy to naltrexone or naloxone\n* Use of prescription opioid analgesics or illegal opioid use\n* Current or planned pregnancy.","70 Years",{"count":52,"type":20},120,[23],"The investigators are testing treatment with low-dose naltrexone (LDN) for symptom relief of complex regional pain syndrome (CRPS). Study participants will be randomly assigned to receive either LDN or placebo for a period of several weeks. During this period participants will be asked to attend either in-person or virtual study visits and complete questionnaires.",[27],"RECRUITING","2025-05-27",{"date":59,"type":34},"2025-05-29",{"date":61,"type":4},"2015-06",{"date":63,"type":20},"2027-07",{"name":65,"class":41},"Stanford University",1,{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":50,"enrollmentInfo":74,"targetDuration":4,"studyType":21,"phases":76,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":56,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":66},"100575214","the-effects-of-whirlpool-and-contrast-bath-in-patients-with-complex-regional-pain-syndrome-after-distal-radius-fracture-100575214","NCT06769373","The Effects of Whirlpool and Contrast Bath in Patients with Complex Regional Pain Syndrome After Distal Radius Fracture","The Effects of Whirlpool Bath and Contrast Bath Treatments on Pain, Disability, Functionality and Grip Strength in Patients with Complex Regional Pain Syndrome After Distal Radius Fracture","Inclusion Criteria:\n\n* Patients with complex regional pain syndrome type-1 (CRPS-type 1) after distal radius fracture, who were followed conservatively (long\u002Fshort arm splint-cast) between the ages of 18-70, who applied to AFSU Physical Medicine and Rehabilitation Clinic. It is planned to use the Budapest diagnostic criteria for the diagnosis of CRPS Type 1.\n\nExclusion Criteria:\n\n* Orthopedic injuries (other accompanying orthopedic fractures, such as ulna fracture, carpal bone fractures),\n* Other system injuries,\n* Patients whose distal radius fractures were surgically treated,\n* Patients who had previously undergone surgery on the same upper extremity,\n* Nerve, tendon and artery injuries accompanying the fracture,\n* Other neurological, orthopedic or rheumatological problems affecting the same upper extremity,\n* Serious cardiovascular disease,\n* Presence of active infection, active dermatitis, skin diseases such as pemphigus, febrile diseases,\n* Presence of a fixed catheter in the area,\n* Impaired temperature sensationin in the area.",{"count":75,"type":20},40,[23],"The aim of our study is to investigate the effects of whirlpool bath and contrast bath treatments on pain, disability, functionality and grip strength in patients with complex regional pain syndrome after distal radius fracture.",[79,80,27],"Distal Radius Fracture","Complex Regional Pain Syndrome Type I",[82,83,84],"Whirlpool","Contrast bath","hydrotherapy","2025-01-28",{"date":87,"type":34},"2025-01-30",{"date":89,"type":20},"2025-01-31",{"date":91,"type":20},"2025-06-15",{"name":93,"class":41},"Afyonkarahisar Health Sciences University",{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":4,"eligibilityCriteria":100,"healthyVolunteers":11,"sex":16,"minAge":101,"maxAge":102,"enrollmentInfo":103,"targetDuration":4,"studyType":21,"phases":105,"briefSummary":107,"conditions":108,"keywords":109,"overallStatus":56,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":42},"100546297","phase-1-the-effects-and-mechanisms-of-a-high-cbd-cannabis-extract-brc-002-for-the-treatment-of-pain-and-health-in-complex-regional-pain-syndrome-100546297","NCT06393101","The Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome","A Randomized, Double-blind, Placebo-controlled Study to Investigate the Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome","Inclusion Criteria:\n\n1. Provision of signed and dated informed consent form.\n2. Are between 21-75 years old\n3. Ability to communicate in English\n4. Volunteers with no previous medical history (e.g., cardiac or pulmonary disease)\n5. Are not currently using any type of cannabis, including hemp or CBD\n6. Currently 30 days cannabis free\n7. Participants with ongoing CRPS \\[Type 1 or Type 2)\\] for at least 3 months prior to participation (medical record confirmed)\n8. Agrees not to use cannabis, including hemp or CBD, outside of the study during participation in the study\n9. Agrees not to use opioids or barbiturates during participation in the study\n\nExclusion Criteria:\n\n1. Fail cannabis screening\n2. Active pulmonary disease\n3. Allergy or past adverse effects or negative past experiences from cannabis\n4. Positive urine drug test for THC, barbiturates, opioids, oxycodone, or methadone prior to study session 1 or session 2\n5. Any significant illness, including cardiovascular disease, diabetes, renal and liver disease\n6. Any current or history of an immunocompromising disease or condition (such as lupus, psoriasis, multiple sclerosis, etc.)\n7. Any current or history of neurologic conditions, including Parkinson disease, dementia, cognitive impairment, history of seizure disorder, and history of traumatic brain injury\u002Fhead injury\n8. Participant meets DSM-V criteria for current major psychiatric illness, such as bipolar disorder, major depression, psychosis, substance use disorder, or schizophrenia\n9. Any current or history of suicidal ideation or attempt\n10. Patients with clinically significant laboratory abnormalities","21 Years","75 Years",{"count":104,"type":20},52,[106],"PHASE1","The aim of this trial is to determine the potential effects and mechanisms of cannabinoid-induced pain relief in complex regional pain syndrome (CRPS). Multiple psychophysical approaches will be conducted in conjunction with psychological and inflammatory marker testing to determine if and how cannabinoids produce stabilized improvement in CRPS-related pain and comorbidities.\n\nThe trial consisted of a pre-treatment screening period, six-week treatment period and a two-week follow-up.",[27],[27,110,111,112],"CRPS","Cannabis","Pain","2024-06-05",{"date":115,"type":34},"2024-06-07",{"date":117,"type":20},"2024-06-01",{"date":119,"type":20},"2029-06-01",{"name":121,"class":41},"University of California, San Diego"]